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Volumn , Issue 1, 2011, Pages 19-46

Synthesis of limonoid natural products

Author keywords

Azadirachtin; Limonoid; Natural products; Polyolefin carbocyclization; Steroids; Terpenoids

Indexed keywords


EID: 78650840784     PISSN: 1434193X     EISSN: 10990690     Source Type: Journal    
DOI: 10.1002/ejoc.201001218     Document Type: Review
Times cited : (55)

References (165)
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    • For general reviews on limonoid natural products, see
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    • For a commentary on the exercise of synthesizing molecules such as 150, see the following news item
    • For a commentary on the exercise of synthesizing molecules such as 150, see the following news item: Nature 2007, 448, 630-631.
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    • Ref. 8 reports that application of various allylic oxidation procedures to pyroangolensolide provided, at best, a 17% yield of azadarelide (44) along with side-products.
    • Ref. 8 reports that application of various allylic oxidation procedures to pyroangolensolide provided, at best, a 17% yield of azadarelide (44) along with side-products.
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    • The C-seco limonoid azadirachtin (150) has also been prepared by total synthesis but does not contain an intact furanylsteroid carbon skeleton. This achievement will be discussed in Section 4.4 of this work.
    • The C-seco limonoid azadirachtin (150) has also been prepared by total synthesis but does not contain an intact furanylsteroid carbon skeleton. This achievement will be discussed in Section 4.4 of this work.
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    • For selected examples from the Corey laboratory of biomimetic total syntheses based on polyolefin carbocyclization, see
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    • Selected examples
    • Selected examples
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    • This term ("the C8-C14 problem") makes reference to the comparably vexing "C20 problem" of steroid synthesis
    • This term ("the C8-C14 problem") makes reference to the comparably vexing "C20 problem" of steroid synthesis
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    • For general information and leading references regarding limonoid biosynthesis, see ref. 3a-b.
    • For general information and leading references regarding limonoid biosynthesis, see ref. 3a-b.
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    • Bradshaw and Bonjoch have very recently described a catalytic preparation of large quantities of highly enantio-enriched 161 that avoids multiple purifications and recrystallizations:, B. Bradshaw, G. Etxebarria-Jardi, J. Bonjoch, J. Am. Chem. Soc. 2010, 132, 5966-5967.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.