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Volumn 121, Issue 51, 1999, Pages 12206-12207

Enantioselective total synthesis of the kinesin motor protein inhibitor adociasulfate 1 [12]

Author keywords

[No Author keywords available]

Indexed keywords

ADOCIASULFATE 1; KINESIN; MOLECULAR MOTOR; SULFATE; UNCLASSIFIED DRUG;

EID: 0040340134     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9934091     Document Type: Letter
Times cited : (64)

References (31)
  • 1
    • 0032559260 scopus 로고    scopus 로고
    • Hirokawa, N. Science 1998, 279, 519-526.
    • (1998) Science , vol.279 , pp. 519-526
    • Hirokawa, N.1
  • 8
    • 0001140189 scopus 로고
    • Trost, B. M., Fleming, I., Eds.; Pergamon: Oxford
    • For a recent review, see: Sutherland, J. K. In Comprehensive Organic Synthesis; Trost, B. M., Fleming, I., Eds.; Pergamon: Oxford, 1991; Vol. 3, pp 341-377.
    • (1991) Comprehensive Organic Synthesis , vol.3 , pp. 341-377
    • Sutherland, J.K.1
  • 11
    • 0343400472 scopus 로고    scopus 로고
    • note
    • 10
  • 21
    • 0342965277 scopus 로고    scopus 로고
    • note
    • To our knowledge this is the first use of a lanthanide triflate to catalyze a polyene cyclization.
  • 23
    • 0342531004 scopus 로고    scopus 로고
    • note
    • The authors have deposited coordinates for this compound with the Cambridge Crystallographic Data Centre. The coordinates can be obtained, on request, from the Director, Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge, CB2 1EZ, U.K.
  • 24
    • 0343836204 scopus 로고    scopus 로고
    • note
    • 22
  • 26
    • 0342965275 scopus 로고    scopus 로고
    • note
    • 2, imidazole, benzene) followed by lithium-iodide exchange using tert-butyllithium.
  • 30
    • 0343836203 scopus 로고    scopus 로고
    • note
    • 19F NMR.
  • 31
    • 0343400471 scopus 로고    scopus 로고
    • note
    • The synthetic sequence is 28 steps from either starting material.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.