Rate limiting step precedes C-C bond formation in the archetypical proline-catalyzed intramolecular aldol reaction

Journal of the American Chemical Society

Volumn 131, Issue 5, 2009, Pages 1632-1633

  Zhu, Hui ^a   Clemente, Fernando R ^b   Houk, K N ^b   Meyer, Matthew P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C-C BOND FORMATION; CARBON-CARBON BOND FORMATION; CATALYZED CONVERSION; EXPERIMENTAL MEASUREMENTS; INTRAMOLECULAR ALDOL REACTIONS; KINETIC ISOTOPE EFFECTS; MECHANISTIC STUDIES; MODEL REACTIONS; RATE LIMITING; RATE-LIMITING STEPS;

ISOTOPES;

CARBON; CARBON 13; PROLINE; BICYCLO COMPOUND; KETONE;

ALDOL REACTION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CATALYST; CHEMICAL ANALYSIS; CHEMICAL BOND; CHEMICAL STRUCTURE; FRACTIONATION; CHEMISTRY; CYCLIZATION; KINETICS; SYNTHESIS;

BICYCLO COMPOUNDS; CATALYSIS; CYCLIZATION; KETONES; KINETICS; PROLINE;

EID: 67749118136     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja806672y     Document Type: Article

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