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Volumn 6, Issue 1, 2007, Pages 25-37

The Nuclear Receptor ERRα Is Required for the Bioenergetic and Functional Adaptation to Cardiac Pressure Overload

Author keywords

DEVBIO; HUMDISEASE

Indexed keywords

ADENOSINE TRIPHOSPHATE; CELL NUCLEUS RECEPTOR; CREATINE PHOSPHATE; ESTROGEN RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATE; BIOLOGICAL MARKER; ERRALPHA ESTROGEN RELATED RECEPTOR; ERRALPHA ESTROGEN-RELATED RECEPTOR; ESTROGEN RECEPTOR; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1; PEROXISOME-PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA COACTIVATOR-1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 34347248013     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2007.06.005     Document Type: Article
Times cited : (238)

References (54)
  • 3
    • 0018146427 scopus 로고
    • Absolute morphometric study of myocardial hypertrophy in experimental hypertension. II. Ultrastructure of myocytes and interstitium
    • Anversa P., Loud A.V., Giacomelli F., and Weiner J. Absolute morphometric study of myocardial hypertrophy in experimental hypertension. II. Ultrastructure of myocytes and interstitium. Lab. Invest. 38 (1978) 597-609
    • (1978) Lab. Invest. , vol.38 , pp. 597-609
    • Anversa, P.1    Loud, A.V.2    Giacomelli, F.3    Weiner, J.4
  • 4
  • 5
    • 33745627066 scopus 로고    scopus 로고
    • Transverse aortic constriction leads to accelerated heart failure in mice lacking PPARγ coactivator 1α
    • Arany Z., Novikov M., Chin S., Ma Y., Rosenzweig A., and Spiegelman B.M. Transverse aortic constriction leads to accelerated heart failure in mice lacking PPARγ coactivator 1α. Proc. Natl. Acad. Sci. USA 103 (2006) 10086-10091
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 10086-10091
    • Arany, Z.1    Novikov, M.2    Chin, S.3    Ma, Y.4    Rosenzweig, A.5    Spiegelman, B.M.6
  • 6
    • 0037407012 scopus 로고    scopus 로고
    • Hypertrophic cardiomyopathy: a paradigm for myocardial energy depletion
    • Ashrafian H., Redwood C., Blair E., and Watkins H. Hypertrophic cardiomyopathy: a paradigm for myocardial energy depletion. Trends Genet. 19 (2003) 263-268
    • (2003) Trends Genet. , vol.19 , pp. 263-268
    • Ashrafian, H.1    Redwood, C.2    Blair, E.3    Watkins, H.4
  • 9
    • 27444441492 scopus 로고    scopus 로고
    • Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity
    • Boudina S., Sena S., O'Neill B.T., Tathireddy P., Young M.E., and Abel E.D. Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity. Circulation 112 (2005) 2686-2695
    • (2005) Circulation , vol.112 , pp. 2686-2695
    • Boudina, S.1    Sena, S.2    O'Neill, B.T.3    Tathireddy, P.4    Young, M.E.5    Abel, E.D.6
  • 10
    • 10644274243 scopus 로고    scopus 로고
    • Estrogen-related receptor α (ERRα) is a transcriptional regulator of apolipoprotein A-IV and controls lipid handling in the intestine
    • Carrier J.C., Deblois G., Champigny C., Levy E., and Giguere V. Estrogen-related receptor α (ERRα) is a transcriptional regulator of apolipoprotein A-IV and controls lipid handling in the intestine. J. Biol. Chem. 279 (2004) 52052-52058
    • (2004) J. Biol. Chem. , vol.279 , pp. 52052-52058
    • Carrier, J.C.1    Deblois, G.2    Champigny, C.3    Levy, E.4    Giguere, V.5
  • 11
    • 0027972866 scopus 로고
    • Altered glucose and fatty acid oxidation in hearts of the spontaneously hypertensive rat
    • Christe M.D., and Rodgers R.L. Altered glucose and fatty acid oxidation in hearts of the spontaneously hypertensive rat. J. Mol. Cell. Cardiol. 26 (1994) 1371-1375
    • (1994) J. Mol. Cell. Cardiol. , vol.26 , pp. 1371-1375
    • Christe, M.D.1    Rodgers, R.L.2
  • 12
    • 0036073044 scopus 로고    scopus 로고
    • 2+ loading and adrenergic stimulation reveal male/female differences in susceptibility to ischemia-reperfusion injury
    • 2+ loading and adrenergic stimulation reveal male/female differences in susceptibility to ischemia-reperfusion injury. Am. J. Physiol. 283 (2002) H481-H489
    • (2002) Am. J. Physiol. , vol.283
    • Cross, H.1    Murphy, E.2    Steenbergen, C.3
  • 13
    • 0037219524 scopus 로고    scopus 로고
    • Myocardial fatty acid metabolism: independent predictor of left ventricular mass in hypertension and in left ventricular dysfunction
    • de las Fuentes L., Herrero P., Peterson L.R., Kelly D.P., Gropler R.J., and Davila-Roman V.G. Myocardial fatty acid metabolism: independent predictor of left ventricular mass in hypertension and in left ventricular dysfunction. Hypertension 41 (2003) 83-87
    • (2003) Hypertension , vol.41 , pp. 83-87
    • de las Fuentes, L.1    Herrero, P.2    Peterson, L.R.3    Kelly, D.P.4    Gropler, R.J.5    Davila-Roman, V.G.6
  • 14
    • 0026954617 scopus 로고
    • Cardiac metabolism in patients with dilated and hypertrophic cardiomyopathy: Assessment with proton-decoupled P-31 MR spectroscopy
    • de Roos A., Doornbos J., Luyten P., Oosterwaal L., van der Wall E., and den Hollander J. Cardiac metabolism in patients with dilated and hypertrophic cardiomyopathy: Assessment with proton-decoupled P-31 MR spectroscopy. J. Magn. Reson. Imaging 2 (1992) 711-719
    • (1992) J. Magn. Reson. Imaging , vol.2 , pp. 711-719
    • de Roos, A.1    Doornbos, J.2    Luyten, P.3    Oosterwaal, L.4    van der Wall, E.5    den Hollander, J.6
  • 16
    • 33644660537 scopus 로고    scopus 로고
    • PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease
    • Finck B.N., and Kelly D.P. PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease. J. Clin. Invest. 116 (2006) 615-622
    • (2006) J. Clin. Invest. , vol.116 , pp. 615-622
    • Finck, B.N.1    Kelly, D.P.2
  • 17
    • 0141634243 scopus 로고    scopus 로고
    • Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles
    • Garnier A., Fortin D., Deloménie C., Momken I., Veksler V., and Ventura-Clapier R. Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles. J. Physiol. 551 (2003) 491-501
    • (2003) J. Physiol. , vol.551 , pp. 491-501
    • Garnier, A.1    Fortin, D.2    Deloménie, C.3    Momken, I.4    Veksler, V.5    Ventura-Clapier, R.6
  • 18
    • 33644695373 scopus 로고    scopus 로고
    • Regulation of muscle GLUT4 enhancer factor and myocyte enhancer factor 2 by AMP-activated protein kinase
    • Holmes B.F., Sparling D.P., Olson A.L., Winder W.W., and Dohm G.L. Regulation of muscle GLUT4 enhancer factor and myocyte enhancer factor 2 by AMP-activated protein kinase. Am. J. Physiol. Endocrinol. Metab. 289 (2005) 1071-1076
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.289 , pp. 1071-1076
    • Holmes, B.F.1    Sparling, D.P.2    Olson, A.L.3    Winder, W.W.4    Dohm, G.L.5
  • 19
    • 14644425217 scopus 로고    scopus 로고
    • Mitochondrial energy metabolism in heart failure: A question of balance
    • Huss J.M., and Kelly D.P. Mitochondrial energy metabolism in heart failure: A question of balance. J. Clin. Invest. 115 (2005) 547-555
    • (2005) J. Clin. Invest. , vol.115 , pp. 547-555
    • Huss, J.M.1    Kelly, D.P.2
  • 20
    • 0037174798 scopus 로고    scopus 로고
    • PGC-1α coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-α and -γ
    • Huss J.M., Kopp R.P., and Kelly D.P. PGC-1α coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-α and -γ. J. Biol. Chem. 277 (2002) 40265-40274
    • (2002) J. Biol. Chem. , vol.277 , pp. 40265-40274
    • Huss, J.M.1    Kopp, R.P.2    Kelly, D.P.3
  • 21
    • 4744371376 scopus 로고    scopus 로고
    • ERRα directs PPARα signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle
    • Huss J.M., Pinéda Torra I., Staels B., Giguère V., and Kelly D.P. ERRα directs PPARα signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle. Mol. Cell. Biol. 24 (2004) 9079-9091
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9079-9091
    • Huss, J.M.1    Pinéda Torra, I.2    Staels, B.3    Giguère, V.4    Kelly, D.P.5
  • 22
    • 0035665581 scopus 로고    scopus 로고
    • Physiological and pathological cardiac hypertrophy induce different molecular phenotypes in the rat
    • Iemitsu M., Miyazaki H., Matsuda M., and Yamaguchi I. Physiological and pathological cardiac hypertrophy induce different molecular phenotypes in the rat. Am. J. Physiol. 281 (2001) R2029-R2036
    • (2001) Am. J. Physiol. , vol.281
    • Iemitsu, M.1    Miyazaki, H.2    Matsuda, M.3    Yamaguchi, I.4
  • 23
    • 4944265466 scopus 로고    scopus 로고
    • Transgenic expression of Bcl-2 modulates energy metabolism, prevents cytosolic acidification during ischemia, and reduces ischemia/reperfusion injury
    • Imahashi K., Schneider M.D., Steenbergen C., and Murphy E. Transgenic expression of Bcl-2 modulates energy metabolism, prevents cytosolic acidification during ischemia, and reduces ischemia/reperfusion injury. Circ. Res. 95 (2004) 734-741
    • (2004) Circ. Res. , vol.95 , pp. 734-741
    • Imahashi, K.1    Schneider, M.D.2    Steenbergen, C.3    Murphy, E.4
  • 25
    • 3342967512 scopus 로고    scopus 로고
    • Is the failing heart energy starved? On using chemical energy to support cardiac function
    • Ingwall J.S., and Weiss R.G. Is the failing heart energy starved? On using chemical energy to support cardiac function. Circ. Res. 95 (2004) 135-145
    • (2004) Circ. Res. , vol.95 , pp. 135-145
    • Ingwall, J.S.1    Weiss, R.G.2
  • 26
    • 0026493773 scopus 로고
    • Diffusion distances, total capillary length, and mitochondrial volume in pressure overload myocardial hypertrophy
    • Kayar S.R., and Weiss H.R. Diffusion distances, total capillary length, and mitochondrial volume in pressure overload myocardial hypertrophy. J. Mol. Cell. Cardiol. 24 (1992) 1155-1166
    • (1992) J. Mol. Cell. Cardiol. , vol.24 , pp. 1155-1166
    • Kayar, S.R.1    Weiss, H.R.2
  • 27
  • 28
    • 0036284578 scopus 로고    scopus 로고
    • Gene regulatory mechanisms governing energy metabolism during cardiac hypertrophic growth
    • Lehman J.J., and Kelly D.P. Gene regulatory mechanisms governing energy metabolism during cardiac hypertrophic growth. Heart Fail. Rev. 7 (2002) 175-185
    • (2002) Heart Fail. Rev. , vol.7 , pp. 175-185
    • Lehman, J.J.1    Kelly, D.P.2
  • 30
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • Lin J., Handschin C., and Spiegelman B.M. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 1 (2005) 361-370
    • (2005) Cell Metab. , vol.1 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 31
    • 0242580188 scopus 로고    scopus 로고
    • Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha
    • Luo J., Sladek R., Carrier J., Bader J.A., Richard D., and Giguere V. Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha. Mol. Cell. Biol. 23 (2003) 7947-7956
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 7947-7956
    • Luo, J.1    Sladek, R.2    Carrier, J.3    Bader, J.A.4    Richard, D.5    Giguere, V.6
  • 32
    • 33644874959 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and apoptosis underlie the pathogenic process in α-B-crystallin desmin-related cardiomyopathy
    • Maloyan A., Sanbe A., Osinska H., Westfall M., Robinson D., Imahashi K.-I., Murphy E., and Robbins J. Mitochondrial dysfunction and apoptosis underlie the pathogenic process in α-B-crystallin desmin-related cardiomyopathy. Circulation 112 (2005) 3451-3461
    • (2005) Circulation , vol.112 , pp. 3451-3461
    • Maloyan, A.1    Sanbe, A.2    Osinska, H.3    Westfall, M.4    Robinson, D.5    Imahashi, K.-I.6    Murphy, E.7    Robbins, J.8
  • 34
    • 33947239659 scopus 로고    scopus 로고
    • The failing heart-an engine out of fuel
    • Neubauer S. The failing heart-an engine out of fuel. N. Engl. J. Med. 356 (2007) 1140-1151
    • (2007) N. Engl. J. Med. , vol.356 , pp. 1140-1151
    • Neubauer, S.1
  • 37
    • 0025873338 scopus 로고
    • Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy
    • Rockman H.A., Ross R.S., Harris A.N., Knowlton K.U., Steinhelper M.E., Field L.J., Ross Jr. J., and Chien K.R. Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proc. Natl. Acad. Sci. USA 88 (1991) 8277-8281
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8277-8281
    • Rockman, H.A.1    Ross, R.S.2    Harris, A.N.3    Knowlton, K.U.4    Steinhelper, M.E.5    Field, L.J.6    Ross Jr., J.7    Chien, K.R.8
  • 38
    • 0030923761 scopus 로고    scopus 로고
    • A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program
    • Sack M.N., Disch D.L., Rockman H.A., and Kelly D.P. A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc. Natl. Acad. Sci. USA 94 (1997) 6438-6443
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6438-6443
    • Sack, M.N.1    Disch, D.L.2    Rockman, H.A.3    Kelly, D.P.4
  • 39
    • 0842345401 scopus 로고    scopus 로고
    • Functional coupling as a basic mechanism of feedback regulation of cardiac energy metabolism
    • Saks V.A., Kuznetsov A.V., Vendelin M., Guerrero K., Kay L., and Seppet E.K. Functional coupling as a basic mechanism of feedback regulation of cardiac energy metabolism. Mol. Cell. Biochem. 256-257 (2004) 185-199
    • (2004) Mol. Cell. Biochem. , vol.256-257 , pp. 185-199
    • Saks, V.A.1    Kuznetsov, A.V.2    Vendelin, M.3    Guerrero, K.4    Kay, L.5    Seppet, E.K.6
  • 43
    • 0038660688 scopus 로고    scopus 로고
    • The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor α (ERRα)
    • Schreiber S.N., Knutti D., Brogli K., Uhlmann T., and Kralli A. The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor α (ERRα). J. Biol. Chem. 278 (2003) 9013-9018
    • (2003) J. Biol. Chem. , vol.278 , pp. 9013-9018
    • Schreiber, S.N.1    Knutti, D.2    Brogli, K.3    Uhlmann, T.4    Kralli, A.5
  • 44
    • 20444439185 scopus 로고    scopus 로고
    • Expression profiling reveals differences in metabolic gene expression between exercise-induced cardiac effects and maladaptive cardiac hypertrophy
    • Strøm C.C., Aplin M., Ploug T., Christoffersen T.E.H., Langfort J., Viese M., Galbo H., Haunso S., and Sheikh S.P. Expression profiling reveals differences in metabolic gene expression between exercise-induced cardiac effects and maladaptive cardiac hypertrophy. FEBS J. 272 (2005) 2684-2695
    • (2005) FEBS J. , vol.272 , pp. 2684-2695
    • Strøm, C.C.1    Aplin, M.2    Ploug, T.3    Christoffersen, T.E.H.4    Langfort, J.5    Viese, M.6    Galbo, H.7    Haunso, S.8    Sheikh, S.P.9
  • 45
    • 0036118875 scopus 로고    scopus 로고
    • Mitochondrial proteins in hypertrophy and atrophy: A transcript analysis in rat heart
    • Taegtmeyer H., Razeghi P., and Young M.E. Mitochondrial proteins in hypertrophy and atrophy: A transcript analysis in rat heart. Clin. Exp. Pharmacol. Physiol. 29 (2002) 346-350
    • (2002) Clin. Exp. Pharmacol. Physiol. , vol.29 , pp. 346-350
    • Taegtmeyer, H.1    Razeghi, P.2    Young, M.E.3
  • 46
    • 0035912954 scopus 로고    scopus 로고
    • Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis
    • Tian R., and Abel E.D. Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis. Circulation 103 (2001) 2961-2966
    • (2001) Circulation , vol.103 , pp. 2961-2966
    • Tian, R.1    Abel, E.D.2
  • 47
    • 0029897792 scopus 로고    scopus 로고
    • Depletion of energy reserve via the creatine kinase reaction during the evolution of heart failure in cardiomyopathic hamsters
    • Tian R., Nascimben L., Kaddurah-Daouk R., and Ingwall J.S. Depletion of energy reserve via the creatine kinase reaction during the evolution of heart failure in cardiomyopathic hamsters. J. Mol. Cell. Cardiol. 28 (1996) 755-765
    • (1996) J. Mol. Cell. Cardiol. , vol.28 , pp. 755-765
    • Tian, R.1    Nascimben, L.2    Kaddurah-Daouk, R.3    Ingwall, J.S.4
  • 48
    • 0035089266 scopus 로고    scopus 로고
    • Prognostic implications of left ventricular hypertrophy
    • Vakili B.A., Okin P.M., and Devereux R.B. Prognostic implications of left ventricular hypertrophy. Am. Heart J. 141 (2001) 334-341
    • (2001) Am. Heart J. , vol.141 , pp. 334-341
    • Vakili, B.A.1    Okin, P.M.2    Devereux, R.B.3
  • 50
    • 0033981680 scopus 로고    scopus 로고
    • Mitochondrial defects in cardiomyopathy and neuromuscular disease
    • Wallace D.C. Mitochondrial defects in cardiomyopathy and neuromuscular disease. Am. Heart J. 139 (2000) S70-S85
    • (2000) Am. Heart J. , vol.139
    • Wallace, D.C.1
  • 52
    • 14144256552 scopus 로고    scopus 로고
    • ATP flux through creatine kinase in the normal, stressed, and failing human heart
    • Weiss R.G., Gerstenblith G., and Bootomley P.A. ATP flux through creatine kinase in the normal, stressed, and failing human heart. Proc. Natl. Acad. Sci. USA 102 (2005) 808-813
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 808-813
    • Weiss, R.G.1    Gerstenblith, G.2    Bootomley, P.A.3
  • 53
    • 28544438180 scopus 로고    scopus 로고
    • PGC-1α coactivates PDK4 gene expression via the orphan nuclear receptor ERRα: A mechanism for transcriptional control of muscle glucose metabolism
    • Wende A.R., Huss J.M., Schaeffer P.J., Giguère V., and Kelly D.P. PGC-1α coactivates PDK4 gene expression via the orphan nuclear receptor ERRα: A mechanism for transcriptional control of muscle glucose metabolism. Mol. Cell. Biol. 25 (2005) 10684-10694
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 10684-10694
    • Wende, A.R.1    Huss, J.M.2    Schaeffer, P.J.3    Giguère, V.4    Kelly, D.P.5


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