A CamKIIα iCre BAC allows brain-specific gene inactivation

Genesis (United States)

Volumn 31, Issue 1, 2001, Pages 37-42

  Casanova, E ^a   Fehsenfeld, S ^a   Mantamadiotis, T ^b   Lemberger, T ^b   Greiner, E ^b   Stewart, A F ^a   Schtz, G ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

BAC; CamKII ; ET recombination; iCre recombinase; LoxP

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GENE PRODUCT; PROTEIN CAMKII ALPHA; RECOMBINASE; UNCLASSIFIED DRUG; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; CRE RECOMBINASE; INTEGRASE; PRIMER DNA; PROTEIN KINASE (CALCIUM,CALMODULIN); VIRUS PROTEIN;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BRAIN; BRAIN CORTEX; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; EXPRESSION VECTOR; GENE EXPRESSION REGULATION; GENE INACTIVATION; HIPPOCAMPUS; HYPOTHALAMUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; THALAMUS; TRANSGENIC MOUSE; ANIMAL; BACULOVIRUS; C57BL MOUSE; CHEMISTRY; CROSS BREEDING; ENZYME IMMUNOASSAY; ENZYMOLOGY; GENE SILENCING; GENE VECTOR; GENETICS; GROWTH, DEVELOPMENT AND AGING; IN SITU HYBRIDIZATION; METABOLISM; POLYMERASE CHAIN REACTION;

MUS MUSCULUS;

ANIMALS; BACULOVIRIDAE; BRAIN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CROSSES, GENETIC; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA PRIMERS; GENE SILENCING; GENETIC VECTORS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; INTEGRASES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; POLYMERASE CHAIN REACTION; VIRAL PROTEINS;

EID: 0034741267     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.1078     Document Type: Article

References (17)

1. Studies on the properties of P1 site-specific recombination: Evidence for topologically unlinked products following recombination
2. Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform
3. A simple assay to determine the functionality of Cre or FLP recombination targets in genomic manipulation constructs
4. CamKIIalpha-Cre transgene expression and recombination patterns in the mouse brain
5. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
6. Developmental profile of kainate receptor subunit KA1 revealed by Cre expression in YAC transgenic mice
7. Inducible site-specific recombination in the brain
8. Rapid modification of bacterial artificial chromosomes by ET- recombination
9. YAC transfer by microinjection
10. A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice
11. Comparative study of the distribution of calmodulin kinase II and calcineurin in the mouse brain
12. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
13. Subregion- and cell type-restricted gene knockout in mouse brain
14. In situ hybridization with oligonucleotides: A simplified method to detect Drosophila transcripts
15. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome
16. BAC-mediated gene-dosage analysis reveals a role for Ziprol (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin
17. A new logic for DNA engineering using recombination in Escherichia coli