메뉴 건너뛰기




Volumn 27, Issue , 2010, Pages 155-181

The role of 5-HT2C receptors in the antidepressant response: A critical review

Author keywords

[No Author keywords available]

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; 1 (3 TRIFLUOROMETHYLPHENYL)PIPERAZINE; 1,2,3,5 TETRAHYDRO 5 METHYL 1 (3 PYRIDYLCARBAMOYL)PYRROLO[2,3 F]INDOLE; 2 (6 CHLORO 5 FLUORO 1 INDOLYL) 1 METHYLETHYLAMINE; 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL] 6 TRIFLUOROMETHYLINDOLINE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; 8,9 DICHLORO 2,3,4,4A TETRAHYDRO 1H PYRAZINO[1,2 A]QUINOXALIN 5(6H) ONE; AGOMELATINE; AMITRIPTYLINE; AMOXAPINE; ANTIDEPRESSANT AGENT; CITALOPRAM; CLOMIPRAMINE; DESIPRAMINE; DOXEPIN; FLUOXETINE; FLUVOXAMINE; IMIPRAMINE; MAPROTILINE; MIANSERIN; MIRTAZAPINE; NEFAZODONE; NORADRENALIN UPTAKE INHIBITOR; NORTRIPTYLINE; S 32006; SEROTONIN 2C AGONIST; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; SEROTONIN UPTAKE INHIBITOR; SODIUM CHLORIDE; TRAZODONE; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; WAY 63909;

EID: 78649685750     PISSN: 16622685     EISSN: 16624505     Source Type: Book Series    
DOI: 10.1159/000319513     Document Type: Review
Times cited : (3)

References (157)
  • 2
    • 0345556939 scopus 로고
    • A unique serotonin receptor in choroid plexus is linked to phosphatidylinositol turnover
    • Conn PJ, Sanders-Bush E, Hoffman BJ, Hartig PR: A unique serotonin receptor in choroid plexus is linked to phosphatidylinositol turnover. Proc Natl Acad Sci USA 1986;83:4086-4088.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 4086-4088
    • Conn, P.J.1    Sanders-Bush, E.2    Hoffman, B.J.3    Hartig, P.R.4
  • 4
    • 0030612256 scopus 로고    scopus 로고
    • Distribution of the 5-hydroxytryptamine2C receptor protein in adult rat brain and spinal cord determined using a receptor-directed antibody: Effect of 5, 7-dihydroxytryptamine
    • Sharma A, Punhani T, Fone KC: Distribution of the 5-hydroxytryptamine2C receptor protein in adult rat brain and spinal cord determined using a receptor-directed antibody: effect of 5, 7-dihydroxytryptamine. Synapse 1997;27:45-56.
    • (1997) Synapse , vol.27 , pp. 45-56
    • Sharma, A.1    Punhani, T.2    Fone, K.C.3
  • 7
    • 0036141126 scopus 로고    scopus 로고
    • Serotonin 5-HT (2C) receptor knockout mice: Autoradiographic analysis of multiple serotonin receptors
    • Lopez-Gimenez JF, Tecott LH, Palacios JM, Mengod G, Vilaro MT: Serotonin 5-HT (2C) receptor knockout mice: autoradiographic analysis of multiple serotonin receptors. J Neurosci Res 2002;67:69-85.
    • (2002) J. Neurosci. Res. , vol.67 , pp. 69-85
    • Lopez-Gimenez, J.F.1    Tecott, L.H.2    Palacios, J.M.3    Mengod, G.4    Vilaro, M.T.5
  • 9
    • 33645230435 scopus 로고    scopus 로고
    • 2C receptors as a target for the treatment of depressive and anxious states: Focus on novel therapeutic strategies
    • 2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies. Therapie 2005;60:441-460.
    • (2005) Therapie , vol.60 , pp. 441-460
    • Millan, M.J.1
  • 10
  • 13
    • 33751192681 scopus 로고    scopus 로고
    • Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model
    • Bertaina-Anglade V, Drieu La Rochelle C, Boyer PA, Mocaer E: Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model. Behav Pharmacol 2006;17:703-713.
    • (2006) Behav. Pharmacol. , vol.17 , pp. 703-713
    • Bertaina-Anglade, V.1    La Rochelle, D.C.2    Boyer, P.A.3    Mocaer, E.4
  • 16
    • 0842329750 scopus 로고    scopus 로고
    • Modification of human 5-HT (2C) receptor function by Cys23Ser, an abundant, naturally occurring amino-acid substitution
    • Okada M, Northup JK, Ozaki N, Russell JT, Linnoila M, Goldman D: Modification of human 5-HT (2C) receptor function by Cys23Ser, an abundant, naturally occurring amino-acid substitution. Mol Psychiatry 2004;9:55-64.
    • (2004) Mol. Psychiatry , vol.9 , pp. 55-64
    • Okada, M.1    Northup, J.K.2    Ozaki, N.3    Russell, J.T.4    Linnoila, M.5    Goldman, D.6
  • 19
    • 0027393653 scopus 로고
    • Effects of repeated mild stress and two antidepressant treatments on the behavioral response to 5HT1C receptor activation in rats
    • Moreau JL, Jenck F, Martin JR, Perrin S, Haefely WE: Effects of repeated mild stress and two antidepressant treatments on the behavioral response to 5HT1C receptor activation in rats. Psychopharmacology (Berl) 1993;110:140-144.
    • (1993) Psychopharmacology (Berl) , vol.110 , pp. 140-144
    • Moreau, J.L.1    Jenck, F.2    Martin, J.R.3    Perrin, S.4    Haefely, W.E.5
  • 21
    • 11144343305 scopus 로고    scopus 로고
    • Hyperfunctionality of serotonin-2C receptor-mediated inhibition of accumbal dopamine release in an animal model of depression is reversed by antidepressant treatment
    • Dremencov E, Newman ME, Kinor N, Blatman-Jan G, Schindler CJ, Overstreet DH, Yadid G: Hyperfunctionality of serotonin-2C receptor-mediated inhibition of accumbal dopamine release in an animal model of depression is reversed by antidepressant treatment. Neuropharmacology 2005;48:34-42.
    • (2005) Neuropharmacology , vol.48 , pp. 34-42
    • Dremencov, E.1    Newman, M.E.2    Kinor, N.3    Blatman-Jan, G.4    Schindler, C.J.5    Overstreet, D.H.6    Yadid, G.7
  • 22
    • 63449140765 scopus 로고    scopus 로고
    • The effects of the selective 5-HT (2C) receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats
    • Strong PV, Greenwood BN, Fleshner M: The effects of the selective 5-HT (2C) receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats. Psychopharmacology (Berl) 2009;203:665-675.
    • (2009) Psychopharmacology (Berl) , vol.203 , pp. 665-675
    • Strong, P.V.1    Greenwood, B.N.2    Fleshner, M.3
  • 26
    • 0033681079 scopus 로고    scopus 로고
    • Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine (2C) receptors
    • Cryan JF, Lucki I: Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine (2C) receptors. J Pharmacol Exp Ther 2000;295:1120-1126.
    • (2000) J. Pharmacol. Exp. Ther. , vol.295 , pp. 1120-1126
    • Cryan, J.F.1    Lucki, I.2
  • 29
    • 0030050976 scopus 로고    scopus 로고
    • Comorbidity of DSM-III-R major depressive disorder in the general population: Results from the US national comorbidity survey
    • Kessler RC, Nelson CB, McGonagle KA, Liu J, Swartz M, Blazer DG: Comorbidity of DSM-III-R major depressive disorder in the general population: results from the US National Comorbidity Survey. Br J Psychiatry Suppl 1996;30:17-30.
    • (1996) Br. J. Psychiatry Suppl. , vol.30 , pp. 17-30
    • Kessler, R.C.1    Nelson, C.B.2    McGonagle, K.A.3    Liu, J.4    Swartz, M.5    Blazer, D.G.6
  • 30
    • 0027416876 scopus 로고
    • The neurobiological basis of mixed depression-anxiety states
    • Gulley LR, Nemeroff CB: The neurobiological basis of mixed depression-anxiety states. J Clin Psychiatry 1993;54(Suppl): 16-19.
    • (1993) J. Clin. Psychiatry , vol.54 , Issue.SUPPL. , pp. 16-19
    • Gulley, L.R.1    Nemeroff, C.B.2
  • 31
    • 0033369417 scopus 로고    scopus 로고
    • The functional anatomy, neurochemistry, and pharmacology of anxiety
    • Ninan PT: The functional anatomy, neurochemistry, and pharmacology of anxiety. J Clin Psychiatry 1999;60(Suppl 22):12-17.
    • (1999) J. Clin. Psychiatry , vol.60 , Issue.22 SUPPL. , pp. 12-17
    • Ninan, P.T.1
  • 32
    • 0023179757 scopus 로고
    • Serotonin function in anxiety. 2. Effects of the serotonin agonist MCPP in panic disorder patients and healthy subjects
    • Charney DS, Woods SW, Goodman WK, Heninger GR: Serotonin function in anxiety. 2. Effects of the serotonin agonist MCPP in panic disorder patients and healthy subjects. Psychopharmacology (Berl) 1987;92:14-24.
    • (1987) Psychopharmacology (Berl) , vol.92 , pp. 14-24
    • Charney, D.S.1    Woods, S.W.2    Goodman, W.K.3    Heninger, G.R.4
  • 34
    • 0023931304 scopus 로고
    • The jitteriness syndrome in panic disorder patients treated with antidepressants
    • Pohl R, Yeragani VK, Balon R, Lycaki H: The jitteriness syndrome in panic disorder patients treated with antidepressants. J Clin Psychiatry 1988;49:100-104.
    • (1988) J. Clin. Psychiatry , vol.49 , pp. 100-104
    • Pohl, R.1    Yeragani, V.K.2    Balon, R.3    Lycaki, H.4
  • 35
    • 0034117399 scopus 로고    scopus 로고
    • Evidence for accelerated desensitisation of 5-HT (2C) receptors following combined treatment with fluoxetine and the 5-HT (1A) receptor antagonist, WAY 100, 635, in the rat
    • Bristow LJ, O'Connor D, Watts R, Duxon MS, Hutson PH: Evidence for accelerated desensitisation of 5-HT (2C) receptors following combined treatment with fluoxetine and the 5-HT (1A) receptor antagonist, WAY 100, 635, in the rat. Neuropharmacology 2000;39:1222-1236.
    • (2000) Neuropharmacology , vol.39 , pp. 1222-1236
    • Bristow, L.J.1    O'Connor, D.2    Watts, R.3    Duxon, M.S.4    Hutson, P.H.5
  • 37
    • 78649683879 scopus 로고    scopus 로고
    • 5-HT (2c) receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: Modulation by chronic paroxetine treatment
    • Jul. 29 Epub ahead of print
    • Mongeau R, Martin C, Chevarin C, Maldonado R, Hamon M, Robledo P, Lanfumey L: 5-HT (2c) receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: modulation by chronic paroxetine treatment. J Neurochem 2010 Jul. 29 [Epub ahead of print].
    • (2010) J. Neurochem.
    • Mongeau, R.1    Martin, C.2    Chevarin, C.3    Maldonado, R.4    Hamon, M.5    Robledo, P.6    Lanfumey, L.7
  • 38
    • 0027056458 scopus 로고
    • Anxiogenic-like effects of fluprazine and eltoprazine in the mouse elevated plusmaze: Profile comparisons with 8-OH-DPAT, CGS 12066B, TFMPP and mCPP
    • Rodgers RJ, Cole JC, Cobain MR, Daly P, Doran PJ, Eells JR, Wallis P: Anxiogenic-like effects of fluprazine and eltoprazine in the mouse elevated plusmaze: profile comparisons with 8-OH-DPAT, CGS 12066B, TFMPP and mCPP. Behav Pharmacol 1992;3:621-634.
    • (1992) Behav. Pharmacol. , vol.3 , pp. 621-634
    • Rodgers, R.J.1    Cole, J.C.2    Cobain, M.R.3    Daly, P.4    Doran, P.J.5    Eells, J.R.6    Wallis, P.7
  • 39
    • 0027336909 scopus 로고
    • Sensitization to 5-HT1C receptor agonist in rats observed following withdrawal from chronic ethanol
    • Rezazadeh SM, Prather PL, Lal H: Sensitization to 5-HT1C receptor agonist in rats observed following withdrawal from chronic ethanol. Alcohol 1993;10:281-283.
    • (1993) Alcohol. , vol.10 , pp. 281-283
    • Rezazadeh, S.M.1    Prather, P.L.2    Lal, H.3
  • 41
    • 0028050011 scopus 로고
    • Dissociation of serotonergic regulation of anxiety and ethanol self-administration: A study with mCPP
    • Buczek Y, Tomkins DM, Higgins GA, Sellers EM: Dissociation of serotonergic regulation of anxiety and ethanol self-administration: a study with mCPP. Behav Pharmacol 1994;5:470-484.
    • (1994) Behav. Pharmacol. , vol.5 , pp. 470-484
    • Buczek, Y.1    Tomkins, D.M.2    Higgins, G.A.3    Sellers, E.M.4
  • 42
    • 0028075302 scopus 로고
    • Behavioural and pharmacological characterisation of the elevated 'zero-maze' as an animal model of anxiety
    • Shepherd JK, Grewal SS, Fletcher A, Bill DJ, Dourish CT: Behavioural and pharmacological characterisation of the elevated 'zero-maze' as an animal model of anxiety. Psychopharmacology (Berl) 1994;116:56-64.
    • (1994) Psychopharmacology (Berl) , vol.116 , pp. 56-64
    • Shepherd, J.K.1    Grewal, S.S.2    Fletcher, A.3    Bill, D.J.4    Dourish, C.T.5
  • 43
    • 0027993130 scopus 로고
    • Evidence that tolerance to the anxiogenic-like effects of mCPP does not involve alteration in the function of 5-HT (2C) receptors in the rat choroid plexus
    • Griebel G, Moreau JL, Jenck F, Mutel V, Martin JR, Misslin R: Evidence that tolerance to the anxiogenic-like effects of mCPP does not involve alteration in the function of 5-HT (2C) receptors in the rat choroid plexus. Behav Pharmacol 1994;5:642-645.
    • (1994) Behav. Pharmacol. , vol.5 , pp. 642-645
    • Griebel, G.1    Moreau, J.L.2    Jenck, F.3    Mutel, V.4    Martin, J.R.5    Misslin, R.6
  • 44
    • 0029964263 scopus 로고    scopus 로고
    • Dissociation of effects of chronic diazepam treatment and withdrawal on hippocampal dialysate 5-HT and mCPP-induced anxiety in rats
    • Gibson EL, Barnfield AM, Curzon G: Dissociation of effects of chronic diazepam treatment and withdrawal on hippocampal dialysate 5-HT and mCPP-induced anxiety in rats. Behav Pharmacol 1996;7:185-193.
    • (1996) Behav. Pharmacol. , vol.7 , pp. 185-193
    • Gibson, E.L.1    Barnfield, A.M.2    Curzon, G.3
  • 45
    • 0037366752 scopus 로고    scopus 로고
    • Wistar-Kyoto rats are sensitive to the hypolocomotor and anxiogenic effects of mCPP
    • Durand M, Mormede P, Chaouloff F: Wistar-Kyoto rats are sensitive to the hypolocomotor and anxiogenic effects of mCPP. Behav Pharmacol 2003;14:173-177.
    • (2003) Behav. Pharmacol. , vol.14 , pp. 173-177
    • Durand, M.1    Mormede, P.2    Chaouloff, F.3
  • 46
    • 20044369405 scopus 로고    scopus 로고
    • The use of sudden darkness in mice: A behavioural and pharmacological approach
    • Bert B, Felicio LF, Fink H, Nasello AG: The use of sudden darkness in mice: a behavioural and pharmacological approach. Psychopharmacology (Berl) 2005;179:846-853.
    • (2005) Psychopharmacology (Berl) , vol.179 , pp. 846-853
    • Bert, B.1    Felicio, L.F.2    Fink, H.3    Nasello, A.G.4
  • 47
    • 0037452851 scopus 로고    scopus 로고
    • Anxiolytic-like effects of 5-HT2 ligands on three mouse models of anxiety
    • Nic Dhonnchadha BA, Bourin M, Hascoet M: Anxiolytic-like effects of 5-HT2 ligands on three mouse models of anxiety. Behav Brain Res 2003;140:203-214.
    • (2003) Behav. Brain Res. , vol.140 , pp. 203-214
    • Dhonnchadha, B.A.N.1    Bourin, M.2    Hascoet, M.3
  • 48
    • 26844499950 scopus 로고    scopus 로고
    • Behavioral effects of systemically administered MK-212 are prevented by ritanserin microinfusion into the basolateral amygdala of rats exposed to the elevated plus-maze
    • Mello Cruz AP, Pinheiro G, Alves SH, Ferreira G, Mendes M, Faria L, Macedo CE, Motta V, Landeira-Fernandez J: Behavioral effects of systemically administered MK-212 are prevented by ritanserin microinfusion into the basolateral amygdala of rats exposed to the elevated plus-maze. Psycho pharmacology (Berl) 2005;182:345-354.
    • (2005) Psycho Pharmacology (Berl) , vol.182 , pp. 345-354
    • Cruz, A.P.M.1    Pinheiro, G.2    Alves, S.H.3    Ferreira, G.4    Mendes, M.5    Faria, L.6    Macedo, C.E.7    Motta, V.8    Landeira-Fernandez, J.9
  • 49
    • 33846937581 scopus 로고    scopus 로고
    • Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze
    • Cornelio AM, Nunes-de-Souza RL: Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze. Behav Brain Res 2007;178:82-89.
    • (2007) Behav. Brain Res. , vol.178 , pp. 82-89
    • Cornelio, A.M.1    Nunes-de-Souza, R.L.2
  • 50
    • 69349102403 scopus 로고    scopus 로고
    • 1A) receptors located within the periaqueductal gray in the elevated plus-maze test-retest paradigm in mice
    • 1A) receptors located within the periaqueductal gray in the elevated plus-maze test-retest paradigm in mice. Prog Neuropsychopharmacol Biol Psychiatry 2009;33:1261-1269.
    • (2009) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.33 , pp. 1261-1269
    • Gomes, K.S.1    Nunes-de-Souza, R.L.2
  • 52
    • 3042549948 scopus 로고    scopus 로고
    • Serotonin, the periaqueductal gray and panic
    • Graeff FG: Serotonin, the periaqueductal gray and panic. Neurosci Biobehav Rev 2004;28:239-259.
    • (2004) Neurosci. Biobehav. Rev. , vol.28 , pp. 239-259
    • Graeff, F.G.1
  • 53
    • 0344959633 scopus 로고    scopus 로고
    • Anxiolytic effect of intra-amygdala injection of midazolam and 8-hydroxy-2-(di-n-propylamino) tetralin in the elevated T-maze
    • Zangrossi H Jr, Viana MB, Graeff FG: Anxiolytic effect of intra-amygdala injection of midazolam and 8-hydroxy-2-(di-n-propylamino) tetralin in the elevated T-maze. Eur J Pharmacol 1999;369:267-270.
    • (1999) Eur. J. Pharmacol. , vol.369 , pp. 267-270
    • Zangrossi Jr., H.1    Viana, M.B.2    Graeff, F.G.3
  • 54
    • 19944380200 scopus 로고    scopus 로고
    • The tail suspension test as a model for assessing antidepressant activity: Review of pharmacological and genetic studies in mice
    • Cryan JF, Mombereau C, Vassout A: The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci Biobehav Rev 2005;29:571-625.
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , pp. 571-625
    • Cryan, J.F.1    Mombereau, C.2    Vassout, A.3
  • 55
    • 0035061746 scopus 로고    scopus 로고
    • Involvement of 5-HT (2C) receptors in the anti-immobility effects of antidepressants in the forced swimming test in mice
    • Clenet F, De Vos A, Bourin M: Involvement of 5-HT (2C) receptors in the anti-immobility effects of antidepressants in the forced swimming test in mice. Eur Neuropsychopharmacol 2001;11:145-152.
    • (2001) Eur. Neuropsychopharmacol. , vol.11 , pp. 145-152
    • Clenet, F.1    De Vos, A.2    Bourin, M.3
  • 57
    • 0030604052 scopus 로고    scopus 로고
    • Serotonin function in panic disorder: Intravenous administration of meta-chlorophenylpiperazine
    • Wetzler S, Asnis GM, DeLecuona JM, Kalus O: Serotonin function in panic disorder: intravenous administration of meta-chlorophenylpiperazine. Psychiatry Res 1996;64:77-82.
    • (1996) Psychiatry Res. , vol.64 , pp. 77-82
    • Wetzler, S.1    Asnis, G.M.2    DeLecuona, J.M.3    Kalus, O.4
  • 59
    • 0023190378 scopus 로고
    • Synaptic interaction of serotonergic axons and corticotropin releasing factor (CRF) synthesizing neurons in the hypothalamic paraventricular nucleus of the rat. A light and electron microscopic immunocytochemical study
    • Liposits Z, Phelix C, Paull WK: Synaptic interaction of serotonergic axons and corticotropin releasing factor (CRF) synthesizing neurons in the hypothalamic paraventricular nucleus of the rat. A light and electron microscopic immunocytochemical study. Histochemistry 1987;86:541-549.
    • (1987) Histochemistry , vol.86 , pp. 541-549
    • Liposits, Z.1    Phelix, C.2    Paull, W.K.3
  • 60
    • 0030250987 scopus 로고    scopus 로고
    • The 5-HT1A receptor is not involved in emotional stressinduced rises in stress hormones
    • Groenink L, Mos J, van der Gugten J, Olivier B: The 5-HT1A receptor is not involved in emotional stressinduced rises in stress hormones. Pharmacol Biochem Behav 1996;55:303-308.
    • (1996) Pharmacol. Biochem. Behav. , vol.55 , pp. 303-308
    • Groenink, L.1    Mos, J.2    Van Der Gugten, J.3    Olivier, B.4
  • 63
    • 2642582531 scopus 로고    scopus 로고
    • Differential expression of 5HT-1A, alpha 1b adrenergic, CRF-R1, and CRF-R2 receptor mRNA in serotonergic, gamma-aminobutyric acidergic, and catecholaminergic cells of the rat dorsal raphe nucleus
    • Day HE, Greenwood BN, Hammack SE, Watkins LR, Fleshner M, Maier SF, Campeau S: Differential expression of 5HT-1A, alpha 1b adrenergic, CRF-R1, and CRF-R2 receptor mRNA in serotonergic, gamma-aminobutyric acidergic, and catecholaminergic cells of the rat dorsal raphe nucleus. J Comp Neurol 2004;474:364-378.
    • (2004) J. Comp. Neurol. , vol.474 , pp. 364-378
    • Day, H.E.1    Greenwood, B.N.2    Hammack, S.E.3    Watkins, L.R.4    Fleshner, M.5    Maier, S.F.6    Campeau, S.7
  • 64
    • 0027384908 scopus 로고
    • Evidence that corticotropin-releasing factor within the extended amygdala mediates the activation of tryptophan hydroxylase produced by sound stress in the rat
    • Boadle-Biber MC, Singh VB, Corley KC, Phan TH, Dilts RP: Evidence that corticotropin-releasing factor within the extended amygdala mediates the activation of tryptophan hydroxylase produced by sound stress in the rat. Brain Res 1993;628:105-114.
    • (1993) Brain Res. , vol.628 , pp. 105-114
    • Boadle-Biber, M.C.1    Singh, V.B.2    Corley, K.C.3    Phan, T.H.4    Dilts, R.P.5
  • 65
    • 41449096422 scopus 로고    scopus 로고
    • Activation of raphe efferents to the medial prefrontal cortex by corticotropin-releasing factor: Correlation with anxiety-like behavior
    • Meloni EG, Reedy CL, Cohen BM, Carlezon WA Jr: Activation of raphe efferents to the medial prefrontal cortex by corticotropin-releasing factor: correlation with anxiety-like behavior. Biol Psychiatry 2008;63:832-839.
    • (2008) Biol. Psychiatry , vol.63 , pp. 832-839
    • Meloni, E.G.1    Reedy, C.L.2    Cohen, B.M.3    Carlezon Jr., W.A.4
  • 66
    • 44549083056 scopus 로고    scopus 로고
    • Restraint stress increases serotonin release in the central nucleus of the amygdala via activation of corticotropin-releasing factor receptors
    • Mo B, Feng N, Renner K, Forster G: Restraint stress increases serotonin release in the central nucleus of the amygdala via activation of corticotropin-releasing factor receptors. Brain Res Bull 2008;76:493-498.
    • (2008) Brain Res. Bull. , vol.76 , pp. 493-498
    • Mo, B.1    Feng, N.2    Renner, K.3    Forster, G.4
  • 67
    • 0034604778 scopus 로고    scopus 로고
    • Serotonin 5-HT2 receptors activate local GABA inhibitory inputs to serotonergic neurons of the dorsal raphe nucleus
    • Liu R, Jolas T, Aghajanian G: Serotonin 5-HT2 receptors activate local GABA inhibitory inputs to serotonergic neurons of the dorsal raphe nucleus. Brain Res 2000;873:34-55.
    • (2000) Brain Res. , vol.873 , pp. 34-55
    • Liu, R.1    Jolas, T.2    Aghajanian, G.3
  • 68
    • 21344449283 scopus 로고    scopus 로고
    • A role for midbrain raphe gamma aminobutyric acid neurons in 5-hydroxytryptamine feedback control
    • Boothman LJ, Sharp T: A role for midbrain raphe gamma aminobutyric acid neurons in 5-hydroxytryptamine feedback control. Neuroreport 2005;16:891-896.
    • (2005) Neuroreport , vol.16 , pp. 891-896
    • Boothman, L.J.1    Sharp, T.2
  • 70
    • 33845231964 scopus 로고    scopus 로고
    • In vivo evidence that 5-HT (2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanism
    • Boothman L, Raley J, Denk F, Hirani E, Sharp T: In vivo evidence that 5-HT (2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanism. Br J Pharmacol 2006;149:861-869.
    • (2006) Br. J. Pharmacol. , vol.149 , pp. 861-869
    • Boothman, L.1    Raley, J.2    Denk, F.3    Hirani, E.4    Sharp, T.5
  • 71
    • 0038298457 scopus 로고    scopus 로고
    • 2A and 5-HT2B/C receptors regulate 5-HT cell firing in the dorsal raphe nucleus of the anaesthetised rat
    • 2A and 5-HT2B/C receptors regulate 5-HT cell firing in the dorsal raphe nucleus of the anaesthetised rat. Br J Pharmacol 2003;139:998-1004.
    • (2003) Br. J. Pharmacol. , vol.139 , pp. 998-1004
    • Boothman, L.J.1    Allers, K.A.2    Rasmussen, K.3    Sharp, T.4
  • 72
    • 0025237692 scopus 로고
    • Effects of a selective 5-HT2 agonist, DOI, on 5-HT neuronal firing in the dorsal raphe nucleus and 5-HT release and metabolism in the frontal cortex
    • Wright IK, Garratt JC, Marsden CA: Effects of a selective 5-HT2 agonist, DOI, on 5-HT neuronal firing in the dorsal raphe nucleus and 5-HT release and metabolism in the frontal cortex. Br J Pharmacol 1990;99:221-222.
    • (1990) Br. J. Pharmacol. , vol.99 , pp. 221-222
    • Wright, I.K.1    Garratt, J.C.2    Marsden, C.A.3
  • 73
    • 70350547582 scopus 로고    scopus 로고
    • Further pharmacological characterization of 5-HT (2C) receptor agonistinduced inhibition of 5-HT neuronal activity in the dorsal raphe nucleus in vivo
    • Queree P, Peters S, Sharp T: Further pharmacological characterization of 5-HT (2C) receptor agonistinduced inhibition of 5-HT neuronal activity in the dorsal raphe nucleus in vivo. Br J Pharmacol 2009;158:1477-1485.
    • (2009) Br. J. Pharmacol. , vol.158 , pp. 1477-1485
    • Queree, P.1    Peters, S.2    Sharp, T.3
  • 74
    • 0034213062 scopus 로고    scopus 로고
    • Serotonin (2C) receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: A combined dialysis and electrophysiological analysis in the rat
    • Gobert A, Rivet JM, Lejeune F, Newman-Tancredi A, Adhumeau-Auclair A, Nicolas J P, Cistarelli L, Melon C, Millan MJ: Serotonin (2C) receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: a combined dialysis and electrophysiological analysis in the rat. Synapse 2000;36:205-221.
    • (2000) Synapse , vol.36 , pp. 205-221
    • Gobert, A.1    Rivet, J.M.2    Lejeune, F.3    Newman-Tancredi, A.4    Adhumeau-Auclair, A.5    Nicolas, J.P.6    Cistarelli, L.7    Melon, C.8    Millan, M.J.9
  • 75
    • 0031863323 scopus 로고    scopus 로고
    • Effect of antipsychotic drugs on extracellular serotonin levels in rat medial prefrontal cortex and nucleus accumbens
    • Ichikawa J, Kuroki T, Dai J, Meltzer HY: Effect of antipsychotic drugs on extracellular serotonin levels in rat medial prefrontal cortex and nucleus accumbens. Eur J Pharmacol 1998;351:163-171.
    • (1998) Eur. J. Pharmacol. , vol.351 , pp. 163-171
    • Ichikawa, J.1    Kuroki, T.2    Dai, J.3    Meltzer, H.Y.4
  • 76
    • 0033008804 scopus 로고    scopus 로고
    • Serotonin (5-HT) 2A receptor activation enhances dialysate levels of dopamine and noradrenaline, but not 5-HT, in the frontal cortex of freely-moving rats
    • Gobert A, Millan MJ: Serotonin (5-HT) 2A receptor activation enhances dialysate levels of dopamine and noradrenaline, but not 5-HT, in the frontal cortex of freely-moving rats. Neuropharmacology 1999;38:315-317.
    • (1999) Neuropharmacology , vol.38 , pp. 315-317
    • Gobert, A.1    Millan, M.J.2
  • 77
    • 33645984870 scopus 로고    scopus 로고
    • Investigation of the SSRI augmentation properties of 5-HT (2) receptor antagonists using in vivo microdialysis
    • Boothman LJ, Mitchell SN, Sharp T: Investigation of the SSRI augmentation properties of 5-HT (2) receptor antagonists using in vivo microdialysis. Neuropharmacology 2006;50:726-732.
    • (2006) Neuropharmacology , vol.50 , pp. 726-732
    • Boothman, L.J.1    Mitchell, S.N.2    Sharp, T.3
  • 78
    • 27844601627 scopus 로고    scopus 로고
    • 2A receptor antagonist M100907 enhances antidepressant-like behavioral effects of the SSRI fluoxetine
    • 2A receptor antagonist M100907 enhances antidepressant-like behavioral effects of the SSRI fluoxetine. Neuropsychopharmacology 2005;30:2205-2215.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 2205-2215
    • Marek, G.J.1    Martin-Ruiz, R.2    Abo, A.3    Artigas, F.4
  • 80
    • 0036720639 scopus 로고    scopus 로고
    • Rapid desensitization of the serotonin (2C) receptor system: Effector pathway and agonist dependence
    • Stout BD, Clarke WP, Berg KA: Rapid desensitization of the serotonin (2C) receptor system: effector pathway and agonist dependence. J Pharmacol Exp Ther 2002;302:957-962.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 957-962
    • Stout, B.D.1    Clarke, W.P.2    Berg, K.A.3
  • 81
    • 0029117884 scopus 로고
    • Increased basal phosphorylation of the constitutively active serotonin 2C receptor accompanies agonist-mediated desensitization
    • Westphal RS, Backstrom JR, Sanders-Bush E: Increased basal phosphorylation of the constitutively active serotonin 2C receptor accompanies agonist-mediated desensitization. Mol Pharmacol 1995;48:200-205.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 200-205
    • Westphal, R.S.1    Backstrom, J.R.2    Sanders-Bush, E.3
  • 82
    • 0034604706 scopus 로고    scopus 로고
    • 2C receptor PDZ recognition motif prevents receptor phosphorylation and delays resensitization of receptor responses
    • 2C receptor PDZ recognition motif prevents receptor phosphorylation and delays resensitization of receptor responses. J Biol Chem 2000;275:23620-23626.
    • (2000) J. Biol. Chem. , vol.275 , pp. 23620-23626
    • Backstrom, J.R.1    Price, R.D.2    Reasoner, D.T.3    Sanders-Bush, E.4
  • 83
    • 33750501125 scopus 로고    scopus 로고
    • Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability
    • Gavarini S, Becamel C, Altier C, Lory P, Poncet J, Wijnholds J, Bockaert J, Marin P: Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability. Mol Biol Cell 2006;17:4619-4631.
    • (2006) Mol. Biol. Cell. , vol.17 , pp. 4619-4631
    • Gavarini, S.1    Becamel, C.2    Altier, C.3    Lory, P.4    Poncet, J.5    Wijnholds, J.6    Bockaert, J.7    Marin, P.8
  • 84
    • 4243191447 scopus 로고    scopus 로고
    • Ligand dependency of 5-hydroxytryptamine 2C receptor internalization
    • Schlag BD, Lou Z, Fennell M, Dunlop J: Ligand dependency of 5-hydroxytryptamine 2C receptor internalization. J Pharmacol Exp Ther 2004;310:865-870.
    • (2004) J. Pharmacol. Exp. Ther. , vol.310 , pp. 865-870
    • Schlag, B.D.1    Lou, Z.2    Fennell, M.3    Dunlop, J.4
  • 86
    • 0029045445 scopus 로고
    • Serotonergic antagonists differentially inhibit spontaneous activity and decrease ligand binding capacity of the rat 5-hydroxytryptamine type 2C receptor in Sf9 cells
    • Labrecque J, Fargin A, Bouvier M, Chidiac P, Dennis M: Serotonergic antagonists differentially inhibit spontaneous activity and decrease ligand binding capacity of the rat 5-hydroxytryptamine type 2C receptor in Sf9 cells. Mol Pharmacol 1995;48:150-159.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 150-159
    • Labrecque, J.1    Fargin, A.2    Bouvier, M.3    Chidiac, P.4    Dennis, M.5
  • 87
    • 0028180127 scopus 로고
    • Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands
    • Barker EL, Westphal RS, Schmidt D, Sanders-Bush E: Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands. J Biol Chem 1994;269:11687-11690.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11687-11690
    • Barker, E.L.1    Westphal, R.S.2    Schmidt, D.3    Sanders-Bush, E.4
  • 89
    • 40849137938 scopus 로고    scopus 로고
    • Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: Differential modulation of cell surface expression and signal transduction
    • Chanrion B, Mannoury La Cour C, Gavarini S, Seimandi M, Vincent L, Pujol JF, Bockaert J, Marin P, Millan MJ: Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction. Mol Pharmacol 2008;73:748-757.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 748-757
    • Chanrion, B.1    La Cour, M.C.2    Gavarini, S.3    Seimandi, M.4    Vincent, L.5    Pujol, J.F.6    Bockaert, J.7    Marin, P.8    Millan, M.J.9
  • 94
    • 0019122846 scopus 로고
    • Long-term antidepressant treatment decreases spiroperidol-labeled serotonin receptor binding
    • Peroutka SJ, Snyder SH: Long-term antidepressant treatment decreases spiroperidol-labeled serotonin receptor binding. Science 1980;210:88-90.
    • (1980) Science , vol.210 , pp. 88-90
    • Peroutka, S.J.1    Snyder, S.H.2
  • 98
    • 0028783676 scopus 로고
    • 2C receptors after chronic treatment with clozapine, chlorpromazine and three putative atypical antipsychotic drugs
    • 2C receptors after chronic treatment with clozapine, chlorpromazine and three putative atypical antipsychotic drugs. Neuropsychopharmacology 1995;13:139-150.
    • (1995) Neuropsychopharmacology , vol.13 , pp. 139-150
    • Kuoppamaki, M.1    Palvimaki, E.P.2    Hietala, J.3    Syvalahti, E.4
  • 100
    • 0035664328 scopus 로고    scopus 로고
    • M-CPP hypolocomotion is selectively antagonized by compounds with high affinity for 5-HT (2C) receptors but not 5-HT (2A) or 5-HT (2B) receptors
    • Gleason SD, Lucaites VL, Shannon HE, Nelson DL, Leander JD: m-CPP hypolocomotion is selectively antagonized by compounds with high affinity for 5-HT (2C) receptors but not 5-HT (2A) or 5-HT (2B) receptors. Behav Pharmacol 2001;12:613-620.
    • (2001) Behav. Pharmacol. , vol.12 , pp. 613-620
    • Gleason, S.D.1    Lucaites, V.L.2    Shannon, H.E.3    Nelson, D.L.4    Leander, J.D.5
  • 102
    • 67650680328 scopus 로고    scopus 로고
    • Characterizing the effects of 5-HT (2C) receptor ligands on motor activity and feeding behaviour in 5-HT (2C) receptor knockout mice
    • Fletcher PJ, Tampakeras M, Sinyard J, Slassi A, Isaac M, Higgins GA: Characterizing the effects of 5-HT (2C) receptor ligands on motor activity and feeding behaviour in 5-HT (2C) receptor knockout mice. Neuropharmacology 2009;57:259-267.
    • (2009) Neuropharmacology , vol.57 , pp. 259-267
    • Fletcher, P.J.1    Tampakeras, M.2    Sinyard, J.3    Slassi, A.4    Isaac, M.5    Higgins, G.A.6
  • 104
    • 0034654893 scopus 로고    scopus 로고
    • A paradoxical locomotor response in serotonin 5-HT (2C) receptor mutant mice
    • Heisler LK, Tecott LH: A paradoxical locomotor response in serotonin 5-HT (2C) receptor mutant mice. J Neurosci 2000;20: RC71.
    • (2000) J. Neurosci. , vol.20
    • Heisler, L.K.1    Tecott, L.H.2
  • 107
    • 0028944999 scopus 로고
    • 2C receptor-mediated corticosterone and prolactin but not oxytocin and penile erection responses
    • 2C receptor-mediated corticosterone and prolactin but not oxytocin and penile erection responses. Eur J Pharmacol 1995;275:301-305.
    • (1995) Eur. J. Pharmacol. , vol.275 , pp. 301-305
    • Bagdy, G.1    Makara, G.B.2
  • 108
    • 47549092541 scopus 로고    scopus 로고
    • 5-HT (2C) receptor activation is a common mechanism on proerectile effects of apomorphine, oxytocin and melanotan-II in rats
    • Kimura Y, Naitou Y, Wanibuchi F, Yamaguchi T: 5-HT (2C) receptor activation is a common mechanism on proerectile effects of apomorphine, oxytocin and melanotan-II in rats. Eur J Pharmacol 2008;589:157-162.
    • (2008) Eur. J. Pharmacol. , vol.589 , pp. 157-162
    • Kimura, Y.1    Naitou, Y.2    Wanibuchi, F.3    Yamaguchi, T.4
  • 109
    • 0025918666 scopus 로고
    • 1C receptor mediated behaviour in rats following chronic treatment with 5-HT receptor agonists, antagonists or antidepressants
    • 1C receptor mediated behaviour in rats following chronic treatment with 5-HT receptor agonists, antagonists or antidepressants. Psychopharmacology (Berl) 1991;105:219-224.
    • (1991) Psychopharmacology (Berl) , vol.105 , pp. 219-224
    • Berendsen, H.H.1    Broekkamp, C.L.2
  • 110
    • 0030770172 scopus 로고    scopus 로고
    • The olfactory bulbectomized rat as a model of depression: An update
    • Kelly J P, Wrynn AS, Leonard BE: The olfactory bulbectomized rat as a model of depression: an update. Pharmacol Ther 1997;74:299-316.
    • (1997) Pharmacol. Ther. , vol.74 , pp. 299-316
    • Kelly, J.P.1    Wrynn, A.S.2    Leonard, B.E.3
  • 112
    • 0025095142 scopus 로고
    • Anxiogenic-like effect of infusing 1-(3-chlorophenyl) piperazine (mCPP) into the hippocampus
    • Whitton P, Curzon G: Anxiogenic-like effect of infusing 1-(3-chlorophenyl) piperazine (mCPP) into the hippocampus. Psychopharmacology (Berl) 1990;100:138-140.
    • (1990) Psychopharmacology (Berl) , vol.100 , pp. 138-140
    • Whitton, P.1    Curzon, G.2
  • 115
    • 59949089545 scopus 로고    scopus 로고
    • An immunocapture/scintillation proximity analysis of G alpha q/11 activation by native serotonin (5-HT) 2A receptors in rat cortex: Blockade by clozapine and mirtazapine
    • Mannoury LC, Chaput C, Touzard M, Millan MJ: An immunocapture/ scintillation proximity analysis of G alpha q/11 activation by native serotonin (5-HT) 2A receptors in rat cortex: blockade by clozapine and mirtazapine. Synapse 2009;63:95-105.
    • (2009) Synapse , vol.63 , pp. 95-105
    • Mannoury, L.C.1    Chaput, C.2    Touzard, M.3    Millan, M.J.4
  • 116
    • 1542330242 scopus 로고    scopus 로고
    • Relationship between anorexia and loss of serotonin uptake sites in brain of mice and rats receiving d-norfenfluramine or d-fenfluramine
    • Rowland NE, Rokadia S, Green DJ, Robertson K: Relationship between anorexia and loss of serotonin uptake sites in brain of mice and rats receiving d-norfenfluramine or d-fenfluramine. Pharmacol Biochem Behav 2004;77:541-546.
    • (2004) Pharmacol. Biochem. Behav. , vol.77 , pp. 541-546
    • Rowland, N.E.1    Rokadia, S.2    Green, D.J.3    Robertson, K.4
  • 117
    • 0037308664 scopus 로고    scopus 로고
    • Effect of repeated administration of dexfenfluramine on feeding and brain Fos in mice
    • Rowland NE, Robertson K, Green DJ: Effect of repeated administration of dexfenfluramine on feeding and brain Fos in mice. Physiol Behav 2003;78:295-301.
    • (2003) Physiol. Behav. , vol.78 , pp. 295-301
    • Rowland, N.E.1    Robertson, K.2    Green, D.J.3
  • 118
    • 0028067088 scopus 로고
    • Induction and habituation of immediate early gene expression in rat brain by acute and repeated restraint stress
    • Melia KR, Ryabinin AE, Schroeder R, Bloom FE, Wilson MC: Induction and habituation of immediate early gene expression in rat brain by acute and repeated restraint stress. J Neurosci 1994;14:5929-5938.
    • (1994) J. Neurosci. , vol.14 , pp. 5929-5938
    • Melia, K.R.1    Ryabinin, A.E.2    Schroeder, R.3    Bloom, F.E.4    Wilson, M.C.5
  • 119
    • 36949016219 scopus 로고    scopus 로고
    • Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: An in vivo microdialysis study with cocaine
    • Navailles S, Moison D, Cunningham KA, Spampinato U: Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine. Neuropsychopharmacology 2008;33:237-246.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 237-246
    • Navailles, S.1    Moison, D.2    Cunningham, K.A.3    Spampinato, U.4
  • 120
    • 67749111764 scopus 로고    scopus 로고
    • Effects of sustained serotonin reuptake inhibition on the firing of dopamine neurons in the rat ventral tegmental area
    • Dremencov E, El Mansari M, Blier P: Effects of sustained serotonin reuptake inhibition on the firing of dopamine neurons in the rat ventral tegmental area. J Psychiatry Neurosci 2009;34:223-229.
    • (2009) J. Psychiatry Neurosci. , vol.34 , pp. 223-229
    • Dremencov, E.1    El Mansari, M.2    Blier, P.3
  • 123
    • 0037171846 scopus 로고    scopus 로고
    • Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims
    • Gurevich I, Tamir H, Arango V, Dwork AJ, Mann JJ, Schmauss C: Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims. Neuron 2002;34:349-356.
    • (2002) Neuron , vol.34 , pp. 349-356
    • Gurevich, I.1    Tamir, H.2    Arango, V.3    Dwork, A.J.4    Mann, J.J.5    Schmauss, C.6
  • 125
    • 0038645126 scopus 로고    scopus 로고
    • RNA editing of serotonin 2C receptor in human postmortem brains of major mental disorders
    • Iwamoto K, Kato T: RNA editing of serotonin 2C receptor in human postmortem brains of major mental disorders. Neurosci Lett 2003;346:169-172.
    • (2003) Neurosci. Lett. , vol.346 , pp. 169-172
    • Iwamoto, K.1    Kato, T.2
  • 126
    • 0037114951 scopus 로고    scopus 로고
    • Modulation of serotonin 2C receptor editing by sustained changes in serotonergic neurotransmission
    • Gurevich I, Englander MT, Adlersberg M, Siegal NB, Schmauss C: Modulation of serotonin 2C receptor editing by sustained changes in serotonergic neurotransmission. J Neurosci 2002;22:10529-10532.
    • (2002) J. Neurosci. , vol.22 , pp. 10529-10532
    • Gurevich, I.1    Englander, M.T.2    Adlersberg, M.3    Siegal, N.B.4    Schmauss, C.5
  • 127
    • 12744273085 scopus 로고    scopus 로고
    • How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing
    • Englander MT, Dulawa SC, Bhansali P, Schmauss C: How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing. J Neurosci 2005;25:648-651.
    • (2005) J. Neurosci. , vol.25 , pp. 648-651
    • Englander, M.T.1    Dulawa, S.C.2    Bhansali, P.3    Schmauss, C.4
  • 132
    • 0028036898 scopus 로고
    • Neuroendocrine and behavioral responses to intravenous m-chlorophenylpiperazine (mCPP) in depressed patients and healthy comparison subjects
    • Anand A, Charney DS, Delgado PL, McDougle CJ, Heninger GR, Price LH: Neuroendocrine and behavioral responses to intravenous m-chlorophenylpiperazine (mCPP) in depressed patients and healthy comparison subjects. Am J Psychiatry 1994;151:1626-1630.
    • (1994) Am. J. Psychiatry , vol.151 , pp. 1626-1630
    • Anand, A.1    Charney, D.S.2    Delgado, P.L.3    McDougle, C.J.4    Heninger, G.R.5    Price, L.H.6
  • 133
    • 1642285042 scopus 로고    scopus 로고
    • Contributions of 5-HT (2C) receptors to multiple actions of central serotonin systems
    • Giorgetti M, Tecott LH: Contributions of 5-HT (2C) receptors to multiple actions of central serotonin systems. Eur J Pharmacol 2004;488:1-9.
    • (2004) Eur. J. Pharmacol. , vol.488 , pp. 1-9
    • Giorgetti, M.1    Tecott, L.H.2
  • 135
    • 0033914588 scopus 로고    scopus 로고
    • Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats
    • Vickers SP, Benwell KR, Porter RH, Bickerdike MJ, Kennett GA, Dourish CT: Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats. Br J Pharmacol 2000;130:1305-1314.
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 1305-1314
    • Vickers, S.P.1    Benwell, K.R.2    Porter, R.H.3    Bickerdike, M.J.4    Kennett, G.A.5    Dourish, C.T.6
  • 136
    • 0032980901 scopus 로고    scopus 로고
    • Serotonin receptor subtype gene expression in the hippocampus of aged rats following chronic amitriptyline treatment
    • Yau JL, Olsson T, Noble J, Seckl JR: Serotonin receptor subtype gene expression in the hippocampus of aged rats following chronic amitriptyline treatment. Brain Res Mol Brain Res 1999;70:282-287.
    • (1999) Brain Res. Mol. Brain Res. , vol.70 , pp. 282-287
    • Yau, J.L.1    Olsson, T.2    Noble, J.3    Seckl, J.R.4
  • 137
    • 0028290842 scopus 로고
    • Lack of effect of antidepressant drugs on the levels of mRNAs encoding serotonergic receptors, synthetic enzymes and 5HT transporter
    • Spurlock G, Buckland P, O'Donovan M, McGuffin P: Lack of effect of antidepressant drugs on the levels of mRNAs encoding serotonergic receptors, synthetic enzymes and 5HT transporter. Neuropharmacology 1994;33:433-440.
    • (1994) Neuropharmacology , vol.33 , pp. 433-440
    • Spurlock, G.1    Buckland, P.2    O'Donovan, M.3    McGuffin, P.4
  • 139
    • 0026532834 scopus 로고
    • Chronic treatment with meta-chlorophenylpiperazine (m-CPP) alters behavioral and cerebral metabolic responses to the serotonin agonists m-CPP and quipazine but not 8-hydroxy-2 (di-N-propylamino) tetralin
    • Freo U, Holloway H W, Greig NH, Soncrant TT: Chronic treatment with meta-chlorophenylpiperazine (m-CPP) alters behavioral and cerebral metabolic responses to the serotonin agonists m-CPP and quipazine but not 8-hydroxy-2 (di-N-propylamino) tetralin. Psychopharmacology (Berl) 1992;107:30-38.
    • (1992) Psychopharmacology (Berl) , vol.107 , pp. 30-38
    • Freo, U.1    Holloway, H.W.2    Greig, N.H.3    Soncrant, T.T.4
  • 140
    • 0026510181 scopus 로고
    • Long-term administration of m-chlorophenylpiperazine (mCPP) to rats induces changes in serotonin receptor binding, dopamine levels and locomotor activity without altering prolactin and corticosterone secretion
    • Ulrichsen J, Partilla JS, Dax EM: Long-term administration of m-chlorophenylpiperazine (mCPP) to rats induces changes in serotonin receptor binding, dopamine levels and locomotor activity without altering prolactin and corticosterone secretion. Psychopharmacology (Berl) 1992;107:229-235.
    • (1992) Psychopharmacology (Berl) , vol.107 , pp. 229-235
    • Ulrichsen, J.1    Partilla, J.S.2    Dax, E.M.3
  • 144
    • 0027849695 scopus 로고
    • Effects of fluoxetine given chronically on the responsiveness of 5-HT receptor subpopulations to their agonists
    • Maj J, Moryl E: Effects of fluoxetine given chronically on the responsiveness of 5-HT receptor subpopulations to their agonists. Eur Neuropsychopharmacol 1993;3:85-94.
    • (1993) Eur. Neuropsychopharmacol. , vol.3 , pp. 85-94
    • Maj, J.1    Moryl, E.2
  • 145
    • 0026561903 scopus 로고
    • Effects of sertraline and citalopram given repeatedly on the responsiveness of 5-HT receptor subpopulations
    • Maj J, Moryl E: Effects of sertraline and citalopram given repeatedly on the responsiveness of 5-HT receptor subpopulations. J Neural Transm Gen Sect 1992;88:143-156.
    • (1992) J. Neural. Transm. Gen. Sect , vol.88 , pp. 143-156
    • Maj, J.1    Moryl, E.2
  • 146
    • 0027144492 scopus 로고
    • Effects of housing, restraint and chronic treatments with mCPP and sertraline on behavioural responses to mCPP
    • Kennedy AJ, Gibson EL, O'Connell MT, Curzon G: Effects of housing, restraint and chronic treatments with mCPP and sertraline on behavioural responses to mCPP. Psychopharmacology (Berl) 1993;113:262-268.
    • (1993) Psychopharmacology (Berl) , vol.113 , pp. 262-268
    • Kennedy, A.J.1    Gibson, E.L.2    O'Connell, M.T.3    Curzon, G.4
  • 147
    • 0024549545 scopus 로고
    • Effect of 1-(m-chlorophenyl) piperazine and 1-(m-trifluoromethylphenyl) piperazine on locomotor activity
    • Lucki I, Ward HR, Frazer A: Effect of 1-(m-chlorophenyl) piperazine and 1-(m-trifluoromethylphenyl) piperazine on locomotor activity. J Pharmacol Exp Ther 1989;249:155-164.
    • (1989) J. Pharmacol. Exp. Ther. , vol.249 , pp. 155-164
    • Lucki, I.1    Ward, H.R.2    Frazer, A.3
  • 148
    • 0029795360 scopus 로고    scopus 로고
    • Daily administration of m-chlorophenylpiperazine to healthy human volunteers rapidly attenuates many of its behavioral, hormonal, cardiovascular and temperature effects
    • Benjamin J, Greenberg BD, Murphy DL: Daily administration of m-chlorophenylpiperazine to healthy human volunteers rapidly attenuates many of its behavioral, hormonal, cardiovascular and temperature effects. Psychopharmacology (Berl) 1996;127:140-149.
    • (1996) Psychopharmacology (Berl) , vol.127 , pp. 140-149
    • Benjamin, J.1    Greenberg, B.D.2    Murphy, D.L.3
  • 149
    • 0030816390 scopus 로고    scopus 로고
    • SSRI treatment decreases prolactin and hyperthermic responses to mCPP
    • Quested DJ, Sargent PA, Cowen PJ: SSRI treatment decreases prolactin and hyperthermic responses to mCPP. Psychopharmacology (Berl) 1997;133:305-308.
    • (1997) Psychopharmacology (Berl) , vol.133 , pp. 305-308
    • Quested, D.J.1    Sargent, P.A.2    Cowen, P.J.3
  • 150
    • 0024501283 scopus 로고
    • Hyperthermia induced by m-CPP in the rat and its modification by antidepressant treatments
    • Wozniak KM, Aulakh CS, Hill JL, Murphy DL: Hyperthermia induced by m-CPP in the rat and its modification by antidepressant treatments. Psychopharmacology (Berl) 1989;97:269-274.
    • (1989) Psychopharmacology (Berl) , vol.97 , pp. 269-274
    • Wozniak, K.M.1    Aulakh, C.S.2    Hill, J.L.3    Murphy, D.L.4
  • 151
    • 0022460663 scopus 로고
    • Suppression of the hypo-and hyperthermic responses to 5-HT agonists following the repeated administration of monoamine oxidase inhibitors
    • Gudelsky GA, Koenig JI, Jackman H, Meltzer HY: Suppression of the hypo-and hyperthermic responses to 5-HT agonists following the repeated administration of monoamine oxidase inhibitors. Psychopharmacology (Berl) 1986;90:403-407.
    • (1986) Psychopharmacology (Berl) , vol.90 , pp. 403-407
    • Gudelsky, G.A.1    Koenig, J.I.2    Jackman, H.3    Meltzer, H.Y.4
  • 155
    • 0027444812 scopus 로고
    • Long-term treatment with the antidepressants fluoxetine and desipramine potentiates endocrine responses to the serotonin agonists 6-chloro-2-[1- piperazinyl]-pyrazine (MK-212) and (+-)-1-(2, 5-dimethoxy-4-iodophenyl)-2- aminopropane HCl (DOI)
    • Li Q, Brownfield MS, Battaglia G, Cabrera TM, Levy AD, Rittenhouse PA, Van de Kar LD: Long-term treatment with the antidepressants fluoxetine and desipramine potentiates endocrine responses to the serotonin agonists 6-chloro-2-[1-piperazinyl]-pyrazine (MK-212) and (+-)-1-(2, 5-dimethoxy-4- iodophenyl)-2-aminopropane HCl (DOI). J Pharmacol Exp Ther 1993;266:836-844.
    • (1993) J. Pharmacol. Exp. Ther. , vol.266 , pp. 836-844
    • Li, Q.1    Brownfield, M.S.2    Battaglia, G.3    Cabrera, T.M.4    Levy, A.D.5    Rittenhouse, P.A.6    Van De Kar, L.D.7
  • 157
    • 0026563307 scopus 로고
    • Comparison of acute and chronic treatment of various serotonergic agents with those of diazepam and idazoxan in the rat elevated X-maze
    • Wright IK, Heaton M, Upton N, Marsden CA: Comparison of acute and chronic treatment of various serotonergic agents with those of diazepam and idazoxan in the rat elevated X-maze. Psychopharmacology (Berl) 1992;107:405-414.
    • (1992) Psychopharmacology (Berl) , vol.107 , pp. 405-414
    • Wright, I.K.1    Heaton, M.2    Upton, N.3    Marsden, C.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.