-
1
-
-
0017284150
-
Hyperphagia and obesity following serotonin depletion by intraventricular p-chlorophenylalanine
-
Breisch ST, Zemlan FP, Hoebel BG 1976 Hyperphagia and obesity following serotonin depletion by intraventricular p-chlorophenylalanine. Science 192:382-385
-
(1976)
Science
, vol.192
, pp. 382-385
-
-
Breisch, S.T.1
Zemlan, F.P.2
Hoebel, B.G.3
-
2
-
-
0017260199
-
Hyperphagia and increased growth in rats after intraventricular injection of 5,7-dihydroxytryptamine
-
Saller CF, Stricker EM 1976 Hyperphagia and increased growth in rats after intraventricular injection of 5,7-dihydroxytryptamine. Science 192:385-387
-
(1976)
Science
, vol.192
, pp. 385-387
-
-
Saller, C.F.1
Stricker, E.M.2
-
3
-
-
0029401072
-
Clinical studies with dexfenfluramine: From past to future
-
Guy-Grand B 1995 Clinical studies with dexfenfluramine: from past to future. Obesity Res 3(Suppl 4):491S-496S
-
(1995)
Obesity Res
, vol.3
, Issue.SUPPL. 4
-
-
Guy-Grand, B.1
-
4
-
-
0031689401
-
A comparison of the effects on central 5-HT function of sibutramine hydrochloride and other weight-modifying agents
-
Heal DJ, Cheetham SC, Prow MR, Martin KF, Buckett WR 1998 A comparison of the effects on central 5-HT function of sibutramine hydrochloride and other weight-modifying agents. Br J Pharmacol 125:301-308
-
(1998)
Br J Pharmacol
, vol.125
, pp. 301-308
-
-
Heal, D.J.1
Cheetham, S.C.2
Prow, M.R.3
Martin, K.F.4
Buckett, W.R.5
-
5
-
-
0023573039
-
Use of a serotonin re-uptake inhibitor, fluoxetine, in the treatment of obesity
-
Levine LR, Rosenblatt S, Bosomworth J 1987 Use of a serotonin re-uptake inhibitor, fluoxetine, in the treatment of obesity. Int J Obes 11(Suppl 3):185-190
-
(1987)
Int J Obes
, vol.11
, Issue.SUPPL. 3
, pp. 185-190
-
-
Levine, L.R.1
Rosenblatt, S.2
Bosomworth, J.3
-
6
-
-
0028909857
-
Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors
-
Tecott LH, Sun LM, Akana SF, Strack AM, Lowenstein DH, Dallman MF, Julius D 1995 Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors. Nature 374:542-546
-
(1995)
Nature
, vol.374
, pp. 542-546
-
-
Tecott, L.H.1
Sun, L.M.2
Akana, S.F.3
Strack, A.M.4
Lowenstein, D.H.5
Dallman, M.F.6
Julius, D.7
-
7
-
-
0028298214
-
An examination of the behavioural specificity of hypophagia induced by 5-HT1B, 5-HT1C and 5-HT2 receptor agonists using the post-prandial satiety sequence in rats
-
Kitchener SJ, Dourish CT 1994 An examination of the behavioural specificity of hypophagia induced by 5-HT1B, 5-HT1C and 5-HT2 receptor agonists using the post-prandial satiety sequence in rats. Psychopharmacology 113:369-377
-
(1994)
Psychopharmacology
, vol.113
, pp. 369-377
-
-
Kitchener, S.J.1
Dourish, C.T.2
-
8
-
-
0028870515
-
Functional assessment of the 5-HT 1A-, 1B-, 2A/2C-, and 3-receptor subtypes on food intake and metabolic rate in rats
-
Bovetto S, Richard D 1995 Functional assessment of the 5-HT 1A-, 1B-, 2A/2C-, and 3-receptor subtypes on food intake and metabolic rate in rats. Am J Physiol 268:R14-R20
-
(1995)
Am J Physiol
, vol.268
-
-
Bovetto, S.1
Richard, D.2
-
9
-
-
0033778106
-
Similarities in the action of Ro 60-0175, a 5-HT2C receptor agonist and d-fenfluramine on feeding patterns in the rat
-
Clifton PG, Lee MD, Dourish CT 2000 Similarities in the action of Ro 60-0175, a 5-HT2C receptor agonist and d-fenfluramine on feeding patterns in the rat. Psychopharmacology 152:256-267
-
(2000)
Psychopharmacology
, vol.152
, pp. 256-267
-
-
Clifton, P.G.1
Lee, M.D.2
Dourish, C.T.3
-
10
-
-
0023678368
-
Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors
-
Kennett GA, Curzon G 1988 Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors. Psychopharmacology 96:93-100
-
(1988)
Psychopharmacology
, vol.96
, pp. 93-100
-
-
Kennett, G.A.1
Curzon, G.2
-
11
-
-
0025827064
-
Potencies of antagonists indicate that 5-HT1C receptors mediate 1-3(chlorophenyl)piperazine-induced hypophagia
-
Kennett GA, Curzon G 1991 Potencies of antagonists indicate that 5-HT1C receptors mediate 1-3(chlorophenyl)piperazine-induced hypophagia. Br J Pharmacol 103:2016-2020
-
(1991)
Br J Pharmacol
, vol.103
, pp. 2016-2020
-
-
Kennett, G.A.1
Curzon, G.2
-
12
-
-
0018654149
-
Chlorophenylpiperazine: A central serotonin agonist causing powerful anorexia in rats
-
Samanin R, Mennini T, Ferraris A, Bendotti C, Borsini F, Garattini S 1979 Chlorophenylpiperazine: a central serotonin agonist causing powerful anorexia in rats. Naunyn Schmiedebergs Arch Pharmacol 308:159-163
-
(1979)
Naunyn Schmiedebergs Arch Pharmacol
, vol.308
, pp. 159-163
-
-
Samanin, R.1
Mennini, T.2
Ferraris, A.3
Bendotti, C.4
Borsini, F.5
Garattini, S.6
-
13
-
-
27544450765
-
Divergence of melanocortin pathways in the control of food intake and energy expenditure
-
Balthasar N, Dalgaard LT, Lee CE, Yu J, Funahashi H, Williams T, Ferreira M, Tang V, McGovern RA, Kenny CD, Christiansen LM, Edelstein E, Choi B, Boss O, Aschkenasi C, Zhang CY, Mountjoy K, Kishi T, Elmquist JK, Lowell BB 2005 Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell 123:493-505
-
(2005)
Cell
, vol.123
, pp. 493-505
-
-
Balthasar, N.1
Dalgaard, L.T.2
Lee, C.E.3
Yu, J.4
Funahashi, H.5
Williams, T.6
Ferreira, M.7
Tang, V.8
McGovern, R.A.9
Kenny, C.D.10
Christiansen, L.M.11
Edelstein, E.12
Choi, B.13
Boss, O.14
Aschkenasi, C.15
Zhang, C.Y.16
Mountjoy, K.17
Kishi, T.18
Elmquist, J.K.19
Lowell, B.B.20
more..
-
14
-
-
33745978779
-
Serotonin reciprocally regulates melanocortin neurons to modulate food intake
-
Heisler LK, Jobst EE, Sutton GM, Zhou L, Borok E, Thornton-Jones Z, Liu HY, Zigman JM, Balthasar N, Kishi T, Lee CE, Aschkenasi CJ, Zhang CY, Yu J, Boss O, Mountjoy KG, Clifton PG, Lowell BB, Friedman JM, Horvath T, Butler AA, Elmquist JK, Cowley MA 2006 Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron 51:239-249
-
(2006)
Neuron
, vol.51
, pp. 239-249
-
-
Heisler, L.K.1
Jobst, E.E.2
Sutton, G.M.3
Zhou, L.4
Borok, E.5
Thornton-Jones, Z.6
Liu, H.Y.7
Zigman, J.M.8
Balthasar, N.9
Kishi, T.10
Lee, C.E.11
Aschkenasi, C.J.12
Zhang, C.Y.13
Yu, J.14
Boss, O.15
Mountjoy, K.G.16
Clifton, P.G.17
Lowell, B.B.18
Friedman, J.M.19
Horvath, T.20
Butler, A.A.21
Elmquist, J.K.22
Cowley, M.A.23
more..
-
15
-
-
12144291698
-
Mice lacking proopiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36)
-
Challis BG, Coll AP, Yeo GS, Pinnock SB, Dickson SL, Thresher RR, Dixon J, Zahn D, Rochford JJ, White A, Oliver RL, Millington G, Aparicio SA, Colledge WH, Russ AP, Carlton MB, O'Rahilly S 2004 Mice lacking proopiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36). Proc Natl Acad Sci USA 101:4695-4700
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4695-4700
-
-
Challis, B.G.1
Coll, A.P.2
Yeo, G.S.3
Pinnock, S.B.4
Dickson, S.L.5
Thresher, R.R.6
Dixon, J.7
Zahn, D.8
Rochford, J.J.9
White, A.10
Oliver, R.L.11
Millington, G.12
Aparicio, S.A.13
Colledge, W.H.14
Russ, A.P.15
Carlton, M.B.16
O'Rahilly, S.17
-
16
-
-
0024463970
-
A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabelled single stranded RNA probes
-
Simmons DM, Arriza JL, Swanson LW 1989 A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabelled single stranded RNA probes. J Histotechnol 12:169-181
-
(1989)
J Histotechnol
, vol.12
, pp. 169-181
-
-
Simmons, D.M.1
Arriza, J.L.2
Swanson, L.W.3
-
17
-
-
0037178730
-
Activation of central melanocortin pathways by fenfluramine
-
Heisler LK, Cowley MA, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Marcus JN, Holstege H, Lee CE, Cone RD, Elmquist JK 2002 Activation of central melanocortin pathways by fenfluramine. Science 297:609-611
-
(2002)
Science
, vol.297
, pp. 609-611
-
-
Heisler, L.K.1
Cowley, M.A.2
Tecott, L.H.3
Fan, W.4
Low, M.J.5
Smart, J.L.6
Rubinstein, M.7
Tatro, J.B.8
Marcus, J.N.9
Holstege, H.10
Lee, C.E.11
Cone, R.D.12
Elmquist, J.K.13
-
18
-
-
0029951646
-
Distribution of Fos-like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration
-
Elmquist JK, Scammell TE, Jacobson CD, Saper CB 1996 Distribution of Fos-like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration. J Comp Neurol 371:85-103
-
(1996)
J Comp Neurol
, vol.371
, pp. 85-103
-
-
Elmquist, J.K.1
Scammell, T.E.2
Jacobson, C.D.3
Saper, C.B.4
-
19
-
-
0027431445
-
Distribution and neurochemical phenotypes of caudal medullary neurons activated to express cFos following peripheral administration of cholecystokinin
-
Rinaman L, Verbalis JG, Stricker EM, Hoffman GE 1993 Distribution and neurochemical phenotypes of caudal medullary neurons activated to express cFos following peripheral administration of cholecystokinin. J Comp Neurol 338:475-490
-
(1993)
J Comp Neurol
, vol.338
, pp. 475-490
-
-
Rinaman, L.1
Verbalis, J.G.2
Stricker, E.M.3
Hoffman, G.E.4
-
20
-
-
28444468797
-
Validation of a selective serotonin 5-HT(2C) receptor antibody for utilization in fluorescence immunohistochemistry studies
-
Bubar MJ, Seitz PK, Thomas ML, Cunningham KA 2005 Validation of a selective serotonin 5-HT(2C) receptor antibody for utilization in fluorescence immunohistochemistry studies. Brain Res 1063:105-113
-
(2005)
Brain Res
, vol.1063
, pp. 105-113
-
-
Bubar, M.J.1
Seitz, P.K.2
Thomas, M.L.3
Cunningham, K.A.4
-
21
-
-
0024722805
-
5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system
-
Molineaux SM, Jessell TM, Axel R, Julius D 1989 5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system. Proc Natl Acad Sci USA 86:6793-6797
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 6793-6797
-
-
Molineaux, S.M.1
Jessell, T.M.2
Axel, R.3
Julius, D.4
-
22
-
-
0030614331
-
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
-
Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD 1997 Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385:165-168
-
(1997)
Nature
, vol.385
, pp. 165-168
-
-
Fan, W.1
Boston, B.A.2
Kesterson, R.A.3
Hruby, V.J.4
Cone, R.D.5
-
23
-
-
33847609962
-
Serotonin and energy balance: Molecular mechanisms and implications for type 2 diabetes
-
Lam DD, Heisler LK 2007 Serotonin and energy balance: molecular mechanisms and implications for type 2 diabetes. Expert Rev Mol Med 9:1-24
-
(2007)
Expert Rev Mol Med
, vol.9
, pp. 1-24
-
-
Lam, D.D.1
Heisler, L.K.2
-
24
-
-
34748903427
-
Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic pro-opiomelanocortin neurons: Role in energy homeostasis in females
-
Qiu J, Xue C, Bosch MA, Murphy JG, Fan W, Ronnekleiv OK, Kelly MJ 2007 Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic pro-opiomelanocortin neurons: role in energy homeostasis in females. Mol Pharmacol 72:885-896
-
(2007)
Mol Pharmacol
, vol.72
, pp. 885-896
-
-
Qiu, J.1
Xue, C.2
Bosch, M.A.3
Murphy, J.G.4
Fan, W.5
Ronnekleiv, O.K.6
Kelly, M.J.7
-
25
-
-
31744434071
-
A negative feedback system between brain serotonin systems and plasma active ghrelin levels in mice
-
Nonogaki K, Ohashi-Nozue K, Oka Y 2006 A negative feedback system between brain serotonin systems and plasma active ghrelin levels in mice. Biochem Biophys Res Commun 341:703-707
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 703-707
-
-
Nonogaki, K.1
Ohashi-Nozue, K.2
Oka, Y.3
-
26
-
-
0037456768
-
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
-
Farooqi IS, Keogh JM, Yeo GS, Lank EJ, Cheetham T, O'Rahilly S 2003 Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N Engl J Med 348:1085-1095
-
(2003)
N Engl J Med
, vol.348
, pp. 1085-1095
-
-
Farooqi, I.S.1
Keogh, J.M.2
Yeo, G.S.3
Lank, E.J.4
Cheetham, T.5
O'Rahilly, S.6
-
27
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F 1997 Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88:131-141
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Lee, F.14
-
28
-
-
0034192443
-
A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences
-
Benoit SC, Schwartz MW, Lachey JL, Hagan MM, Rushing PA, Blake KA, Yagaloff KA, Kurylko G, Franco L, Danhoo W, Seeley RJ 2000 A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences. J Neurosci 20:3442-3448
-
(2000)
J Neurosci
, vol.20
, pp. 3442-3448
-
-
Benoit, S.C.1
Schwartz, M.W.2
Lachey, J.L.3
Hagan, M.M.4
Rushing, P.A.5
Blake, K.A.6
Yagaloff, K.A.7
Kurylko, G.8
Franco, L.9
Danhoo, W.10
Seeley, R.J.11
-
29
-
-
27844445650
-
A novel and selective β-melanocyte-stimulating hormone-derived peptide agonist for melanocortin 4 receptor potently decreased food intake and body weight gain in diet-induced obese rats
-
Hsiung HM, Hertel J, Zhang XY, Smith DP, Smiley DL, Heiman ML, Yang DD, Husain S, Mayer JP, Zhang L, Mo H, Yan LZ 2005 A novel and selective β-melanocyte-stimulating hormone-derived peptide agonist for melanocortin 4 receptor potently decreased food intake and body weight gain in diet-induced obese rats. Endocrinology 146:5257-5266
-
(2005)
Endocrinology
, vol.146
, pp. 5257-5266
-
-
Hsiung, H.M.1
Hertel, J.2
Zhang, X.Y.3
Smith, D.P.4
Smiley, D.L.5
Heiman, M.L.6
Yang, D.D.7
Husain, S.8
Mayer, J.P.9
Zhang, L.10
Mo, H.11
Yan, L.Z.12
-
30
-
-
0031786114
-
Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): Evaluation in vitro and in vivo
-
Kask A, Mutulis F, Muceniece R, Pahkla R, Mutule I, Wikberg JE, Rago L, Schioth HB 1998 Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): evaluation in vitro and in vivo. Endocrinology 139:5006-5014
-
(1998)
Endocrinology
, vol.139
, pp. 5006-5014
-
-
Kask, A.1
Mutulis, F.2
Muceniece, R.3
Pahkla, R.4
Mutule, I.5
Wikberg, J.E.6
Rago, L.7
Schioth, H.B.8
|