An immunocapture/scintillation proximity analysis of Gαq/11 activation by native serotonin (5-HT)2A receptors in rat cortex: Blockade by clozapine and mirtazapine

Synapse

Volumn 63, Issue 2, 2009, Pages 95-105

  La Cour, L C Mannoury ^a   Chaput, C ^a   Touzard, M ^a   Millan, M J ^a  

^a INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Cortex; Gq protein; Scintillation proximity assay; Serotonin 5 ht2a receptors

Indexed keywords

2 (6 CHLORO 5 FLUORO 1 INDOLYL) 1 METHYLETHYLAMINE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; 8 [5 [2,4 DIMETHOXY 5 (4 TRIFLUOROMETHYLPHENYLSULFONAMIDO)PHENYL] 5 OXOPENTYL] 1,3,8 TRIAZASPIRO[4.5]DECANE 2,4 DIONE; ANTIDEPRESSANT AGENT; CLOZAPINE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE 5' O (3 THIOTRIPHOSPHATE) S 35; KETANSERIN; LY 266097; MIRTAZAPINE; PSYCHOTROPIC AGENT; SB 242 084; SEROTONIN 2 ANTAGONIST; SEROTONIN 2A AGONIST; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2B ANTAGONIST; SEROTONIN 2C ANTAGONIST; UNCLASSIFIED DRUG; VOLINANSERIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN TISSUE; CONCENTRATION (PARAMETERS); DRUG BINDING; DRUG MECHANISM; FRONTAL CORTEX; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RECEPTOR AFFINITY; RECEPTOR BLOCKING; SCINTILLATION;

ADRENERGIC ALPHA-ANTAGONISTS; AMPHETAMINES; ANIMALS; CEREBRAL CORTEX; CLOZAPINE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; MALE; MIANSERIN; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT2A; SCINTILLATION COUNTING; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 59949089545     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20587     Document Type: Article

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