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Volumn 187, Issue 1, 2008, Pages 72-79

5-HT2 receptor activation in the midbrain periaqueductal grey (PAG) reduces anxiety-like behaviour in mice

Author keywords

5 HT2 receptors; Anxiety; Elevated plus maze; Ketanserin; mCPP; Mice; PAG

Indexed keywords

KETANSERIN; SEROTONIN 2 RECEPTOR; SEROTONIN 2A ANTAGONIST; SEROTONIN 2B RECEPTOR; SEROTONIN 2C ANTAGONIST; (3 CHLOROPHENYL)PIPERAZINE; 1-(3-CHLOROPHENYL)PIPERAZINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 36749049746     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2007.08.030     Document Type: Article
Times cited : (38)

References (57)
  • 1
    • 33646070874 scopus 로고    scopus 로고
    • Flight reactions induced by injection of glutamate N-methyl-d-aspartate receptor agonist into the rat dorsolateral periaqueductal gray are not dependent on endogenous nitric oxide
    • Aguiar D.C., Moreira F.A., and Guimarães F.S. Flight reactions induced by injection of glutamate N-methyl-d-aspartate receptor agonist into the rat dorsolateral periaqueductal gray are not dependent on endogenous nitric oxide. Pharmacol Biochem Behav 83 (2006) 296-301
    • (2006) Pharmacol Biochem Behav , vol.83 , pp. 296-301
    • Aguiar, D.C.1    Moreira, F.A.2    Guimarães, F.S.3
  • 4
    • 0021951462 scopus 로고
    • Identification of midbrain neurones mediating defensive behaviour in the rat by microinjections of excitatory amino acids
    • Bandler R., Depaulis A., and Vergnes M. Identification of midbrain neurones mediating defensive behaviour in the rat by microinjections of excitatory amino acids. Behav Brain Res 15 2 (1985) 107-119
    • (1985) Behav Brain Res , vol.15 , Issue.2 , pp. 107-119
    • Bandler, R.1    Depaulis, A.2    Vergnes, M.3
  • 5
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5-HT receptors and their function
    • Barnes N.M., and Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology 38 (1999) 1083-1152
    • (1999) Neuropharmacology , vol.38 , pp. 1083-1152
    • Barnes, N.M.1    Sharp, T.2
  • 6
    • 0032920544 scopus 로고    scopus 로고
    • Attenuated response to m-CPP and to pentagastrin after repeated m-CPP in panic disorder
    • Benjamin J., Geraci M., McGann U., Greenberg B.D., and Murphy D.L. Attenuated response to m-CPP and to pentagastrin after repeated m-CPP in panic disorder. Psychopharmacology 143 (1999) 215-216
    • (1999) Psychopharmacology , vol.143 , pp. 215-216
    • Benjamin, J.1    Geraci, M.2    McGann, U.3    Greenberg, B.D.4    Murphy, D.L.5
  • 7
    • 0031916179 scopus 로고    scopus 로고
    • mCPP-induced anxiety in the light-dark box in rats-a new method for screening anxiolytic activity
    • Bilkei-Gorzo A., Gyertyan I., and Levay G. mCPP-induced anxiety in the light-dark box in rats-a new method for screening anxiolytic activity. Psychopharmacology 139 (1998) 291-298
    • (1998) Psychopharmacology , vol.139 , pp. 291-298
    • Bilkei-Gorzo, A.1    Gyertyan, I.2    Levay, G.3
  • 8
    • 0034666602 scopus 로고    scopus 로고
    • Venlafaxine and its interaction with WAY 100635: effects on serotonergic units activity and behavior in cats
    • Bjorvatn B., Fornal C.A., Martín F.J., Metzler C.W., and Jacobs B.L. Venlafaxine and its interaction with WAY 100635: effects on serotonergic units activity and behavior in cats. Eur J Pharmacol 404 (2000) 121-132
    • (2000) Eur J Pharmacol , vol.404 , pp. 121-132
    • Bjorvatn, B.1    Fornal, C.A.2    Martín, F.J.3    Metzler, C.W.4    Jacobs, B.L.5
  • 9
    • 0023800192 scopus 로고
    • Ethoexperimental approaches to the biology of emotion
    • Blanchard R.J., and Blanchard D.C. Ethoexperimental approaches to the biology of emotion. Annu Rev Psychol 39 (1988) 43-68
    • (1988) Annu Rev Psychol , vol.39 , pp. 43-68
    • Blanchard, R.J.1    Blanchard, D.C.2
  • 10
    • 0032819493 scopus 로고    scopus 로고
    • Serotonin and drug-induced therapeutic responses in major depression, obsessive-compulsive and panic disorders
    • Blier P., and de Montigny C. Serotonin and drug-induced therapeutic responses in major depression, obsessive-compulsive and panic disorders. Neuropsychopharmacology 21 2S (1999) 91-98
    • (1999) Neuropsychopharmacology , vol.21 , Issue.2 S , pp. 91-98
    • Blier, P.1    de Montigny, C.2
  • 11
    • 0037154716 scopus 로고    scopus 로고
    • Anxiolytic-like effect of WAY-100635 microinfusions into the median (but not dorsal) raphe nucleus in mice exposed to the plus-maze: influence of prior test experience
    • Canto-de-Souza A., Nunes-de-Souza R.L., and Rodgers R.J. Anxiolytic-like effect of WAY-100635 microinfusions into the median (but not dorsal) raphe nucleus in mice exposed to the plus-maze: influence of prior test experience. Brain Res 928 (2002) 50-59
    • (2002) Brain Res , vol.928 , pp. 50-59
    • Canto-de-Souza, A.1    Nunes-de-Souza, R.L.2    Rodgers, R.J.3
  • 12
    • 33751074424 scopus 로고    scopus 로고
    • Physical environment modulates the behavioral responses induced by chemical stimulation of dorsal periaqueductal gray in mice
    • Carvalho-Netto E.F., Markham C., Blanchard C.D., Nunes-de-Souza R.L., and Blanchard R.J. Physical environment modulates the behavioral responses induced by chemical stimulation of dorsal periaqueductal gray in mice. Pharmacol Biochem Behav 85 (2006) 140-147
    • (2006) Pharmacol Biochem Behav , vol.85 , pp. 140-147
    • Carvalho-Netto, E.F.1    Markham, C.2    Blanchard, C.D.3    Nunes-de-Souza, R.L.4    Blanchard, R.J.5
  • 13
    • 0036932578 scopus 로고    scopus 로고
    • Role of benzodiazepine and serotonergic mechanisms in conditioned freezing and antinociception using electrical stimulation of the dorsal periaqueductal gray as unconditioned stimulus in rats
    • Castilho V.M., de Macedo C.E., and Brandão M.L. Role of benzodiazepine and serotonergic mechanisms in conditioned freezing and antinociception using electrical stimulation of the dorsal periaqueductal gray as unconditioned stimulus in rats. Psychopharmacology 165 (2002) 77-85
    • (2002) Psychopharmacology , vol.165 , pp. 77-85
    • Castilho, V.M.1    de Macedo, C.E.2    Brandão, M.L.3
  • 14
    • 0023179757 scopus 로고
    • Serotonin function in anxiety. II. Effects of the serotonin agonist mCPP on panic disorder patients and healthy subjects
    • Charney D.S., Woods S.W., Goodman W.K., and Heninger G.R. Serotonin function in anxiety. II. Effects of the serotonin agonist mCPP on panic disorder patients and healthy subjects. Psychopharmacology (Berl) 92 (1987) 14-21
    • (1987) Psychopharmacology (Berl) , vol.92 , pp. 14-21
    • Charney, D.S.1    Woods, S.W.2    Goodman, W.K.3    Heninger, G.R.4
  • 16
    • 33846937581 scopus 로고    scopus 로고
    • Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze
    • Cornélio A.M., and Nunes-de-Souza R.L. Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze. Behav Brain Res 178 (2007) 82-89
    • (2007) Behav Brain Res , vol.178 , pp. 82-89
    • Cornélio, A.M.1    Nunes-de-Souza, R.L.2
  • 17
    • 0027932914 scopus 로고
    • Ethopharmacological analysis of rat behavior on the elevated plus-maze
    • Cruz A.P.M., Frei F., and Graeff F.G. Ethopharmacological analysis of rat behavior on the elevated plus-maze. Pharmacol Biochem Behav 49 (1994) 171-176
    • (1994) Pharmacol Biochem Behav , vol.49 , pp. 171-176
    • Cruz, A.P.M.1    Frei, F.2    Graeff, F.G.3
  • 18
    • 26844499950 scopus 로고    scopus 로고
    • Behavioral effects of systemically administered MK-212 are prevented by ritanserin microinfusion into the basolateral amygdala of rats exposed to the elevated plus-maze
    • Cruz A.P.M., Pinheiro G., Alves S.H., Ferreira G., Mendes M., Faria L., et al. Behavioral effects of systemically administered MK-212 are prevented by ritanserin microinfusion into the basolateral amygdala of rats exposed to the elevated plus-maze. Psychopharmacology 182 (2005) 345-354
    • (2005) Psychopharmacology , vol.182 , pp. 345-354
    • Cruz, A.P.M.1    Pinheiro, G.2    Alves, S.H.3    Ferreira, G.4    Mendes, M.5    Faria, L.6
  • 19
    • 0036202493 scopus 로고    scopus 로고
    • A novel behavioral model that discriminates between 5-HT2A and 5-HT2C receptor activation
    • Dave K.D., Harvey J.A., and Aloyo V.J. A novel behavioral model that discriminates between 5-HT2A and 5-HT2C receptor activation. Pharmacol Biochem Behav 72 1/2 (2002) 371-378
    • (2002) Pharmacol Biochem Behav , vol.72 , Issue.1-2 , pp. 371-378
    • Dave, K.D.1    Harvey, J.A.2    Aloyo, V.J.3
  • 21
    • 0021251826 scopus 로고
    • Flight induced by infusion of bicuculline methiodide into periventricular structures
    • Di Scala G., Schmitt P., and Karli P. Flight induced by infusion of bicuculline methiodide into periventricular structures. Brain Res 309 2 (1984) 199-208
    • (1984) Brain Res , vol.309 , Issue.2 , pp. 199-208
    • Di Scala, G.1    Schmitt, P.2    Karli, P.3
  • 23
    • 0003143197 scopus 로고
    • Behavioural detection of anxiolytic action
    • Elliott J.M., Heal D.J., and Marsden C.A. (Eds), John Wiley and Sons, Chichester
    • File S.E. Behavioural detection of anxiolytic action. In: Elliott J.M., Heal D.J., and Marsden C.A. (Eds). Experimental approaches to anxiety and depression (1992), John Wiley and Sons, Chichester 25-44
    • (1992) Experimental approaches to anxiety and depression , pp. 25-44
    • File, S.E.1
  • 24
    • 0030425699 scopus 로고    scopus 로고
    • WAY-100635, a potent and selective 5-hydroxytryptamine1A antagonist, increases serotonergic neuronal activity in behaving cats: comparison with (S)-WAY-100135
    • Fornal C.A., Metzler C.W., Gallegos R.A., Veasey S.C., McCreary A.C., and Jacobs B.L. WAY-100635, a potent and selective 5-hydroxytryptamine1A antagonist, increases serotonergic neuronal activity in behaving cats: comparison with (S)-WAY-100135. J Pharmacol Exp Ther 27 (1996) 752-762
    • (1996) J Pharmacol Exp Ther , vol.27 , pp. 752-762
    • Fornal, C.A.1    Metzler, C.W.2    Gallegos, R.A.3    Veasey, S.C.4    McCreary, A.C.5    Jacobs, B.L.6
  • 26
  • 27
    • 3042549948 scopus 로고    scopus 로고
    • Serotonin, the periaqueductal gray and panic
    • Graeff F.G. Serotonin, the periaqueductal gray and panic. Neurosci Biobehav Rev 3 (2004) 239-259
    • (2004) Neurosci Biobehav Rev , vol.3 , pp. 239-259
    • Graeff, F.G.1
  • 28
    • 0026076573 scopus 로고
    • m-Chlorophenylpiperazine enhances neophobic and anxious behaviours in mice
    • Griebel G., Misslin R., Pawlowski M., and Vogel E. m-Chlorophenylpiperazine enhances neophobic and anxious behaviours in mice. NeuroReport 2 (1991) 627-629
    • (1991) NeuroReport , vol.2 , pp. 627-629
    • Griebel, G.1    Misslin, R.2    Pawlowski, M.3    Vogel, E.4
  • 29
    • 0028986825 scopus 로고
    • 5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: more than 30 years of research
    • Griebel G. 5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: more than 30 years of research. Pharmacol Ther 65 (1995) 319-395
    • (1995) Pharmacol Ther , vol.65 , pp. 319-395
    • Griebel, G.1
  • 31
    • 0028183017 scopus 로고
    • VII International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin)
    • Hoyer D., Clarke D.E., Fozard J.R., Hartig P.R., Martin G.R., Mylecharane E.J., et al. VII International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). J Pharmacol Exp Ther 46 (1994) 157-203
    • (1994) J Pharmacol Exp Ther , vol.46 , pp. 157-203
    • Hoyer, D.1    Clarke, D.E.2    Fozard, J.R.3    Hartig, P.R.4    Martin, G.R.5    Mylecharane, E.J.6
  • 32
    • 0036836189 scopus 로고    scopus 로고
    • 2C receptor mediation of unconditioned escape behaviour in the unstable elevated exposed plus-maze
    • 2C receptor mediation of unconditioned escape behaviour in the unstable elevated exposed plus-maze. Psychopharmacology 164 (2002) 214-220
    • (2002) Psychopharmacology , vol.164 , pp. 214-220
    • Jones, N.1    Duxon, M.S.2    King, S.M.3
  • 34
    • 0025986163 scopus 로고
    • Anxiogenic effects of m-CPP in patients with panic disorder: comparison of caffeine's anxiogenic effects
    • Klein E., Zohar J., Geraci M.F., Murphy D.L., and Udhe T.W. Anxiogenic effects of m-CPP in patients with panic disorder: comparison of caffeine's anxiogenic effects. Biol Psychiatry 30 (1991) 973-984
    • (1991) Biol Psychiatry , vol.30 , pp. 973-984
    • Klein, E.1    Zohar, J.2    Geraci, M.F.3    Murphy, D.L.4    Udhe, T.W.5
  • 35
    • 0023255981 scopus 로고
    • The use of a plus-maze to measure anxiety in the mouse
    • Lister R.G. The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology 92 (1987) 180-185
    • (1987) Psychopharmacology , vol.92 , pp. 180-185
    • Lister, R.G.1
  • 36
    • 0033018708 scopus 로고    scopus 로고
    • Effects of centrally administered anxiolytic compounds in animal models of anxiety
    • Menard J., and Treit D. Effects of centrally administered anxiolytic compounds in animal models of anxiety. Neurosci Biobehav Rev 23 (1999) 591-613
    • (1999) Neurosci Biobehav Rev , vol.23 , pp. 591-613
    • Menard, J.1    Treit, D.2
  • 37
    • 33644917752 scopus 로고    scopus 로고
    • Defensive-like behaviors and antinociception induced by NMDA injection into the periaqueductal gray of mice depend on nitric oxide synthesis
    • Miguel T.T., and Nunes-de-Souza R.L. Defensive-like behaviors and antinociception induced by NMDA injection into the periaqueductal gray of mice depend on nitric oxide synthesis. Brain Res 1076 (2006) 42-48
    • (2006) Brain Res , vol.1076 , pp. 42-48
    • Miguel, T.T.1    Nunes-de-Souza, R.L.2
  • 38
    • 0142216081 scopus 로고    scopus 로고
    • The neurobiology and control of anxious states
    • Millan M.J. The neurobiology and control of anxious states. Progr Neurobiol 70 (2003) 83-244
    • (2003) Progr Neurobiol , vol.70 , pp. 83-244
    • Millan, M.J.1
  • 40
    • 0022411912 scopus 로고
    • Neuroendocrine effects of m-chlorophenylpiperazine, a serotonin agonist, in humans
    • Mueller E.A., Murphy D.L., and Sunderland T. Neuroendocrine effects of m-chlorophenylpiperazine, a serotonin agonist, in humans. J Clin Endocrinol Metab 61 (1985) 1179-1184
    • (1985) J Clin Endocrinol Metab , vol.61 , pp. 1179-1184
    • Mueller, E.A.1    Murphy, D.L.2    Sunderland, T.3
  • 41
    • 0029670670 scopus 로고    scopus 로고
    • Effects of 8-OHDPAT and 5-HT1A antagonists WAY100135 and WAY100635, on guinea-pig behaviour and dorsal raphe 5-HT neurone firing
    • Mundey M.K., Fletcher A., and Marsden C.A. Effects of 8-OHDPAT and 5-HT1A antagonists WAY100135 and WAY100635, on guinea-pig behaviour and dorsal raphe 5-HT neurone firing. Br J Pharmacol 117 (1996) 750-756
    • (1996) Br J Pharmacol , vol.117 , pp. 750-756
    • Mundey, M.K.1    Fletcher, A.2    Marsden, C.A.3
  • 43
    • 0003101035 scopus 로고
    • 5-HT mediation of the antiaversive effect of isamoltane injected into the dorsal periaqueductal grey
    • Nogueira R.L., and Graeff F.G. 5-HT mediation of the antiaversive effect of isamoltane injected into the dorsal periaqueductal grey. Behav Pharmacol 2 1 (1991) 73-77
    • (1991) Behav Pharmacol , vol.2 , Issue.1 , pp. 73-77
    • Nogueira, R.L.1    Graeff, F.G.2
  • 44
    • 0033920921 scopus 로고    scopus 로고
    • Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam
    • Nunes-de-Souza R.L., Canto-de-Souza A., Da-Costa M., Fornari R.V., Pelá I.R., and Graeff F.G. Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam. Psychopharmacology 150 (2000) 300-310
    • (2000) Psychopharmacology , vol.150 , pp. 300-310
    • Nunes-de-Souza, R.L.1    Canto-de-Souza, A.2    Da-Costa, M.3    Fornari, R.V.4    Pelá, I.R.5    Graeff, F.G.6
  • 45
    • 0037039533 scopus 로고    scopus 로고
    • Effects of intra-hippocampal infusion of WAY 100635 on plus-maze behavior in mice. Influence of site of injection and prior test experience
    • Nunes-de-Souza R.L., Canto-de-Souza A., and Rodgers R.J. Effects of intra-hippocampal infusion of WAY 100635 on plus-maze behavior in mice. Influence of site of injection and prior test experience. Brain Res 9 (2002) 87-96
    • (2002) Brain Res , vol.9 , pp. 87-96
    • Nunes-de-Souza, R.L.1    Canto-de-Souza, A.2    Rodgers, R.J.3
  • 48
    • 0027056458 scopus 로고
    • Anxiogenic-like effects of fluprazine and eltoprazine in the mouse elevated plus-maze: profile comparisons with 8-OH-DPAT, CGS12066B, TFMPP and mCPP
    • Rodgers R.J., Cole J.C., Cobain M.R., Daly P., Doran P.J., Eells J.R., et al. Anxiogenic-like effects of fluprazine and eltoprazine in the mouse elevated plus-maze: profile comparisons with 8-OH-DPAT, CGS12066B, TFMPP and mCPP. Behav Pharmacol 3 (1992) 621-634
    • (1992) Behav Pharmacol , vol.3 , pp. 621-634
    • Rodgers, R.J.1    Cole, J.C.2    Cobain, M.R.3    Daly, P.4    Doran, P.J.5    Eells, J.R.6
  • 49
    • 0029083245 scopus 로고
    • Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety
    • Rodgers R.J., and Johnson N.J.T. Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety. Pharmacol Biochem Behav 52 (1995) 297-303
    • (1995) Pharmacol Biochem Behav , vol.52 , pp. 297-303
    • Rodgers, R.J.1    Johnson, N.J.T.2
  • 50
    • 0028075302 scopus 로고
    • Behavioural and pharmacological characterisation of the elevated 'zero-maze' as an animal model of anxiety
    • Shepherd J.K., Grewal S.S., Fletcher A., Bill D.J., and Dourish C.T. Behavioural and pharmacological characterisation of the elevated 'zero-maze' as an animal model of anxiety. Psychopharmacology 116 (1994) 56-64
    • (1994) Psychopharmacology , vol.116 , pp. 56-64
    • Shepherd, J.K.1    Grewal, S.S.2    Fletcher, A.3    Bill, D.J.4    Dourish, C.T.5
  • 51
    • 4444365487 scopus 로고    scopus 로고
    • Involvement of 5-HT1A and 5-HT2 receptors of the dorsal periaqueductal gray in the regulation of the defensive behaviors generated by the elevated T-maze
    • Soares V.P., and Zangrossi Jr. H. Involvement of 5-HT1A and 5-HT2 receptors of the dorsal periaqueductal gray in the regulation of the defensive behaviors generated by the elevated T-maze. Brain Res Bull 64 (2004) 181-188
    • (2004) Brain Res Bull , vol.64 , pp. 181-188
    • Soares, V.P.1    Zangrossi Jr., H.2
  • 53
    • 0027476023 scopus 로고
    • Anxiogenic stimuli in the elevated plus-maze
    • Treit D., Menard J., and Royan C. Anxiogenic stimuli in the elevated plus-maze. Pharmacol Biochem Behav 44 (1993) 463-469
    • (1993) Pharmacol Biochem Behav , vol.44 , pp. 463-469
    • Treit, D.1    Menard, J.2    Royan, C.3
  • 54
    • 0033577751 scopus 로고    scopus 로고
    • Projections of the median raphe nucleus in the rat
    • Vertes R.P., Fortin W.J., and Crane A.M. Projections of the median raphe nucleus in the rat. J Comp Neurol 407 (1999) 555-582
    • (1999) J Comp Neurol , vol.407 , pp. 555-582
    • Vertes, R.P.1    Fortin, W.J.2    Crane, A.M.3
  • 55
    • 0025095142 scopus 로고
    • Anxiogenic-like effect of infusing 1-(3-chlorophenyl) piperazine (mCPP) into the hippocampus
    • Whitton P., and Curzon G. Anxiogenic-like effect of infusing 1-(3-chlorophenyl) piperazine (mCPP) into the hippocampus. Psychopharmacology 100 (1990) 138-140
    • (1990) Psychopharmacology , vol.100 , pp. 138-140
    • Whitton, P.1    Curzon, G.2
  • 56
    • 0027946657 scopus 로고
    • Behavioral effects of intra-amygdala injections of GABA and 5-HT acting drugs in the elevated plus-maze
    • Zangrossi H., and Graeff F.G. Behavioral effects of intra-amygdala injections of GABA and 5-HT acting drugs in the elevated plus-maze. Braz J Med Biol Res 27 (1994) 2453-2456
    • (1994) Braz J Med Biol Res , vol.27 , pp. 2453-2456
    • Zangrossi, H.1    Graeff, F.G.2


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