Chronic citalopram and fluoxetine treatments upregulate 5-HT(2C) receptors in the rat choroid plexus

Neuropsychopharmacology

Volumn 15, Issue 2, 1996, Pages 143-151

  Laakso, Aki ^a   Pälvimäki, Esa Pekka ^a   Kuoppamäki, Mikko ^a   Syvälahti, Erkka ^a   Hietala, Jarmo ^a  

^a UNIVERSITY OF TURKU   (Finland)

Author keywords

5 HT(2C) receptor; Choroid plexus; Citalopram; Fluoxetine; Rat; Serotonin

Indexed keywords

CITALOPRAM; FLUOXETINE; MESULERGINE; SEROTONIN 1C RECEPTOR; SEROTONIN UPTAKE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; CHOROID PLEXUS; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; RECEPTOR UPREGULATION; SEROTONINERGIC SYSTEM; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030222289     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0893-133X(95)00176-E     Document Type: Article

References (66)

1. Aghajanian GK, Gallager DW (1975): Raphe origin of serotonergic nerves terminating in the cerebral ventricles. Brain Res 88:221-231
2. 1C receptors in rat brain. J Pharmacol Exp Ther 255:843-857
3. 1C receptor density and mRNA levels in choroid plexus epithelial cells after treatment with mianserin and (-)-1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. Mol Pharmacol 44:725-730
4. Beasley CM, Masica DN, Potvin JH (1992): Fluoxetine: A review of receptor and functional effects and their clinical implications. Psychopharmacology 107:1-10
5. Bel N, Artigas F (1993): Chronic treatment with fluvoxamine increases extracellular serotonin in frontal cortex but not in raphe nuclei. Synapse 15:243-245
6. Berendsen HHG, Broekkamp CLE (1994): Comparison of stimulus properties of fluoxetine and 5-HT receptor agonists in a conditioned taste aversion procedure. Eur J Pharmacol 253:83-89
7. Blier P, Chaput Y, de Montigny C (1988): Long-term 5-HT reuptake blockade, but not monoamine oxidase inhibition, decreases the function of terminal 5-HT autoreceptors: An electrophysiological study in the rat brain. Naunyn-Schmiedeberg's Arch Pharmacol 337:246-254
8. 1C sites. Eur J Pharmacol 191:93-96
9. Cesana R, Ceci A, Ciprandi C, Borsini F (1993): Mesulergine antagonism towards the fluoxetine anti-immobility effect in the forced swimming test in mice. J Pharm Pharmacol 45:473-475
10. Chan-Palay V (1976): Serotonin axons in the supra- and sub-ependymal plexuses and in the leptomeninges; their roles in local alterations of cerebrospinal fluid and vasomotor activity. Brain Res 102:103-130
11. Chaput Y, de Montigny C, Blier P (1986): Effects of selective 5-HT reuptake blocker, citalopram, on the sensitivity of 5-HT autoreceptors: Electrophysiological studies in the rat brain. Naunyn-Schmiedeberg's Arch Pharmacol 333:342-348
12. Chaput Y, de Montigny C, Blier B (1991): Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments: An in vivo electrophysiological study in the rat. Neuropsychopharmacology 5:219-229
13. 1C receptors in rat choroid plexus. Brain Res 400:396-398
14. 1C receptors. Trends Pharmacol Sci 11:181-182
15. de Montigny C, Chaput Y, Blier P (1990): Modification of serotonergic neuron properties by long-term treatment with serotonin reuptake blockers. J Clin Psychiatr (suppl B) 51:4-8
16. Fluoxetine Bulimia Nervosa Collaborative Study Group (1992): Fluoxetine in the treatment of bulimia nervosa. A multicenter, placebo-controlled, double-blind trial. Arch Gen Psychiatr 49:139-147
17. Fuller RW (1994): Uptake inhibitors increase extracellular serotonin concentration measured by brain microdialysis. Life Sci 55:163-167
18. Geary WA, Wooten GF (1985): Regional tritium quenching in quantitative autoradiography of the central nervous system. Brain Res 336:334-336
19. 1C cell lines. Brain Res 584:191-196
20. Hietala J, Koulu M, Kuoppamäki M, Lappalainen J, Syvälahti E (1992): Chronic clozapine treatment down-regulates serotonin 5-HT-1c receptors in rat brain. Prog Neuropsychopharmacol Biol Psychiatr 16:727-732
21. 1A autoreceptor desensitization following chronic citalopram treatment, as determined by in vivo microdialysis. Neuropharmacology 33:331-334
22. 1C receptor mRNa in adult rat brain. FEBS Lett 247:453-462
23. Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PPA (1994): VII. International Union of Pharmacology Classification of Receptors for 5-Hydroxytryptamine (Serotonin). Pharmacol Rev 46:157-203
24. Humphrey PPA, Hartig P, Hoyer D (1993): A proposed new nomenclature for 5-HT receptors. Trends Pharmacol Sci 14:233-236
25. Hyttel J, Overø KF, Arnt J (1984): Biochemical effects and drug levels in rats after long-term treatment with the specific 5-HT-uptake inhibitor, citalopram. Psychopharmacology 83:20-27
26. 1A receptors. Eur J Pharmacol 260:243-246
27. 1C receptors in the antiserotonergic properties of some antidepressant drugs. Eur J Pharmacol 231:223-229
28. Johnson AM (1991): The comparative pharmacological properties of selective serotonin reuptake inhibitors in animals. In Feighner JP, Boyer WF (eds), Selective Serotonin Re-uptake Inhibitors. Chichester, Wiley, pp. 37-70
29. 2C/2B receptor function. Neuropharmacology 33:1581-1588
30. König JFR, Klippel RA (1963): The Rat Brain. A Stereotaxic Atlas of the Forebrain and Lower Parts of the Brain Stem. Huntington, Robert E. Krieger
31. 1C receptor-mediated phosphoinositide hydrolysis in the rat choroid plexus after chronic treatment with clozapine. Eur J Pharmacol 255:91-97
32. 2 receptors. Mol Pharmacol 42:328-335
33. Lesch K-P, Aulakh CS, Wolozin BL, Murphy DL (1992): Serotonin (5-HT) receptor, 5-HT transporter and G-protein-effector expression: Implications for depression. Pharmacol Toxicol 71 (Suppl 1):49-60
34. Li Q, Brownfield MS, Battaglia G, Cabrera TM, Levy AD, Rittenhouse PA, Van De Kar LD (1993): Long-term treatment with the antidepressants fluoxetine and desipramine potentiates endocrine responses to the serotonin agonists 6-chloro-2-[1-piperazinyl]-pyrazine (MK-212) and (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane HCl (DOI). J Pharmacol Exp Ther 266;836-844
35. Lidov HGW, Grzanna R, Molliver ME (1980): The serotonin innervation of the cerebral cortex in the rat - An immunohistochemical analysis. Neuroscience 5:207-227
36. Maj J, Moryl E (1992): Effects of sertraline and citalopram given repeatedly on the responsiveness of 5-HT receptor subpopulations. J Neural Transm 88:143-156
37. Maj J, Moryl E (1993): Effects of fluoxetine given chronically on the responsiveness of 5-HT receptor subpopulations to their agonists. Eur Neuropsychopharmacol 3:85-94
38. Mengod G, Nguyen H, Le H, Waeber C, Lübbert H, Palacios JM (1990): The distribution and cellular localization of the serotonin 1c receptor mRNA in the rodent brain examined by in situ hybridization histochemistry. Comparison with receptor binding distribution. Neuroscience 35:577-591
39. 1c receptor is a prominent serotonin receptor subtype in the central nervous system. Proc Natl Acad Sci USA 86:6793-6797
40. Moore RY, Halaris AE, Jones BE (1978): Serotonin neurons of the midbrain raphe: Ascending projections. J Comp Neurol 180:417-438
41. Moskovitz MA, Liebmann JE, Reinhard JF Jr, Schlosberg A (1979): Raphe origin of serotonin-containing neurons within choroid plexus of the rat. Brain Res 169:590-594
42. Napoleone P, Sancesario G, Amenta F (1982): Indolaminergic innervation of rat choroid plexus: A fluorescence histochemical study. Neurosci Lett 34:143-147
43. Nilsson C, Lindvall-Axelsson M, Owman C (1992): Neuroendocrine regulatory mechanisms in the choroid plexus-cerebrospinal fluid system. Brain Res Rev 17:109-138
44. Pazos A, Hover D, Palacios JM (1984): The binding of serotonergic ligands to the porcine choroid plexus: Characterization of a new type of serotonin recognition site. Eur J Pharmacol 106:539-546
45. 2C receptors. Mol Brain Res 23:163-178
46. 1C/2 receptor agonists. Eur J Pharmacol Mol Pharmacol Section 244:1-5
47. 1C receptors in the rat brain. Neuroscience 56:687-693
48. 1C serotonin receptor levels. Methodology and mechanisms. Neuropsychopharmacology 3:427-433
49. 1C receptors. J Pharmacol Exp Ther 260: 1361-1365
50. Rutter JJ, Auerbach SB (1993): Acute uptake inhibition increases extracellular serotonin in the rat forebrain. J Pharmacol Exp Ther 265:1319-1324
51. Rutter JJ, Gundlah C, Auerbach SB (1994): Increase in extracellular serotonin produced by uptake inhibitors is enhanced after chronic treatment with fluoxetine. Neurosci Lett 171:183-186
52. Salter M, Hazelwood R, Pogson CI, Iyer R, Madge DJ, Jones HT, Cooper BR, Cox RF, Wang CM, Wiard RP (1995): The effects of an inhibitor of tryptophan 2,3-dioxygenase and a combined inhibitor of tryptophan 2,3-dioxygenase and 5-HT reuptake in the rat. Neuropharmacology 34:217-227
53. 1c receptors in the choroid plexus. J Pharmacol Exp Ther 247:169-173
54. Sanders-Bush E, Breeding M (1990): Serotoninic receptor reserve in choroid plexus masks receptor subsensitivity J Pharmacol Exp Ther 242:984-988
55. 1C receptor actiation by hallucinogenic drugs. Psychopharmacology 105:340-346
56. Spurlock G, Buckland P, O'Donovan M, McGuffin P (1994): Lack of effect of antidepressant drugs on the levels of mRNAs encoding serotonergic receptors, synthetic enzymes and 5-HT transporter. Neuropharmacology 33: 433-440
57. Steinbusch HWM (1981): Distribution of serotonin-immunoreactivity in the central nervous system of the rat cell bodies and terminals. Neuroscience 6:557-618
58. 2C serotonin receptors. Nature 374:542-546
59. Ternaux JP, Boireau A, Bourgoin S, Hamon M, Hery F, Glowinski J (1976): In vivo release of 5-HT in the lateral ventricle of the rat: The effects of 5-hydroxy-tryptophan and tryptophan. Brain Res 101:533-548
60. Ternaux JP, Hery F, Hamon M, Bourgoin S, Glowinski J (1977): 5-HT release from ependymal surface of the caudate nucleus in "encéphale isolé" cats. Brain Res 132:575-579
61. Tollefson GD, Rampey AH, Potvin JH, Jenike MA, Rush AJ, Dominguez RA, Koran ML, Shear MK, Goodman W, Genduso LA (1994): A multicenter investigation of fixed-dose fluoxetine in the treatment of obsessive-compulsive disorder. Arch Gen Psychiatr 51:559-567
62. Torok-Both GA, Baker GB, Coutts RT, McKenna KF, Aspeslet LJ (1992): Simultaneous determination of fluoxetine and norfluoxetine enantiomers in biological samples by gas chromatography with electron-capture detection. J Chromatogr 579:99-106
63. Trouvin JH, Gardier AM, Chanut E, Pages N, Jacquot C (1993): Time course of brain serotonin metabolism after cessation of long-term fluoxetine treatment in the rat. Life Sci 52:187-192
64. Wong DT, Threlkeld PG, Robertson DW (1991): Affinities of fluoxetine, its enantiomers, and other inhibitors of serotonin uptake for subtypes of serotonin receptors. Neuropsychopharmacology 5:43-47
65. Wong DT, Bymaster FP, Reid LR, Mayle DA, Krushinski JH, Robertson DW (1993): Norfluoxetine enantiomers as inhibitors of serotonin uptake in rat brain. Neuropsychopharmacology 8:337-344
66. 125I-Lysergic acid diethylamide binds to a novel serotonergic site on rat choroid plexus epithelial cells. J Neurosci 5:3178-3183