-
1
-
-
0031475025
-
Mutations of the conserved DRS motif in the second intracellular loop of the gonadotropin-releasing hormone receptor affect expression, activation, and internalization
-
Arora KK, Cheng Z, and Catt KJ (1997) Mutations of the conserved DRS motif in the second intracellular loop of the gonadotropin-releasing hormone receptor affect expression, activation, and internalization. Mol Endocrinol 11:1203-1212.
-
(1997)
Mol Endocrinol
, vol.11
, pp. 1203-1212
-
-
Arora, K.K.1
Cheng, Z.2
Catt, K.J.3
-
2
-
-
0029081150
-
Effects of second intracellular loop mutations on signal transduction and internalization of the gonadotropin-releasing hormone receptor
-
Arora KK, Sakai A, and Catt KJ (1995) Effects of second intracellular loop mutations on signal transduction and internalization of the gonadotropin-releasing hormone receptor. J Biol Chem 270:22820-22826.
-
(1995)
J Biol Chem
, vol.270
, pp. 22820-22826
-
-
Arora, K.K.1
Sakai, A.2
Catt, K.J.3
-
3
-
-
0032562699
-
Functional microdomains in G-protein-coupled receptors. The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor
-
Ballesteros J, Kitanovic S, Guarnieri F, Davies P, Fromme BJ, Konvicka K, Chi L, Millar RP, Davidson JS, Weinstein H et al. (1998) Functional microdomains in G-protein-coupled receptors. The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor. J Biol Chem 273:10445-10453.
-
(1998)
J Biol Chem
, vol.273
, pp. 10445-10453
-
-
Ballesteros, J.1
Kitanovic, S.2
Guarnieri, F.3
Davies, P.4
Fromme, B.J.5
Konvicka, K.6
Chi, L.7
Millar, R.P.8
Davidson, J.S.9
Weinstein, H.10
-
4
-
-
0028180127
-
Constitutively active 5-hydroxy tryptamine receptors reveal novel inverse agonist activity of receptor ligands
-
Barker EL, Westphal RS, Schmidt D, and Sanders-Bush E (1994) Constitutively active 5-hydroxy tryptamine receptors reveal novel inverse agonist activity of receptor ligands. J Biol Chem 269:11687-11690.
-
(1994)
J Biol Chem
, vol.269
, pp. 11687-11690
-
-
Barker, E.L.1
Westphal, R.S.2
Schmidt, D.3
Sanders-Bush, E.4
-
5
-
-
0029059732
-
Mapping of single amino acid residues required for selective activation of Gq/11 by the m3 muscarinic acetylcholine receptor
-
Blin N, Yun J, and Wess J (1995) Mapping of single amino acid residues required for selective activation of Gq/11 by the m3 muscarinic acetylcholine receptor. J Biol Chem 270:17741-17748.
-
(1995)
J Biol Chem
, vol.270
, pp. 17741-17748
-
-
Blin, N.1
Yun, J.2
Wess, J.3
-
6
-
-
0034667960
-
Introduction of C3 exoenzyme into cultured endothelium by lipofectamine
-
Borbiev T, Nurmukhambetova S, Liu F, Verin AD, and Garcia JG (2000) Introduction of C3 exoenzyme into cultured endothelium by lipofectamine. Anal Biochem 285:260-264.
-
(2000)
Anal Biochem
, vol.285
, pp. 260-264
-
-
Borbiev, T.1
Nurmukhambetova, S.2
Liu, F.3
Verin, A.D.4
Garcia, J.G.5
-
7
-
-
0030916712
-
Regulation of serotonin-2C receptor G-protein coupling by RNA editing
-
Burns CM, Chu H, Rueter SM, Hutchinson LK, Canton H, Sanders-Bush E, and Emeson RB (1997) Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature (Lond) 387:303-308.
-
(1997)
Nature (Lond)
, vol.387
, pp. 303-308
-
-
Burns, C.M.1
Chu, H.2
Rueter, S.M.3
Hutchinson, L.K.4
Canton, H.5
Sanders-Bush, E.6
Emeson, R.B.7
-
8
-
-
0032544633
-
The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling
-
Burstein ES, Spalding TA, and Brann MR (1998) The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling. J Biol Chem 273:24322-24327.
-
(1998)
J Biol Chem
, vol.273
, pp. 24322-24327
-
-
Burstein, E.S.1
Spalding, T.A.2
Brann, M.R.3
-
9
-
-
0034629513
-
Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells
-
Chang M, Zhang L, Tam JP, and Sanders-Bush E (2000a) Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells. J Biol Chem 275:7021-7029.
-
(2000)
J Biol Chem
, vol.275
, pp. 7021-7029
-
-
Chang, M.1
Zhang, L.2
Tam, J.P.3
Sanders-Bush, E.4
-
10
-
-
84927641625
-
Dissecting intracellular signaling pathways with membrane-permeable peptides
-
Chang MS, Tam JP, and Sanders-Bush E (2000b) Dissecting intracellular signaling pathways with membrane-permeable peptides. Sci STKE 2000:PL1.
-
(2000)
Sci STKE
, vol.2000
-
-
Chang, M.S.1
Tam, J.P.2
Sanders-Bush, E.3
-
11
-
-
0032775007
-
Regulation of phospholipase D
-
Exton JH (1999) Regulation of phospholipase D. Biochim Biophys Acta 1439:121-133.
-
(1999)
Biochim Biophys Acta
, vol.1439
, pp. 121-133
-
-
Exton, J.H.1
-
12
-
-
0037201951
-
Regulation of phospholipase D
-
Exton JH (2002) Regulation of phospholipase D. FEBS Lett 531:58-61.
-
(2002)
FEBS Lett
, vol.531
, pp. 58-61
-
-
Exton, J.H.1
-
13
-
-
0032840122
-
Messenger RNA editing of the human serotonin 5-HT2C receptor
-
Fitzgerald LW, Iyer G, Conklin DS, Krause CM, Marshall A, Patterson JP, Tran DP, Jonak GJ, and Hartig PR (1999) Messenger RNA editing of the human serotonin 5-HT2C receptor. Neuropsychopharmacology 21:82S-90S.
-
(1999)
Neuropsychopharmacology
, vol.21
-
-
Fitzgerald, L.W.1
Iyer, G.2
Conklin, D.S.3
Krause, C.M.4
Marshall, A.5
Patterson, J.P.6
Tran, D.P.7
Jonak, G.J.8
Hartig, P.R.9
-
14
-
-
0033580697
-
Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation
-
Gohla A, Offermanns S, Wilkie TM, and Schultz G (1999) Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation. J Biol Chem 274:17901-17907.
-
(1999)
J Biol Chem
, vol.274
, pp. 17901-17907
-
-
Gohla, A.1
Offermanns, S.2
Wilkie, T.M.3
Schultz, G.4
-
15
-
-
0030050977
-
The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins
-
Gomeza J, Joly C, Kuhn R, Knopfel T, Bockaert J, and Pin JP (1996) The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins. J Biol Chem 271:2199-2205.
-
(1996)
J Biol Chem
, vol.271
, pp. 2199-2205
-
-
Gomeza, J.1
Joly, C.2
Kuhn, R.3
Knopfel, T.4
Bockaert, J.5
Pin, J.P.6
-
16
-
-
0037114951
-
Modulation of serotonin 2C receptor editing by sustained changes in serotonergic neurotransmission
-
Gurevich I, Englander MT, Adlersberg M, Siegal NB, and Schmauss C (2002a) Modulation of serotonin 2C receptor editing by sustained changes in serotonergic neurotransmission. J Neurosci 22:10529-10532.
-
(2002)
J Neurosci
, vol.22
, pp. 10529-10532
-
-
Gurevich, I.1
Englander, M.T.2
Adlersberg, M.3
Siegal, N.B.4
Schmauss, C.5
-
17
-
-
0037171846
-
Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims
-
Gurevich I, Tamir H, Arango V, Dwork AJ, Mann JJ, and Schmauss C (2002b) Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims. Neuron 34:349-356.
-
(2002)
Neuron
, vol.34
, pp. 349-356
-
-
Gurevich, I.1
Tamir, H.2
Arango, V.3
Dwork, A.J.4
Mann, J.J.5
Schmauss, C.6
-
18
-
-
0027931146
-
Specific peptide probes for G-protein interactions with receptors
-
Hamm HE and Rarick HM (1994) Specific peptide probes for G-protein interactions with receptors. Methods Enzymol 237:423-436.
-
(1994)
Methods Enzymol
, vol.237
, pp. 423-436
-
-
Hamm, H.E.1
Rarick, H.M.2
-
19
-
-
0032589301
-
Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: Implications for serotonergic signal transduction
-
Herrick-Davis K, Grinde E, and Niswender CM (1999) Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction. J Neurochem 73:1711-1717.
-
(1999)
J Neurochem
, vol.73
, pp. 1711-1717
-
-
Herrick-Davis, K.1
Grinde, E.2
Niswender, C.M.3
-
20
-
-
0031019308
-
Role of Rho family proteins in phospholipase D activation by growth factors
-
Hess JA, Ross AH, Qiu RG, Symons M, and Exton JH (1997) Role of Rho family proteins in phospholipase D activation by growth factors. J Biol Chem 272:1615-1620.
-
(1997)
J Biol Chem
, vol.272
, pp. 1615-1620
-
-
Hess, J.A.1
Ross, A.H.2
Qiu, R.G.3
Symons, M.4
Exton, J.H.5
-
21
-
-
0030895863
-
Mutations in the second cytoplasmic loop of the rat parathyroid hormone (PTH)/PTH-related protein receptor result in selective loss of PTH-stimulated phospholipase C activity
-
Iida-Klein A, Guo J, Takemura M, Drake MT, Potts JT Jr, Abou-Samra A, Bringhurst FR, and Segre GV (1997) Mutations in the second cytoplasmic loop of the rat parathyroid hormone (PTH)/PTH-related protein receptor result in selective loss of PTH-stimulated phospholipase C activity. J Biol Chem 272:6882-6889.
-
(1997)
J Biol Chem
, vol.272
, pp. 6882-6889
-
-
Iida-Klein, A.1
Guo, J.2
Takemura, M.3
Drake, M.T.4
Potts Jr., J.T.5
Abou-Samra, A.6
Bringhurst, F.R.7
Segre, G.V.8
-
22
-
-
0029991991
-
Different single receptor domains determine the distinct G protein coupling profiles of members of the vasopressin receptor family
-
Liu J and Wess J (1996) Different single receptor domains determine the distinct G protein coupling profiles of members of the vasopressin receptor family. J Biol Chem 271:8772-8778.
-
(1996)
J Biol Chem
, vol.271
, pp. 8772-8778
-
-
Liu, J.1
Wess, J.2
-
23
-
-
0033578621
-
A rho exchange factor mediates thrombin and Galpha(12)-induced cytoskeletal responses
-
Majumdar M, Seasholtz TM, Buckmaster C, Toksoz D, and Brown JH (1999) A rho exchange factor mediates thrombin and Galpha(12)-induced cytoskeletal responses. J Biol Chem 274:26815-26821.
-
(1999)
J Biol Chem
, vol.274
, pp. 26815-26821
-
-
Majumdar, M.1
Seasholtz, T.M.2
Buckmaster, C.3
Toksoz, D.4
Brown, J.H.5
-
24
-
-
16844366239
-
Evidence for Rho-mediated agonist stimulation of phospholipase D in rat1 fibroblasts. Effects of Clostridium botulinum C3 exoenzyme
-
Malcolm KC, Elliott CM, and Exton JH (1996) Evidence for Rho-mediated agonist stimulation of phospholipase D in rat1 fibroblasts. Effects of Clostridium botulinum C3 exoenzyme. J Biol Chem 271:13135-13139.
-
(1996)
J Biol Chem
, vol.271
, pp. 13135-13139
-
-
Malcolm, K.C.1
Elliott, C.M.2
Exton, J.H.3
-
25
-
-
0027999909
-
Activation of rat liver phospholipase D by the small GTP-binding protein RhoA
-
Malcolm KC, Ross AH, Qiu RG, Symons M, and Exton JH (1994) Activation of rat liver phospholipase D by the small GTP-binding protein RhoA. J Biol Chem 269:25951-25954.
-
(1994)
J Biol Chem
, vol.269
, pp. 25951-25954
-
-
Malcolm, K.C.1
Ross, A.H.2
Qiu, R.G.3
Symons, M.4
Exton, J.H.5
-
26
-
-
0036892263
-
Phospholipase D activation by endogenous 5-hydroxytryptamine 2C receptors is mediated by Galpha13 and pertussis toxin-insensitive Gbetagamma subunits
-
McGrew L, Chang MS, and Sanders-Bush E (2002) Phospholipase D activation by endogenous 5-hydroxytryptamine 2C receptors is mediated by Galpha13 and pertussis toxin-insensitive Gbetagamma subunits. Mol Pharmacol 62:1339-1343.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 1339-1343
-
-
McGrew, L.1
Chang, M.S.2
Sanders-Bush, E.3
-
27
-
-
0345131659
-
Serotonin (5-HT)2C receptors tonically inhibit dopamine (DA) and noradrenaline (NA), but not 5-HT, release in the frontal cortex in vivo
-
Millan MJ, Dekeyne A, and Gobert A (1998) Serotonin (5-HT)2C receptors tonically inhibit dopamine (DA) and noradrenaline (NA), but not 5-HT, release in the frontal cortex in vivo. Neuropharmacology 37:953-955.
-
(1998)
Neuropharmacology
, vol.37
, pp. 953-955
-
-
Millan, M.J.1
Dekeyne, A.2
Gobert, A.3
-
28
-
-
0033515573
-
RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity
-
Niswender CM, Copeland SC, Herrick-Davis K, Emeson RB, and Sanders-Bush E (1999) RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity. J Biol Chem 274:9472-9478.
-
(1999)
J Biol Chem
, vol.274
, pp. 9472-9478
-
-
Niswender, C.M.1
Copeland, S.C.2
Herrick-Davis, K.3
Emeson, R.B.4
Sanders-Bush, E.5
-
29
-
-
0035085519
-
RNA editing of the human serotonin 5-HT2C receptor: Alterations in suicide and implications for serotonergic pharmacotherapy
-
Niswender CM, Herrick-Davis K, Dilley GE, Meltzer HY, Overholser JC, Stockmeier CA, Emeson RB, and Sanders-Bush E (2001) RNA editing of the human serotonin 5-HT2C receptor: alterations in suicide and implications for serotonergic pharmacotherapy. Neuropsychopharmacology 24:478-491.
-
(2001)
Neuropsychopharmacology
, vol.24
, pp. 478-491
-
-
Niswender, C.M.1
Herrick-Davis, K.2
Dilley, G.E.3
Meltzer, H.Y.4
Overholser, J.C.5
Stockmeier, C.A.6
Emeson, R.B.7
Sanders-Bush, E.8
-
30
-
-
0002264575
-
Identification and characterization of RNA editing events within the 5-HT2C receptor
-
Niswender CM, Sanders-Bush E, and Emeson RB (1998) Identification and characterization of RNA editing events within the 5-HT2C receptor. Ann N Y Acad Sci 861:38-48.
-
(1998)
Ann N Y Acad Sci
, vol.861
, pp. 38-48
-
-
Niswender, C.M.1
Sanders-Bush, E.2
Emeson, R.B.3
-
31
-
-
0036008435
-
5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum
-
Porras G, Di Matteo V, Fracasso C, Lucas G, De Deurwaerdere P, Caccia S, Esposito E, and Spampinato U (2002) 5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum. Neuropsychopharmacology 26:311-324.
-
(2002)
Neuropsychopharmacology
, vol.26
, pp. 311-324
-
-
Porras, G.1
Di Matteo, V.2
Fracasso, C.3
Lucas, G.4
De Deurwaerdere, P.5
Caccia, S.6
Esposito, E.7
Spampinato, U.8
-
32
-
-
0033798357
-
RNA editing of the human serotonin 5-HT(2C) receptor delays agonist-stimulated calcium release
-
Price RD and Sanders-Bush E (2000) RNA editing of the human serotonin 5-HT(2C) receptor delays agonist-stimulated calcium release. Mol Pharmacol 58:859-862.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 859-862
-
-
Price, R.D.1
Sanders-Bush, E.2
-
33
-
-
0035977070
-
RNA editing of the human serotonin 5-HT2C receptor alters receptor-mediated activation of G13 protein
-
Price RD, Weiner DM, Chang MS, and Sanders-Bush E (2001) RNA editing of the human serotonin 5-HT2C receptor alters receptor-mediated activation of G13 protein. J Biol Chem 276:44663-44668.
-
(2001)
J Biol Chem
, vol.276
, pp. 44663-44668
-
-
Price, R.D.1
Weiner, D.M.2
Chang, M.S.3
Sanders-Bush, E.4
-
34
-
-
0029889591
-
Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain
-
Reid T, Furuyashiki T, Ishizaki T, Watanabe G, Watanabe N, Fujisawa K, Morii N, Madaule P, and Narumiya S (1996) Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain. J Biol Chem 271:13556-13560.
-
(1996)
J Biol Chem
, vol.271
, pp. 13556-13560
-
-
Reid, T.1
Furuyashiki, T.2
Ishizaki, T.3
Watanabe, G.4
Watanabe, N.5
Fujisawa, K.6
Morii, N.7
Madaule, P.8
Narumiya, S.9
-
35
-
-
0034973295
-
RNA editing of the 5-HT2C receptor is reduced in schizophrenia
-
Sodhi M, Burnet P, Makoff A, Kerwin R, and Harrison P (2001) RNA editing of the 5-HT2C receptor is reduced in schizophrenia. Mol Psychiatry 6:373-379.
-
(2001)
Mol Psychiatry
, vol.6
, pp. 373-379
-
-
Sodhi, M.1
Burnet, P.2
Makoff, A.3
Kerwin, R.4
Harrison, P.5
-
36
-
-
0028592603
-
Peptides as probes for G protein signal transduction
-
Taylor JM and Neubig RR (1994) Peptides as probes for G protein signal transduction. Cell Signal 6:841-849.
-
(1994)
Cell Signal
, vol.6
, pp. 841-849
-
-
Taylor, J.M.1
Neubig, R.R.2
-
37
-
-
0031002654
-
The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors. Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors
-
Verrall S, Ishii M, Chen M, Wang L, Tram T, and Coughlin SR (1997) The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors. Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors. J Biol Chem 272: 6898-6902.
-
(1997)
J Biol Chem
, vol.272
, pp. 6898-6902
-
-
Verrall, S.1
Ishii, M.2
Chen, M.3
Wang, L.4
Tram, T.5
Coughlin, S.R.6
|