-
1
-
-
0346599403
-
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
-
Finnish-German, A. C., An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nat. Genet. 1997. 17: 399-403.
-
(1997)
Nat. Genet.
, vol.17
, pp. 399-403
-
-
Finnish-German, A.C.1
-
2
-
-
16944367194
-
Positional cloning of the APECED gene
-
Nagamine, K., Peterson, P., Scott, H. S., Kudoh, J., Minoshima, S., Heino, M., Krohn, K. J. et al., Positional cloning of the APECED gene. Nat. Genet. 1997. 17: 393-398.
-
(1997)
Nat. Genet.
, vol.17
, pp. 393-398
-
-
Nagamine, K.1
Peterson, P.2
Scott, H.S.3
Kudoh, J.4
Minoshima, S.5
Heino, M.6
Krohn, K.J.7
-
3
-
-
23844558032
-
The cellular mechanism of Aire control of T cell tolerance [see comment]
-
Anderson, M. S., Venanzi, E. S., Chen, Z., Berzins, S. P., Benoist, C. and Mathis, D., The cellular mechanism of Aire control of T cell tolerance [see comment]. Immunity 2005. 23: 227-239.
-
(2005)
Immunity
, vol.23
, pp. 227-239
-
-
Anderson, M.S.1
Venanzi, E.S.2
Chen, Z.3
Berzins, S.P.4
Benoist, C.5
Mathis, D.6
-
4
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson, M. S., Venanzi, E. S., Klein, L., Chen, Z., Berzins, S. P., Turley, S. J., von Boehmer, H. et al., Projection of an immunological self shadow within the thymus by the aire protein. Science 2002. 298: 1395-1401.
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
Venanzi, E.S.2
Klein, L.3
Chen, Z.4
Berzins, S.P.5
Turley, S.J.6
von Boehmer, H.7
-
5
-
-
4544258485
-
Self-representation in the thymus: an extended view
-
Kyewski, B. and Derbinski, J., Self-representation in the thymus: an extended view. Nat. Rev. Immunol. 2004. 4: 688-698.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 688-698
-
-
Kyewski, B.1
Derbinski, J.2
-
6
-
-
22344449972
-
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels [see comment]
-
Derbinski, J., Gabler, J., Brors, B., Tierling, S., Jonnakuty, S., Hergenhahn, M., Peltonen, L. et al., Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels [see comment]. J. Exp. Med. 2005. 202: 33-45.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 33-45
-
-
Derbinski, J.1
Gabler, J.2
Brors, B.3
Tierling, S.4
Jonnakuty, S.5
Hergenhahn, M.6
Peltonen, L.7
-
7
-
-
0942288397
-
Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters
-
Gotter, J., Brors, B., Hergenhahn, M. and Kyewski, B., Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters. J. Exp. Med. 2004. 199: 155-166.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 155-166
-
-
Gotter, J.1
Brors, B.2
Hergenhahn, M.3
Kyewski, B.4
-
8
-
-
77952312735
-
Estimating the proportion of microarray probes expressed in an RNA sample
-
Shi, W., de Graaf, C., Kinkel, S. A., Achtman, A., Baldwin, T., Schofield, L., Scott, H. S. et al., Estimating the proportion of microarray probes expressed in an RNA sample. Nucleic Acids Res. 2009. 38: 2168-2176.
-
(2009)
Nucleic Acids Res.
, vol.38
, pp. 2168-2176
-
-
Shi, W.1
de Graaf, C.2
Kinkel, S.A.3
Achtman, A.4
Baldwin, T.5
Schofield, L.6
Scott, H.S.7
-
9
-
-
44849114330
-
A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery
-
Hubert, F. X., Kinkel, S. A., Webster, K. E., Cannon, P., Crewther, P. E., Proeitto, A. I., Wu, L. et al., A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery. J. Immunol. 2008. 180: 3824-3832.
-
(2008)
J. Immunol.
, vol.180
, pp. 3824-3832
-
-
Hubert, F.X.1
Kinkel, S.A.2
Webster, K.E.3
Cannon, P.4
Crewther, P.E.5
Proeitto, A.I.6
Wu, L.7
-
10
-
-
77749279470
-
Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells
-
Poliani, P. L., Kisand, K., Marrella, V., Ravanini, M., Notarangelo, L. D., Villa, A., Peterson, P. et al., Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells. Am. J. Pathol. 2010. 176: 1104-1112.
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 1104-1112
-
-
Poliani, P.L.1
Kisand, K.2
Marrella, V.3
Ravanini, M.4
Notarangelo, L.D.5
Villa, A.6
Peterson, P.7
-
11
-
-
0034662906
-
Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
-
Zuklys, S., Balciunaite, G., Agarwal, A., Fasler-Kan, E., Palmer, E. and Hollander, G. A., Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J. Immunol. 2000. 165: 1976-1983.
-
(2000)
J. Immunol.
, vol.165
, pp. 1976-1983
-
-
Zuklys, S.1
Balciunaite, G.2
Agarwal, A.3
Fasler-Kan, E.4
Palmer, E.5
Hollander, G.A.6
-
12
-
-
1142311548
-
A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues
-
Adamson, K. A., Pearce, S. H., lamb, J. R., Seckl, J. R. and Howie, S. E., A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues. J. Pathol. 2004. 202: 180-187.
-
(2004)
J. Pathol.
, vol.202
, pp. 180-187
-
-
Adamson, K.A.1
Pearce, S.H.2
lamb, J.R.3
Seckl, J.R.4
Howie, S.E.5
-
13
-
-
49449093723
-
Deletional tolerance mediated by extrathymic Aire-expressing cells
-
Gardner, J. M., Devoss, J. J., Friedman, R. S., Wong, D. J., Tan, Y. X., Zhou, X., Johannes, K. P. et al., Deletional tolerance mediated by extrathymic Aire-expressing cells. Science 2008. 321: 843-847.
-
(2008)
Science
, vol.321
, pp. 843-847
-
-
Gardner, J.M.1
Devoss, J.J.2
Friedman, R.S.3
Wong, D.J.4
Tan, Y.X.5
Zhou, X.6
Johannes, K.P.7
-
14
-
-
33747091587
-
Expression profiling of autoimmune regulator AIRE mRNA in a comprehensive set of human normal and neoplastic tissues
-
Klamp, T., Sahin, U., Kyewski, B., Schwendemann, J., Dhaene, K. and Tureci, O., Expression profiling of autoimmune regulator AIRE mRNA in a comprehensive set of human normal and neoplastic tissues. Immunol. Lett. 2006. 106: 172-179.
-
(2006)
Immunol. Lett.
, vol.106
, pp. 172-179
-
-
Klamp, T.1
Sahin, U.2
Kyewski, B.3
Schwendemann, J.4
Dhaene, K.5
Tureci, O.6
-
15
-
-
40649101249
-
Expression of Aire in thymocytes and peripheral lymphocytes
-
Suzuki, E., Kobayashi, Y., Kawano, O., Endo, K., Haneda, H., Yukiue, H., Sasaki, H. et al., Expression of Aire in thymocytes and peripheral lymphocytes. Autoimmunity 2008. 41: 133-139.
-
(2008)
Autoimmunity
, vol.41
, pp. 133-139
-
-
Suzuki, E.1
Kobayashi, Y.2
Kawano, O.3
Endo, K.4
Haneda, H.5
Yukiue, H.6
Sasaki, H.7
-
16
-
-
70449492717
-
AIRE in the thymus and beyond
-
Gardner, J. M., Fletcher, A. L., Anderson, M. S. and Turley, S. J., AIRE in the thymus and beyond. Curr. Opin. Immunol. 2009. 21: 582-589.
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 582-589
-
-
Gardner, J.M.1
Fletcher, A.L.2
Anderson, M.S.3
Turley, S.J.4
-
17
-
-
65449133931
-
Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype
-
Hubert, F. X., Kinkel, S. A., Crewther, P. E., Cannon, P. Z., Webster, K. E., Link, M., Uibo, R. et al., Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype. J. Immunol. 2009. 182: 3902-3918.
-
(2009)
J. Immunol.
, vol.182
, pp. 3902-3918
-
-
Hubert, F.X.1
Kinkel, S.A.2
Crewther, P.E.3
Cannon, P.Z.4
Webster, K.E.5
Link, M.6
Uibo, R.7
-
18
-
-
13544262691
-
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice
-
Kuroda, N., Mitani, T., Takeda, N., Ishimaru, N., Arakaki, R., Hayashi, Y., Bando, Y. et al., Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. J. Immunol. 2005. 174: 1862-1870.
-
(2005)
J. Immunol.
, vol.174
, pp. 1862-1870
-
-
Kuroda, N.1
Mitani, T.2
Takeda, N.3
Ishimaru, N.4
Arakaki, R.5
Hayashi, Y.6
Bando, Y.7
-
19
-
-
32944474710
-
Increased antigen presenting cell-mediated T cell activation in mice and patients without the autoimmune regulator
-
Ramsey, C., Hassler, S., Marits, P., Kampe, O., Surh, C. D., Peltonen, L. and Winqvist, O., Increased antigen presenting cell-mediated T cell activation in mice and patients without the autoimmune regulator. Eur. J. Immunol. 2006. 36: 305-317.
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 305-317
-
-
Ramsey, C.1
Hassler, S.2
Marits, P.3
Kampe, O.4
Surh, C.D.5
Peltonen, L.6
Winqvist, O.7
-
20
-
-
56149122264
-
Effector mechanisms of the autoimmune syndrome in murine model of autoimmune polyglandular syndrome type 1
-
DeVoss, J. J., Shum, A. K., Johannes, K. P. A., Lu, W., Krawisz, A. K., Wang, P., Yang, T. et al., Effector mechanisms of the autoimmune syndrome in murine model of autoimmune polyglandular syndrome type 1. J. Immunol. 2008. 181: 4072-4079.
-
(2008)
J. Immunol.
, vol.181
, pp. 4072-4079
-
-
DeVoss, J.J.1
Shum, A.K.2
Johannes, K.P.A.3
Lu, W.4
Krawisz, A.K.5
Wang, P.6
Yang, T.7
-
21
-
-
25144432460
-
Modifier loci condition autoimmunity provoked by Aire deficiency
-
Jiang, W., Anderson, M. S., Bronson, R., Mathis, D. and Benoist, C., Modifier loci condition autoimmunity provoked by Aire deficiency. J. Exp. Med. 2005. 202: 805-815.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 805-815
-
-
Jiang, W.1
Anderson, M.S.2
Bronson, R.3
Mathis, D.4
Benoist, C.5
-
22
-
-
0037383758
-
Aire regulates negative selection of organ-specific T cells
-
Liston, A., Lesage, S., Wilson, J., Peltonen, L. and Goodnow, C. C., Aire regulates negative selection of organ-specific T cells. Nat. Immunol. 2003. 4: 350-354.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 350-354
-
-
Liston, A.1
Lesage, S.2
Wilson, J.3
Peltonen, L.4
Goodnow, C.C.5
-
23
-
-
34548151158
-
An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus
-
Giraud, M., Taubert, R., Vandiedonck, C., Ke, X., Levi-Strauss, M., Pagani, F., Baralle, F. E. et al., An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus. Nature 2007. 448: 934-937.
-
(2007)
Nature
, vol.448
, pp. 934-937
-
-
Giraud, M.1
Taubert, R.2
Vandiedonck, C.3
Ke, X.4
Levi-Strauss, M.5
Pagani, F.6
Baralle, F.E.7
-
24
-
-
27844563909
-
Insulin alleles and autoimmune regulator (AIRE) gene expression both influence insulin expression in the thymus
-
Sabater, L., Ferrer-Francesch, X., Sospedra, M., Caro, P., Juan, M. and Pujol-Borrell, R., Insulin alleles and autoimmune regulator (AIRE) gene expression both influence insulin expression in the thymus. J. Autoimmun. 2005. 25: 312-318.
-
(2005)
J. Autoimmun.
, vol.25
, pp. 312-318
-
-
Sabater, L.1
Ferrer-Francesch, X.2
Sospedra, M.3
Caro, P.4
Juan, M.5
Pujol-Borrell, R.6
-
25
-
-
68949125744
-
Gene therapy and bone marrow stem-cell transfer to treat autoimmune disease
-
Alderuccio, F., Chan, J., Scott, D. W. and Toh, B. H., Gene therapy and bone marrow stem-cell transfer to treat autoimmune disease. Trends Mol. Med. 2009. 15: 344-351.
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 344-351
-
-
Alderuccio, F.1
Chan, J.2
Scott, D.W.3
Toh, B.H.4
-
26
-
-
0028821912
-
Prevention of autoimmune disease by retroviral-mediated gene therapy
-
Ally, B. A., Hawley, T. S., McKall-Faienza, K. J., Kundig, T. M., Oehen, S. U., Pircher, H., Hawley, R. G. et al., Prevention of autoimmune disease by retroviral-mediated gene therapy. J. Immunol. 1995. 155: 5404-5408.
-
(1995)
J. Immunol.
, vol.155
, pp. 5404-5408
-
-
Ally, B.A.1
Hawley, T.S.2
McKall-Faienza, K.J.3
Kundig, T.M.4
Oehen, S.U.5
Pircher, H.6
Hawley, R.G.7
-
27
-
-
50949122634
-
Tolerization of a type 1 allergic response through transplantation of genetically modified hematopoietic stem cells
-
Baranyi, U., Linhart, B., Pilat, N., Gattringer, M., Bagley, J., Muehlbacher, F., Iacomini, J. et al., Tolerization of a type 1 allergic response through transplantation of genetically modified hematopoietic stem cells. J. Immunol. 2008. 180: 8168-8175.
-
(2008)
J. Immunol.
, vol.180
, pp. 8168-8175
-
-
Baranyi, U.1
Linhart, B.2
Pilat, N.3
Gattringer, M.4
Bagley, J.5
Muehlbacher, F.6
Iacomini, J.7
-
28
-
-
28844477590
-
Bone marrow transplantation combined with gene therapy to induce antigen-specific tolerance and ameliorate EAE
-
Xu, B., Haviernik, P., Wolfraim, L. A., Bunting, K. D. and Scott, D. W., Bone marrow transplantation combined with gene therapy to induce antigen-specific tolerance and ameliorate EAE. Mol. Ther. 2006. 13: 42-48.
-
(2006)
Mol. Ther.
, vol.13
, pp. 42-48
-
-
Xu, B.1
Haviernik, P.2
Wolfraim, L.A.3
Bunting, K.D.4
Scott, D.W.5
-
29
-
-
71849087808
-
Transplantation of bone marrow transduced to express self-antigen establishes deletional tolerance and permanently remits autoimmune disease
-
Chan, J., Ban, E. J., Chun, K. H., Wang, B., Backstrom, B. T., Bernard, C., Toh, B. H. et al., Transplantation of bone marrow transduced to express self-antigen establishes deletional tolerance and permanently remits autoimmune disease. J. Immunol. 2008. 181: 7571-7580.
-
(2008)
J. Immunol.
, vol.181
, pp. 7571-7580
-
-
Chan, J.1
Ban, E.J.2
Chun, K.H.3
Wang, B.4
Backstrom, B.T.5
Bernard, C.6
Toh, B.H.7
-
30
-
-
34548285420
-
Modulation of Aire regulates the expression of tissue-restricted antigens
-
Kont, V., Laan, M., Kisand, K., Merits, A., Scott, H. S. and Peterson, P., Modulation of Aire regulates the expression of tissue-restricted antigens. Mol. Immunol. 2008. 45: 25-33.
-
(2008)
Mol. Immunol.
, vol.45
, pp. 25-33
-
-
Kont, V.1
Laan, M.2
Kisand, K.3
Merits, A.4
Scott, H.S.5
Peterson, P.6
-
31
-
-
37549060329
-
AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells
-
Oven, I., Brdickova, N., Kohoutek, J., Vaupotic, T., Narat, M. and Peterlin, B. M., AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells. Mol. Cell Biol. 2007. 27: 8815-8823.
-
(2007)
Mol. Cell Biol.
, vol.27
, pp. 8815-8823
-
-
Oven, I.1
Brdickova, N.2
Kohoutek, J.3
Vaupotic, T.4
Narat, M.5
Peterlin, B.M.6
-
32
-
-
2442595192
-
Aire downregulates multiple molecules that have contradicting immune-enhancing and immune-suppressive functions
-
Sato, K., Sato, U., Tateishi, S., Kubo, K., Horikawa, R., Mimura, T., Yamamoto, K. et al., Aire downregulates multiple molecules that have contradicting immune-enhancing and immune-suppressive functions. Biochem. Biophy. Res. Commun. 2004. 318: 935-940.
-
(2004)
Biochem. Biophy. Res. Commun.
, vol.318
, pp. 935-940
-
-
Sato, K.1
Sato, U.2
Tateishi, S.3
Kubo, K.4
Horikawa, R.5
Mimura, T.6
Yamamoto, K.7
-
33
-
-
5144231380
-
Autoimmune regulator induced changes in the gene expression profile of human monocyte-dendritic cell-lineage
-
Sillanpaa, N., Magureanu, C. G., Murumagi, A., Reinikainen, A., West, A., Manninen, A., Lahti, M. et al., Autoimmune regulator induced changes in the gene expression profile of human monocyte-dendritic cell-lineage. Mol. Immunol. 2004. 41: 1185-1198.
-
(2004)
Mol. Immunol.
, vol.41
, pp. 1185-1198
-
-
Sillanpaa, N.1
Magureanu, C.G.2
Murumagi, A.3
Reinikainen, A.4
West, A.5
Manninen, A.6
Lahti, M.7
-
34
-
-
52949125608
-
Transcriptional impact of Aire varies with cell type
-
Guerau-de-Arellano, M., Mathis, D. and Benoist, C., Transcriptional impact of Aire varies with cell type. Proc. Natl. Acad. Sci. USA 2008. 105: 14011-14016.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 14011-14016
-
-
Guerau-de-Arellano, M.1
Mathis, D.2
Benoist, C.3
-
35
-
-
7244227646
-
Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity
-
Liston, A., Gray, D. H., Lesage, S., Fletcher, A. L., Wilson, J., Webster, K. E., Scott, H. S. et al., Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. J. Exp. Med. 2004. 200: 1015-1026.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1015-1026
-
-
Liston, A.1
Gray, D.H.2
Lesage, S.3
Fletcher, A.L.4
Wilson, J.5
Webster, K.E.6
Scott, H.S.7
-
36
-
-
0035147378
-
Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED)
-
Halonen, M., Pelto-Huikko, M., Eskelin, P., Peltonen, L., Ulmanen, I. and Kolmer, M., Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED). J. Histochem. Cytochem. 2001. 49: 197-208.
-
(2001)
J. Histochem. Cytochem.
, vol.49
, pp. 197-208
-
-
Halonen, M.1
Pelto-Huikko, M.2
Eskelin, P.3
Peltonen, L.4
Ulmanen, I.5
Kolmer, M.6
-
37
-
-
0037115481
-
Systematic mutagenesis of the functional domains of AIRE reveals their role in intracellular targeting
-
Ramsey, C., Bukrinsky, A. and Peltonen, L., Systematic mutagenesis of the functional domains of AIRE reveals their role in intracellular targeting. Hum. Mol. Genet. 2002. 11: 3299-3308.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 3299-3308
-
-
Ramsey, C.1
Bukrinsky, A.2
Peltonen, L.3
-
38
-
-
0032924111
-
AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered sub-cellular distribution of mutants lacking the PHD zinc fingers
-
Rinderle, C., Christensen, H. M., Schweiger, S., Lehrach, H. and Yaspo, M. L., AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered sub-cellular distribution of mutants lacking the PHD zinc fingers. Hum. Mol. Genet. 1999. 8: 277-290.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 277-290
-
-
Rinderle, C.1
Christensen, H.M.2
Schweiger, S.3
Lehrach, H.4
Yaspo, M.L.5
-
39
-
-
34147128054
-
Highly variable expression of tissue-restricted self-antigens in human thymus: implications for self-tolerance and autoimmunity
-
Taubert, R., Schwendemann, J. and Kyewski, B., Highly variable expression of tissue-restricted self-antigens in human thymus: implications for self-tolerance and autoimmunity. Eur. J. Immunol. 2007. 37: 838-848.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 838-848
-
-
Taubert, R.1
Schwendemann, J.2
Kyewski, B.3
-
40
-
-
0037097841
-
Induction of T-cell tolerance to an MHC class I alloantigen by gene therapy
-
Bagley, J., Tian, C., Sachs, D. H. and Iacomini, J., Induction of T-cell tolerance to an MHC class I alloantigen by gene therapy. Blood 2002. 99: 4394-4399.
-
(2002)
Blood
, vol.99
, pp. 4394-4399
-
-
Bagley, J.1
Tian, C.2
Sachs, D.H.3
Iacomini, J.4
-
41
-
-
0031058466
-
Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo
-
Brocker, T., Riedinger, M. and Karjalainen, K., Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo. J. Exp. Med. 1997. 185: 541-550.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 541-550
-
-
Brocker, T.1
Riedinger, M.2
Karjalainen, K.3
-
42
-
-
63449108301
-
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
-
Ohnmacht, C., Pullner, A., King, S. B., Drexler, I., Meier, S., Brocker, T. and Voehringer, D., Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J. Exp. Med. 2009. 206: 549-559.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 549-559
-
-
Ohnmacht, C.1
Pullner, A.2
King, S.B.3
Drexler, I.4
Meier, S.5
Brocker, T.6
Voehringer, D.7
-
43
-
-
33645071052
-
Central tolerance: good but imperfect
-
Gallegos, A. M. and Bevan, M. J., Central tolerance: good but imperfect. Immunol. Rev. 2006. 209: 290-296.
-
(2006)
Immunol. Rev.
, vol.209
, pp. 290-296
-
-
Gallegos, A.M.1
Bevan, M.J.2
-
44
-
-
41549093091
-
Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+T cell tolerance in vivo
-
Luckashenak, N., Schroeder, S., Endt, K., Schmidt, D., Mahnke, K., Bachmann, M. F., Marconi, P. et al., Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+T cell tolerance in vivo. Immunity 2008. 28: 521-532.
-
(2008)
Immunity
, vol.28
, pp. 521-532
-
-
Luckashenak, N.1
Schroeder, S.2
Endt, K.3
Schmidt, D.4
Mahnke, K.5
Bachmann, M.F.6
Marconi, P.7
-
45
-
-
58149311504
-
Lentiviral-mediated transcriptional targeting of dendritic cells for induction of T cell tolerance in vivo
-
Dresch, C., Edelmann, S. L., Marconi, P. and Brocker, T., Lentiviral-mediated transcriptional targeting of dendritic cells for induction of T cell tolerance in vivo. J. Immunol. 2008. 181: 4495-4506.
-
(2008)
J. Immunol.
, vol.181
, pp. 4495-4506
-
-
Dresch, C.1
Edelmann, S.L.2
Marconi, P.3
Brocker, T.4
-
46
-
-
58149376454
-
Dendritic cells in the thymus contribute to T-regulatory cell induction
-
Proietto, A. I., van Dommelen, S., Zhou, P., Rizzitelli, A., D'Amico, A., Steptoe, R. J., Naik, S. H. et al., Dendritic cells in the thymus contribute to T-regulatory cell induction. Proc. Natl. Acad. Sci. USA 2008. 105: 19869-19874.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 19869-19874
-
-
Proietto, A.I.1
van Dommelen, S.2
Zhou, P.3
Rizzitelli, A.4
D'Amico, A.5
Steptoe, R.J.6
Naik, S.H.7
-
47
-
-
18844362882
-
Chromosomal clustering of genes controlled by the aire transcription factor
-
Johnnidis, J. B., Venanzi, E. S., Taxman, D. J., Ting, J. P., Benoist, C. O. and Mathis, D. J., Chromosomal clustering of genes controlled by the aire transcription factor. Proc. Natl. Acad. Sci. USA 2005. 102: 7233-7238.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 7233-7238
-
-
Johnnidis, J.B.1
Venanzi, E.S.2
Taxman, D.J.3
Ting, J.P.4
Benoist, C.O.5
Mathis, D.J.6
-
48
-
-
0033573956
-
Isolation and characterization of the mouse Aire gene
-
Mittaz, L., Rossier, C., Heino, M., Peterson, P., Krohn, K. J., Gos, A., Morris, M. A. et al., Isolation and characterization of the mouse Aire gene. Biochem. Biophys. Res. Commun. 1999. 255: 483-490.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.255
, pp. 483-490
-
-
Mittaz, L.1
Rossier, C.2
Heino, M.3
Peterson, P.4
Krohn, K.J.5
Gos, A.6
Morris, M.A.7
-
49
-
-
0142227052
-
Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics
-
Kitamura, T., Koshino, Y., Shibata, F., Oki, T., Nakajima, H., Nosaka, T. and Kumagai, H., Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics. Exp. Hematol. 2003. 31: 1007-1014.
-
(2003)
Exp. Hematol.
, vol.31
, pp. 1007-1014
-
-
Kitamura, T.1
Koshino, Y.2
Shibata, F.3
Oki, T.4
Nakajima, H.5
Nosaka, T.6
Kumagai, H.7
-
50
-
-
33751247344
-
Transplantation of bone marrow genetically engineered to express proinsulin II protects against autoimmune insulitis in NOD mice
-
Chan, J., Clements, W., Field, J., Lock, P., Yap, F., Toh, B. H. and Alderuccio, F., Transplantation of bone marrow genetically engineered to express proinsulin II protects against autoimmune insulitis in NOD mice. J. Gene. Med. 2006. 8: 1281-1290.
-
(2006)
J. Gene. Med.
, vol.8
, pp. 1281-1290
-
-
Chan, J.1
Clements, W.2
Field, J.3
Lock, P.4
Yap, F.5
Toh, B.H.6
Alderuccio, F.7
-
51
-
-
0036470005
-
Analysis of thymic stromal cell populations using flow cytometry
-
Gray, D. H., Chidgey, A. P. and Boyd, R. L., Analysis of thymic stromal cell populations using flow cytometry. J. Immunol. Methods 2002. 260: 15-28.
-
(2002)
J. Immunol. Methods
, vol.260
, pp. 15-28
-
-
Gray, D.H.1
Chidgey, A.P.2
Boyd, R.L.3
|