-
1
-
-
4544258485
-
Self-representation in the thymus: an extended view
-
Kyewski B., and Derbinski J. Self-representation in the thymus: an extended view. Nat Rev Immunol 4 (2004) 688-698
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 688-698
-
-
Kyewski, B.1
Derbinski, J.2
-
2
-
-
0242491039
-
Negative selection and autoimmunity
-
Ohashi P.S. Negative selection and autoimmunity. Curr Opin Immunol 15 (2003) 668-676
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 668-676
-
-
Ohashi, P.S.1
-
3
-
-
0035171545
-
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
-
Derbinski J., Schulte A., Kyewski B., and Klein L. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat Immunol 2 (2001) 1032-1039
-
(2001)
Nat Immunol
, vol.2
, pp. 1032-1039
-
-
Derbinski, J.1
Schulte, A.2
Kyewski, B.3
Klein, L.4
-
4
-
-
0942288397
-
Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters
-
Gotter J., Brors B., Hergenhahn M., and Kyewski B. Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters. J Exp Med 199 (2004) 155-166
-
(2004)
J Exp Med
, vol.199
, pp. 155-166
-
-
Gotter, J.1
Brors, B.2
Hergenhahn, M.3
Kyewski, B.4
-
5
-
-
22344449972
-
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
-
Derbinski J., Gabler J., Brors B., Tierling S., Jonnakuty S., Hergenhahn M., et al. Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J Exp Med 202 (2005) 33-45
-
(2005)
J Exp Med
, vol.202
, pp. 33-45
-
-
Derbinski, J.1
Gabler, J.2
Brors, B.3
Tierling, S.4
Jonnakuty, S.5
Hergenhahn, M.6
-
6
-
-
16944367194
-
Positional cloning of the APECED gene
-
Nagamine K., Peterson P., Scott H.S., Kudoh J., Minoshima S., Heino M., et al. Positional cloning of the APECED gene. Nat Genet 17 (1997) 393-398
-
(1997)
Nat Genet
, vol.17
, pp. 393-398
-
-
Nagamine, K.1
Peterson, P.2
Scott, H.S.3
Kudoh, J.4
Minoshima, S.5
Heino, M.6
-
7
-
-
0346599403
-
-
The Finnish-German APECED Consortium. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nat Genet 1997;17:399-403.
-
-
-
-
8
-
-
9644281113
-
AIRE and immunological tolerance: insights from the study of autoimmune polyendocrinopathy candidiasis and ectodermal dystrophy
-
Notarangelo L.D., Mazza C., Forino C., Mazzolari E., and Buzi F. AIRE and immunological tolerance: insights from the study of autoimmune polyendocrinopathy candidiasis and ectodermal dystrophy. Curr Opin Allergy Clin Immunol 4 (2004) 491-496
-
(2004)
Curr Opin Allergy Clin Immunol
, vol.4
, pp. 491-496
-
-
Notarangelo, L.D.1
Mazza, C.2
Forino, C.3
Mazzolari, E.4
Buzi, F.5
-
9
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson M.S., Venanzi E.S., Klein L., Chen Z., Berzins S.P., Turley S.J., et al. Projection of an immunological self shadow within the thymus by the aire protein. Science 298 (2002) 1395-1401
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
Venanzi, E.S.2
Klein, L.3
Chen, Z.4
Berzins, S.P.5
Turley, S.J.6
-
11
-
-
0037084784
-
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
-
Ramsey C., Winqvist O., Puhakka L., Halonen M., Moro A., Kampe O., et al. Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum Mol Genet 11 (2002) 397-409
-
(2002)
Hum Mol Genet
, vol.11
, pp. 397-409
-
-
Ramsey, C.1
Winqvist, O.2
Puhakka, L.3
Halonen, M.4
Moro, A.5
Kampe, O.6
-
12
-
-
23844558032
-
The cellular mechanism of Aire control of T cell tolerance
-
Anderson M.S., Venanzi E.S., Chen Z., Berzins S.P., Benoist C., and Mathis D. The cellular mechanism of Aire control of T cell tolerance. Immunity 23 (2005) 227-239
-
(2005)
Immunity
, vol.23
, pp. 227-239
-
-
Anderson, M.S.1
Venanzi, E.S.2
Chen, Z.3
Berzins, S.P.4
Benoist, C.5
Mathis, D.6
-
13
-
-
13544262691
-
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice
-
Kuroda N., Mitani T., Takeda N., Ishimaru N., Arakaki R., Hayashi Y., et al. Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. J Immunol 174 (2005) 1862-1870
-
(2005)
J Immunol
, vol.174
, pp. 1862-1870
-
-
Kuroda, N.1
Mitani, T.2
Takeda, N.3
Ishimaru, N.4
Arakaki, R.5
Hayashi, Y.6
-
14
-
-
0038486459
-
Localization of the APECED protein in distinct nuclear structures
-
Bjorses P., Pelto-Huikko M., Kaukonen J., Aaltonen J., Peltonen L., and Ulmanen I. Localization of the APECED protein in distinct nuclear structures. Hum Mol Genet 8 (1999) 259-266
-
(1999)
Hum Mol Genet
, vol.8
, pp. 259-266
-
-
Bjorses, P.1
Pelto-Huikko, M.2
Kaukonen, J.3
Aaltonen, J.4
Peltonen, L.5
Ulmanen, I.6
-
15
-
-
0033590981
-
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla
-
Heino M., Peterson P., Kudoh J., Nagamine K., Lagerstedt A., Ovod V., et al. Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. Biochem Biophys Res Commun 257 (1999) 821-825
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 821-825
-
-
Heino, M.1
Peterson, P.2
Kudoh, J.3
Nagamine, K.4
Lagerstedt, A.5
Ovod, V.6
-
16
-
-
0036498116
-
Expression of AIRE gene in peripheral monocyte/dendritic cell lineage
-
Kogawa K., Nagafuchi S., Katsuta H., Kudoh J., Tamiya S., Sakai Y., et al. Expression of AIRE gene in peripheral monocyte/dendritic cell lineage. Immunol Lett 80 (2002) 195-198
-
(2002)
Immunol Lett
, vol.80
, pp. 195-198
-
-
Kogawa, K.1
Nagafuchi, S.2
Katsuta, H.3
Kudoh, J.4
Tamiya, S.5
Sakai, Y.6
-
17
-
-
0032924111
-
AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered sub-cellular distribution of mutants lacking the PHD zinc fingers
-
Rinderle C., Christensen H.M., Schweiger S., Lehrach H., and Yaspo M.L. AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered sub-cellular distribution of mutants lacking the PHD zinc fingers. Hum Mol Genet 8 (1999) 277-290
-
(1999)
Hum Mol Genet
, vol.8
, pp. 277-290
-
-
Rinderle, C.1
Christensen, H.M.2
Schweiger, S.3
Lehrach, H.4
Yaspo, M.L.5
-
18
-
-
23144464171
-
Cancer/testis antigens, gametogenesis and cancer
-
Simpson A.J., Caballero O.L., Jungbluth A., Chen Y.T., and Old L.J. Cancer/testis antigens, gametogenesis and cancer. Nat Rev Cancer 5 (2005) 615-625
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 615-625
-
-
Simpson, A.J.1
Caballero, O.L.2
Jungbluth, A.3
Chen, Y.T.4
Old, L.J.5
-
19
-
-
17544385823
-
Characterization of regulatory elements and methylation pattern of the autoimmune regulator (AIRE) promoter
-
Murumagi A., Vahamurto P., and Peterson P. Characterization of regulatory elements and methylation pattern of the autoimmune regulator (AIRE) promoter. J Biol Chem 278 (2003) 19784-19790
-
(2003)
J Biol Chem
, vol.278
, pp. 19784-19790
-
-
Murumagi, A.1
Vahamurto, P.2
Peterson, P.3
-
20
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
Rhee I., Bachman K.E., Park B.H., Jair K.W., Yen R.W., Schuebel K.E., et al. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 416 (2002) 552-556
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.W.4
Yen, R.W.5
Schuebel, K.E.6
-
21
-
-
12344270322
-
Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes
-
de Kok J.B., Roelofs R.W., Giesendorf B.A., Pennings J.L., Waas E.T., Feuth T., et al. Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes. Lab Invest 85 (2005) 154-159
-
(2005)
Lab Invest
, vol.85
, pp. 154-159
-
-
de Kok, J.B.1
Roelofs, R.W.2
Giesendorf, B.A.3
Pennings, J.L.4
Waas, E.T.5
Feuth, T.6
-
22
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25 (2001) 402-408
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
23
-
-
23444446431
-
DNA methylation in epigenetic control of gene expression
-
Razin A., and Kantor B. DNA methylation in epigenetic control of gene expression. Prog Mol Subcell Biol 38 (2005) 151-167
-
(2005)
Prog Mol Subcell Biol
, vol.38
, pp. 151-167
-
-
Razin, A.1
Kantor, B.2
-
24
-
-
16244367143
-
AIRE and APECED: molecular insights into an autoimmune disease
-
Villasenor J., Benoist C., and Mathis D. AIRE and APECED: molecular insights into an autoimmune disease. Immunol Rev 204 (2005) 156-164
-
(2005)
Immunol Rev
, vol.204
, pp. 156-164
-
-
Villasenor, J.1
Benoist, C.2
Mathis, D.3
-
25
-
-
5144231380
-
Autoimmune regulator induced changes in the gene expression profile of human monocyte-dendritic cell-lineage
-
Sillanpaa N., Magureanu C.G., Murumagi A., Reinikainen A., West A., Manninen A., et al. Autoimmune regulator induced changes in the gene expression profile of human monocyte-dendritic cell-lineage. Mol Immunol 41 (2004) 1185-1198
-
(2004)
Mol Immunol
, vol.41
, pp. 1185-1198
-
-
Sillanpaa, N.1
Magureanu, C.G.2
Murumagi, A.3
Reinikainen, A.4
West, A.5
Manninen, A.6
-
26
-
-
7244227646
-
Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity
-
Liston A., Gray D.H., Lesage S., Fletcher A.L., Wilson J., Webster K.E., et al. Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. J Exp Med 200 (2004) 1015-1026
-
(2004)
J Exp Med
, vol.200
, pp. 1015-1026
-
-
Liston, A.1
Gray, D.H.2
Lesage, S.3
Fletcher, A.L.4
Wilson, J.5
Webster, K.E.6
-
27
-
-
0035234557
-
Genomic imprinting: parental influence on the genome
-
Reik W., and Walter J. Genomic imprinting: parental influence on the genome. Nat Rev Genet 2 (2001) 21-32
-
(2001)
Nat Rev Genet
, vol.2
, pp. 21-32
-
-
Reik, W.1
Walter, J.2
-
28
-
-
4344711733
-
Frequent nonrandom activation of germ-line genes in human cancer
-
Koslowski M., Bell C., Seitz G., Lehr H.A., Roemer K., Muntefering H., et al. Frequent nonrandom activation of germ-line genes in human cancer. Cancer Res 64 (2004) 5988-5993
-
(2004)
Cancer Res
, vol.64
, pp. 5988-5993
-
-
Koslowski, M.1
Bell, C.2
Seitz, G.3
Lehr, H.A.4
Roemer, K.5
Muntefering, H.6
-
29
-
-
0036733675
-
Chromatin modification and epigenetic reprogramming in mammalian development
-
Li E. Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet 3 (2002) 662-673
-
(2002)
Nat Rev Genet
, vol.3
, pp. 662-673
-
-
Li, E.1
-
30
-
-
14744267496
-
Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression
-
Song F., Smith J.F., Kimura M.T., Morrow A.D., Matsuyama T., Nagase H., et al. Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression. Proc Natl Acad Sci USA 102 (2005) 3336-3341
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3336-3341
-
-
Song, F.1
Smith, J.F.2
Kimura, M.T.3
Morrow, A.D.4
Matsuyama, T.5
Nagase, H.6
-
31
-
-
0028315867
-
Role of DNA methylation in the regulation of transcription
-
Eden S., and Cedar H. Role of DNA methylation in the regulation of transcription. Curr Opin Genet Dev 4 (1994) 255-259
-
(1994)
Curr Opin Genet Dev
, vol.4
, pp. 255-259
-
-
Eden, S.1
Cedar, H.2
-
32
-
-
0032694084
-
DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter
-
De Smet C., Lurquin C., Lethe B., Martelange V., and Boon T. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. Mol Cell Biol 19 (1999) 7327-7335
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7327-7335
-
-
De Smet, C.1
Lurquin, C.2
Lethe, B.3
Martelange, V.4
Boon, T.5
-
33
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
Jaenisch R., and Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 33 Suppl (2003) 245-254
-
(2003)
Nat Genet
, vol.33
, Issue.SUPPL
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
34
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 16 (2002) 6-21
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
|