p16INK4a-mediated suppression of telomerase in normal and malignant human breast cells

Aging Cell

Volumn 9, Issue 5, 2010, Pages 736-746

  Bazarov, Alexey V ^a   Van Sluis, Marjolein ^b   Hines, William C ^b   Bassett, Ekaterina ^b   Beliveau, Alain ^b   Campeau, Eric ^b   Mukhopadhyay, Rituparna ^b   Lee, Won Jae ^b   Melodyev, Sonya ^b   Zaslavsky, Yuri ^a   Lee, Leonard ^c   Rodier, Francis ^b,d   Chicas, Agustin ^e   Lowe, Scott W ^e   Benhattar, Jean ^f   Ren, Bing ^c   Campisi, Judith ^b,d   Yaswen, Paul ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^e University of Lausanne ^*  (United States)

^f UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Heterochromatin; Histone methylation; hTERT; INK4a; Senescence

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; HISTONE H3; PROTEIN P16; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; BREAST CELL; CELL CYCLE PROGRESSION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE REPRESSION; HUMAN; HUMAN CELL; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROCESSING;

BREAST; BREAST NEOPLASMS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; EPITHELIAL CELLS; GENE SILENCING; HISTONES; HUMANS; METHYLATION; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TELOMERASE;

EID: 78349273669     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2010.00599.x     Document Type: Article

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