Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis

Journal of Mammary Gland Biology and Neoplasia

Volumn 9, Issue 3, 2004, Pages 263-274

  Tlsty, Thea D ^a   Crawford, Yongping G ^a   Holst, Charles R ^a,b   Fordyce, Colleen A ^a   Zhang, Jianmin ^a   McDermott, Kimberly ^a   Kozakiewicz, Krystyna ^a   Gauthier, Mona L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GENENTECH INC   (United States)

Author keywords

Breast carcinogenesis; COX 2; Genomic instability; Human mammary epithelial cells; p16INK4a hypermethylation

Indexed keywords

BETA GALACTOSIDASE; BRCA1 PROTEIN; CYCLOOXYGENASE 2; CYTOKERATIN; IMATINIB; PROTEIN MLH1; PROTEIN P14ARF; PROTEIN P15; PROTEIN P16; PROTEIN P19; RETINOBLASTOMA PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UVOMORULIN; VON HIPPEL LINDAU PROTEIN;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; BREAST CELL; BREAST EPITHELIUM; BREAST HYPERPLASIA; CANCER GROWTH; CELL AGING; CELL CULTURE; CELL SUBPOPULATION; CHROMOSOME ABERRATION; DISEASE COURSE; DRUG TARGETING; EPIGENETICS; FIBROBLAST; GENE EXPRESSION PROFILING; GENE MUTATION; GENE SEQUENCE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRECANCER; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN METHYLATION; TELOMERE;

BREAST NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; EPIGENESIS, GENETIC; EPITHELIAL CELLS; FEMALE; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC INSTABILITY; HUMANS; MAMMARY GLANDS, HUMAN;

EID: 9144221430     PISSN: 10833021     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:JOMG.0000048773.95897.5f     Document Type: Article

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