Recent advances in the understanding of genetic defects of neutrophil number and function

British Journal of Haematology

Volumn 151, Issue 4, 2010, Pages 312-326

  Bouma, Gerben ^a   Ancliff, Phil J ^b   Thrasher, Adrian J ^a,b   Burns, Siobhan O ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GREAT ORMOND STREET HOSPITAL   (United Kingdom)

Author keywords

Adhesion; Cell migration; Immunodeficiency; Neutropenia; Neutrophil function; Neutrophils; Oxidative burst

Indexed keywords

BETA1 INTEGRIN; CHEMOKINE RECEPTOR CXCR4; CYTOCHROME B 245 ALPHA POLYPEPTIDE; CYTOCHROME B 245 BETA POLYPEPTIDE; FERMITIN FAMILY HOMOLOG 3 PROTEIN; GLUCOSE 6 PHOSPHATASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GROWTH FACTOR INDEPENDENT 1 TRANSCRIPTION REPRESSOR; HCLS1 ASSOCIATED PROTEIN X 1; I KAPPA B KINASE GAMMA; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; LEUKOCYTE ADHESION DEFICIENCY TYPE 1 PROTEIN; LEUKOCYTE ADHESION DEFICIENCY TYPE 2 PROTEIN; LEUKOCYTE ADHESION DEFICIENCY TYPE 3 PROTEIN; LEUKOCYTE ELASTASE; MITOGEN ACTIVATED PROTEIN BINDING PROTEIN INTERACTING PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; MYELOPEROXIDASE; NEUTROPHIL CYTOSOLIC FACTOR; PROTEIN; RAB278A MEMBER RAS ONCOGENE FAMILY PROTEIN; RAS GUANYL RELEASING PROTEIN 2; ROADBLOCK DOMAIN CONTAINING 3 PROTEIN; SOLUTE CARRIER FAMILY 35 MEMBER C1; UNCLASSIFIED DRUG; WISKOTT ALDRICH SYNDROME PROTEIN;

AEROBIC METABOLISM; ARTICLE; CELL DIFFERENTIATION; CHEDIAK HIGASHI SYNDROME; CHRONIC GRANULOMATOUS DISEASE; DISEASE SEVERITY; ENZYME DEFICIENCY; GENE MUTATION; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; GRISCELLI SYNDROME; HUMAN; INFECTION SENSITIVITY; LEUKOCYTE FUNCTION; NEUTROPENIA; NEUTROPHIL COUNT; OCULAR ALBINISM; PHENOTYPE; PRIORITY JOURNAL; PROMYELOCYTE; PROTEIN DEFICIENCY; SEVERE CONGENITAL NEUTROPENIA; WART HYPOGAMMAGLOBULINAEMIA INFECTION AND MYELOKATHEXIS SYNDROME; WISKOTT ALDRICH SYNDROME; X CHROMOSOME LINKED DISORDER;

CELL DIFFERENTIATION; CELL MOVEMENT; CYTOSKELETON; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; NEUTROPENIA; NEUTROPHILS; RESPIRATORY BURST; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 77958527084     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08361.x     Document Type: Article

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