Biochemical and Biological Characterization of a Human Rac2 GTPase Mutant Associated with Phagocytic Immunodeficiency

Journal of Biological Chemistry

Volumn 276, Issue 19, 2001, Pages 15929-15938

  Gu, Yi ^a   Jia, Baoqing ^b   Yang, Feng Chun ^a   D'Souza, Maria ^a   Harris, Chad E ^a   Derrow, Caroline W ^a   Zheng, Yi ^b   Williams, David A ^a,c  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; BLOOD; BONE; CELLS; IMMUNOLOGY; MUTAGENESIS;

APOPTOSIS;

ENZYMES;

FORMYLMETHIONYLLEUCYLPHENYLALANINE; GROWTH FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; L SELECTIN; RAC PROTEIN; RAC1 PROTEIN; RAC2 PROTEIN; SUPEROXIDE; UNCLASSIFIED DRUG; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CHEMOTAXIS; CONTROLLED STUDY; DISSOCIATION; GENE OVEREXPRESSION; GENE TARGETING; HEMATOPOIETIC CELL; HUMAN; IMMUNE DEFICIENCY; IRRADIATION; MOUSE; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; AMINO ACID SUBSTITUTION; ANIMAL; CELL DIVISION; CELL LINE; CYTOLOGY; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; METABOLISM; MOLECULAR CLONING; MOUSE MUTANT; PHENOTYPE; PHYSIOLOGY;

ANIMALIA; MURINAE;

AMINO ACID SUBSTITUTION; ANIMALS; BONE MARROW CELLS; CELL DIVISION; CELL LINE; CELL SURVIVAL; CLONING, MOLECULAR; GTP PHOSPHOHYDROLASES; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; MICE; MICE, KNOCKOUT; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PHAGOCYTOSIS; PHENOTYPE; RAC GTP-BINDING PROTEINS; RECOMBINANT PROTEINS; SUPEROXIDES; TRANSFECTION;

EID: 0035844138     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010445200     Document Type: Article

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