메뉴 건너뛰기




Volumn , Issue , 2007, Pages 507-518

Modulating gene function with peptide nucleic acids (PNA)

Author keywords

[No Author keywords available]

Indexed keywords


EID: 77958180798     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (4)

References (87)
  • 1
    • 0026341239 scopus 로고
    • Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide
    • Nielsen PE, Egholm M, Berg RH, and Buchardt O: Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science, 254: 1497; 1991.
    • (1991) Science , vol.254 , pp. 1497
    • Nielsen, P.E.1    Egholm, M.2    Berg, R.H.3    Buchardt, O.4
  • 2
    • 1542782928 scopus 로고    scopus 로고
    • Recent advances in the development of peptide nucleic acid as a gene-targeted drug
    • Marin VL, Roy S, and Armitage BA: Recent advances in the development of peptide nucleic acid as a gene-targeted drug. Expert Opinion on Biological Therapy, 4: 337; 2004.
    • (2004) Expert Opinion on Biological Therapy , vol.4 , pp. 337
    • Marin, V.L.1    Roy, S.2    Armitage, B.A.3
  • 5
    • 33745928141 scopus 로고    scopus 로고
    • Biological activity and biotechnological aspects of peptide nucleic acid
    • Lundin KE, Good L, Stromberg R et al.: Biological activity and biotechnological aspects of peptide nucleic acid. Advances in Genetics, 56: 1 2006.
    • (2006) Advances in Genetics , vol.56 , pp. 1
    • Lundin, K.E.1    Good, L.2    Stromberg, R.3
  • 6
    • 0032766821 scopus 로고    scopus 로고
    • Peptide nucleic acid. A molecule with two identities
    • Nielsen PE: Peptide nucleic acid. A molecule with two identities. Accounts of Chemical Research, 32:624; 1999.
    • (1999) Accounts of Chemical Research , vol.32 , pp. 624
    • Nielsen, P.E.1
  • 7
    • 20444448113 scopus 로고    scopus 로고
    • Conformationally constrained PNA analogues: Structural evolution toward DNA/RNA binding selectivity
    • Kumar VA and Ganesh KN: Conformationally constrained PNA analogues: structural evolution toward DNA/RNA binding selectivity. Accounts of Chemical Research, 38: 404 2005.
    • (2005) Accounts of Chemical Research , vol.38 , pp. 404
    • Kumar, V.A.1    Ganesh, K.N.2
  • 8
    • 0032565941 scopus 로고    scopus 로고
    • Peptide nucleic acids (PNAs) with a functional backbone
    • Püschl A, Sforza S, Haaima G et al.: Peptide nucleic acids (PNAs) with a functional backbone. Tetrahedron Letters, 39: 4707 1998.
    • (1998) Tetrahedron Letters , vol.39 , pp. 4707
    • Püschl, A.1    Sforza, S.2    Haaima, G.3
  • 9
    • 0028234790 scopus 로고
    • A convenient synthesis of chiral peptide nucleic acid (PNA) monomers
    • Kosynkina L, Wang W, and Liang TC: A convenient synthesis of chiral peptide nucleic acid (PNA) monomers. Tetrahedron Lett, 35: 5173 1994.
    • (1994) Tetrahedron Lett , vol.35 , pp. 5173
    • Kosynkina, L.1    Wang, W.2    Liang, T.C.3
  • 10
    • 0035830450 scopus 로고    scopus 로고
    • Inhibition of gene expression inside cells by peptide nucleic acids: Effect of mRNA target sequence, mismatched bases, and PNA length
    • Doyle DF, Braasch DA, Simmons CG et al.: Inhibition of gene expression inside cells by peptide nucleic acids: effect of mRNA target sequence, mismatched bases, and PNA length. Biochemistry, 40:53; 2001.
    • (2001) Biochemistry , vol.40 , pp. 53
    • Doyle, D.F.1    Braasch, D.A.2    Simmons, C.G.3
  • 11
    • 1242352936 scopus 로고    scopus 로고
    • Efficient and isoform-selective inhibition of cellular gene expression by peptide nucleic acids
    • Liu Y, Braasch DA, Nulf CJ et al.: Efficient and isoform-selective inhibition of cellular gene expression by peptide nucleic acids. Biochemistry, 43: 1921 2004.
    • (2004) Biochemistry , vol.43 , pp. 1921
    • Liu, Y.1    Braasch, D.A.2    Nulf, C.J.3
  • 12
    • 4544379668 scopus 로고    scopus 로고
    • Down-regulation of MDM2 and activation of p53 in human cancer cells by antisense 9-aminoacridine-PNA (peptide nucleic acid) conjugates
    • Shiraishi T and Nielsen PE: Down-regulation of MDM2 and activation of p53 in human cancer cells by antisense 9-aminoacridine-PNA (peptide nucleic acid) conjugates. Nucleic Acids Research, 32:4893; 2004.
    • (2004) Nucleic Acids Research , vol.32 , pp. 4893
    • Shiraishi, T.1    Nielsen, P.E.2
  • 13
    • 4644365387 scopus 로고    scopus 로고
    • Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA
    • Kilk K, Elmquist A, Saar K, et al.: Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA. Neuropeptides, 38: 316 2004.
    • (2004) Neuropeptides , vol.38 , pp. 316
    • Kilk, K.1    Elmquist, A.2    Saar, K.3
  • 14
    • 0035477551 scopus 로고    scopus 로고
    • Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs
    • Sazani P, Kang SH, Maier MA, et al.: Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs. Nucleic Acids Research, 29: 3965 2001.
    • (2001) Nucleic Acids Research , vol.29 , pp. 3965
    • Sazani, P.1    Kang, S.H.2    Maier, M.A.3
  • 15
    • 0037313165 scopus 로고    scopus 로고
    • Correction of disease-associated exon skipping by synthetic exon-specific activators
    • Cartegni L and Krainer AR: Correction of disease-associated exon skipping by synthetic exon-specific activators. Nature Structural Biology, 10: 120 2003.
    • (2003) Nature Structural Biology , vol.10 , pp. 120
    • Cartegni, L.1    Krainer, A.R.2
  • 16
    • 2542610648 scopus 로고    scopus 로고
    • Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing
    • Siwkowski AM, Malik L, Esau CC, et al.: Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing. Nucleic Acids Research, 32: 2695 2004.
    • (2004) Nucleic Acids Research , vol.32 , pp. 2695
    • Siwkowski, A.M.1    Malik, L.2    Esau, C.C.3
  • 17
    • 29144514696 scopus 로고    scopus 로고
    • Chimeric peptide nucleic acid compounds modulate splicing of the bcl-x gene in vitro and in vivo
    • Wilusz JE, Devanney SC, and Caputi M: Chimeric peptide nucleic acid compounds modulate splicing of the bcl-x gene in vitro and in vivo. Nucleic Acids Research, 33: 6547 2005.
    • (2005) Nucleic Acids Research , vol.33 , pp. 6547
    • Wilusz, J.E.1    Devanney, S.C.2    Caputi, M.3
  • 18
    • 0033455559 scopus 로고    scopus 로고
    • Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
    • Herbert BS, Pitts AE, Baker SI et al.: Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death. Proceedings of the National Academy of Science USA, 96: 14,276; 1999.
    • (1999) Proceedings of the National Academy of Science USA , vol.96 , Issue.14 , pp. 276
    • Herbert, B.S.1    Pitts, A.E.2    Baker, S.I.3
  • 19
    • 0038159280 scopus 로고    scopus 로고
    • Photochemical internalization of a peptide nucleic acid targeting the catalytic subunit of human telomerase
    • Folini M, Berg K, Millo E et al.: Photochemical internalization of a peptide nucleic acid targeting the catalytic subunit of human telomerase. Cancer Research, 63: 3490 2003.
    • (2003) Cancer Research , vol.63 , pp. 3490
    • Folini, M.1    Berg, K.2    Millo, E.3
  • 20
    • 0028500559 scopus 로고
    • Evidence for (PNA)2/DNA triplex structure upon binding of PNA to dsDNA by strand displacement
    • Nielsen PE, Egholm M, and Buchardt O: Evidence for (PNA)2/DNA triplex structure upon binding of PNA to dsDNA by strand displacement. Journal of Molecular Recognition, 7: 165 1994.
    • (1994) Journal of Molecular Recognition , vol.7 , pp. 165
    • Nielsen, P.E.1    Egholm, M.2    Buchardt, O.3
  • 21
    • 33845679853 scopus 로고    scopus 로고
    • Structural diversity of target specific homopyrimidine peptide nucleic acid-dsDNA complexes
    • Bentin T, Hansen GI, and Nielsen PE: Structural diversity of target specific homopyrimidine peptide nucleic acid-dsDNA complexes. Nucleic Acids Research, 34: 5790 2006.
    • (2006) Nucleic Acids Research , vol.34 , pp. 5790
    • Bentin, T.1    Hansen, G.I.2    Nielsen, P.E.3
  • 22
    • 0037837659 scopus 로고    scopus 로고
    • Superior duplex DNA strand invasion by acridine conjugated peptide nucleic acids
    • Bentin T and Nielsen PE: Superior duplex DNA strand invasion by acridine conjugated peptide nucleic acids. Journal of the American Chemical Society, 125: 6378 2003.
    • (2003) Journal of the American Chemical Society , vol.125 , pp. 6378
    • Bentin, T.1    Nielsen, P.E.2
  • 23
    • 0028928953 scopus 로고
    • Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA
    • Egholm M, Christensen L, Dueholm KL et al.: Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA. Nucleic Acids Research, 23: 217 1995.
    • (1995) Nucleic Acids Research , vol.23 , pp. 217
    • Egholm, M.1    Christensen, L.2    Dueholm, K.L.3
  • 24
    • 0029963160 scopus 로고    scopus 로고
    • Strand displacement binding of a duplex-forming homopurine PNA to a homopyrimidine duplex DNA target
    • Nielsen PE and Christensen L: Strand displacement binding of a duplex-forming homopurine PNA to a homopyrimidine duplex DNA target. Journal of the American Chemical Society, 118: 2287 1996.
    • (1996) Journal of the American Chemical Society , vol.118 , pp. 2287
    • Nielsen, P.E.1    Christensen, L.2
  • 25
    • 0034283848 scopus 로고    scopus 로고
    • Strand invasion by mixed base PNAs and a PNA-peptide chimera
    • Zhang X, Ishihara T, and Corey DR: Strand invasion by mixed base PNAs and a PNA-peptide chimera. Nucleic Acids Research, 28: 3332 2000.
    • (2000) Nucleic Acids Research , vol.28 , pp. 3332
    • Zhang, X.1    Ishihara, T.2    Corey, D.R.3
  • 26
    • 0032738421 scopus 로고    scopus 로고
    • Double duplex invasion by peptide nucleic acid: A general principle for sequence-specific targeting of double-stranded DNA
    • Lohse J, Dahl O, and Nielsen PE: Double duplex invasion by peptide nucleic acid: a general principle for sequence-specific targeting of double-stranded DNA. Proceedings of the National Academy of Science USA, 96: 11,804; 1999.
    • (1999) Proceedings of the National Academy of Science USA , vol.96 , Issue.11 , pp. 804
    • Lohse, J.1    Dahl, O.2    Nielsen, P.E.3
  • 28
    • 0028075767 scopus 로고
    • Sequence-specific transcription arrest by peptide nucleic acid bound to the DNA template strand
    • Nielsen PE, Egholm M, and Buchardt O: Sequence-specific transcription arrest by peptide nucleic acid bound to the DNA template strand. Gene, 149: 139 1994.
    • (1994) Gene , vol.149 , pp. 139
    • Nielsen, P.E.1    Egholm, M.2    Buchardt, O.3
  • 29
    • 33644832338 scopus 로고    scopus 로고
    • Inhibiting transcription of chromosomal DNA with antigene peptide nucleic acids
    • Janowski BA, Kaihatsu K, Huffman KE et al.: Inhibiting transcription of chromosomal DNA with antigene peptide nucleic acids. Nature Chemical Biology, 1: 210 2005.
    • (2005) Nature Chemical Biology , vol.1 , pp. 210
    • Janowski, B.A.1    Kaihatsu, K.2    Huffman, K.E.3
  • 31
    • 0034724416 scopus 로고    scopus 로고
    • An approach to gene-specific transcription inhibition using oligonucleotides complementary to the template strand of the open complex
    • Milne L, Xu Y, Perrin DM, and Sigman DS: An approach to gene-specific transcription inhibition using oligonucleotides complementary to the template strand of the open complex. Proceedings of the National Academy of Science USA, 97: 3136 2000.
    • (2000) Proceedings of the National Academy of Science USA , vol.97 , pp. 3136
    • Milne, L.1    Xu, Y.2    Perrin, D.M.3    Sigman, D.S.4
  • 33
    • 0033168095 scopus 로고    scopus 로고
    • Peptide nucleic acid (PNA) binding-mediated induction of human γ-globin gene expression
    • Wang G, Xu X, Pace B, Dean DA et al.: Peptide nucleic acid (PNA) binding-mediated induction of human γ-globin gene expression. Nucleic Acids Research, 27: 2806 1999.
    • (1999) Nucleic Acids Research , vol.27 , pp. 2806
    • Wang, G.1    Xu, X.2    Pace, B.3    Dean, D.A.4
  • 34
    • 30144444691 scopus 로고    scopus 로고
    • Site-specific gene modification by PNAs conjugated to psoralen
    • Kim KH, Nielsen PE, and Glazer PM: Site-specific gene modification by PNAs conjugated to psoralen. Biochemistry, 45: 314 2006.
    • (2006) Biochemistry , vol.45 , pp. 314
    • Kim, K.H.1    Nielsen, P.E.2    Glazer, P.M.3
  • 35
    • 31544461288 scopus 로고    scopus 로고
    • PNA-nitrogen mustard conjugates are effective suppressors of HER-2/neu and biological tools for recognition of PNA/DNA Interactions
    • Zhilina ZV, Ziemba AJ, Nielsen PE, and Ebbinghaus SW: PNA-nitrogen mustard conjugates are effective suppressors of HER-2/neu and biological tools for recognition of PNA/DNA Interactions. Bioconjugate Chemistry, 17: 214 2006.
    • (2006) Bioconjugate Chemistry , vol.17 , pp. 214
    • Zhilina, Z.V.1    Ziemba, A.J.2    Nielsen, P.E.3    Ebbinghaus, S.W.4
  • 36
    • 15744399605 scopus 로고    scopus 로고
    • Targeting and regulation of the HER-2/neu oncogene promoter with bis-peptide nucleic acids
    • Ziemba AJ, Zhilina ZV, Krotova-Khan Y et al.: Targeting and regulation of the HER-2/neu oncogene promoter with bis-peptide nucleic acids. Oligonucleotides, 15: 36 2005.
    • (2005) Oligonucleotides , vol.15 , pp. 36
    • Ziemba, A.J.1    Zhilina, Z.V.2    Krotova-Khan, Y.3
  • 37
    • 18944373328 scopus 로고    scopus 로고
    • Highly efficient endogenous human gene correction using designed zinc-finger nucleases
    • Urnov FD, Miller JC, Lee YL et al. Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature, 435: 646 2005.
    • (2005) Nature , vol.435 , pp. 646
    • Urnov, F.D.1    Miller, J.C.2    Lee, Y.L.3
  • 38
    • 0034061532 scopus 로고    scopus 로고
    • Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal
    • Cutrona G, Carpaneto EM, Ulivi M et al.: Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal. Nature Biotechnology, 18: 300 2000.
    • (2000) Nature Biotechnology , vol.18 , pp. 300
    • Cutrona, G.1    Carpaneto, E.M.2    Ulivi, M.3
  • 39
    • 4043074259 scopus 로고    scopus 로고
    • Targeted inhibition of NMYC by peptide nucleic acid in N-myc amplified human neuroblastoma cells: Cell-cycle inhibition with induction of neuronal cell differentiation and apoptosis
    • Pession A, Tonelli R, Fronza R et al.: Targeted inhibition of NMYC by peptide nucleic acid in N-myc amplified human neuroblastoma cells: cell-cycle inhibition with induction of neuronal cell differentiation and apoptosis. International Journal of Oncology, 24: 265 2004.
    • (2004) International Journal of Oncology , vol.24 , pp. 265
    • Pession, A.1    Tonelli, R.2    Fronza, R.3
  • 40
    • 23244452962 scopus 로고    scopus 로고
    • Transcription inhibition of oncogenic KRAS by a mutationselective peptide nucleic acid conjugated to the PKKKRKV nuclear localization signal peptide
    • Cogoi S, Codognotto A, Rapozzi V et al.: Transcription inhibition of oncogenic KRAS by a mutationselective peptide nucleic acid conjugated to the PKKKRKV nuclear localization signal peptide. Biochemistry, 44: 10,510; 2005.
    • (2005) Biochemistry , vol.44 , Issue.10 , pp. 510
    • Cogoi, S.1    Codognotto, A.2    Rapozzi, V.3
  • 41
    • 20044370996 scopus 로고    scopus 로고
    • Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis
    • Tonelli R, Purgato S, Camerin C et al.: Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis. Molecular Cancer Therapy, 4: 779 2005.
    • (2005) Molecular Cancer Therapy , vol.4 , pp. 779
    • Tonelli, R.1    Purgato, S.2    Camerin, C.3
  • 42
    • 33646950391 scopus 로고    scopus 로고
    • Evaluation of cell-penetrating peptides (CPPs) as vehicles for intracellular delivery of Antisense peptide nucleic acid (PNA)
    • Bendifallah N, Rasmussen FW, Zachar V et al.: Evaluation of cell-penetrating peptides (CPPs) as vehicles for intracellular delivery of Antisense peptide nucleic acid (PNA). Bioconjugate Chemistry, 17: 750 2006.
    • (2006) Bioconjugate Chemistry , vol.17 , pp. 750
    • Bendifallah, N.1    Rasmussen, F.W.2    Zachar, V.3
  • 43
    • 0032478330 scopus 로고    scopus 로고
    • Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA
    • Good L and Nielsen PE: Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA. Proceedings of the National Academy of Science USA, 95: 2073 1998.
    • (1998) Proceedings of the National Academy of Science USA , vol.95 , pp. 2073
    • Good, L.1    Nielsen, P.E.2
  • 44
    • 0035075441 scopus 로고    scopus 로고
    • Bactericidal antisense effects of peptide-PNA conjugates
    • Good L, Awasthi SK, Dryselius R et al.: Bactericidal antisense effects of peptide-PNA conjugates. Nature Biotechnology, 19: 360 2001.
    • (2001) Nature Biotechnology , vol.19 , pp. 360
    • Good, L.1    Awasthi, S.K.2    Dryselius, R.3
  • 45
    • 23044484982 scopus 로고    scopus 로고
    • Peptide nucleic acid antisense oligomer as a therapeutic strategy against bacterial infection: Proof of principle using mouse intraperitoneal infection
    • Tan XX, Actor JK, and Chen Y: Peptide nucleic acid antisense oligomer as a therapeutic strategy against bacterial infection: proof of principle using mouse intraperitoneal infection. Antimicrobial Agents and Chemotherapy, 49: 3203 2005.
    • (2005) Antimicrobial Agents and Chemotherapy , vol.49 , pp. 3203
    • Tan, X.X.1    Actor, J.K.2    Chen, Y.3
  • 48
    • 1542333740 scopus 로고    scopus 로고
    • The translation start codon region is sensitive to antisense PNA inhibition in Escherichia coli
    • Dryselius R, Aswasti SK, Rajarao GK et al.: The translation start codon region is sensitive to antisense PNA inhibition in Escherichia coli. Oligonucleotides, 13: 427 2003.
    • (2003) Oligonucleotides , vol.13 , pp. 427
    • Dryselius, R.1    Aswasti, S.K.2    Rajarao, G.K.3
  • 51
    • 4644226298 scopus 로고    scopus 로고
    • Inhibition of Staphylococcus aureus gene expression and growth using antisense peptide nucleic acids
    • Nekhotiaeva N, Awasthi SK, Nielsen PE, and Good L: Inhibition of Staphylococcus aureus gene expression and growth using antisense peptide nucleic acids. Molecular Therapy, 10: 652 2004.
    • (2004) Molecular Therapy , vol.10 , pp. 652
    • Nekhotiaeva, N.1    Awasthi, S.K.2    Nielsen, P.E.3    Good, L.4
  • 52
    • 0035104169 scopus 로고    scopus 로고
    • Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers
    • Stock RP, Olvera A, Sánchez R et al.: Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers. Nature Biotechnology, 19: 231 2001.
    • (2001) Nature Biotechnology , vol.19 , pp. 231
    • Stock, R.P.1    Olvera, A.2    Sánchez, R.3
  • 53
    • 14744283591 scopus 로고    scopus 로고
    • Entamoeba histolytica: Intracellular distribution of the sec61alpha subunit of the secretory pathway and down-regulation by antisense peptide nucleic acids
    • Sánchez R, Saralegui A, Olivos-Garcia A et al.: Entamoeba histolytica: intracellular distribution of the sec61alpha subunit of the secretory pathway and down-regulation by antisense peptide nucleic acids. Experimental Parasitology, 109: 241 2005.
    • (2005) Experimental Parasitology , vol.109 , pp. 241
    • Sánchez, R.1    Saralegui, A.2    Olivos-Garcia, A.3
  • 54
    • 0030842070 scopus 로고    scopus 로고
    • Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA
    • Koppelhus U, Zachar V, Nielsen PE et al.: Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA. Nucleic Acids Research, 25: 2167 1997.
    • (1997) Nucleic Acids Research , vol.25 , pp. 2167
    • Koppelhus, U.1    Zachar, V.2    Nielsen, P.E.3
  • 55
    • 0036775938 scopus 로고    scopus 로고
    • Inhibition of HIV-1 replication by anti-trans-activation responsive polyamide nucleotide analog
    • Kaushik N, Basu A, and Pandey VN: Inhibition of HIV-1 replication by anti-trans-activation responsive polyamide nucleotide analog. Antiviral Research, 56: 13 2002.
    • (2002) Antiviral Research , vol.56 , pp. 13
    • Kaushik, N.1    Basu, A.2    Pandey, V.N.3
  • 56
    • 4544328474 scopus 로고    scopus 로고
    • A peptide nucleic acid-neamine conjugate that targets and cleaves HIV-1 TAR RNA inhibits viral replication
    • Riguet E, Tripathi S, Chaubey B et al.: A peptide nucleic acid-neamine conjugate that targets and cleaves HIV-1 TAR RNA inhibits viral replication. Journal of Medicinal Chemistry, 47: 4806 2004.
    • (2004) Journal of Medicinal Chemistry , vol.47 , pp. 4806
    • Riguet, E.1    Tripathi, S.2    Chaubey, B.3
  • 57
    • 11344260182 scopus 로고    scopus 로고
    • A PNA-transportan conjugate targeted to the TAR region of the HIV-1 genome exhibits both antiviral and virucidal properties
    • Chaubey B, Tripathi S, Ganguly S et al.: A PNA-transportan conjugate targeted to the TAR region of the HIV-1 genome exhibits both antiviral and virucidal properties. Virology, 331: 418 2005.
    • (2005) Virology , vol.331 , pp. 418
    • Chaubey, B.1    Tripathi, S.2    Ganguly, S.3
  • 58
    • 20144365614 scopus 로고    scopus 로고
    • Anti-gene peptide nucleic acid targeted to proviral HIV-1 DNA inhibits in vitro HIV-1 replication
    • Pesce CD, Bolacchi F, Bongiovanni B et al.: Anti-gene peptide nucleic acid targeted to proviral HIV-1 DNA inhibits in vitro HIV-1 replication. Antiviral Research, 66: 13 2005.
    • (2005) Antiviral Research , vol.66 , pp. 13
    • Pesce, C.D.1    Bolacchi, F.2    Bongiovanni, B.3
  • 59
    • 23844510658 scopus 로고    scopus 로고
    • Anti-HIV-1 activity of anti-TAR polyamide nucleic acid conjugated with various membrane transducing peptides
    • Tripathi S, Chaubey B, Ganguly S et al.: Anti-HIV-1 activity of anti-TAR polyamide nucleic acid conjugated with various membrane transducing peptides. Nucleic Acids Research, 33: 4345 2005.
    • (2005) Nucleic Acids Research , vol.33 , pp. 4345
    • Tripathi, S.1    Chaubey, B.2    Ganguly, S.3
  • 60
    • 29344436510 scopus 로고    scopus 로고
    • Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells
    • Turner JJ, Ivanova GD, Verbeure B et al.: Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells. Nucleic Acids Research, 33:6837; 2005.
    • (2005) Nucleic Acids Research , vol.33 , pp. 6837
    • Turner, J.J.1    Ivanova, G.D.2    Verbeure, B.3
  • 61
    • 3142762898 scopus 로고    scopus 로고
    • Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs)
    • Nulf CJ and Corey D: Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs). Nucleic Acids Research, 32: 3792 2004.
    • (2004) Nucleic Acids Research , vol.32 , pp. 3792
    • Nulf, C.J.1    Corey, D.2
  • 62
    • 19944433419 scopus 로고    scopus 로고
    • Sequence-specific inhibition of duck hepatitis B virus reverse transcription by peptide nucleic acids (PNA)
    • Robaczewska M, Narayan R, Seigneres B et al.: Sequence-specific inhibition of duck hepatitis B virus reverse transcription by peptide nucleic acids (PNA). Journal of Hepatology, 42: 180 2005.
    • (2005) Journal of Hepatology , vol.42 , pp. 180
    • Robaczewska, M.1    Narayan, R.2    Seigneres, B.3
  • 65
    • 31544451318 scopus 로고    scopus 로고
    • Cellular delivery of polyheteroaromate-peptide nucleic acid (PNA) conjugates mediated by cationic lipids
    • Shiraishi T, Nadia Bendifallah N, and Nielsen PE: Cellular delivery of polyheteroaromate-peptide nucleic acid (PNA) conjugates mediated by cationic lipids. Bioconjugate Chemistry, 17: 189 2006.
    • (2006) Bioconjugate Chemistry , vol.17 , pp. 189
    • Shiraishi, T.1    Nadia Bendifallah, N.2    Nielsen, P.E.3
  • 66
    • 27744528180 scopus 로고    scopus 로고
    • Endocytosis and cationic cell-penetrating peptides-a merger of concepts and methods
    • Fotin-Mleczek M, Fischer R, and Brock R: Endocytosis and cationic cell-penetrating peptides-a merger of concepts and methods. Current Pharmaceutical Design, 11: 3613 2005.
    • (2005) Current Pharmaceutical Design , vol.11 , pp. 3613
    • Fotin-Mleczek, M.1    Fischer, R.2    Brock, R.3
  • 67
  • 68
    • 0346460957 scopus 로고    scopus 로고
    • Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake
    • Richard JP, Melikov K, Vives E et al. Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. Journal of Biological Chemistry, 278: 585 2003.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 585
    • Richard, J.P.1    Melikov, K.2    Vives, E.3
  • 69
    • 31544458695 scopus 로고    scopus 로고
    • Endosome trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates
    • Abes S, Williams D, Prevot P et al.: Endosome trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates. Journal of Controlled Release, 110: 595 2006.
    • (2006) Journal of Controlled Release , vol.110 , pp. 595
    • Abes, S.1    Williams, D.2    Prevot, P.3
  • 70
    • 2342595835 scopus 로고    scopus 로고
    • Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
    • Wadia JS, Stan RV, and Dowdy SF: Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nature Medicine, 10: 310 2004.
    • (2004) Nature Medicine , vol.10 , pp. 310
    • Wadia, J.S.1    Stan, R.V.2    Dowdy, S.F.3
  • 71
    • 23944455368 scopus 로고    scopus 로고
    • Calcium ions effectively enhance the effect of antisense peptide nucleic acids conjugated to cationic tat and oligoarginine peptides
    • Shiraishi T, Pankratova S, and Nielsen PE: Calcium ions effectively enhance the effect of antisense peptide nucleic acids conjugated to cationic tat and oligoarginine peptides. Chemistry & Biology, 12:923; 2005.
    • (2005) Chemistry & Biology , vol.12 , pp. 923
    • Shiraishi, T.1    Pankratova, S.2    Nielsen, P.E.3
  • 72
    • 32344441681 scopus 로고    scopus 로고
    • Photochemically enhanced cellular delivery of cell penetrating peptide-PNA conjugates
    • Shiraishi T and Nielsen PE: Photochemically enhanced cellular delivery of cell penetrating peptide-PNA conjugates. FEBS Letters, 580: 1451 2006.
    • (2006) FEBS Letters , vol.580 , pp. 1451
    • Shiraishi, T.1    Nielsen, P.E.2
  • 73
    • 33745187593 scopus 로고    scopus 로고
    • Photochemically induced gene silencing using PNA-peptide conjugates
    • Bøe S, Hovig E: Photochemically induced gene silencing using PNA-peptide conjugates. Oligonucleotides, 16: 145 2006.
    • (2006) Oligonucleotides , vol.16 , pp. 145
    • Bøe, S.1    Hovig, E.2
  • 74
    • 27144435910 scopus 로고    scopus 로고
    • Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid
    • Albertshofer K, Siwkowski AM, Wancewicz EV et al.: Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid. Journal of Medicinal Chemistry, 48: 6741 2005.
    • (2005) Journal of Medicinal Chemistry , vol.48 , pp. 6741
    • Albertshofer, K.1    Siwkowski, A.M.2    Wancewicz, E.V.3
  • 75
    • 33646076467 scopus 로고    scopus 로고
    • Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids
    • Maier MA, Esau CC, Siwkowski AM et al.: Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids. Journal of Medicinal Chemistry, 49: 2534 2006.
    • (2006) Journal of Medicinal Chemistry , vol.49 , pp. 2534
    • Maier, M.A.1    Esau, C.C.2    Siwkowski, A.M.3
  • 76
    • 22644440063 scopus 로고    scopus 로고
    • Arginine-rich peptide conjugation to morpholino oligomers: Effects on antisense activity and specificity
    • Nelson MH, Stein DA, Kroeker AD et al.: Arginine-rich peptide conjugation to morpholino oligomers:effects on antisense activity and specificity. Bioconjugate Chemistry, 16: 959 2005.
    • (2005) Bioconjugate Chemistry , vol.16 , pp. 959
    • Nelson, M.H.1    Stein, D.A.2    Kroeker, A.D.3
  • 78
    • 0346725016 scopus 로고    scopus 로고
    • Delivery of antisense peptide nucleic acids (PNAs) to the cytosol by disulphide conjugation to a lipophilic cation
    • Filipovska A, Eccles MR, Smith RAJ, and Murphy MP: Delivery of antisense peptide nucleic acids (PNAs) to the cytosol by disulphide conjugation to a lipophilic cation. FEBS Letters, 556: 180 2004.
    • (2004) FEBS Letters , vol.556 , pp. 180
    • Filipovska, A.1    Eccles, M.R.2    Smith, R.A.J.3    Murphy, M.P.4
  • 80
    • 12744261270 scopus 로고    scopus 로고
    • Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA
    • Dragulescu-Andrasi A, Zhou P, He G, and Ly DH: Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA. Chemical Communications, 244; 2005.
    • (2005) Chemical Communications , pp. 244
    • Dragulescu-Andrasi, A.1    Zhou, P.2    He, G.3    Ly, D.H.4
  • 81
    • 0141681146 scopus 로고    scopus 로고
    • Modulation of the pharmacokinetic properties of PNA:Preparation of galactosyl, mannosyl, fucosyl, N-acetylgalactosaminyl, and N-acetylglucosaminyl derivatives of aminoethylglycine peptide nucleic acid monomers and their incorporation into PNA oligomers
    • Hamzavi R, Dolle F, Tavitian B et al.: Modulation of the pharmacokinetic properties of PNA:Preparation of galactosyl, mannosyl, fucosyl, N-acetylgalactosaminyl, and N-acetylglucosaminyl derivatives of aminoethylglycine peptide nucleic acid monomers and their incorporation into PNA oligomers. Bioconjugate Chemistry, 14: 941 2003.
    • (2003) Bioconjugate Chemistry , vol.14 , pp. 941
    • Hamzavi, R.1    Dolle, F.2    Tavitian, B.3
  • 82
    • 0035933505 scopus 로고    scopus 로고
    • Intraperitoneal injection of antisense peptide nucleic acids targeted to the mu receptor decreases response to morphine and receptor protein levels in rat brain
    • McMahon BM, Stewart JA, Jackson J et al.: Intraperitoneal injection of antisense peptide nucleic acids targeted to the mu receptor decreases response to morphine and receptor protein levels in rat brain. Brain Research, 904: 345 2001.
    • (2001) Brain Research , vol.904 , pp. 345
    • McMahon, B.M.1    Stewart, J.A.2    Jackson, J.3
  • 83
    • 0037036164 scopus 로고    scopus 로고
    • Peptide nucleic acids specifically cause antigene effects in vivo by systemic injection
    • McMahon BM, Stewart JA, Bitner MD et al.: Peptide nucleic acids specifically cause antigene effects in vivo by systemic injection. Life Sciences, 71: 325 2002.
    • (2002) Life Sciences , vol.71 , pp. 325
    • McMahon, B.M.1    Stewart, J.A.2    Bitner, M.D.3
  • 84
    • 16544393156 scopus 로고    scopus 로고
    • Down-regulation of amyloid precursor protein by peptide nucleic acid in vivo
    • Boules M, Williams K, Gollatz E et al.: Down-regulation of amyloid precursor protein by peptide nucleic acid in vivo. Journal of Molecular Neuroscience, 24: 123 2004.
    • (2004) Journal of Molecular Neuroscience , vol.24 , pp. 123
    • Boules, M.1    Williams, K.2    Gollatz, E.3
  • 85
    • 0036363313 scopus 로고    scopus 로고
    • In vitro and in vivo studies on pharmacokinetics and metabolism of PNA constructs in rodents
    • PE Nielsen ed. Copenhagen: Humana Press (Totowa, NJ, United States)
    • Kristensen E: In vitro and in vivo studies on pharmacokinetics and metabolism of PNA constructs in rodents. In Peptide Nucleic Acids: Methods and Protocols, PE Nielsen ed. Copenhagen: Humana Press (Totowa, NJ, United States); 2002, pp. 259-269.
    • (2002) Peptide Nucleic Acids: Methods and Protocols , pp. 259-269
    • Kristensen, E.1
  • 86
    • 0035989848 scopus 로고    scopus 로고
    • Pharmacokinetics and tissue distribution of a peptide nucleic acid after intravenous administration
    • McMahon BM, Mays D, Lipsky J et al.: Pharmacokinetics and tissue distribution of a peptide nucleic acid after intravenous administration. Antisense and Nucleic Acid Drug Development, 12: 65 2002.
    • (2002) Antisense and Nucleic Acid Drug Development , vol.12 , pp. 65
    • McMahon, B.M.1    Mays, D.2    Lipsky, J.3
  • 87
    • 0036903132 scopus 로고    scopus 로고
    • Systemically delivered antisense oligomers upregulate gene expression in mouse tissues
    • Sazani P, Gemignani F, Kang S-H et al.: Systemically delivered antisense oligomers upregulate gene expression in mouse tissues. Nature Biotechnology, 20: 1228 2002.
    • (2002) Nature Biotechnology , vol.20 , pp. 1228
    • Sazani, P.1    Gemignani, F.2    Kang, S.-H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.