PNA-nitrogen mustard conjugates are effective suppressors of HER-2/neu and biological tools for recognition of PNA/DNA interactions

Bioconjugate Chemistry

Volumn 17, Issue 1, 2006, Pages 214-222

  Zhilina, Zhanna V ^a   Ziemba, Amy J ^a   Nielsen, Peter E ^b   Ebbinghaus, Scot W ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; BINDING ENERGY; BINDING SITES; DNA SEQUENCES; EFFICIENCY; NITROGEN; OLIGONUCLEOTIDES; TRANSCRIPTION;

ALKYLATING AGENTS; CRITICAL SEQUENCE; DNA ALKYLATIONS; DNA INTERACTION; DNA TRIPLEXES; GEL SHIFT ANALYSIS; GENE REGULATORS; GENE-REGULATION; NITROGEN MUSTARDS; PEPTIDE NUCLEIC ACID;

DNA;

ALKYLATING AGENT; ANTISENSE OLIGONUCLEOTIDE; CHLORAMBUCIL; CHLORMETHINE; CHLORPHENACYL; DNA; PEPTIDE NUCLEIC ACID; PHENYLACETIC ACID DERIVATIVE; PIPERIDINE; PYRIMIDINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BASE PAIRING; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA ALKYLATION; DRUG CONJUGATION; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; ONCOGENE NEU; PROMOTER REGION; TRANSCRIPTION REGULATION;

BRASSICACEAE;

EID: 31544461288     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0502964     Document Type: Article

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