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Volumn 32, Issue 7, 1999, Pages 624-630

Peptide nucleic acid. A molecule with two identities

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DOUBLE STRANDED DNA; NUCLEIC ACID BASE; PEPTIDE NUCLEIC ACID; PROTEIN; RNA;

EID: 0032766821     PISSN: 00014842     EISSN: None     Source Type: Journal    
DOI: 10.1021/ar980010t     Document Type: Article
Times cited : (382)

References (77)
  • 1
    • 0029986009 scopus 로고    scopus 로고
    • Peptide nucleic acids (PNA). Synthesis, properties and potential applications (review)
    • Hyrup, B.; Nielsen, P. E. Peptide Nucleic Acids (PNA). Synthesis, Properties and Potential Applications (review). Bioorg. Biomed. Chem. 1996, 4, 5-23.
    • (1996) Bioorg. Biomed. Chem. , vol.4 , pp. 5-23
    • Hyrup, B.1    Nielsen, P.E.2
  • 2
    • 27844435286 scopus 로고    scopus 로고
    • Chemical aspects of peptide nucleic acid (review)
    • Dueholm, K.; Nielsen, P. E. Chemical aspects of peptide nucleic acid (review). New J. Chem. 1996, 21, 19-31.
    • (1996) New J. Chem. , vol.21 , pp. 19-31
    • Dueholm, K.1    Nielsen, P.E.2
  • 3
    • 0030440962 scopus 로고    scopus 로고
    • PNA-nucleic acid complexes. Structure, stability and dynamics
    • Eriksson, M.; Nielsen, P. E. PNA-nucleic acid complexes. Structure, stability and dynamics. Q. Rev. Biophys. 1996, 29, 369-394.
    • (1996) Q. Rev. Biophys. , vol.29 , pp. 369-394
    • Eriksson, M.1    Nielsen, P.E.2
  • 4
    • 0032476790 scopus 로고    scopus 로고
    • PNA: Synthetic polyamide nucleic acids with unusual binding properties
    • Uhlmann, E.; Peyman, A.; Breipohl, G.; Will, D. W. PNA: Synthetic Polyamide Nucleic Acids with unusual binding properties. Angew. Chem., Int. Ed. Engl. 1998, 37, 2796-2823.
    • (1998) Angew. Chem., Int. Ed. Engl. , vol.37 , pp. 2796-2823
    • Uhlmann, E.1    Peyman, A.B.G.2    Will, D.W.3
  • 5
    • 0026341239 scopus 로고
    • Sequence selective recognition of DNA by strand displacement with a thymine-substituted polyamide
    • Nielsen, P. E.; Egholm, M.; Berg, R. H.; Buchardt, O. Sequence selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science 1991, 254, 1497-1500.
    • (1991) Science , vol.254 , pp. 1497-1500
    • Nielsen, P.E.1    Egholm, M.2    Berg, R.H.3    Buchardt, O.4
  • 6
    • 84990238662 scopus 로고
    • Peptide nucleic acids (PNA). Oligonucleotide analogues with an achiral peptide backbone
    • Egholm, M.; Buchardt, O.; Nielsen, P. E.; Berg, R. H. Peptide nucleic acids (PNA). Oligonucleotide analogues with an achiral peptide backbone. J. Am. Chem. Soc. 1992, 114, 1895-1897.
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 1895-1897
    • Egholm, M.1    Buchardt, O.2    Nielsen, P.E.3    Berg, R.H.4
  • 7
    • 84990238662 scopus 로고
    • Recognition of guanine and adenine in DNA by cytosine and thymine containing peptide nucleic acids (PNA)
    • Egholm, M.; Buchardt, O.; Nielsen, P. E.; Berg, R. H. Recognition of guanine and adenine in DNA by cytosine and thymine containing peptide nucleic acids (PNA). J. Am. Chem. Soc. 1992, 114, 9677-9678.
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 9677-9678
    • Egholm, M.1    Buchardt, O.2    Nielsen, P.E.3    Berg, R.H.4
  • 8
    • 84977337841 scopus 로고
    • Unconventional nucleotid analogues VI. Synthesis of purinyl-and pyrimidinyl-peptides
    • De Koning, H.; Pandit, U.K. Unconventional Nucleotid Analogues VI. Synthesis of Purinyl-and Pyrimidinyl-Peptides. Recl. Trav. Chim. Pays-Bos 1971, 90, 1069-1080.
    • (1971) Recl. Trav. Chim. Pays-bos , vol.90 , pp. 1069-1080
    • De Koning, H.1    Pandit, U.K.2
  • 9
    • 0002420070 scopus 로고
    • Synthetic analogues of polynucleotides - XIII. The resolution of DL-b-(thymine-lyl)alanine and polymerization of the b-(thymin-1-yl)alanines
    • Buttrey, J. D.; Jones, A. S.; Walker, R. T. Synthetic analogues of Polynucleotides - XIII. The resolution of DL-b-(Thymine-lyl)alanine and polymerization of the b-(Thymin-1-yl)alanines. Tetrahedron 1975, 31, 73-75.
    • (1975) Tetrahedron , vol.31 , pp. 73-75
    • Buttrey, J.D.1    Jones, A.S.2    Walker, R.T.3
  • 10
    • 11944267365 scopus 로고
    • Antisense oligonucleotides: A new therapeutic principle
    • Uhlmann, E.; Peyman, A. Antisense Oligonucleotides: A New Therapeutic Principle. Chem. Rev. 1990, 90, 563-584.
    • (1990) Chem. Rev. , vol.90 , pp. 563-584
    • Uhlmann, E.1    Peyman, A.2
  • 13
    • 0024382446 scopus 로고
    • Uncharged stereoregular nucleic acid analogues: 2. Morpholino nucleoside oligomers with carbamate internucleoside linkages
    • Stirchak, E. P.; Summerton, J. E.; Weller, D. D. Uncharged stereoregular nucleic acid analogues: 2. Morpholino nucleoside oligomers with carbamate internucleoside linkages. Nucleic Acids Res. 1989, 17, 6129-41.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6129-6141
    • Stirchak, E.P.1    Summerton, J.E.2    Weller, D.D.3
  • 14
    • 0030862707 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: Design, preparation, and properties
    • Summerton, J.; Weller, D. Morpholino antisense oligomers: design, preparation, and properties. Antisense Nucleic Acid Drug Dev. 1997, 7, 187-95.
    • (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 187-195
    • Summerton, J.1    Weller, D.2
  • 15
    • 0029937476 scopus 로고    scopus 로고
    • A flexible and positively charged PNA analogue with an ethylene-linker to the nucleobase: Synthesis and hybridization properties
    • Hyrup, B.; Egholm, M.; Buchardt, O.; Nielsen, P. E. A flexible and positively charged PNA analogue with an ethylene-linker to the nucleobase: Synthesis and hybridization properties. Bioorg. Med. Chem. Lett. 1996, 6, 1083-1088.
    • (1996) Bioorg. Med. Chem. Lett. , vol.6 , pp. 1083-1088
    • Hyrup, B.1    Egholm, M.2    Buchardt, O.3    Nielsen, P.E.4
  • 18
    • 85069023160 scopus 로고    scopus 로고
    • LNA (locked nucleic acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition
    • Koshkin, A. A:, Singh, S. K.; Nielsen, P.; Rajwanshi, V. K.; Kumar, R.; Meldgaard, M:, Olsen, C. E.; Wengel, J. LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition. Tetrahedron 1997, 54, 360730.
    • (1997) Tetrahedron , vol.54 , pp. 360730
    • Koshkin, A.A.1    Singh, S.K.2    Nielsen, P.3    Rajwanshi, V.K.4    Kumar, R.5    Meldgaard, M.6    Olsen, C.E.7    Wengel, J.8
  • 19
    • 0028066788 scopus 로고
    • NMR solution structure of a peptide nucleic acid complexed with RNA
    • Brown, S. C.; Thomson, S. A.; Veal, J. M.; Davis, D. G. NMR solution structure of a peptide nucleic acid complexed with RNA. Science 1994, 265, 777-780.
    • (1994) Science , vol.265 , pp. 777-780
    • Brown, S.C.1    Thomson, S.A.2    Veal, J.M.3    Davis, D.G.4
  • 20
    • 0029996180 scopus 로고    scopus 로고
    • Solution structure of a peptide nucleic acid-DNA duplex
    • Eriksson, M.; Nielsen, P. E. Solution Structure of a Peptide Nucleic Acid-DNA Duplex. Nat. Struct. Biol. 1996, 3 410-413.
    • (1996) Nat. Struct. Biol. , vol.3 , pp. 410-413
    • Eriksson, M.1    Nielsen, P.E.2
  • 21
    • 0029610659 scopus 로고
    • Nucleic acid triple helix formed by a peptide nucleic acid-DNA complex
    • Betts, L.; Josey, J. A.; Veal, J. M.; Jordan, S. R. A nucleic acid triple helix formed by a peptide nucleic acid-DNA complex. Science 1995, 270, 1838-1841.
    • (1995) Science , vol.270 , pp. 1838-1841
    • Betts, L.1    Josey, J.A.2    Veal, J.M.3    Jordan, S.R.A.4
  • 22
    • 0031012681 scopus 로고    scopus 로고
    • Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 å resolution. Nat
    • Rasmussen, H.; Kastrup, J. S.; Nielsen, J. N.; Nielsen, J. M.; Nielsen, P. E. Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 Å resolution. Nat. Struct. Biol. 1997, 4, 98-101.
    • (1997) Struct. Biol. , vol.4 , pp. 98-101
    • Rasmussen, H.1    Kastrup, J.S.2    Nielsen, J.N.3    Nielsen, J.M.4    Nielsen, P.E.5
  • 28
    • 0032007456 scopus 로고    scopus 로고
    • Cooperative duplex invasion of peptide nucleic acids (PNA)
    • Kurakin, A.; Larsen, H. J.; Nielsen, P. E. Cooperative Duplex Invasion of Peptide Nucleic Acids (PNA). Chem. Biol. 1998, 5, 81-89.
    • (1998) Chem. Biol. , vol.5 , pp. 81-89
    • Kurakin, A.1    Larsen, H.J.2    Nielsen, P.E.3
  • 29
    • 9044228030 scopus 로고    scopus 로고
    • Transcription-mediated binding of peptide nucleic acid (PNA) to double stranded DNA: Sequence specific suicide transcription
    • Larsen, H. J.; Nielsen, P. E. Transcription-mediated binding of peptide nucleic acid (PNA) to double stranded DNA: Sequence specific suicide transcription. Nucleic Acids Res. 1996, 24, 458-463.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 458-463
    • Larsen, H.J.1    Nielsen, P.E.2
  • 30
    • 0030035244 scopus 로고    scopus 로고
    • Enhanced peptide nucleic acid (PNA) binding to supercoiled dna: Possible implications for DNA "breathing" dynamics
    • Bentin, T.; Nielsen, P. E. Enhanced peptide nucleic acid (PNA) binding to supercoiled DNA: Possible implications for DNA "breathing" dynamics. Biochemistry 1996, 35, 8863-8869.
    • (1996) Biochemistry , vol.35 , pp. 8863-8869
    • Bentin, T.1    Nielsen, P.E.2
  • 31
    • 0029901452 scopus 로고    scopus 로고
    • Triplex formation by oligonucleotides containing novel deoxycytidine derivatives
    • Huang, C. Y.; Bi, G.; Miller, P. S. Triplex formation by oligonucleotides containing novel deoxycytidine derivatives. Nucleic Acids Res. 1996, 24, 2606-2613.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2606-2613
    • Huang, C.Y.1    Bi, G.2    Miller, P.S.3
  • 32
    • 0028796588 scopus 로고
    • Model studies directed toward a general triplex DNA recognition scheme: A novel DNA base that binds a CG base-pair in an organic solvent
    • Zimmerman, S. C.; Schmitt, P. Model Studies Directed toward a General Triplex DNA Recognition Scheme: A novel DNA base that Binds a CG Base-Pair in an Organic Solvent. J. Am. Chem. Soc. 1995, 117, 10769-10770.
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 10769-10770
    • Zimmerman, S.C.1    Schmitt, P.2
  • 33
    • 0030664802 scopus 로고    scopus 로고
    • A novel PNA monomer for recognition of thymine in triple helix structures
    • Eldrup, A. B.; Dahl, O.; Nielsen, P. E. A novel PNA monomer for recognition of thymine in triple helix structures. J. Am. Chem. Soc. 1997, 119, 11116-7.
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 11116-11117
    • Eldrup, A.B.1    Dahl, O.2    Nielsen, P.E.3
  • 35
    • 0030834244 scopus 로고    scopus 로고
    • Extended DNA-recognition repertoire of PNA
    • Wittung, P.; Nielsen, P. E.; Norden, B. Extended DNA-recognition repertoire of PNA. Biochemistry 1997, 36, 7973-7979.
    • (1997) Biochemistry , vol.36 , pp. 7973-7979
    • Wittung, P.1    Nielsen, P.E.2    Norden, B.3
  • 36
    • 0029963160 scopus 로고    scopus 로고
    • Strand displacement binding of a duplex forming homopurine PNA to a homopyrimidine duplex DNA target
    • Nielsen, P. E.; Christensen, L. Strand displacement binding of a duplex forming homopurine PNA to a homopyrimidine duplex DNA target. J. Am. Chem. Soc. 1996, 118, 2287-88.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 2287-2288
    • Nielsen, P.E.1    Christensen, L.2
  • 37
    • 0029781172 scopus 로고    scopus 로고
    • Oligonucleotides containing 2-aminoadenine and 2-thiothymine act as selectively binding complementary agents
    • Kutyavin, I. V.; Rhinehart, R. L.; Lukhtanov, E. A.; Corn, V. V.; Meyer, R. B. Jr.; Gamper, H. B. Jr. Oligonucleotides containing 2-aminoadenine and 2-thiothymine act as selectively binding complementary agents. Biochemistry 1996, 35, 11170-6.
    • (1996) Biochemistry , vol.35 , pp. 11170-11176
    • Kutyavin, I.V.1    Rhinehart, R.L.2    Lukhtanov, E.A.3    Corn, V.V.4    Meyer R.B. Jr.5    6    Gamper H.B., Jr.7
  • 40
    • 0029905694 scopus 로고    scopus 로고
    • Peptide nucleic acid pre-gel hybridization: An alternative to southern hybridization
    • Perry-O'Keefe, H.; Yao, X.-W.; Coull, J.; Fuchs, M.; Egholm, M. Peptide nucleic acid pre-gel hybridization: An alternative to southern hybridization. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 14670-14675.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 14670-14675
    • Perry-O'keefe, H.1    Yao, X.-W.2    Coull, J.3    Fuchs, M.4    Egholm, M.5
  • 41
    • 0030758618 scopus 로고    scopus 로고
    • Hybridisation based DNA screening on peptide nucleic acid (PNA) oligomer arrays
    • Weiler, J.; Gausepohl, H.; Hauser, N.; Jensen, O. N.; Hoheisel, J. D. Hybridisation based DNA screening on peptide nucleic acid (PNA) oligomer arrays Nucleic Acids Res. 1997, 25 14, 2792-2799.
    • (1997) Nucleic Acids Res. , vol.25 , Issue.14 , pp. 2792-2799
    • Weiler, J.1    Gausepohl, H.2    Hauser, N.3    Jensen, O.N.4    Hoheisel, J.D.5
  • 42
    • 0031437217 scopus 로고    scopus 로고
    • Genetic analysis by peptide nucleic acid affinity MALDI-TOF mass spectrometry
    • Griffin, T.; Tang, W. and Smith, L. M. Genetic analysis by peptide nucleic acid affinity MALDI-TOF mass spectrometry Nat. Biotechnol. 1997, 15, 1368-1370.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 1368-1370
    • Griffin, T.1    Tang, W.2    Smith, L.M.3
  • 48
    • 0029980721 scopus 로고    scopus 로고
    • Antisense properties of duplex and triplex forming PNA
    • Knudsen, H.; Nielsen, P. E. Antisense properties of duplex and triplex forming PNA. Nucleic Acids Res 1996, 24, 494-500.
    • (1996) Nucleic Acids Res , vol.24 , pp. 494-500
    • Knudsen, H.1    Nielsen, P.E.2
  • 50
    • 0029838672 scopus 로고    scopus 로고
    • In vitro transcription and translation inhibition by anti-PML/RARα and -PML peptide nucleic acid (PNA)
    • Gambacorti-Passerini, C.; Mologni, L; Bertazzoli, C.; Marchesi, E.; Grignani, F.; Nielsen, P. E. In vitro transcription and translation inhibition by anti-PML/RARα and -PML Peptide Nucleic Acid (PNA) Blood 1996, 88, 1411-1417.
    • (1996) Blood , vol.88 , pp. 1411-1417
    • Gambacorti-Passerini, C.1    Mologni, L.2    Bertazzoli, C.3    Marchesi, E.4    Grignani, F.5    Nielsen, P.E.6
  • 51
    • 0028075767 scopus 로고
    • Sequence specific transcription arrest by PNA bound to the template strand
    • Nielsen, P. E.; Egholm, M.; Buchardt, O. Sequence specific transcription Arrest by PNA bound to the template strand. Gene 1994, 149, 139-145.
    • (1994) Gene , vol.149 , pp. 139-145
    • Nielsen, P.E.1    Egholm, M.2    Buchardt, O.3
  • 52
    • 0028983888 scopus 로고
    • Inhibition of NF-kappa b specific transcriptional activation by PNA strand invasion
    • Vickers, T. A.; Griffith, M. C.; Ramasamy, K.; Risen, L. M.; Freier, S. M. Inhibition of NF-kappa B specific transcriptional activation by PNA strand invasion. Nucl. Acids Res. 1995, 23, 3003-8.
    • (1995) Nucl. Acids Res. , vol.23 , pp. 3003-3008
    • Vickers, T.A.1    Griffith, M.C.2    Ramasamy, K.3    Risen, L.M.4    Freier, S.M.5
  • 53
    • 0031984072 scopus 로고    scopus 로고
    • Trojan peptides: The penetratin system for intracellular delivery
    • Derossi, D.; Chassaing, G.; Prochiantz, A. Trojan peptides: The penetratin system for intracellular delivery. Trends Cell Biol. 1998, 8, 84-87.
    • (1998) Trends Cell Biol. , vol.8 , pp. 84-87
    • Derossi, D.1    Chassaing, G.2    Prochiantz, A.3
  • 54
    • 0029012140 scopus 로고
    • Targeting peptide nucleic acid-protein conjugates to structural features within duplex DNA
    • Norton, J. C.; Waggenspack, J. H.; Varnum, E.; Corey, D. R. Targeting Peptide Nucleic Acid-Protein conjugates to structural features within duplex DNA. Bioorg. Med. Chem. 1995, 3, 437-445.
    • (1995) Bioorg. Med. Chem. , vol.3 , pp. 437-445
    • Norton, J.C.1    Waggenspack, J.H.2    Varnum, E.3    Corey, D.R.4
  • 56
    • 0032211042 scopus 로고    scopus 로고
    • Peptide nucleic acid (PNA) is more rapidly internalized in cultured neurons when coupled to a retro-inverso delivery peptide. The antisense activity depresses the target mRNA and protein in magnocelllar oxytocin neurons
    • Aldrian-Herrada, G.; Desarmnien, M. G.; Orcel, H.; Boissin-Agasse, L.; Méry, J. Brugidou, J.; Rabié, A. A peptide nucleic acid (PNA) is more rapidly internalized in cultured neurons when coupled to a retro-inverso delivery peptide. The antisense activity depresses the target mRNA and protein in magnocelllar oxytocin neurons. Nucl. Acids Res. 1998, 26, 4910-4916.
    • (1998) Nucl. Acids Res. , vol.26 , pp. 4910-4916
    • Aldrian-Herrada, G.1    Desarmnien, M.G.2    Orcel, H.3    Boissin-Agasse, L.4    Méry, J.5    Brugidou, J.6    Rabié, A.A.7
  • 58
    • 0032478330 scopus 로고    scopus 로고
    • Inhibition of translation and bacterial growth by peptide nucleic acids (PNA) targeted to ribosomal RNA
    • Good, L.; Nielsen, P. E. Inhibition of translation and bacterial growth by peptide nucleic acids (PNA) targeted to ribosomal RNA. Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 2073-76.
    • (1998) Proc. Natl. Acad. Sci. U.s.a. , vol.95 , pp. 2073-2076
    • Good, L.1    Nielsen, P.E.2
  • 59
    • 0031979354 scopus 로고    scopus 로고
    • Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA
    • Good, L.; Nielsen, P. E. Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA. Nat. Biotechnol. 1998, 16, 355-358.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 355-358
    • Good, L.1    Nielsen, P.E.2
  • 60
    • 0029414939 scopus 로고
    • The search for missing links between self-replicating nucleic acids and the RNA world
    • James, K. D.; Ellington, A. D. The Search for Missing Links Between Self-replicating Nucleic Acids and the RNA World. Origins Life Evol. Biosphere 1995, 25, 515-30.
    • (1995) Origins Life Evol. Biosphere , vol.25 , pp. 515-530
    • James, K.D.1    Ellington, A.D.2
  • 61
    • 0027758668 scopus 로고
    • Peptide nucleic acid (PNA) a model structure for the primordial genetic material
    • Nielsen, P. E. Peptide Nucleic Acid (PNA) A model structure for the primordial genetic material. Origins Life 1993, 23, 323-327.
    • (1993) Origins Life , vol.23 , pp. 323-327
    • Nielsen, P.E.1
  • 62
    • 0029160308 scopus 로고
    • Template switching between PNA and RNA oligonucleotides
    • Böhler, C.; Nielsen, P. E.; Orgel, L. E. Template switching between PNA and RNA oligonucleotides. Nature 1995, 376, 578-581.
    • (1995) Nature , vol.376 , pp. 578-581
    • Böhler, C.1    Nielsen, P.E.2    Orgel, L.E.3
  • 63
    • 0030699122 scopus 로고    scopus 로고
    • Information transfer from peptide nucleic acid to RNA by template-directed syntheses
    • Schmidt, J.; Nielsen, P. E.; Orgel, L. Information transfer from peptide nucleic acid to RNA by template-directed syntheses. Nucleic Acids Res. 1997, 25, 4797-4802.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4797-4802
    • Schmidt, J.1    Nielsen, P.E.2    Orgel, L.3
  • 65
    • 0025008851 scopus 로고
    • Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet
    • Piccirilli, J. A.; Krauch, T. Moroney, S. E.; Benner, S. A. Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet Nature 1990, 343, 33-7.
    • (1990) Nature , vol.343 , pp. 33-37
    • Piccirilli, J.A.1    Krauch, T.2    Moroney, S.E.3    Benner, S.A.4
  • 66
    • 0031804028 scopus 로고    scopus 로고
    • DNA nanotechnology: Novel DNA constructions
    • Seeman, N. C. DNA nanotechnology: novel DNA constructions. Annu. Rev. Biophys. Biomol. Struct. 1998, 27, 225-48.
    • (1998) Annu. Rev. Biophys. Biomol. Struct. , vol.27 , pp. 225-248
    • Seeman, N.C.1
  • 67
    • 0031799177 scopus 로고    scopus 로고
    • Selective and stable DNA base pairing without hydrogen bonds
    • Matray, T. J.; Kool, E. T. Selective and Stable DNA Base Pairing without Hydrogen Bonds. J. Am. Chem. Soc. 1998, 120, 6191-2.
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 6191-6192
    • Matray, T.J.1    Kool, E.T.2
  • 68
    • 0029937476 scopus 로고    scopus 로고
    • A flexible and positively charged PNA analogue with an ethylene-linker to the nucleobase: Synthesis and hybridization properties
    • Hyrup, B.; Egholm, M.; Buchardt, O.; Nielsen, P. E. A flexible and positively charged PNA analogue with an ethylene-linker to the nucleobase: Synthesis and hybridization properties. Bioorg. Med. Chem. Lett. 1996, 6, 1083-1088.
    • (1996) Bioorg. Med. Chem. Lett. , vol.6 , pp. 1083-1088
    • Hyrup, B.1    Egholm, M.2    Buchardt, O.3    Nielsen, P.E.4
  • 69
    • 0029905179 scopus 로고    scopus 로고
    • Peptide nucleic acids (PNA) containing thymine monomers derived from chiral amino acids.: Hybridization and solubility properties of d-lysine PNA
    • Haaima, G.; Lohse, A.; Buchardt, O.; Nielsen, P. E. Peptide Nucleic Acids (PNA) containing thymine monomers derived from chiral amino acids.: Hybridization and solubility properties of d-lysine PNA. Angew. Chem. 1996, 35, 1939-1941.
    • (1996) Angew. Chem. , vol.35 , pp. 1939-1941
    • Haaima, G.1    Lohse, A.2    Buchardt, O.3    Nielsen, P.E.4
  • 72
    • 0032518178 scopus 로고    scopus 로고
    • Synthesis and evaluation of some properties of chimeric oligomers containing PNA and phosphono-PNA residues
    • Efimov, V. A.; Choob, M. V.; Buryakova, A. A.; Kalinkina A. L.; Chakhmakhcheva, O. G. Synthesis and evaluation of some properties of chimeric oligomers containing PNA and phosphono-PNA residues. Nucleic Acids Res. 1998, 26, 566-575.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 566-575
    • Efimov, V.A.1    Choob, M.V.2    Buryakova, A.A.3    Kalinkina A, L.4    Chakhmakhcheva, O.G.5
  • 73
    • 0027986543 scopus 로고
    • Structure - Activity studies of the binding of modified peptide nucleic acids (PNA) to DNA
    • Hyrup, B.; Egholm, M.; Nielsen, P. E.; Wittung, P.; Nordén, B.; Buchardt, O.: Structure - activity studies of the binding of modified peptide nucleic acids (PNA) to DNA. J. Am. Chem. Soc. 1994, 116, 7964-7970.
    • (1994) J. Am. Chem. Soc. , vol.116 , pp. 7964-7970
    • Hyrup, B.1    Egholm, M.2    Nielsen, P.E.3    Wittung, P.4    Nordén, B.5    Buchardt, O.6
  • 74
    • 0030780913 scopus 로고    scopus 로고
    • Increased DNA binding and sequence discrimination of PNA upon incorporation of diaminopurine
    • Haaima, G.; Hansen, H. F.; Christensen, L.; Dahl, O.; Nielsen, P. E. Increased DNA binding and sequence discrimination of PNA upon incorporation of Diaminopurine. Nucleic Acids Res. 1997, 25, 4639-4643.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4639-4643
    • Haaima, G.1    Hansen, H.F.2    Christensen, L.3    Dahl, O.4    Nielsen, P.E.5
  • 75
    • 0000061743 scopus 로고    scopus 로고
    • 2-aminopurine peptide nucleic acids (2-apPNA): Intrinsic fluorescent PNA analogues for probing PNA-DNA interaction dynamics
    • Gangamani, B.; Kumar, V. A.; Ganesh, K. N. 2-aminopurine peptide nucleic acids (2-apPNA): intrinsic fluorescent PNA analogues for probing PNA-DNA interaction dynamics. Chem. Commun. 1997, 1913-1914.
    • (1997) Chem. Commun. , pp. 1913-1914
    • Gangamani, B.1    Kumar, V.A.2    Ganesh, K.N.3
  • 76
    • 0028928953 scopus 로고
    • Efficient pH independent sequence specific DNA binding by pseudoisocytosine-containing bis-PNA
    • Egholm, M.; Christensen, L.; Dueholm, K.; Buchardt, O.; Coull, J.; Nielsen, P. E. Efficient pH independent sequence specific DNA binding by pseudoisocytosine-containing bis-PNA. Nucleic Acids Res. 1995, 23, 217-222.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 217-222
    • Egholm, M.1    Christensen, L.2    Dueholm, K.3    Buchardt, O.4    Coull, J.5    Nielsen, P.E.6


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