Endosome trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates

Journal of Controlled Release

Volumn 110, Issue 3, 2006, Pages 595-604

  Abes, Saïd ^a   Williams, Donna ^b   Prevot, Paul ^a   Thierry, Alain ^a   Gait, Michael J ^b   Lebleu, Bernard ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Conjugation; Endocytosis; Oligolysine; PNA; Splicing correction

Indexed keywords

CELLS; CONTROLLED DRUG DELIVERY; CYTOLOGY; OLIGOMERS; SUGAR (SUCROSE);

ENDOCYTOSIS; OLIGOLYSINE; PNA; SPLICING CORRECTION;

NUCLEIC ACIDS;

LYSINE; OLIGOLYSINE; OLIGONUCLEOTIDE; PEPTIDE NUCLEIC ACID; STERIC BLOCKING OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; CONJUGATION; CONTROLLED STUDY; CYTOPLASM VESICLE; ENDOCYTOSIS; ENDOSOME; GENE DELIVERY SYSTEM; HUMAN; HUMAN CELL; INTERNALIZATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REPORTER GENE; RNA SPLICING; TEMPERATURE DEPENDENCE;

CELL MEMBRANE; ENDOSOMES; HELA CELLS; HUMANS; PEPTIDE NUCLEIC ACIDS; RNA SPLICING;

EID: 31544458695     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.10.026     Document Type: Article

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