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Volumn 14, Issue 11, 2010, Pages 1259-1271

Targeting tryptophan hydroxylase 2 in affective disorder

Author keywords

Affective disorders; Polymorphism; Sensitivity to psychotropic drugs; Tryptophan hydroxylase 2

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; FLUOXETINE; LITHIUM; MONOAMINE OXIDASE INHIBITOR; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; TRYPTOPHAN; TRYPTOPHAN HYDROXYLASE; TRYPTOPHAN HYDROXYLASE 2;

EID: 77958054867     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.2010.524208     Document Type: Review
Times cited : (32)

References (149)
  • 1
    • 0032145210 scopus 로고    scopus 로고
    • The spectrum of behavior influenced by serotonin
    • Lucki I. The spectrum of behavior influenced by serotonin. Biol Psychiatry 1998;44:151-162
    • (1998) Biol Psychiatry , vol.44 , pp. 151-162
    • Lucki, I.1
  • 2
    • 33646380088 scopus 로고    scopus 로고
    • From genes to aggressive behavior: The role of serotonergic system
    • Popova NK. From genes to aggressive behavior: the role of serotonergic system. Bioessays 2006;28:495-503
    • (2006) Bioessays , vol.28 , pp. 495-503
    • Popova, N.K.1
  • 3
    • 54049124260 scopus 로고    scopus 로고
    • Dietary amino acids and brain serotonin function; Implications for stress-related affective changes
    • Markus CR. Dietary amino acids and brain serotonin function; implications for stress-related affective changes. Neuromol Med 2008;10:247-258
    • (2008) Neuromol Med , vol.10 , pp. 247-258
    • Markus, C.R.1
  • 4
    • 0000587671 scopus 로고
    • The serotonin hypothesis of major depression
    • Bloom EE, Kupfer NN, editors, The fourth generation of progress. Raven Press, New York
    • Maes M, Meltzer HY. The serotonin hypothesis of major depression. In: Bloom EE, Kupfer NN, editors, Psychopharmacology. The fourth generation of progress. Raven Press, New York; 1995. p. 933-944
    • (1995) Psychopharmacology , pp. 933-944
    • Maes, M.1    Meltzer, H.Y.2
  • 6
    • 0033789664 scopus 로고    scopus 로고
    • Clinical and physiological consequences of rapid tryptophan depletion
    • Moore P, Landolt H-P, Seifritz E, et al. Clinical and physiological consequences of rapid tryptophan depletion. Neuropsychopharmacology 2000;23:601-622
    • (2000) Neuropsychopharmacology , vol.23 , pp. 601-622
    • Moore, P.1    Landolt, H.-P.2    Seifritz, E.3
  • 7
    • 77958027732 scopus 로고
    • Cerebrospinal fluid levels of 5-hydroxyindoleacetic acid in psychiatric disorders: A critical assessment
    • Barchas J, Usdin E, editors, Academic Press, New York
    • Wilk S. Cerebrospinal fluid levels of 5-hydroxyindoleacetic acid in psychiatric disorders: a critical assessment. In: Barchas J, Usdin E, editors, Serotonin and behavior. Academic Press, New York; 1973. p. 483-486
    • (1973) Serotonin and Behavior , pp. 483-486
    • Wilk, S.1
  • 8
    • 0016022901 scopus 로고
    • Serotonin and 5-hydroxyindoleacetic acid in discrete areas of the brainstem of suicide victims and control patients
    • Lloyd KG, Farley IJ, Deck JH, Hornykiewicz O. Serotonin and 5-hydroxyindoleacetic acid in discrete areas of the brainstem of suicide victims and control patients. Adv Biochem Psychopharmacol 1974;11:387-397
    • (1974) Adv Biochem Psychopharmacol , vol.11 , pp. 387-397
    • Lloyd, K.G.1    Farley, I.J.2    Deck, J.H.3    Hornykiewicz, O.4
  • 9
    • 0016018684 scopus 로고
    • Towards a biochemical classification of depression
    • Van Praag HM. Towards a biochemical classification of depression. Adv Biochem Psychopharmacol 1974;11:357-368
    • (1974) Adv Biochem Psychopharmacol , vol.11 , pp. 357-368
    • Van Praag, H.M.1
  • 10
    • 0020018112 scopus 로고
    • Human aggression and suicide: Their relationship to neuropsychiatric diagnoses and serotonin metabolism
    • Brown GL, Goodwin FK, Bunney WE. Human aggression and suicide: their relationship to neuropsychiatric diagnoses and serotonin metabolism. Adv Biochem Psychopharmacol 1982;34:287-307
    • (1982) Adv Biochem Psychopharmacol , vol.34 , pp. 287-307
    • Brown, G.L.1    Goodwin, F.K.2    Bunney, W.E.3
  • 11
    • 77958025139 scopus 로고
    • Cerebrospinal fluid 5HIAA and tryptophan in depression and suicide
    • Schlossberger HG Kochen W Linzen B Steinhart H editors, Berlin Walter de Gruyter
    • Banki CM, Arato M, Papp S, Kurcz M. Cerebrospinal fluid 5HIAA and tryptophan in depression and suicide. In: Schlossberger HG, Kochen W, Linzen B, Steinhart H, editors, Progress in tryptophan and serotonin research, Berlin Walter de Gruyter; 1984. p. 397-400
    • (1984) Progress in Tryptophan and Serotonin Research , pp. 397-400
    • Banki, C.M.1    Arato, M.2    Papp, S.3    Kurcz, M.4
  • 12
    • 0023645097 scopus 로고
    • A single gene codes for aromatic L-amino acid decarboxylase in both neuronal and non neuronal tissues
    • Albert VR, Allen JM, Joh TH. A single gene codes for aromatic L-amino acid decarboxylase in both neuronal and non neuronal tissues. J Biol Chem 1987;262:9404-9411
    • (1987) J Biol Chem , vol.262 , pp. 9404-9411
    • Albert, V.R.1    Allen, J.M.2    Joh, T.H.3
  • 13
    • 0032852842 scopus 로고    scopus 로고
    • Tetrahydopterin-dependent amino acid hydroxylases
    • Fitzpatrick PF. Tetrahydopterin-dependent amino acid hydroxylases. Annu Rev Biochem 1999;68:355-381
    • (1999) Annu Rev Biochem , vol.68 , pp. 355-381
    • Fitzpatrick, P.F.1
  • 14
    • 0345492036 scopus 로고    scopus 로고
    • Mechanism of aromatic amino acid hydroxylation
    • Fitzpatrick PF. Mechanism of aromatic amino acid hydroxylation. Biochemistry 2003;42:14083-14091
    • (2003) Biochemistry , vol.42 , pp. 14083-14091
    • Fitzpatrick, P.F.1
  • 15
    • 0023946281 scopus 로고
    • Sequence of two mRNAs encoding active rat tryptophan hydroxylase
    • Darmon MC, Guibert B, Leviel V, et al. Sequence of two mRNAs encoding active rat tryptophan hydroxylase. J Neurochem 1988;51:312-316
    • (1988) J Neurochem , vol.51 , pp. 312-316
    • Darmon, M.C.1    Guibert, B.2    Leviel, V.3
  • 16
    • 0024998716 scopus 로고
    • Characterization and chromosomal mapping of a cDNA encoding TPH from a mouse mastocytoma cell line
    • Stoll J, Kozak CA, Goldman D. Characterization and chromosomal mapping of a cDNA encoding TPH from a mouse mastocytoma cell line. Genomics 1990;7:88-96
    • (1990) Genomics , vol.7 , pp. 88-96
    • Stoll, J.1    Kozak, C.A.2    Goldman, D.3
  • 18
    • 0037414862 scopus 로고    scopus 로고
    • Synthesis of serotonin by a second thryptophan hydroxylase isoform
    • Walther DJ, Peter J-U, Bashammakh S, et al. Synthesis of serotonin by a second thryptophan hydroxylase isoform. Science 2003;299:76
    • (2003) Science , vol.299 , pp. 76
    • Walther, D.J.1    Peter, J.-U.2    Bashammakh, S.3
  • 19
    • 0141922899 scopus 로고    scopus 로고
    • A unique central tryptophan hydroxylase isoform
    • Walther D, Bader M. A unique central tryptophan hydroxylase isoform. Biochem Pharmacol 2003;66:1673-1680
    • (2003) Biochem Pharmacol , vol.66 , pp. 1673-1680
    • Walther, D.1    Bader, M.2
  • 20
    • 30744436805 scopus 로고    scopus 로고
    • Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2
    • Zhang X, Beaulieu J-M, Gainetdinov RR, Caron MG. Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2. Cell Mol Life Sci 2006;63:6-11
    • (2006) Cell Mol Life Sci , vol.63 , pp. 6-11
    • Zhang, X.1    Beaulieu, J.-M.2    Gainetdinov, R.R.3    Caron, M.G.4
  • 21
    • 33646337605 scopus 로고
    • Brain and peripheral effects of serotonin on thermoregulation
    • Popova NK, Konusova AV. Brain and peripheral effects of serotonin on thermoregulation. Biogenic Amines 1985;3:125-134
    • (1985) Biogenic Amines , vol.3 , pp. 125-134
    • Popova, N.K.1    Konusova, A.V.2
  • 22
    • 0013986153 scopus 로고
    • P-Chlorophenylalanine: A specific depletor of brain serotonin
    • Koe BK, Weissman A. p-Chlorophenylalanine: a specific depletor of brain serotonin. J Pharmacol Exp Ther 1966;154:499-516
    • (1966) J Pharmacol Exp Ther , vol.154 , pp. 499-516
    • Koe, B.K.1    Weissman, A.2
  • 23
    • 0141757425 scopus 로고    scopus 로고
    • Serotonin synthesis inhibition in olivo-cerebellar system attenuates harmaline-induced tremor in Swiss albino mice
    • Mehta H, Saravanan KS, Mohanakumar KP. Serotonin synthesis inhibition in olivo-cerebellar system attenuates harmaline-induced tremor in Swiss albino mice. Behav Brain Res 2003;145:31-36
    • (2003) Behav Brain Res , vol.145 , pp. 31-36
    • Mehta, H.1    Saravanan, K.S.2    Mohanakumar, K.P.3
  • 24
    • 28844493032 scopus 로고    scopus 로고
    • Specificity and efficacy of noradrenaline, serotonin depletion in discrete brain areas of Swiss mice by neurotoxins
    • Dailly E, Chenu F, Petit-Demoulière B, Bourin M. Specificity and efficacy of noradrenaline, serotonin depletion in discrete brain areas of Swiss mice by neurotoxins. J Neurosci Methods 2006;150:111-115
    • (2006) J Neurosci Methods , vol.150 , pp. 111-115
    • Dailly, E.1    Chenu, F.2    Petit-Demoulière, B.3    Bourin, M.4
  • 25
    • 28744453389 scopus 로고    scopus 로고
    • Central serotonin depletion affects rat brain areas differently: A qualitative and quantitative comparison between different treatment schemes
    • Kornum BR, Licht CL, Weikop P, et al. Central serotonin depletion affects rat brain areas differently: a qualitative and quantitative comparison between different treatment schemes. Neurosci Lett 2006;392:129-134
    • (2006) Neurosci Lett , vol.392 , pp. 129-134
    • Kornum, B.R.1    Licht, C.L.2    Weikop, P.3
  • 26
    • 49749117799 scopus 로고    scopus 로고
    • Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice
    • Gutknecht L, Waider J, Kraft S, et al. Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice. J Neural Transm 2008;115:1127-1132
    • (2008) J Neural Transm , vol.115 , pp. 1127-1132
    • Gutknecht, L.1    Waider, J.2    Kraft, S.3
  • 27
    • 54849404294 scopus 로고    scopus 로고
    • Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants
    • Savelieva KV, Zhao S, Pogorelov VM, et al. Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants. PLoS ONE 2008;3:e3301
    • (2008) PLoS ONE , vol.3
    • Savelieva, K.V.1    Zhao, S.2    Pogorelov, V.M.3
  • 28
    • 67649854385 scopus 로고    scopus 로고
    • Growth retardation and altered autonomic control in mice lacking brain serotonin
    • Alenina N, Kikic D, Todiras M, et al. Growth retardation and altered autonomic control in mice lacking brain serotonin. Proc Natl Acad Sci USA 2009;106:10333-10337
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 10333-10337
    • Alenina, N.1    Kikic, D.2    Todiras, M.3
  • 29
    • 33750725388 scopus 로고    scopus 로고
    • Analysis of tryptophan hydroxylase i and II mRNA expression in the human brain: A post-mortem study
    • Zill P, Buttner A, Eisenmenger W, et al. Analysis of tryptophan hydroxylase I and II mRNA expression in the human brain: a post-mortem study. J Psychiatr Res 2007;41:168-173
    • (2007) J Psychiatr Res , vol.41 , pp. 168-173
    • Zill, P.1    Buttner, A.2    Eisenmenger, W.3
  • 30
    • 77952690277 scopus 로고    scopus 로고
    • Simultaneous analysis of serotonin transporter, thryptophan hydroxylase 1 and 2 gene expression in the ventral prefrontal cortex of suicide victims
    • Perroud N, Neidhart E, Petit B, et al. Simultaneous analysis of serotonin transporter, thryptophan hydroxylase 1 and 2 gene expression in the ventral prefrontal cortex of suicide victims. Am J Med Genet B 2010;153B:909-918
    • (2010) Am J Med Genet B , vol.153 B , pp. 909-918
    • Perroud, N.1    Neidhart, E.2    Petit, B.3
  • 31
    • 34347340642 scopus 로고    scopus 로고
    • Developmental role of tryptophan hydroxylase in the nervous system
    • Nakamura K, Hasegawa H. Developmental role of tryptophan hydroxylase in the nervous system. Mol Neurobiol 2007;35:45-54
    • (2007) Mol Neurobiol , vol.35 , pp. 45-54
    • Nakamura, K.1    Hasegawa, H.2
  • 32
    • 40349096750 scopus 로고    scopus 로고
    • Stress upregulates TPH1 but not TPH2 mRNA in the rat dorsal raphe nucleus: Identification of two TPH2 mRNA splice variants
    • Abumaria N, Ribic A, Anacker C, et al. Stress upregulates TPH1 but not TPH2 mRNA in the rat dorsal raphe nucleus: identification of two TPH2 mRNA splice variants. Cell Mol Neurobiol 2008;28:331-342
    • (2008) Cell Mol Neurobiol , vol.28 , pp. 331-342
    • Abumaria, N.1    Ribic, A.2    Anacker, C.3
  • 33
    • 0018268297 scopus 로고
    • Behavioral despair in rats: A new model sensitive to antidepressant treatments
    • Porsolt R, Anton G, Blavett N, Jalfre M. Behavioral despair in rats: a new model sensitive to antidepressant treatments. Eur J Pharmacol 1978;47:379-391
    • (1978) Eur J Pharmacol , vol.47 , pp. 379-391
    • Porsolt, R.1    Anton, G.2    Blavett, N.3    Jalfre, M.4
  • 34
    • 0017618768 scopus 로고
    • Depression: A new animal model sensitive to antidepressant treatments
    • Porsolt RD, Le Pichon M, Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature 1977;266:730-732
    • (1977) Nature , vol.266 , pp. 730-732
    • Porsolt, R.D.1    Le Pichon, M.2    Jalfre, M.3
  • 35
    • 0023915698 scopus 로고
    • Is the forced swimming test a suitable model for revealing antidepressant activity?
    • Borsini F, Meli A. Is the forced swimming test a suitable model for revealing antidepressant activity? Psychopharmacol 1988;94:147-160
    • (1988) Psychopharmacol , vol.94 , pp. 147-160
    • Borsini, F.1    Meli, A.2
  • 36
    • 0025057433 scopus 로고
    • Animal models of depression: An overview
    • Willner P. Animal models of depression: an overview. Pharmacol Ther 1990;45:425-455
    • (1990) Pharmacol Ther , vol.45 , pp. 425-455
    • Willner, P.1
  • 37
    • 0036328118 scopus 로고    scopus 로고
    • The validity of animal models of predisposition to depression
    • Willner P, Mitchell PJ. The validity of animal models of predisposition to depression. Behav Pharmacol 2002;13:169-188
    • (2002) Behav Pharmacol , vol.13 , pp. 169-188
    • Willner, P.1    Mitchell, P.J.2
  • 38
    • 39549108481 scopus 로고    scopus 로고
    • Role of GSK3beta in behavioral abnormalities induced by serotonin deficiency
    • Beaulieu J-M, Zhang X, Rodriguiz RM, et al. Role of GSK3beta in behavioral abnormalities induced by serotonin deficiency. Proc Natl Acad Sci USA 2008;105:1333-1338
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 1333-1338
    • Beaulieu, J.-M.1    Zhang, X.2    Rodriguiz, R.M.3
  • 39
    • 3042722258 scopus 로고    scopus 로고
    • Tryptophan hydroxylase-2 controls brain serotonin synthesis
    • Zhang X, Beaulieu J-M, Sotnikova TD, et al. Tryptophan hydroxylase-2 controls brain serotonin synthesis. Science 2004;305:217
    • (2004) Science , vol.305 , pp. 217
    • Zhang, X.1    Beaulieu, J.-M.2    Sotnikova, T.D.3
  • 40
    • 33645103418 scopus 로고    scopus 로고
    • Mouse tryptophan hydroxylase isoform 2 and the role of proline 447 in enzyme function
    • Sakowski SA, Geddes TJ, Kuhn DM. Mouse tryptophan hydroxylase isoform 2 and the role of proline 447 in enzyme function. J Neurochem 2006;96:758-765
    • (2006) J Neurochem , vol.96 , pp. 758-765
    • Sakowski, S.A.1    Geddes, T.J.2    Kuhn, D.M.3
  • 41
    • 28044463376 scopus 로고    scopus 로고
    • Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strains
    • Kulikov AV, Osipova DV, Naumenko VS, Popova NK. Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strains. Genes Brain Behav 2005;4:482-485
    • (2005) Genes Brain Behav , vol.4 , pp. 482-485
    • Kulikov, A.V.1    Osipova, D.V.2    Naumenko, V.S.3    Popova, N.K.4
  • 42
    • 37349007261 scopus 로고    scopus 로고
    • The C1473G polymorphism in gene tph2 is the main factor mediating the genetically defined variability of tryptophan hydroxylase-2 activity in the mouse brain
    • Kulikov AV, Osipova DV, Popova NK. The C1473G polymorphism in gene tph2 is the main factor mediating the genetically defined variability of tryptophan hydroxylase-2 activity in the mouse brain. Russ J Genet 2007;43:1408-1412
    • (2007) Russ J Genet , vol.43 , pp. 1408-1412
    • Kulikov, A.V.1    Osipova, D.V.2    Popova, N.K.3
  • 43
    • 65949087865 scopus 로고    scopus 로고
    • C1473G polymorphism in mouse tph2 gene is linked to tryptophan hydroxylase-2 activity in the brain, intermale aggression, and depressive-like behavior in the forced swim test
    • Osipova DV, Kulikov AV, Popova NK. C1473G polymorphism in mouse tph2 gene is linked to tryptophan hydroxylase-2 activity in the brain, intermale aggression, and depressive-like behavior in the forced swim test. J Neurosci Res 2009;87:1168-1174
    • (2009) J Neurosci Res , vol.87 , pp. 1168-1174
    • Osipova, D.V.1    Kulikov, A.V.2    Popova, N.K.3
  • 44
    • 77955090863 scopus 로고    scopus 로고
    • Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6J and BALB/cJ congenic mice
    • Siesser WB, Zhang X, Jacobsen JPR, et al. Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6J and BALB/cJ congenic mice. Neurosci Lett 2010;481:6-11
    • (2010) Neurosci Lett , vol.481 , pp. 6-11
    • Siesser, W.B.1    Zhang, X.2    Jacobsen, J.P.R.3
  • 45
    • 38049004434 scopus 로고    scopus 로고
    • The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains
    • Tenner K, Qadri F, Bert B, et al. The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains. Neurosci Lett 2008;431:21-25
    • (2008) Neurosci Lett , vol.431 , pp. 21-25
    • Tenner, K.1    Qadri, F.2    Bert, B.3
  • 46
    • 0030552728 scopus 로고    scopus 로고
    • Association between intermale aggression and genetically defined tryptophan hydroxylase activity in the mouse brain
    • Kulikov AV, Popova NK. Association between intermale aggression and genetically defined tryptophan hydroxylase activity in the mouse brain. Aggr Behav 1996;22:111-117
    • (1996) Aggr Behav , vol.22 , pp. 111-117
    • Kulikov, A.V.1    Popova, N.K.2
  • 47
    • 77954321151 scopus 로고    scopus 로고
    • Distribution of the C1473G polymorphism in tryptophan hydroxylase 2 gene in laboratory and wild mice
    • Osipova DV, Kulikov AV, Mekada K, et al. Distribution of the C1473G polymorphism in tryptophan hydroxylase 2 gene in laboratory and wild mice. Genes Brain Behav 2010;9:537-543
    • (2010) Genes Brain Behav , vol.9 , pp. 537-543
    • Osipova, D.V.1    Kulikov, A.V.2    Mekada, K.3
  • 48
    • 0025908406 scopus 로고
    • Serotonin metabolism and serotonergic receptors in Norway rats selected for low aggressiveness to man
    • Popova NK, Kulikov AV, Nikulina EM, et al. Serotonin metabolism and serotonergic receptors in Norway rats selected for low aggressiveness to man. Aggr Behav 1991;17:207-213
    • (1991) Aggr Behav , vol.17 , pp. 207-213
    • Popova, N.K.1    Kulikov, A.V.2    Nikulina, E.M.3
  • 49
    • 0026322359 scopus 로고
    • Evidence for the involvement of central serotonin in mechanism of domestication of silver foxes
    • Popova NK, Voitenko NN, Kulikov AV, Avgustinovich DF. Evidence for the involvement of central serotonin in mechanism of domestication of silver foxes. Pharmacol Biochem Behav 1991;40:751-756
    • (1991) Pharmacol Biochem Behav , vol.40 , pp. 751-756
    • Popova, N.K.1    Voitenko, N.N.2    Kulikov, A.V.3    Avgustinovich, D.F.4
  • 50
    • 18744382663 scopus 로고    scopus 로고
    • Brain serotonin in genetically defined defensive behavior
    • Millar R, Ivanitsky AM, Balaban PM, editors, Harwood Press, New York
    • Popova NK. Brain serotonin in genetically defined defensive behavior. In: Millar R, Ivanitsky AM, Balaban PM, editors, Complex brain functions: conceptual advances in Russian neuroscience. Harwood Press, New York; 1999. p. 307-329
    • (1999) Complex Brain Functions: Conceptual Advances in Russian Neuroscience , pp. 307-329
    • Popova, N.K.1
  • 51
    • 17944373029 scopus 로고    scopus 로고
    • Ethological strategies for defense in animals and humans: Their role in some psychiatric disorders
    • Dixon AK. Ethological strategies for defense in animals and humans: their role in some psychiatric disorders. Br J Med Psychol 1998;71:417-445
    • (1998) Br J Med Psychol , vol.71 , pp. 417-445
    • Dixon, A.K.1
  • 53
    • 0028997781 scopus 로고
    • On the role of brain serotonin in expression of genetic predisposition to catalepsy in animal models
    • Popova N, Kulikov A. On the role of brain serotonin in expression of genetic predisposition to catalepsy in animal models. Am J Med Genet (Neuropsychiatric Genetics) 1995;60:214-220
    • (1995) Am J Med Genet (Neuropsychiatric Genetics) , vol.60 , pp. 214-220
    • Popova, N.1    Kulikov, A.2
  • 54
    • 0028965041 scopus 로고
    • Correlation between tryptophan hydroxylase activity in the brain and predisposition to pinch-induced catalepsy in mice
    • Kulikov A, Kozlachkova E, Kudryavtseva N, Popova N. Correlation between tryptophan hydroxylase activity in the brain and predisposition to pinch-induced catalepsy in mice. Pharmacol Biochem Behav 1995;50:431-435
    • (1995) Pharmacol Biochem Behav , vol.50 , pp. 431-435
    • Kulikov, A.1    Kozlachkova, E.2    Kudryavtseva, N.3    Popova, N.4
  • 55
    • 0026465006 scopus 로고
    • The activity of tryptophan hydroxylase in brain of hereditary predisposed to catalepsy rats
    • Kulikov A, Kozlachkova E, Popova N. The activity of tryptophan hydroxylase in brain of hereditary predisposed to catalepsy rats. Pharmacol Biochem Behav 1992;43:999-1003
    • (1992) Pharmacol Biochem Behav , vol.43 , pp. 999-1003
    • Kulikov, A.1    Kozlachkova, E.2    Popova, N.3
  • 56
    • 42549108377 scopus 로고    scopus 로고
    • The genetic cataleptic (GC) rat strain as a model of depressive disorders
    • Kaluev A, editor, Nova Science Publishers, New York
    • Kulikov AV, Kolpakov VG, Popova NK. The genetic cataleptic (GC) rat strain as a model of depressive disorders. In: Kaluev A, editor, Animal models in biological psychiatry. Nova Science Publishers, New York; 2006. p. 59-73
    • (2006) Animal Models in Biological Psychiatry , pp. 59-73
    • Kulikov, A.V.1    Kolpakov, V.G.2    Popova, N.K.3
  • 57
    • 77954335850 scopus 로고    scopus 로고
    • Genetic control of catalepsy in mice
    • Torres S, Martin M, editors, Nova Publishers, New York
    • Kulikov AV, Popova NK. Genetic control of catalepsy in mice. In: Torres S, Martin M, editors, Genetic predisposition to disease. Nova Publishers, New York; 2008. p. 215-236
    • (2008) Genetic Predisposition to Disease , pp. 215-236
    • Kulikov, A.V.1    Popova, N.K.2
  • 58
    • 27844581257 scopus 로고    scopus 로고
    • Tryptophan hydroxylase 2 gene expression and promoter polymorphisms in bipolar disorder and schizophrenia
    • De Luca V, Likhodi O, Van Tol HH, et al. Tryptophan hydroxylase 2 gene expression and promoter polymorphisms in bipolar disorder and schizophrenia. Psychopharmacol 2005;183:378-382
    • (2005) Psychopharmacol , vol.183 , pp. 378-382
    • De Luca, V.1    Likhodi, O.2    Van Tol, H.H.3
  • 59
    • 33645017000 scopus 로고    scopus 로고
    • Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: Major depression and suicide
    • Bach-Mizrachi H, Underwood MD, Kassir SA, et al. Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide. Neuropsychopharmacol 2006;31:814-824
    • (2006) Neuropsychopharmacol , vol.31 , pp. 814-824
    • Bach-Mizrachi, H.1    Underwood, M.D.2    Kassir, S.A.3
  • 60
    • 42349117001 scopus 로고    scopus 로고
    • Evaluated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressive suicides
    • Bach-Mizrachi H, Underwood MD, Tin A, et al. Evaluated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressive suicides. Mol Psychiatry 2008;13:507-513
    • (2008) Mol Psychiatry , vol.13 , pp. 507-513
    • Bach-Mizrachi, H.1    Underwood, M.D.2    Tin, A.3
  • 61
    • 33646684688 scopus 로고    scopus 로고
    • Increased tryptophan hydroxylase immunoreactivity in the dorsal raphe nucleus of alcohol-dependent, depressive suicide subjects is restricted to the dorsal subnucleus
    • Bonkale WL, Turecki G, Austin MC. Increased tryptophan hydroxylase immunoreactivity in the dorsal raphe nucleus of alcohol-dependent, depressive suicide subjects is restricted to the dorsal subnucleus. Synapse 2006;60:81-85
    • (2006) Synapse , vol.60 , pp. 81-85
    • Bonkale, W.L.1    Turecki, G.2    Austin, M.C.3
  • 62
    • 30344466342 scopus 로고    scopus 로고
    • Gene expression of tryptophan hydroxylase 2 in post-mortem brain of suicide subjects
    • De Luca V, Likhodi O, Van Tol HH, et al. Gene expression of tryptophan hydroxylase 2 in post-mortem brain of suicide subjects. Int J Neuropsychopharmacol 2006;9:21-25
    • (2006) Int J Neuropsychopharmacol , vol.9 , pp. 21-25
    • De Luca, V.1    Likhodi, O.2    Van Tol, H.H.3
  • 63
    • 22344447846 scopus 로고    scopus 로고
    • Postmortem pariantal cortex TPH2 expression is not altered in schizophrenic, unipolar-depressed, and bipolar patients vs control subjects
    • Shamir A, Shaltiel G, Levi I, et al. Postmortem pariantal cortex TPH2 expression is not altered in schizophrenic, unipolar-depressed, and bipolar patients vs control subjects. J Mol Neurosci 2005;26:33-37
    • (2005) J Mol Neurosci , vol.26 , pp. 33-37
    • Shamir, A.1    Shaltiel, G.2    Levi, I.3
  • 64
    • 34548437582 scopus 로고    scopus 로고
    • Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese
    • Lin YM, Chao SC, Chen TM, et al. Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese. Arch Gen Psychiatry 2007;64:1015-1024
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 1015-1024
    • Lin, Y.M.1    Chao, S.C.2    Chen, T.M.3
  • 65
    • 35848970093 scopus 로고    scopus 로고
    • Characterization of a functional promoter polymorphism of the human tryptophan hydroxylase 2 gene in serotonin raphe neurons
    • Scheuch K, Lautenschlager M, Grohmann M, et al. Characterization of a functional promoter polymorphism of the human tryptophan hydroxylase 2 gene in serotonin raphe neurons. Biol Psychiatry 2007;62:1288-1294
    • (2007) Biol Psychiatry , vol.62 , pp. 1288-1294
    • Scheuch, K.1    Lautenschlager, M.2    Grohmann, M.3
  • 66
    • 34848916457 scopus 로고    scopus 로고
    • Regulation of tryptophan hydroxylase-2 gene expression by a bipartite RE-1 silencer of transcription/neuron restrictive silencing factor (REST/NRSF) binding motif
    • Patel PD, Bochar DA, Turner DL, et al. Regulation of tryptophan hydroxylase-2 gene expression by a bipartite RE-1 silencer of transcription/neuron restrictive silencing factor (REST/NRSF) binding motif. J Biol Chem 2007;282:26717-26724
    • (2007) J Biol Chem , vol.282 , pp. 26717-26724
    • Patel, P.D.1    Bochar, D.A.2    Turner, D.L.3
  • 67
    • 37749008643 scopus 로고    scopus 로고
    • Functional characterization of the human TPH2 5¢ regulatory region: Untranslated region and polymorphism modulate gene expression in vitro
    • Chen GL, Vallender EJ, Miller GM. Functional characterization of the human TPH2 5¢ regulatory region: untranslated region and polymorphism modulate gene expression in vitro. Hum Genet 2008;122:645-657
    • (2008) Hum Genet , vol.122 , pp. 645-657
    • Chen, G.L.1    Vallender, E.J.2    Miller, G.M.3
  • 68
    • 11344282078 scopus 로고    scopus 로고
    • Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression
    • Zhang X, Gainetdinov RR, Beaulieu J-M, et al. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 2005;45:11-16
    • (2005) Neuron , vol.45 , pp. 11-16
    • Zhang, X.1    Gainetdinov, R.R.2    Beaulieu, J.-M.3
  • 69
    • 40849111647 scopus 로고    scopus 로고
    • A loss-of-function mutation in tryptophan hydroxylase 2 segregating with attention deficit/hyperactivity disorder
    • McKinney J, Johansson S, Halmoy A, et al. A loss-of-function mutation in tryptophan hydroxylase 2 segregating with attention deficit/hyperactivity disorder. Mol Psychiatry 2008;13:365-367
    • (2008) Mol Psychiatry , vol.13 , pp. 365-367
    • McKinney, J.1    Johansson, S.2    Halmoy, A.3
  • 70
    • 66749183401 scopus 로고    scopus 로고
    • Functional properties of missense variants of human tryptophan hydroxylase 2
    • McKinney JA, Turel B, Winge I, et al. Functional properties of missense variants of human tryptophan hydroxylase 2. Hum Mutat 2009;30:787-794
    • (2009) Hum Mutat , vol.30 , pp. 787-794
    • McKinney, J.A.1    Turel, B.2    Winge, I.3
  • 71
    • 19644401360 scopus 로고    scopus 로고
    • Support for the involvement of TPH2 gene in affective disorders
    • Harvey M, Shink E, Tremblay M, et al. Support for the involvement of TPH2 gene in affective disorders. Mol Psychiatry 2004;9:980-981
    • (2004) Mol Psychiatry , vol.9 , pp. 980-981
    • Harvey, M.1    Shink, E.2    Tremblay, M.3
  • 72
    • 5044238471 scopus 로고    scopus 로고
    • SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression
    • Zill P, Baghai TC, Zwanzger P, et al. SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression. Mol Psychiatry 2004;9:1030-1036
    • (2004) Mol Psychiatry , vol.9 , pp. 1030-1036
    • Zill, P.1    Baghai, T.C.2    Zwanzger, P.3
  • 73
    • 5044237402 scopus 로고    scopus 로고
    • Single nucleotide polymorphism and haplotype analysis of a novel tryptophan hydroxylase Isoform (TPH2) gene in suicide victims
    • DOI 10.1016/j.biopsych.2004.07.015, PII S0006322304008054
    • Zill P, Buttner A, Eisenmenger W, et al. Single nucleotype polymorphism and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene in suicide victims. Biol Psychiatry 2004;56:581-586 (Pubitemid 39336405)
    • (2004) Biological Psychiatry , vol.56 , Issue.8 , pp. 581-586
    • Zill, P.1    Buttner, A.2    Eisenmenger, W.3    Moller, H.-J.4    Bondy, B.5    Ackenheil, M.6
  • 74
    • 25844486999 scopus 로고    scopus 로고
    • Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations
    • Zhou Z, Roy A, Lipsky R, et al. Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations. Arch Gen Psychiatry 2005;62:1109-1118
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1109-1118
    • Zhou, Z.1    Roy, A.2    Lipsky, R.3
  • 75
    • 33750719946 scopus 로고    scopus 로고
    • Effect of SNP at position 40237 in exon 7 of the TPH2 gene on susceptibility to suicide
    • Ke L, Qi ZY, Ping Y, Ren CY. Effect of SNP at position 40237 in exon 7 of the TPH2 gene on susceptibility to suicide. Brain Res 2006;1122:24-26
    • (2006) Brain Res , vol.1122 , pp. 24-26
    • Ke, L.1    Qi, Z.Y.2    Ping, Y.3    Ren, C.Y.4
  • 76
    • 33846216741 scopus 로고    scopus 로고
    • Nested association between genetic variation in tryptophan hydroxylase II, bipolar affective disorder, and suicide attempts
    • Lopez VA, Detera-Wadleigh S, Cardona I, et al. Nested association between genetic variation in tryptophan hydroxylase II, bipolar affective disorder, and suicide attempts. Biol Psychiatry 2007;61:181-186
    • (2007) Biol Psychiatry , vol.61 , pp. 181-186
    • Lopez, V.A.1    Detera-Wadleigh, S.2    Cardona, I.3
  • 77
    • 34250214584 scopus 로고    scopus 로고
    • Effect of tryptophan hydroxylase 2 gene variants on suicide risk in major depression
    • Lopez de Lara C, Brezo J, Rouleau G, et al. Effect of tryptophan hydroxylase 2 gene variants on suicide risk in major depression. Biol Psychiatry 2007;62:72-80
    • (2007) Biol Psychiatry , vol.62 , pp. 72-80
    • Lopez De Lara, C.1    Brezo, J.2    Rouleau, G.3
  • 78
    • 47749122184 scopus 로고    scopus 로고
    • Genetic architecture of the human tryptophan hydroxilase 2 gene: Existence of neural isoforms and relevance for major depression
    • Haghighi F, Bach-Mizrachi H, Huang YY, et al. Genetic architecture of the human tryptophan hydroxilase 2 gene: existence of neural isoforms and relevance for major depression. Mol Psychiatry 2008;13:813-820
    • (2008) Mol Psychiatry , vol.13 , pp. 813-820
    • Haghighi, F.1    Bach-Mizrachi, H.2    Huang, Y.Y.3
  • 79
    • 37549044251 scopus 로고    scopus 로고
    • Brain-specific tryptophan hydroxylase 2 (TPH2): A functional Pro206Ser substitution and variation in the 5¢-region are associated with bipolar affective disorder
    • Cichon S, Winge I, Mattheisen M, et al. Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5¢-region are associated with bipolar affective disorder Hum Mol Genet 2008;17:87-97
    • (2008) Hum Mol Genet , vol.17 , pp. 87-97
    • Cichon, S.1    Winge, I.2    Mattheisen, M.3
  • 80
    • 27144536263 scopus 로고    scopus 로고
    • Amigdata responsiveness is modulated by tryptophan hydroxylase-2 gene variation
    • Canli T, Congdon E, Gutknecht L, et al. Amigdata responsiveness is modulated by tryptophan hydroxylase-2 gene variation. J Neural Transm 2005;112:1479-1485
    • (2005) J Neural Transm , vol.112 , pp. 1479-1485
    • Canli, T.1    Congdon, E.2    Gutknecht, L.3
  • 81
    • 46649117930 scopus 로고    scopus 로고
    • Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on neutral correlates of affective processing
    • Canli T, Congdon E, Constable RT, Lesch KP. Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on neutral correlates of affective processing. Biol Psychiatry 2008;79:118-125
    • (2008) Biol Psychiatry , vol.79 , pp. 118-125
    • Canli, T.1    Congdon, E.2    Constable, R.T.3    Lesch, K.P.4
  • 82
    • 34247111741 scopus 로고    scopus 로고
    • Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on emotional processing
    • Herrmann MJ, Huter T, Muller, et al. Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on emotional processing. Cereb Cortex 2007;17:1160-1163
    • (2007) Cereb Cortex , vol.17 , pp. 1160-1163
    • Herrmann, M.J.1    Muller, H.T.2
  • 83
    • 33847791414 scopus 로고    scopus 로고
    • Impaired executive control is associated with a variation in the promoter region of the tryptophan hydroxylase 2 gene
    • Reuter M, Ott U, Vaitl D, Hennig J. Impaired executive control is associated with a variation in the promoter region of the tryptophan hydroxylase 2 gene. J Cogn Neurosci 2007;19:401-408
    • (2007) J Cogn Neurosci , vol.19 , pp. 401-408
    • Reuter, M.1    Ott, U.2    Vaitl, D.3    Hennig, J.4
  • 84
    • 27144538430 scopus 로고    scopus 로고
    • Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in attention-deficit/ hyperactivity disorder
    • Walitza S, Renner TJ, Dempfle A, et al. Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in attention-deficit/ hyperactivity disorder. Mol Psychiatry 2005;10:1126-1132
    • (2005) Mol Psychiatry , vol.10 , pp. 1126-1132
    • Walitza, S.1    Renner, T.J.2    Dempfle, A.3
  • 85
    • 55049119444 scopus 로고    scopus 로고
    • Investigation of the tryptophan hydroxylase-2 gene in bipolar i disorder in the Romanian population
    • Grigoroiu-Serbanescu M, Diaconu CC, Herms S, et al. Investigation of the tryptophan hydroxylase-2 gene in bipolar I disorder in the Romanian population. Psychiatr Genet 2008;18:240-247
    • (2008) Psychiatr Genet , vol.18 , pp. 240-247
    • Grigoroiu-Serbanescu, M.1    Diaconu, C.C.2    Herms, S.3
  • 87
    • 60049090576 scopus 로고    scopus 로고
    • A tryptophan hydroxylase 2 gene polymorphism is associated with panic disorder
    • Kim Y-K, Lee H-J, Yang JC, et al. A tryptophan hydroxylase 2 gene polymorphism is associated with panic disorder. Behav Genet 2009;39:170-175
    • (2009) Behav Genet , vol.39 , pp. 170-175
    • Kim, Y.-K.1    Lee, H.-J.2    Yang, J.C.3
  • 88
    • 33745056057 scopus 로고    scopus 로고
    • The novel brain-specific tryptophan hydroxylase-2 gene in panic disorder
    • Mossner R, Freitag CM, Gutknecht L, et al. The novel brain-specific tryptophan hydroxylase-2 gene in panic disorder. J Psychopharmacol 2006;20:547-552
    • (2006) J Psychopharmacol , vol.20 , pp. 547-552
    • Mossner, R.1    Freitag, C.M.2    Gutknecht, L.3
  • 89
    • 33745698333 scopus 로고    scopus 로고
    • No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjects
    • Delorme R, Durand CM, Betancur C, et al. No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjects. Biol Psychiatry 2006;60:202-203
    • (2006) Biol Psychiatry , vol.60 , pp. 202-203
    • Delorme, R.1    Durand, C.M.2    Betancur, C.3
  • 90
    • 27544495122 scopus 로고    scopus 로고
    • Lack of association of TPH2 exon XI polymorphisms with major depression and treatment resistance
    • Garriock HA, Allen JJ, Delgado P, et al. Lack of association of TPH2 exon XI polymorphisms with major depression and treatment resistance. Mol Psychiatry 2005;10:976-977
    • (2005) Mol Psychiatry , vol.10 , pp. 976-977
    • Garriock, H.A.1    Allen, J.J.2    Delgado, P.3
  • 91
    • 33644811359 scopus 로고    scopus 로고
    • Response to Zhang et al (2005): Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16
    • Glatt CE, Carlson E, Taylor TR, et al. Response to Zhang, et al (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16. Neuron 2005;48:704-705
    • (2005) Neuron , vol.48 , pp. 704-705
    • Glatt, C.E.1    Carlson, E.2    Taylor, T.R.3
  • 92
    • 34548699892 scopus 로고    scopus 로고
    • Absence of the Arg441His polymorphism in the tryptophan hydroxylase 2 gene in adults with anxiety disorders and depression
    • Henningsson S, Annerbrink K, Olsson M, et al. Absence of the Arg441His polymorphism in the tryptophan hydroxylase 2 gene in adults with anxiety disorders and depression. Am J Med Genet (Neuropsychiatric Genetics) 2007;177:816-817
    • (2007) Am J Med Genet (Neuropsychiatric Genetics) , vol.177 , pp. 816-817
    • Henningsson, S.1    Annerbrink, K.2    Olsson, M.3
  • 93
    • 33644811359 scopus 로고    scopus 로고
    • Response to Zhang et al (2005): Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16
    • Van Den Bogaert A, De Zutter S, Heyrman L, et al. Response to Zhang, et al (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16. Neuron 2005;48:704
    • (2005) Neuron , vol.48 , pp. 704
    • Van Den Bogaert, A.1    De Zutter, S.2    Heyrman, L.3
  • 94
    • 24744463656 scopus 로고    scopus 로고
    • Genotype-dependent activity of tryptophan hydroxylase-2 determines the response to citalopram in a mouse model of depression
    • Cervo L, Canetta A, Calcagno E, et al. Genotype-dependent activity of tryptophan hydroxylase-2 determines the response to citalopram in a mouse model of depression. J Neurosci 2005;25:8165-8172
    • (2005) J Neurosci , vol.25 , pp. 8165-8172
    • Cervo, L.1    Canetta, A.2    Calcagno, E.3
  • 95
    • 35248874282 scopus 로고    scopus 로고
    • Strain differences in basal and post-citalopram extracellular 5-HT in the mouse medial prefrontal cortex and dorsal hippocampus: Relation with tryptophan hydroxylase-2 activity
    • Calcagno E, Canetta A, Guzzetti S, et al. Strain differences in basal and post-citalopram extracellular 5-HT in the mouse medial prefrontal cortex and dorsal hippocampus: relation with tryptophan hydroxylase-2 activity. J Neurochem 2007;103:1111-1120
    • (2007) J Neurochem , vol.103 , pp. 1111-1120
    • Calcagno, E.1    Canetta, A.2    Guzzetti, S.3
  • 96
    • 44449124504 scopus 로고    scopus 로고
    • Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment
    • Tzvetkov MV, Brockmoller J, Roots I, Kirchheiner J. Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment. Pharmacogenet Genomics 2008;18:495-506
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 495-506
    • Tzvetkov, M.V.1    Brockmoller, J.2    Roots, I.3    Kirchheiner, J.4
  • 97
    • 4644303054 scopus 로고    scopus 로고
    • Investigation of serotonin-related genes in antidepressant response
    • Peters EJ, Slager SL, McGrath PJ, et al. Investigation of serotonin-related genes in antidepressant response. Mol Psychiatry 2004;9:879-889
    • (2004) Mol Psychiatry , vol.9 , pp. 879-889
    • Peters, E.J.1    Slager, S.L.2    McGrath, P.J.3
  • 98
    • 58149216282 scopus 로고    scopus 로고
    • Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response
    • Peters EJ, Slager SL, Jenkins GD. Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response. Pharmacogenet Genomics 2009;19:1-10
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 1-10
    • Peters, E.J.1    Slager, S.L.2    Jenkins, G.D.3
  • 99
    • 67349252484 scopus 로고    scopus 로고
    • Tryptophan hydroxylase 2 gene is associated with major depression and antidepressant treatment response
    • Tsai SJ, Hong CJ, Liou YJ, et al. Tryptophan hydroxylase 2 gene is associated with major depression and antidepressant treatment response. Prog Neuropsychopharmacol Biol Psychiatry 2009;33:637-641
    • (2009) Prog Neuropsychopharmacol Biol Psychiatry , vol.33 , pp. 637-641
    • Tsai, S.J.1    Hong, C.J.2    Liou, Y.J.3
  • 100
    • 0027689454 scopus 로고
    • The use of diet and dietary components in the study of factors controlling affect in humans: A review
    • Young SN. The use of diet and dietary components in the study of factors controlling affect in humans: a review. J Psychiatr Neurosci 1993;18:235-244
    • (1993) J Psychiatr Neurosci , vol.18 , pp. 235-244
    • Young, S.N.1
  • 101
    • 0026738624 scopus 로고
    • Acute tryptophan depletion: A method of studying antidepressant action
    • Miller Miller HL, Delgado PL, Salomon RM, et al. Acute tryptophan depletion: a method of studying antidepressant action. J Clin Psychiatry 1992;53(Suppl):28-35
    • (1992) J Clin Psychiatry , vol.53 , Issue.SUPPL. , pp. 28-35
    • Miller Miller, H.L.1    Delgado, P.L.2    Salomon, R.M.3
  • 103
    • 0030296721 scopus 로고    scopus 로고
    • Mood responses to acute tryptophan depletion in healthy volunteers: Sex differences and temporal stability
    • Ellenbogen MA, Young SN, Dean P, et al. Mood responses to acute tryptophan depletion in healthy volunteers: sex differences and temporal stability. Neuropsychopharmacol 1996;15:465-474
    • (1996) Neuropsychopharmacol , vol.15 , pp. 465-474
    • Ellenbogen, M.A.1    Young, S.N.2    Dean, P.3
  • 104
    • 0030975670 scopus 로고    scopus 로고
    • The effect of tryptophan depletion on mood in medication-free, former patients with major affective disorder
    • Leyton M, Young SN, Blier P, et al. The effect of tryptophan depletion on mood in medication-free, former patients with major affective disorder. Neuropsychopharmacol 1997;16:294-297
    • (1997) Neuropsychopharmacol , vol.16 , pp. 294-297
    • Leyton, M.1    Young, S.N.2    Blier, P.3
  • 105
    • 0032774799 scopus 로고    scopus 로고
    • Mood effects of 24-hour tryptophan depletion in healthy first-degree relatives of patients with affective disorders
    • Klaassen T, Riedel WJ, van Someren A, et al. Mood effects of 24-hour tryptophan depletion in healthy first-degree relatives of patients with affective disorders. Biol Psychiatry 1999;46:489-497
    • (1999) Biol Psychiatry , vol.46 , pp. 489-497
    • Klaassen, T.1    Riedel, W.J.2    Van Someren, A.3
  • 106
    • 3543136066 scopus 로고    scopus 로고
    • Neural and behavioral responses to tryptophan depletion in unmedicated patients with remitted major depressive disorder and controls
    • Neumeister A, Nugent AC, Waldeck T, et al. Neural and behavioral responses to tryptophan depletion in unmedicated patients with remitted major depressive disorder and controls. Arch Gen Psychiatry 2004;61:765-773
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 765-773
    • Neumeister, A.1    Nugent, A.C.2    Waldeck, T.3
  • 107
    • 0030802876 scopus 로고    scopus 로고
    • Rapid tryptophan depletion in drug-free depressed patients with seasonal affective disorder
    • Neumeister A, Praschak-Rieder N, Hesselmann B, et al. Rapid tryptophan depletion in drug-free depressed patients with seasonal affective disorder. Am J Psychiatry 1997;154:1153-1155
    • (1997) Am J Psychiatry , vol.154 , pp. 1153-1155
    • Neumeister, A.1    Praschak-Rieder, N.2    Hesselmann, B.3
  • 108
    • 2642607850 scopus 로고    scopus 로고
    • Rapid tryptophan depletion, sleep electroencephalogram, and mood in men with remitted depression on serotonin reuptake inhibitors
    • Moore P, Gillin JC, Bhatti T, et al. Rapid tryptophan depletion, sleep electroencephalogram, and mood in men with remitted depression on serotonin reuptake inhibitors. Arch Gen Psychiatry 1998;55:534-539
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 534-539
    • Moore, P.1    Gillin, J.C.2    Bhatti, T.3
  • 109
    • 0025318311 scopus 로고
    • Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan
    • Delgado PL, Charney DS, Price LH, et al. Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. Arch Gen Psychiatry 1990;47:411-418
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 411-418
    • Delgado, P.L.1    Charney, D.S.2    Price, L.H.3
  • 110
    • 0030611068 scopus 로고    scopus 로고
    • Relapse of depression after rapid depletion of tryptophan
    • Smith KA, Fairburn CG, Cowen PJ. Relapse of depression after rapid depletion of tryptophan. Lancet 1997;349:915-919
    • (1997) Lancet , vol.349 , pp. 915-919
    • Smith, K.A.1    Fairburn, C.G.2    Cowen, P.J.3
  • 111
  • 112
    • 0035054352 scopus 로고    scopus 로고
    • The effect of tryptophan depletion on mood and psychiatric symptoms
    • Van der Does AJW. The effect of tryptophan depletion on mood and psychiatric symptoms. J Affect Disord 2001;64:107-119
    • (2001) J Affect Disord , vol.64 , pp. 107-119
    • Van Der Does, A.J.W.1
  • 113
    • 0035021701 scopus 로고    scopus 로고
    • Tryptophan depletion and its implications for psychiatry
    • Bell C, Abrams J, Nutt D. Tryptophan depletion and its implications for psychiatry. Br J Psychiatry 2001;178:399-405
    • (2001) Br J Psychiatry , vol.178 , pp. 399-405
    • Bell, C.1    Abrams, J.2    Nutt, D.3
  • 114
    • 0030944433 scopus 로고    scopus 로고
    • Positron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse
    • Bremner JD, Innis RB, Salomon RM, et al. Positron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse. Arch Gen Psychiatry 1997;54:364-374
    • (1997) Arch Gen Psychiatry , vol.54 , pp. 364-374
    • Bremner, J.D.1    Innis, R.B.2    Salomon, R.M.3
  • 115
    • 0031920874 scopus 로고    scopus 로고
    • Serotonergic 'vulnerability' in affective disorder: A study of the tryptophan depletion test and relationships between peripheral and central serotonin indexes in citalopram-responders
    • Aberg-Wistedt A, Hasselmark L, Stain-Malmgren R, et al. Serotonergic 'vulnerability' in affective disorder: a study of the tryptophan depletion test and relationships between peripheral and central serotonin indexes in citalopram-responders. Acta Psychiatr Scand 1998;97:374-380 (Pubitemid 28191915)
    • (1998) Acta Psychiatrica Scandinavica , vol.97 , Issue.5 , pp. 374-380
    • Aberg-Wistedt, A.1    Hasselmark, L.2    Stain-Malmgren, R.3    Aperia, B.4    Kjellman, B.F.5    Mathe, A.A.6
  • 116
    • 0025757280 scopus 로고
    • Role of serotonin in therapy of depression and related disorders
    • Fuller RW. Role of serotonin in therapy of depression and related disorders. J Clin Psychiatry 1991;52:52-57
    • (1991) J Clin Psychiatry , vol.52 , pp. 52-57
    • Fuller, R.W.1
  • 117
    • 0342269017 scopus 로고
    • Nutritional control of central neurotransmitters
    • Pirk KM, Ploog D, editors, Springer-Verlag, Berlin
    • Wurtman RJ, Wurtman JJ. Nutritional control of central neurotransmitters. In: Pirk KM, Ploog D, editors, The psychobiology of anorexia nervosa. Springer-Verlag, Berlin; 1984. p. 4-12
    • (1984) The Psychobiology of Anorexia Nervosa , pp. 4-12
    • Wurtman, R.J.1    Wurtman, J.J.2
  • 118
    • 0025012242 scopus 로고
    • Aromatic amino acids and monoamine synthesis in the central nervous system: Influence of the diet
    • Fernstrom JD. Aromatic amino acids and monoamine synthesis in the central nervous system: influence of the diet. J Nutr Biochem 1990;1:508-517
    • (1990) J Nutr Biochem , vol.1 , pp. 508-517
    • Fernstrom, J.D.1
  • 119
    • 0018875090 scopus 로고
    • Relationship between plasma ratio of tryptophan to competing amino acids and the response to L-tryptophan treatment in endogenously depressed patients
    • Moller SE, Kirk L, Honore P. Relationship between plasma ratio of tryptophan to competing amino acids and the response to L-tryptophan treatment in endogenously depressed patients. J Affect Disord 1980;2:47-59
    • (1980) J Affect Disord , vol.2 , pp. 47-59
    • Moller, S.E.1    Kirk, L.2    Honore, P.3
  • 120
    • 0030920083 scopus 로고    scopus 로고
    • L-Tryptophan augmentation of light therapy in patients with seasonal affective disorder
    • Lam RW, Levitan RD, Tam EM, et al. L-Tryptophan augmentation of light therapy in patients with seasonal affective disorder. Can J Psychiatry 1997;42:303-306
    • (1997) Can J Psychiatry , vol.42 , pp. 303-306
    • Lam, R.W.1    Levitan, R.D.2    Tam, E.M.3
  • 121
    • 0022907565 scopus 로고
    • Remarks on the therapy of depression with amine precursors
    • Hippius H, Matussek N. Remarks on the therapy of depression with amine precursors. Psychopathology 1986;19:132-135
    • (1986) Psychopathology , vol.19 , pp. 132-135
    • Hippius, H.1    Matussek, N.2
  • 122
    • 0017085994 scopus 로고
    • Potentiation of antidepressant action of clomipramine by tryptophan
    • Walinder J, Skott A, Carlsson A, et al. Potentiation of antidepressant action of clomipramine by tryptophan. Arch Gen Psychiatry 1976;33:1384-1389
    • (1976) Arch Gen Psychiatry , vol.33 , pp. 1384-1389
    • Walinder, J.1    Skott, A.2    Carlsson, A.3
  • 123
    • 0026950322 scopus 로고
    • L-Tryptophan in neuropsychiatric disorders: A review
    • Sandyk R. L-Tryptophan in neuropsychiatric disorders: a review. Int J Neurosci 1992;67:127-144
    • (1992) Int J Neurosci , vol.67 , pp. 127-144
    • Sandyk, R.1
  • 124
    • 0032878861 scopus 로고    scopus 로고
    • Dietary supplements and natural products as psychotherapeutic agents
    • Fugh-Berman A, Cott JM. Dietary supplements and natural products as psychotherapeutic agents. Psychosomat Med 1999;61:712-728
    • (1999) Psychosomat Med , vol.61 , pp. 712-728
    • Fugh-Berman, A.1    Cott, J.M.2
  • 125
    • 77958048852 scopus 로고
    • Precursor loading strategies
    • Barchas J, Usdin E, editors, Academic Press, New York
    • Carroll BJ. Precursor loading strategies. In: Barchas J, Usdin E, editors, Serotonin and behavior. Academic Press, New York; 1973. p. 481-482
    • (1973) Serotonin and Behavior , pp. 481-482
    • Carroll, B.J.1
  • 127
    • 0019508895 scopus 로고
    • Management of depression with serotonin precursor
    • Van Praag HM. Management of depression with serotonin precursor. Biol Psychiatry 1981;16:291-310
    • (1981) Biol Psychiatry , vol.16 , pp. 291-310
    • Van Praag, H.M.1
  • 128
    • 0022995996 scopus 로고
    • The pitfalls of serotonin precursors as chellengers in hormonal probes of central serotonin activity
    • Van Pragg HM, Lemus C, Kahn R. The pitfalls of serotonin precursors as chellengers in hormonal probes of central serotonin activity. Psychopharmacol Bull 1986;22:565-570
    • (1986) Psychopharmacol Bull , vol.22 , pp. 565-570
    • Van Pragg, H.M.1    Lemus, C.2    Kahn, R.3
  • 129
    • 0029745560 scopus 로고    scopus 로고
    • Alpha-Lactalbumin enriched low-protein infant formulas: A comparison to breast milk feeding
    • Heine W, Radke M, Wutzke KD, et al. alpha-Lactalbumin enriched low-protein infant formulas: a comparison to breast milk feeding. Acta Paediatr 1996;85:1024-1028
    • (1996) Acta Paediatr , vol.85 , pp. 1024-1028
    • Heine, W.1    Radke, M.2    Wutzke, K.D.3
  • 130
    • 0034085615 scopus 로고    scopus 로고
    • The bovine protein alpha-lactalbumin increases the plasma Trp/LNAA, and in vulnerable subjects it raises brain serotonin activity, reduces cortisol and improves mood under stress
    • Markus CR, Olivier B, Panhuysen G, et al. The bovine protein alpha-lactalbumin increases the plasma Trp/LNAA, and in vulnerable subjects it raises brain serotonin activity, reduces cortisol and improves mood under stress. Am J Clin Nutr 2000;71:1536-1544
    • (2000) Am J Clin Nutr , vol.71 , pp. 1536-1544
    • Markus, C.R.1    Olivier, B.2    Panhuysen, G.3
  • 131
    • 20544471693 scopus 로고    scopus 로고
    • Evening intake of alpha-lactalbumin increases plasma tryptophan availability and improves morning alertness and brain measures of attention
    • Markus CR, Jonkman LM, Lammers J, et al. Evening intake of alpha-lactalbumin increases plasma tryptophan availability and improves morning alertness and brain measures of attention. Am J Clin Nutr 2005;81:1026-1033
    • (2005) Am J Clin Nutr , vol.81 , pp. 1026-1033
    • Markus, C.R.1    Jonkman, L.M.2    Lammers, J.3
  • 132
    • 0347626245 scopus 로고    scopus 로고
    • Alpha-lactalbumin-enriched diets enhance serotonin release and induce anxiolytic and rewarding effects in the rat
    • Orosco M, Rouch C, Beslot F, et al. Alpha-lactalbumin-enriched diets enhance serotonin release and induce anxiolytic and rewarding effects in the rat. Behav Brain Res 2004;148:1-10
    • (2004) Behav Brain Res , vol.148 , pp. 1-10
    • Orosco, M.1    Rouch, C.2    Beslot, F.3
  • 133
    • 34547136705 scopus 로고    scopus 로고
    • Effects of alpha-lactalbumin on emotional processing in healthy women
    • Scrutton H, Carbonnier A, Cowen PJ, Harmer CJ. Effects of alpha-lactalbumin on emotional processing in healthy women. J Psychopharmacol 2007;21:519-524
    • (2007) J Psychopharmacol , vol.21 , pp. 519-524
    • Scrutton, H.1    Carbonnier, A.2    Cowen, P.J.3    Harmer, C.J.4
  • 134
    • 26044472785 scopus 로고    scopus 로고
    • The effects of a diet enriched with alpha-lactalbumin on mood and cortisol response in unmedicated recovered depressed subjects and controls
    • Merens W, Booij L, Markus CR, et al. The effects of a diet enriched with alpha-lactalbumin on mood and cortisol response in unmedicated recovered depressed subjects and controls. Br J Nutr 2005;94:415-422
    • (2005) Br J Nutr , vol.94 , pp. 415-422
    • Merens, W.1    Booij, L.2    Markus, C.R.3
  • 135
    • 0015817948 scopus 로고
    • Correlations between brain tryptophan and plasma neutral amino acids levels following food consumption in rats
    • Fernstrom JD, Larin F, Wartman RJ. Correlations between brain tryptophan and plasma neutral amino acids levels following food consumption in rats. Life Sci 1973;13:517-524
    • (1973) Life Sci , vol.13 , pp. 517-524
    • Fernstrom, J.D.1    Larin, F.2    Wartman, R.J.3
  • 136
    • 0002324880 scopus 로고
    • Effects of food intake on brain transmitter amine precursors and amine synthesis
    • Sandler M, Silverstone T, editors, Oxford University Press, Oxford
    • Curzon G. Effects of food intake on brain transmitter amine precursors and amine synthesis. In: Sandler M, Silverstone T, editors, Psychopharmacology and food. Oxford University Press, Oxford; 1985. p. 59-70
    • (1985) Psychopharmacology and Food , pp. 59-70
    • Curzon, G.1
  • 137
    • 0023641525 scopus 로고
    • Nutrients affecting brain composition and behavior
    • Wurtmam RJ. Nutrients affecting brain composition and behavior. Integr Psychiatry 1987;5:226-257
    • (1987) Integr Psychiatry , vol.5 , pp. 226-257
    • Wurtmam, R.J.1
  • 138
    • 0022495372 scopus 로고
    • Carbohydrate craving, obesity and brain serotonin
    • Wurtman RJ, Wurtman JJ. Carbohydrate craving, obesity and brain serotonin. Appetite 1986;7:99-103
    • (1986) Appetite , vol.7 , pp. 99-103
    • Wurtman, R.J.1    Wurtman, J.J.2
  • 139
    • 0023038465 scopus 로고
    • Changes in mood after carbohydrate consumption among obese individuals
    • Lieberman HR, Wurtman JJ, Chew B. Changes in mood after carbohydrate consumption among obese individuals. Am J Clin Nutr 1986;44:772-778
    • (1986) Am J Clin Nutr , vol.44 , pp. 772-778
    • Lieberman, H.R.1    Wurtman, J.J.2    Chew, B.3
  • 140
    • 0024360884 scopus 로고
    • Psychobiological effects carbohydrate- and protein rich meals in patients with seasonal affective disorder and normal controls
    • Rosenthal NE, Genhart MJ Caballero B, et al. Psychobiological effects carbohydrate- and protein rich meals in patients with seasonal affective disorder and normal controls. Biol Psychiatry 1989;25:1029-1040
    • (1989) Biol Psychiatry , vol.25 , pp. 1029-1040
    • Rosenthal, N.E.1    Genhart, M.2    Caballero, B.3
  • 142
    • 0028349014 scopus 로고
    • Tryptophan in the treatment of late luteal phase dysphoric disorder: A pilot study
    • Steinberg S, Annable L, Young SN. Tryptophan in the treatment of late luteal phase dysphoric disorder: a pilot study. J Psychiatry Neurosci 1994;19:114-119
    • (1994) J Psychiatry Neurosci , vol.19 , pp. 114-119
    • Steinberg, S.1    Annable, L.2    Young, S.N.3
  • 143
    • 0029075831 scopus 로고
    • The effect of carbohydrate-rich beverage on mood, appetite, and cognitive function in women with premenstrual syndrome
    • Sayegh R, Schiff I, Wurtman J, et al. The effect of carbohydrate-rich beverage on mood, appetite, and cognitive function in women with premenstrual syndrome. Obstet Gynecol 1995;86:520-528
    • (1995) Obstet Gynecol , vol.86 , pp. 520-528
    • Sayegh, R.1    Schiff, I.2    Wurtman, J.3
  • 144
    • 77950826102 scopus 로고    scopus 로고
    • TPH2 5¢- and 3¢-regulatory polymorphisms are differently associated with HPA axis function and self-injurious behavior in rhesus monkeys
    • Chen GL, Novak MA, Meyer JS, et al. TPH2 5¢- and 3¢-regulatory polymorphisms are differently associated with HPA axis function and self-injurious behavior in rhesus monkeys. Genes Brain Behav 2010;9:335-347
    • (2010) Genes Brain Behav , vol.9 , pp. 335-347
    • Chen, G.L.1    Novak, M.A.2    Meyer, J.S.3
  • 145
    • 77953806857 scopus 로고    scopus 로고
    • Receptor-genes cross-talk: Effect of chronic 5-HT1A agonist 8-hydroxy-2-(di-N-propylamino) tetralin treatment on the expression of key genes in brain serotonin system and on behavior
    • Popova NK, Naumenko VS, Cybko AS, Bazovkina DV. Receptor-genes cross-talk: effect of chronic 5-HT1A agonist 8-hydroxy-2-(di-N-propylamino) tetralin treatment on the expression of key genes in brain serotonin system and on behavior. Neurosci 2010;169:229-235
    • (2010) Neurosci , vol.169 , pp. 229-235
    • Popova, N.K.1    Naumenko, V.S.2    Cybko, A.S.3    Bazovkina, D.V.4
  • 146
    • 0037242342 scopus 로고    scopus 로고
    • Phenylketonuria: Genotype-phenotype correlations based on expression analysis of structural and functional mutations in PAH
    • Pey AL, Desviat LR, Gamez A, et al. Phenylketonuria: genotype-phenotype correlations based on expression analysis of structural and functional mutations in PAH. Hum Mutat 2003;21:370-378
    • (2003) Hum Mutat , vol.21 , pp. 370-378
    • Pey, A.L.1    Desviat, L.R.2    Gamez, A.3
  • 147
    • 0037240146 scopus 로고    scopus 로고
    • How PAH gene mutations cause hyperphenylalaninemia and why mechanism matters: Insights from in vitro expression
    • Waters PJ. How PAH gene mutations cause hyperphenylalaninemia and why mechanism matters: insights from in vitro expression. Hum Mutat 2003;21:357-369
    • (2003) Hum Mutat , vol.21 , pp. 357-369
    • Waters, P.J.1
  • 148
    • 77749245886 scopus 로고    scopus 로고
    • Alternative splicing and extensive RNA editing of human TPH2 transcripts
    • Grohmann M, Hammer P, Walther M, et al. Alternative splicing and extensive RNA editing of human TPH2 transcripts. PLos ONE 2010;5:e8956
    • (2010) PLos ONE , vol.5
    • Grohmann, M.1    Hammer, P.2    Walther, M.3
  • 149
    • 75549091083 scopus 로고    scopus 로고
    • Tryptophan hydroxylase as novel target for the treatment of depressive disorders
    • Matthes S, Mosienko V, Bashammakh S, et al. Tryptophan hydroxylase as novel target for the treatment of depressive disorders. Pharmacology 2010;85:95-109
    • (2010) Pharmacology , vol.85 , pp. 95-109
    • Matthes, S.1    Mosienko, V.2    Bashammakh, S.3


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