Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice

Journal of Neural Transmission

Volumn 115, Issue 8, 2008, Pages 1127-1132

  Gutknecht, Lise ^a   Waider, Jonas ^a   Kraft, Stefanie ^a   Kriegebaum, Claudia ^a   Holtmann, Bettina ^b   Reif, Andreas ^a   Schmitt, Angelika ^a   Lesch, Klaus Peter ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Attention deficit hyperactivity disorder; Depression; Development; Knockout; Serotonin; Tph2; Tryptophan hydroxylase 2

Indexed keywords

SEROTONIN; TRYPTOPHAN HYDROXYLASE; TRYPTOPHAN HYDROXYLASE 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL STRUCTURE; COGNITION; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; EMOTION; ENZYME DEFICIENCY; ENZYME SPECIFICITY; GENE DISRUPTION; GENE TARGETING; HOMOLOGOUS RECOMBINATION; KNOCKOUT GENE; MOLECULAR CLONING; MOUSE; NERVE CELL; NERVE FIBER; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; SEROTONIN BRAIN LEVEL; SEROTONIN METABOLISM; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM; TISSUE DISTRIBUTION; TPH2 GENE;

ANIMALS; BRAIN; BRAIN CHEMISTRY; GENE DELETION; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; RAPHE NUCLEI; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TRYPTOPHAN HYDROXYLASE;

EID: 49749117799     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-008-0096-6     Document Type: Article

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