Functional characterization of the human TPH2 5′ regulatory region: Untranslated region and polymorphisms modulate gene expression in vitro

Human Genetics

Volumn 122, Issue 6, 2008, Pages 645-657

  Chen, Guo Lin ^a   Vallender, Eric J ^a   Miller, Gregory M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CIS ACTING ELEMENT; DNA; GUANINE; LUCIFERASE; SEROTONIN; TRYPTOPHAN HYDROXYLASE 2; TYROSINE;

5' UNTRANSLATED REGION; ALLELE; ARTICLE; BEHAVIOR DISORDER; CELL STRAIN HEK293; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME ASSAY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENE LOCUS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC REGULATION; GENETIC TRANSCRIPTION; HAPLOTYPE; HUMAN; HUMAN CELL; IN VITRO STUDY; MENTAL DISEASE; NERVE CELL; NUCLEOTIDE SEQUENCE; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN RNA BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION;

5' FLANKING REGION; 5' UNTRANSLATED REGIONS; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); RATS; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRYPTOPHAN HYDROXYLASE;

EID: 37749008643     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-007-0443-y     Document Type: Article

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