The effect of tryptophan depletion on mood in medication-free, former patients with major affective disorder

Neuropsychopharmacology

Volumn 16, Issue 4, 1997, Pages 294-297

  Leyton, Marco ^a   Young, Simon N ^a   Blier, Pierre ^a   Ellenbogen, Mark A ^a   Palmour, Roberta M ^a   Ghadirian, A Missagh ^a   Benkelfat, Chawki ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Depression; Relapse; Serotonin; Tryptophan depletion

Indexed keywords

ANTIDEPRESSANT AGENT; TRYPTOPHAN;

ARTICLE; HUMAN; MANIC DEPRESSIVE PSYCHOSIS; MOOD; PRIORITY JOURNAL;

ADULT; AFFECT; DIET; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; MOOD DISORDERS; PSYCHIATRIC STATUS RATING SCALES; TRYPTOPHAN;

EID: 0030975670     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(96)00262-X     Document Type: Article

References (13)

1. Beigel A, Murphy DL, Bunney WE (1971): The Manic-State Rating Scale: Scale construction, reliability, and validity. Arch Gen Psychiatr 25:256-262
2. Benkelfat C, Ellenbogen MA, Dean P, Palmour RM, Young SN (1994): Mood-lowering effect of tryptophan depletion: Enhanced susceptibility in young men at genetic risk for major affective disorders. Arch Gen Psychiatr 51:687-697
3. Bond A, Lader M (1974): The use of analogue scales in rating subjective feelings. Br J Med Psychol 47:211-218
4. Delgado PL, Charney DS, Price LH, Aghajanian GK, Landis H, Heninger GR (1990): Serotonin function and the mechanism of antidepressant action: Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. Arch Gen Psychiatr 47:411-418
5. Delgado PL, Miller HL, Salomon RS, Licinio J, Price LH, Heninger GR, Krystal JH, Charney DS (1991): Serotonin function and the mechanism of antidepressant action. Soc Neurosci Abstr 569.9
6. Ellenbogen MA, Young SN, Dean P, Palmour RM, Benkelfat C (1996): Mood responses to acute tryptophan depletion in healthy volunteers: Sex differences and temporal stability. Neuropsychopharmacology 15:465-474
7. Hamilton M (1960): Rating depressive patients. J Clin Psychiatr 41:21-24
8. McNair DM, Lorr M, Droppleman LF (1988): Manual for the Profile of Mood States. San Diego, CA, Educational and Industrial Testing Service
9. Miller HL, Damell A, Cappiello A, Benman R, Anand A, Charney DS (1996): Serotonin function and vulnerability to depression. Biol Psychiatr 39:528
10. Moreno F, Gelenberg AJ, Potter R, Delgado PL (1995): Tryptophan depletion and vulnerability to depression. Am Coll Neurosychopharmacol Abstr 34:121
11. Nishizawa S, Benkelfat C, Young SN, Leyton M, Mzengeza S, de Montigny C, Blier P, Diksic M (submitted): Differences between males and females in rates of serotonin synthesis in human brain
12. Nurnberger JI, Blehar MC, Kaufman CA, York-Cooler C, Simpson SG, Harkavy-Friedman J, Severe JB, Malaspina D, Reich T (1994): Diagnostic interview for genetic studies: Rationale, unique features, and training. Arch Gen Psychiatr 51:849-859
13. Spitzer RL (1987): Structured Clinical Interview for DSM-IIIR. New York, Biometrics Research Department, New York State Psychiatric Institute