High-affinity Na+-dependent dicarboxylate cotransporter promotes cellular senescence by inhibiting SIRT1

Mechanisms of Ageing and Development

Volumn 131, Issue 10, 2010, Pages 601-613

  Liu, Weiping ^a   Hong, Quan ^a   Bai, Xue Yuan ^a   Fu, Bo ^a   Xie, Yuansheng ^a   Zhang, Xueguang ^a   Li, Jianjun ^a   Shi, Suozhu ^a   Lv, Yang ^a   Sun, Xuefeng ^a   Chen, Xiangmei ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Cellular senescence; Energy metabolism; NAD+ NADH ratio; NaDC3; SIRT1

Indexed keywords

DICARBOXYLATE TRANSPORTER; HISTONE DEACETYLASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTEIN P16; PROTEIN P21; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SIRTUIN 1; SODIUM DEPENDENT DICARBOXYLATE COTRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL AGING; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL LINE; CITRIC ACID CYCLE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; KIDNEY; LUNG FIBROBLAST; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

ANIMALS; CELL AGING; CELL LINE; CITRIC ACID CYCLE; HUMANS; MALE; NAD; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; RATS; RATS, WISTAR; SIRTUIN 1;

MAMMALIA;

EID: 77957891361     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2010.08.006     Document Type: Article

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