메뉴 건너뛰기




Volumn , Issue , 2009, Pages 79-108

Adipose Tissue: Development, Anatomy and Functions

Author keywords

Adipocytes derived from mesenchymal stem cells; Adipose tissue development, anatomy and functions; Bone morphogenetic protein important in the development of brown adipocytes; Brown adipose tissue (BAT) adapted for heat production; Leptin protein expressed by white adipocytes; Lipogenesis; Lipolysis; Pericytes cells that surround the endothelium tubes of the microvasculature; White adipose tissue loose connective tissue

Indexed keywords


EID: 77957705175     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470712221.ch4     Document Type: Chapter
Times cited : (8)

References (159)
  • 2
    • 1442326009 scopus 로고    scopus 로고
    • Discrimination between obesity and insulin resistance in the relationship with adiponectin
    • Abbasi, F., Chu, J.W., Lamendola, C. et al. (2004) Discrimination between obesity and insulin resistance in the relationship with adiponectin. Diabetes, 53, 585-90.
    • (2004) Diabetes , vol.53 , pp. 585-590
    • Abbasi, F.1    Chu, J.W.2    Lamendola, C.3
  • 3
    • 0037129861 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell
    • Arita, Y., Kihara, S., Ouchi, N. et al. (2002) Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell. Circulation, 105, 2893-8.
    • (2002) Circulation , vol.105 , pp. 2893-2898
    • Arita, Y.1    Kihara, S.2    Ouchi, N.3
  • 4
    • 33747061905 scopus 로고    scopus 로고
    • Comparison of serum high-molecular weight (HMW) adiponectin with total adiponectin concentrations in type 2 diabetic patients with coronary artery disease using a novel enzyme-linked immunosorbent assay to detect HMW adiponectin
    • Aso, Y., Yamamoto, R., Wakabayashi, S. et al. (2006) Comparison of serum high-molecular weight (HMW) adiponectin with total adiponectin concentrations in type 2 diabetic patients with coronary artery disease using a novel enzyme-linked immunosorbent assay to detect HMW adiponectin. Diabetes, 55, 1954-60.
    • (2006) Diabetes , vol.55 , pp. 1954-1960
    • Aso, Y.1    Yamamoto, R.2    Wakabayashi, S.3
  • 7
    • 0842313004 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients
    • Bajaj, M., Suraamornkul, S., Piper, P. et al. (2004) Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients. The Journal of Clinical Endocrinology and Metabolism, 89, 200-6.
    • (2004) The Journal of Clinical Endocrinology and Metabolism , vol.89 , pp. 200-206
    • Bajaj, M.1    Suraamornkul, S.2    Piper, P.3
  • 8
    • 0036144672 scopus 로고    scopus 로고
    • Stromal cells are the main plasminogen activator inhibitor-1-producing cells in human fat: evidence of differences between visceral and subcutaneous deposits
    • Bastelica, D., Morange, P., Berthet, B. et al. (2002) Stromal cells are the main plasminogen activator inhibitor-1-producing cells in human fat: evidence of differences between visceral and subcutaneous deposits. Arteriosclerosis, Thrombosis, and Vascular Biology, 22, 173-8.
    • (2002) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.22 , pp. 173-178
    • Bastelica, D.1    Morange, P.2    Berthet, B.3
  • 10
    • 33744949934 scopus 로고    scopus 로고
    • Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training
    • Blüher, M., Bullen, J.W., Jr., Lee, J.H. et al. (2006) Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training. The Journal of Clinical Endocrinology and Metabolism, 91, 2310-6.
    • (2006) The Journal of Clinical Endocrinology and Metabolism , vol.91 , pp. 2310-2316
    • Blüher, M.1    Bullen Jr., J.W.2    Lee, J.H.3
  • 11
    • 24144453059 scopus 로고    scopus 로고
    • Changes of adiponectin oligomer composition by moderate weight reduction
    • Bobbert, T., Rochlitz, H., Wegewitz, U. et al. (2005) Changes of adiponectin oligomer composition by moderate weight reduction. Diabetes, 54, 2712-9.
    • (2005) Diabetes , vol.54 , pp. 2712-2719
    • Bobbert, T.1    Rochlitz, H.2    Wegewitz, U.3
  • 12
    • 20144380036 scopus 로고    scopus 로고
    • Ape-lin, a newly identified adipokine up-regulated by insulin and obesity
    • Boucher, J., Masri, B., Daviaud, D. et al. (2005) Ape-lin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology, 146, 1764-1.
    • (2005) Endocrinology , vol.146 , pp. 1764-1761
    • Boucher, J.1    Masri, B.2    Daviaud, D.3
  • 14
    • 3042786130 scopus 로고    scopus 로고
    • Angio-genesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice
    • Brakenhielm, E., Cao, R., Gao, B. et al. (2004) Angio-genesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice. Circulation Research, 94, 1579-88.
    • (2004) Circulation Research , vol.94 , pp. 1579-1588
    • Brakenhielm, E.1    Cao, R.2    Gao, B.3
  • 15
    • 33644699965 scopus 로고    scopus 로고
    • The stimulatory effect of globular adi-ponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects
    • Bruce, C.R., Mertz, V.A., Heigenhauser, G.J. and Dyck, D.J. (2005) The stimulatory effect of globular adi-ponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects. Diabetes, 54, 3154-60.
    • (2005) Diabetes , vol.54 , pp. 3154-3160
    • Bruce, C.R.1    Mertz, V.A.2    Heigenhauser, G.J.3    Dyck, D.J.4
  • 16
    • 0348048487 scopus 로고    scopus 로고
    • Higher production of IL-8 in visceral vs. subcutaneous adipose tissue. Implication of nonadipose cells in adipose tissue
    • Bruun, J.M., Lihn, A.S., Madan, A.K. et al. (2004) Higher production of IL-8 in visceral vs. subcutaneous adipose tissue. Implication of nonadipose cells in adipose tissue. American Journal of Physiology. Endocrinology and Metabolism, 286, E8-13.
    • (2004) American Journal of Physiology. Endocrinology and Metabolism , vol.286
    • Bruun, J.M.1    Lihn, A.S.2    Madan, A.K.3
  • 17
    • 20044384512 scopus 로고    scopus 로고
    • Proposed involvement of adipocyte glyceroneogenesis and phosphoenolpyruvate carboxykinase in the metabolic syndrome
    • Cadoudal, T., Leroyer, S., Reis, A.F. et al. (2005) Proposed involvement of adipocyte glyceroneogenesis and phosphoenolpyruvate carboxykinase in the metabolic syndrome. Biochimie, 87, 27-32.
    • (2005) Biochimie , vol.87 , pp. 27-32
    • Cadoudal, T.1    Leroyer, S.2    Reis, A.F.3
  • 18
    • 23644450775 scopus 로고    scopus 로고
    • Reduction of macrophage infiltration and chemoat-tractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss
    • Cancello, R., Henegar, C., Viguerie, N. et al. (2005) Reduction of macrophage infiltration and chemoat-tractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. Diabetes, 54, 2277-86.
    • (2005) Diabetes , vol.54 , pp. 2277-2286
    • Cancello, R.1    Henegar, C.2    Viguerie, N.3
  • 19
    • 33748314535 scopus 로고    scopus 로고
    • Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity
    • Cancello, R., Tordjman, J., Poitou, C. et al. (2006) Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity. Diabetes, 55, 1554-61.
    • (2006) Diabetes , vol.55 , pp. 1554-1561
    • Cancello, R.1    Tordjman, J.2    Poitou, C.3
  • 20
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade-a unifying system for energy control
    • Carling, D. (2004) The AMP-activated protein kinase cascade-a unifying system for energy control. Trends in Biochemical Sciences, 29, 18-24.
    • (2004) Trends in Biochemical Sciences , vol.29 , pp. 18-24
    • Carling, D.1
  • 21
    • 21244474452 scopus 로고    scopus 로고
    • Adipose tissues as an ancestral immune organ: site-specific change in obesity
    • Caspar-Bauguil, S., Cousin, B., Galinier, A. et al. (2005) Adipose tissues as an ancestral immune organ: site-specific change in obesity. FEBS Letters, 579, 3487-92.
    • (2005) FEBS Letters , vol.579 , pp. 3487-3492
    • Caspar-Bauguil, S.1    Cousin, B.2    Galinier, A.3
  • 22
    • 30044448374 scopus 로고    scopus 로고
    • Direct metabolic regulation in skeletal muscle and fat tissue by leptin: implications for glucose and fatty acids homeostasis
    • Ceddia, R.B. (2005) Direct metabolic regulation in skeletal muscle and fat tissue by leptin: implications for glucose and fatty acids homeostasis. International Journal of Obesity, 29, 1175-83.
    • (2005) International Journal of Obesity , vol.29 , pp. 1175-1183
    • Ceddia, R.B.1
  • 23
    • 32544436435 scopus 로고    scopus 로고
    • The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism
    • Chmurzynska, A. (2006) The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. Journal of Applied Genetics, 47, 39-48.
    • (2006) Journal of Applied Genetics , vol.47 , pp. 39-48
    • Chmurzynska, A.1
  • 24
    • 33646139156 scopus 로고    scopus 로고
    • A pericellular collagenase directs the 3-dimensional development of white adipose tissue
    • Chun, T.H., Hotary, K.B., Sabeh, F., et al. (2006) A pericellular collagenase directs the 3-dimensional development of white adipose tissue. Cell, 125, 577-91.
    • (2006) Cell , vol.125 , pp. 577-591
    • Chun, T.H.1    Hotary, K.B.2    Sabeh, F.3
  • 25
    • 0034885482 scopus 로고    scopus 로고
    • The adipose organ: morphological perspectives of adipose tissues
    • Cinti, S. (2001) The adipose organ: morphological perspectives of adipose tissues. Proceedings of the Nutrition Society, 60, 319-28.
    • (2001) Proceedings of the Nutrition Society , vol.60 , pp. 319-328
    • Cinti, S.1
  • 26
    • 0344450708 scopus 로고    scopus 로고
    • A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
    • Clément, K., Vaisse, C., Lahlou, N. et al. (1998) A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature, 392, 398-401.
    • (1998) Nature , vol.392 , pp. 398-401
    • Clément, K.1    Vaisse, C.2    Lahlou, N.3
  • 27
    • 7744226149 scopus 로고    scopus 로고
    • Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects
    • Clément, K., Viguerie, N., Poitou, C. et al. (2004) Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects. The FASEB Journal, 18, 1657-69.
    • (2004) The FASEB Journal , vol.18 , pp. 1657-1669
    • Clément, K.1    Viguerie, N.2    Poitou, C.3
  • 28
    • 0034693232 scopus 로고    scopus 로고
    • Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice
    • Coburn, C.T., Knapp, F.F., Jr., Febbraio, M. et al. (2000) Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. The Journal of Biological Chemistry, 275, 32523-9.
    • (2000) The Journal of Biological Chemistry , vol.275 , pp. 32523-32529
    • Coburn, C.T.1    Knapp Jr., F.F.2    Febbraio, M.3
  • 29
    • 0345171460 scopus 로고    scopus 로고
    • Enzymes of triac-ylglycerol synthesis and their regulation
    • Coleman, R.A. and Lee, D.P. (2004) Enzymes of triac-ylglycerol synthesis and their regulation. Progress in Lipid Research, 43, 134-76.
    • (2004) Progress in Lipid Research , vol.43 , pp. 134-176
    • Coleman, R.A.1    Lee, D.P.2
  • 30
    • 37649014797 scopus 로고    scopus 로고
    • Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity
    • Couturier, C., Sarkis, C., Séron, K. et al. (2007) Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America, 104, 19476-81.
    • (2007) Proceedings of the National Academy of Sciences of the United States of America , vol.104 , pp. 19476-19481
    • Couturier, C.1    Sarkis, C.2    Séron, K.3
  • 31
    • 33845299821 scopus 로고    scopus 로고
    • Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells
    • Crossno, J.T., Jr., Majka, S.M., Grazia, T. et al. (2006) Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells. The Journal of Clinical Investigation, 116, 3220-8.
    • (2006) The Journal of Clinical Investigation , vol.116 , pp. 3220-3228
    • Crossno Jr., J.T.1    Majka, S.M.2    Grazia, T.3
  • 32
    • 2342537773 scopus 로고    scopus 로고
    • From blood monocytes to adipose tissue-resident macrophages: induction of diapedesis by human mature adipocytes
    • Curat, C.A., Miranville, A., Sengenes, C. et al. (2004) From blood monocytes to adipose tissue-resident macrophages: induction of diapedesis by human mature adipocytes. Diabetes, 53, 1285-92.
    • (2004) Diabetes , vol.53 , pp. 1285-1292
    • Curat, C.A.1    Miranville, A.2    Sengenes, C.3
  • 33
    • 33644826101 scopus 로고    scopus 로고
    • Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin
    • Curat, C.A., Wegner, V., Sengenes, C. et al. (2006) Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin. Diabetologia, 49, 744-7.
    • (2006) Diabetologia , vol.49 , pp. 744-747
    • Curat, C.A.1    Wegner, V.2    Sengenes, C.3
  • 34
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • Després, J.P. and Lemieux, I. (2006) Abdominal obesity and metabolic syndrome. Nature, 444, 881-7.
    • (2006) Nature , vol.444 , pp. 881-887
    • Després, J.P.1    Lemieux, I.2
  • 35
    • 0025219410 scopus 로고
    • A diet high in fat stimulates adipocyte proliferation in older (22 month) rats
    • Ellis, J.R., McDonald, R.B. and Stern, J.S. (1990) A diet high in fat stimulates adipocyte proliferation in older (22 month) rats. Experimental Gerontology, 25, 141-8.
    • (1990) Experimental Gerontology , vol.25 , pp. 141-148
    • Ellis, J.R.1    McDonald, R.B.2    Stern, J.S.3
  • 36
    • 33846201363 scopus 로고    scopus 로고
    • Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells
    • Fain, J.N. (2006) Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Vitamins and Hormones, 74, 443-77.
    • (2006) Vitamins and Hormones , vol.74 , pp. 443-477
    • Fain, J.N.1
  • 37
    • 2042480671 scopus 로고    scopus 로고
    • Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans
    • Fain, J.N., Madan, A.K., Hiler, M.L. et al. (2004) Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans. Endocrinology, 145, 2273-82.
    • (2004) Endocrinology , vol.145 , pp. 2273-2282
    • Fain, J.N.1    Madan, A.K.2    Hiler, M.L.3
  • 38
    • 33846409122 scopus 로고    scopus 로고
    • Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor
    • Farooqi, I.S., Wangensteen, T., Collins, S. et al. (2007) Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor. The New England Journal of Medicine, 356, 237-47.
    • (2007) The New England Journal of Medicine , vol.356 , pp. 237-247
    • Farooqi, I.S.1    Wangensteen, T.2    Collins, S.3
  • 40
    • 0033516477 scopus 로고    scopus 로고
    • A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism
    • Febbraio, M., Abumrad, N.A., Hajjar, D.P. et al. (1999) A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. The Journal of Biological Chemistry, 274, 19055-62.
    • (1999) The Journal of Biological Chemistry , vol.274 , pp. 19055-19062
    • Febbraio, M.1    Abumrad, N.A.2    Hajjar, D.P.3
  • 41
    • 0032464788 scopus 로고    scopus 로고
    • Lipoprotein lipase and the disposition of dietary fatty acids
    • Fielding, B.A. and Frayn, K.N. (1998) Lipoprotein lipase and the disposition of dietary fatty acids. The British Journal of Nutrition, 80, 495-502.
    • (1998) The British Journal of Nutrition , vol.80 , pp. 495-502
    • Fielding, B.A.1    Frayn, K.N.2
  • 42
    • 21344463079 scopus 로고    scopus 로고
    • Serum high molecular weight complex of adiponectin correlates better with glucose tolerance than total serum adiponectin in Indo-Asian males
    • Fisher, F.F., Trujillo, M.E., Hanif, W. et al. (2005) Serum high molecular weight complex of adiponectin correlates better with glucose tolerance than total serum adiponectin in Indo-Asian males. Diabetologia, 48, 1084-7.
    • (2005) Diabetologia , vol.48 , pp. 1084-1087
    • Fisher, F.F.1    Trujillo, M.E.2    Hanif, W.3
  • 43
    • 34047155003 scopus 로고    scopus 로고
    • Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
    • Fontana, L., Eagon, J.C., Trujillo, M. et al. (2007) Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes, 56, 1010-3.
    • (2007) Diabetes , vol.56 , pp. 1010-1013
    • Fontana, L.1    Eagon, J.C.2    Trujillo, M.3
  • 44
    • 0014846847 scopus 로고
    • Weight loss during fasting: implications for the obese
    • Forbes, G.B. (1970) Weight loss during fasting: implications for the obese. The American Journal of Clinical Nutrition, 23, 1212-9.
    • (1970) The American Journal of Clinical Nutrition , vol.23 , pp. 1212-1219
    • Forbes, G.B.1
  • 45
    • 0036381998 scopus 로고    scopus 로고
    • Adipose tissue as a buffer for daily lipid flux
    • Frayn, K.N. (2002) Adipose tissue as a buffer for daily lipid flux. Diabetologia, 45, 1201-10.
    • (2002) Diabetologia , vol.45 , pp. 1201-1210
    • Frayn, K.N.1
  • 46
    • 0022477311 scopus 로고
    • Hormone-sensitive lipase and monoacylglycerol lipase are both required for complete degradation of adipocyte triacylglycerol
    • Fredrikson, G., Tornqvist, H. and Belfrage, P. (1986) Hormone-sensitive lipase and monoacylglycerol lipase are both required for complete degradation of adipocyte triacylglycerol. Biochimica et Biophysica Acta, 876, 288-93.
    • (1986) Biochimica et Biophysica Acta , vol.876 , pp. 288-293
    • Fredrikson, G.1    Tornqvist, H.2    Belfrage, P.3
  • 47
    • 19944433652 scopus 로고    scopus 로고
    • Visfatin: a protein secreted by visceral fat that mimics the effects of insulin
    • Retraction: Fukuhara et al. (2007). Science, 318, 565.
    • Fukuhara, A., Matsuda, M., Nishizawa, M. et al. (2005) Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science, 307, 426-30. Retraction: Fukuhara et al. (2007). Science, 318, 565.
    • (2005) Science , vol.307 , pp. 426-430
    • Fukuhara, A.1    Matsuda, M.2    Nishizawa, M.3
  • 48
    • 2942564894 scopus 로고    scopus 로고
    • High expression of complement components in omental adipose tissue in obese men
    • Gabrielsson, B.G., Johansson, J.M., Lonn, M. et al. (2003) High expression of complement components in omental adipose tissue in obese men. Obesity Research, 11, 699-708.
    • (2003) Obesity Research , vol.11 , pp. 699-708
    • Gabrielsson, B.G.1    Johansson, J.M.2    Lonn, M.3
  • 50
    • 0032923359 scopus 로고    scopus 로고
    • Localization of adipocyte long-chain fatty acyl-CoA synthetase at the plasma membrane
    • Gargiulo, C.E., Stuhlsatz-Krouper, S.M. and Schaffer, J.E. (1999) Localization of adipocyte long-chain fatty acyl-CoA synthetase at the plasma membrane. Journal of Lipid Research, 40, 881-92.
    • (1999) Journal of Lipid Research , vol.40 , pp. 881-892
    • Gargiulo, C.E.1    Stuhlsatz-Krouper, S.M.2    Schaffer, J.E.3
  • 52
    • 0034289797 scopus 로고    scopus 로고
    • The human uncoupling protein-1 gene (UCP1): present status and perspectives in obesity research
    • Gonzalez-Barroso, M., Ricquier, D. and Cassard-Doulcier, A.M. (2000) The human uncoupling protein-1 gene (UCP1): present status and perspectives in obesity research. Obesity Reviews, 1, 61-72.
    • (2000) Obesity Reviews , vol.1 , pp. 61-72
    • Gonzalez-Barroso, M.1    Ricquier, D.2    Cassard-Doulcier, A.M.3
  • 53
    • 33745095399 scopus 로고    scopus 로고
    • Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects
    • Graham, T.E., Yang, Q., Blüher, M. et al. (2006) Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. The New England Journal of Medicine, 354, 2552-63.
    • (2006) The New England Journal of Medicine , vol.354 , pp. 2552-2563
    • Graham, T.E.1    Yang, Q.2    Blüher, M.3
  • 54
  • 56
    • 0036797450 scopus 로고    scopus 로고
    • A futile metabolic cycle activated in adipocytes by antidiabetic agents
    • Guan, H.P., Li, Y., Jensen, M.V. et al. (2002) A futile metabolic cycle activated in adipocytes by antidiabetic agents. Nature Medicine, 8, 1122-8.
    • (2002) Nature Medicine , vol.8 , pp. 1122-1128
    • Guan, H.P.1    Li, Y.2    Jensen, M.V.3
  • 57
    • 0036401857 scopus 로고    scopus 로고
    • Fatty acid transport across membranes: relevance to nutrition and metabolic pathology
    • Hajri, T. and Abumrad, N.A. (2002) Fatty acid transport across membranes: relevance to nutrition and metabolic pathology. Annual Review of Nutrition, 22, 383-415.
    • (2002) Annual Review of Nutrition , vol.22 , pp. 383-415
    • Hajri, T.1    Abumrad, N.A.2
  • 59
    • 33745854236 scopus 로고    scopus 로고
    • Measurement of the high-molecular weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome
    • Hara, K., Horikoshi, M., Yamauchi, T. et al. (2006) Measurement of the high-molecular weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome. Diabetes Care, 29, 1357-62.
    • (2006) Diabetes Care , vol.29 , pp. 1357-1362
    • Hara, K.1    Horikoshi, M.2    Yamauchi, T.3
  • 60
    • 0025260137 scopus 로고
    • Brown adipose tissue thermogenesis: interdisciplinary studies
    • Himms-Hagen, J. (1990) Brown adipose tissue thermogenesis: interdisciplinary studies. The FASEB Journal, 4, 2890-8.
    • (1990) The FASEB Journal , vol.4 , pp. 2890-2898
    • Himms-Hagen, J.1
  • 61
    • 33750153292 scopus 로고    scopus 로고
    • Attenuation of leptin and insulin signaling by SOCS proteins
    • Howard, J.K. and Flier, J.S. (2006) Attenuation of leptin and insulin signaling by SOCS proteins. Trends in Endocrinology and Metabolism, 17, 365-71.
    • (2006) Trends in Endocrinology and Metabolism , vol.17 , pp. 365-371
    • Howard, J.K.1    Flier, J.S.2
  • 62
    • 15044356709 scopus 로고    scopus 로고
    • The role of the adipocyte hormone adiponectin in cardiovascular disease
    • Hug, C. and Lodish, H.F. (2005) The role of the adipocyte hormone adiponectin in cardiovascular disease. Current Opinion in Pharmacology, 5, 129-34.
    • (2005) Current Opinion in Pharmacology , vol.5 , pp. 129-134
    • Hug, C.1    Lodish, H.F.2
  • 63
    • 10344262633 scopus 로고    scopus 로고
    • Identification, cloning, expression, and purification of three novel human calcium-independent phospho-lipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
    • Jenkins, C.M., Mancuso, D.J., Yan, W. et al. (2004) Identification, cloning, expression, and purification of three novel human calcium-independent phospho-lipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. The Journal of Biological Chemistry, 279, 48968-75.
    • (2004) The Journal of Biological Chemistry , vol.279 , pp. 48968-48975
    • Jenkins, C.M.1    Mancuso, D.J.2    Yan, W.3
  • 64
    • 0033103069 scopus 로고    scopus 로고
    • Areas of fat loss in overweight young females following an 8-week period of energy intake reduction
    • Jones, P.R. and Edwards, D.A. (1999) Areas of fat loss in overweight young females following an 8-week period of energy intake reduction. Annals of Human Biology, 26, 151-62.
    • (1999) Annals of Human Biology , vol.26 , pp. 151-162
    • Jones, P.R.1    Edwards, D.A.2
  • 65
    • 12144279575 scopus 로고    scopus 로고
    • Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance
    • Kabir, M., Catalano, K.J., Ananthnarayan, S. et al. (2005) Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance. American Journal of Physiology. Endocrinology and Metabolism, 288, E454-61.
    • (2005) American Journal of Physiology. Endocrinology and Metabolism , vol.288
    • Kabir, M.1    Catalano, K.J.2    Ananthnarayan, S.3
  • 66
    • 18844432308 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors
    • Kadowaki, T. and Yamauchi, T. (2005) Adiponectin and adiponectin receptors. Endocrine Reviews, 26, 439-51.
    • (2005) Endocrine Reviews , vol.26 , pp. 439-451
    • Kadowaki, T.1    Yamauchi, T.2
  • 67
    • 33745834319 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors in insulin resistance, diabetes and the metabolic syndrome
    • Kadowaki, T., Yamauchi, T., Kubota, N. et al. (2006) Adiponectin and adiponectin receptors in insulin resistance, diabetes and the metabolic syndrome. The Journal of Clinical Investigation, 116, 1784-92.
    • (2006) The Journal of Clinical Investigation , vol.116 , pp. 1784-1792
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3
  • 68
    • 20844451123 scopus 로고    scopus 로고
    • AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism
    • Kahn, B.B., Alquier, T., Carling, D. and Hardie, D.G. (2005) AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metabolism, 1, 15-25.
    • (2005) Cell Metabolism , vol.1 , pp. 15-25
    • Kahn, B.B.1    Alquier, T.2    Carling, D.3    Hardie, D.G.4
  • 69
    • 2942564118 scopus 로고    scopus 로고
    • The nicotinic acid receptor-a new mechanism for an old drug
    • Karpe, F. and Frayn, K.N. (2004) The nicotinic acid receptor-a new mechanism for an old drug. Lancet, 363, 1892-4.
    • (2004) Lancet , vol.363 , pp. 1892-1894
    • Karpe, F.1    Frayn, K.N.2
  • 70
    • 2942703809 scopus 로고    scopus 로고
    • Reversal of obesity by targeted ablation of adipose tissue
    • Kolonin, M.G., Saha, P.K., Chan, L. et al. (2004) Reversal of obesity by targeted ablation of adipose tissue. Nature Medicine, 10, 625-32.
    • (2004) Nature Medicine , vol.10 , pp. 625-632
    • Kolonin, M.G.1    Saha, P.K.2    Chan, L.3
  • 71
    • 10744231067 scopus 로고    scopus 로고
    • Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian
    • Krakoff, J., Funahashi, T., Stehouwer, C.D. et al. (2003) Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian. Diabetes Care, 26, 1745-51.
    • (2003) Diabetes Care , vol.26 , pp. 1745-1751
    • Krakoff, J.1    Funahashi, T.2    Stehouwer, C.D.3
  • 72
    • 0031560437 scopus 로고    scopus 로고
    • Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability
    • Kuriyama, H., Kawamoto, S., Ishida, N. et al. (1997) Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability. Biochemical and Biophysical Research Communications, 241, 53-8.
    • (1997) Biochemical and Biophysical Research Communications , vol.241 , pp. 53-58
    • Kuriyama, H.1    Kawamoto, S.2    Ishida, N.3
  • 73
    • 0038341767 scopus 로고    scopus 로고
    • Do regional differences in adipocyte biology provide new pathophysiological insights?
    • Lafontan, M. and Berlan, M. (2003) Do regional differences in adipocyte biology provide new pathophysiological insights? Trends in Pharmacological Sciences, 24, 276-83.
    • (2003) Trends in Pharmacological Sciences , vol.24 , pp. 276-283
    • Lafontan, M.1    Berlan, M.2
  • 74
    • 33750515920 scopus 로고    scopus 로고
    • Role of adipo-kines in the control of energy metabolism: focus on adiponectin
    • Lafontan, M. and Viguerie, N. (2006) Role of adipo-kines in the control of energy metabolism: focus on adiponectin. Current Opinion in Pharmacology, 6, 580-5.
    • (2006) Current Opinion in Pharmacology , vol.6 , pp. 580-585
    • Lafontan, M.1    Viguerie, N.2
  • 75
    • 33748871923 scopus 로고    scopus 로고
    • Importance of TNF-alpha and neutral lipases in human adipose tissue lipolysis
    • Langin, D. and Arner, P. (2006) Importance of TNF-alpha and neutral lipases in human adipose tissue lipolysis. Trends in Endocrinology and Metabolism, 17, 314-20.
    • (2006) Trends in Endocrinology and Metabolism , vol.17 , pp. 314-320
    • Langin, D.1    Arner, P.2
  • 76
    • 30744477567 scopus 로고    scopus 로고
    • Adipocyte lipases and defect of lipolysis in human obesity
    • Langin, D., Dicker, A., Tavernier, G. et al. (2005) Adipocyte lipases and defect of lipolysis in human obesity. Diabetes, 54, 3190-7.
    • (2005) Diabetes , vol.54 , pp. 3190-3197
    • Langin, D.1    Dicker, A.2    Tavernier, G.3
  • 77
    • 0034470182 scopus 로고    scopus 로고
    • Millenium fat-cell lipolysis reveals unsuspected novel tracks
    • Langin, D., Lucas, S. and Lafontan, M. (2000) Millenium fat-cell lipolysis reveals unsuspected novel tracks. Hormone and Metabolic Research, 32, 443-52.
    • (2000) Hormone and Metabolic Research , vol.32 , pp. 443-452
    • Langin, D.1    Lucas, S.2    Lafontan, M.3
  • 78
    • 33644760456 scopus 로고    scopus 로고
    • Adi-ponectin multimeric complexes and the metabolic syndrome trait cluster
    • Lara-Castro, C., Luo, N., Wallace, P. et al. (2006) Adi-ponectin multimeric complexes and the metabolic syndrome trait cluster. Diabetes, 55, 249-59.
    • (2006) Diabetes , vol.55 , pp. 249-259
    • Lara-Castro, C.1    Luo, N.2    Wallace, P.3
  • 79
    • 33646128723 scopus 로고    scopus 로고
    • Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome
    • Lass, A., Zimmermann, R., Haemmerle, G. et al. (2006) Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. Cell Metabolism, 3, 309-19.
    • (2006) Cell Metabolism , vol.3 , pp. 309-319
    • Lass, A.1    Zimmermann, R.2    Haemmerle, G.3
  • 80
    • 0002493340 scopus 로고
    • Brown adipose tissue in man
    • in, (eds P. Trayhurn and D.G. Nicholls), Edward Arnold, London
    • Lean, M.E.J. and James, W.P.T. (1986) Brown adipose tissue in man, in Brown Adipose Tissue (eds P. Trayhurn and D.G. Nicholls), Edward Arnold, London, pp. 339-65
    • (1986) Brown Adipose Tissue , pp. 339-365
    • Lean, M.E.J.1    James, W.P.T.2
  • 81
    • 33744953147 scopus 로고    scopus 로고
    • Rosiglitazone controls fatty acid cycling in human adipose tissue by means of glyceroneogenesis and glycerol phosphorylation
    • Leroyer, S.N., Tordjman, J., Chauvet, G. et al. (2006) Rosiglitazone controls fatty acid cycling in human adipose tissue by means of glyceroneogenesis and glycerol phosphorylation. The Journal of Biological Chemistry, 281, 13141-9.
    • (2006) The Journal of Biological Chemistry , vol.281 , pp. 13141-13149
    • Leroyer, S.N.1    Tordjman, J.2    Chauvet, G.3
  • 82
    • 12144289998 scopus 로고    scopus 로고
    • Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism and behavior in leptin-deficient adults
    • Licinio, J., Caglayan, S., Ozata, M. et al. (2004) Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism and behavior in leptin-deficient adults. Proceedings of the National Academy of Sciences of the United States of America, 101, 4531-6.
    • (2004) Proceedings of the National Academy of Sciences of the United States of America , vol.101 , pp. 4531-4536
    • Licinio, J.1    Caglayan, S.2    Ozata, M.3
  • 83
    • 0842347854 scopus 로고    scopus 로고
    • Differentially expressed genes in visceral and subcutaneous adipose tissue of obese men and women
    • Linder, K., Arner, P., Flores-Morales, A. et al. (2004) Differentially expressed genes in visceral and subcutaneous adipose tissue of obese men and women. Progress in Lipid Research, 45, 148-54.
    • (2004) Progress in Lipid Research , vol.45 , pp. 148-154
    • Linder, K.1    Arner, P.2    Flores-Morales, A.3
  • 84
    • 33847650121 scopus 로고    scopus 로고
    • Identification of common pathways mediating differentiation of bone marrow-and adipose tissue-derived human mesenchymal stem cells into three mesenchymal lineages
    • Liu, T.M., Martina, M., Hutmacher, D.W. et al. (2007) Identification of common pathways mediating differentiation of bone marrow-and adipose tissue-derived human mesenchymal stem cells into three mesenchymal lineages. Stem Cells (Dayton, Ohio), 25, 750-60.
    • (2007) Stem Cells (Dayton, Ohio) , vol.25 , pp. 750-760
    • Liu, T.M.1    Martina, M.2    Hutmacher, D.W.3
  • 85
    • 33745815985 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling in metabolic regulation
    • Long, Y.C. and Zierath, J.R. (2006) AMP-activated protein kinase signaling in metabolic regulation. The Journal of Clinical Investigation, 116, 1776-83.
    • (2006) The Journal of Clinical Investigation , vol.116 , pp. 1776-1783
    • Long, Y.C.1    Zierath, J.R.2
  • 86
    • 0027731309 scopus 로고
    • Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
    • Lowell, B.B., S-Susulic, V., Hamann, A. et al. (1993) Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature, 366, 740-2.
    • (1993) Nature , vol.366 , pp. 740-742
    • Lowell, B.B.1    S-Susulic, V.2    Hamann, A.3
  • 87
    • 33744972277 scopus 로고    scopus 로고
    • APPL1 binds to adiponectin receptors and mediates adipo-nectin signalling and function
    • Mao, X., Kikani, C.K., Riojas, R.A. et al. (2006) APPL1 binds to adiponectin receptors and mediates adipo-nectin signalling and function. Nature Cell Biology, 8, 516-23.
    • (2006) Nature Cell Biology , vol.8 , pp. 516-523
    • Mao, X.1    Kikani, C.K.2    Riojas, R.A.3
  • 88
    • 33744904687 scopus 로고    scopus 로고
    • The phosphorylation of serine 492 of perilipin A directs lipid droplet fragmentation and dispersion
    • Marcinkiewicz, A., Gauthier, D., Garcia, A. and Brasaemle, D.L. (2006) The phosphorylation of serine 492 of perilipin A directs lipid droplet fragmentation and dispersion. The Journal of Biological Chemistry, 281, 11901-9.
    • (2006) The Journal of Biological Chemistry , vol.281 , pp. 11901-11909
    • Marcinkiewicz, A.1    Gauthier, D.2    Garcia, A.3    Brasaemle, D.L.4
  • 89
    • 0033671833 scopus 로고    scopus 로고
    • Absence of perilipin results in leanness and reverses obesity in Leprdb/db mice
    • Martinez-Botas, J., Anderson, J.B., Tessier, D. et al. (2000) Absence of perilipin results in leanness and reverses obesity in Leprdb/db mice. Nature Genetics, 26, 474-9.
    • (2000) Nature Genetics , vol.26 , pp. 474-479
    • Martinez-Botas, J.1    Anderson, J.B.2    Tessier, D.3
  • 92
    • 34948899219 scopus 로고    scopus 로고
    • The transcriptional coactivator peroxisome proliferator activated receptor (PPAR) gamma coactivator-1 alpha and the nuclear receptor PPAR alpha control the expression of glycerol kinase and metabolism genes independently of PPAR gamma activation in human white adipocytes
    • Mazzucotelli, A., Viguerie, N., Tiraby, C. et al. (2007) The transcriptional coactivator peroxisome proliferator activated receptor (PPAR) gamma coactivator-1 alpha and the nuclear receptor PPAR alpha control the expression of glycerol kinase and metabolism genes independently of PPAR gamma activation in human white adipocytes. Diabetes, 56, 2467-75.
    • (2007) Diabetes , vol.56 , pp. 2467-2475
    • Mazzucotelli, A.1    Viguerie, N.2    Tiraby, C.3
  • 93
    • 3242695063 scopus 로고    scopus 로고
    • Improvement of postnatal neovascularization by human adipose tissue-derived stem cells
    • Miranville, A., Heeschen, C., Sengenes, C. et al. (2004) Improvement of postnatal neovascularization by human adipose tissue-derived stem cells. Circulation, 110, 349-55.
    • (2004) Circulation , vol.110 , pp. 349-355
    • Miranville, A.1    Heeschen, C.2    Sengenes, C.3
  • 94
    • 33744944318 scopus 로고    scopus 로고
    • Perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-dependent and-independent mechanisms
    • Miyoshi, H., Souza, S.C., Zhang, H.H. et al. (2006) Perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-dependent and-independent mechanisms. The Journal of Biological Chemistry, 281, 15837-44.
    • (2006) The Journal of Biological Chemistry , vol.281 , pp. 15837-15844
    • Miyoshi, H.1    Souza, S.C.2    Zhang, H.H.3
  • 95
    • 33847714769 scopus 로고    scopus 로고
    • Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes
    • Miyoshi, H., Perfield, J.W., Souza, S.C. et al. (2007) Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes. The Journal of Biological Chemistry, 282, 996-1002.
    • (2007) The Journal of Biological Chemistry , vol.282 , pp. 996-1002
    • Miyoshi, H.1    Perfield, J.W.2    Souza, S.C.3
  • 96
    • 0030878110 scopus 로고    scopus 로고
    • Congenital leptin deficiency is associated with severe early-onset obesity in humans
    • Montague, C.T., Farooqi, I.S., Whitehead, J.P. et al. (1997) Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature, 387, 903-8.
    • (1997) Nature , vol.387 , pp. 903-908
    • Montague, C.T.1    Farooqi, I.S.2    Whitehead, J.P.3
  • 97
    • 30044438117 scopus 로고    scopus 로고
    • Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase
    • Moore, H.P., Silver, R.B., Mottillo, E.P. et al. (2005) Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase. The Journal of Biological Chemistry, 280, 43109-20.
    • (2005) The Journal of Biological Chemistry , vol.280 , pp. 43109-43120
    • Moore, H.P.1    Silver, R.B.2    Mottillo, E.P.3
  • 98
    • 0036930844 scopus 로고    scopus 로고
    • Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone
    • Motoshima, H., Wu, X., Sinha, M.K. et al. (2002) Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone. The Journal of Clinical Endocrinology and Metabolism, 87, 5662-7.
    • (2002) The Journal of Clinical Endocrinology and Metabolism , vol.87 , pp. 5662-5667
    • Motoshima, H.1    Wu, X.2    Sinha, M.K.3
  • 99
    • 17844401180 scopus 로고    scopus 로고
    • Molecular and anatomical determinants of central leptin resistance
    • Munzberg, H. and Myers, M.G., Jr. (2005) Molecular and anatomical determinants of central leptin resistance. Nature Neuroscience, 8, 566-70.
    • (2005) Nature Neuroscience , vol.8 , pp. 566-570
    • Munzberg, H.1    Myers Jr., M.G.2
  • 101
    • 0029859045 scopus 로고    scopus 로고
    • Regulation of gene expression by insulin
    • O'Brien, R.M. and Granner, D.K. (1996) Regulation of gene expression by insulin. Physiological Reviews, 76, 1109-61.
    • (1996) Physiological Reviews , vol.76 , pp. 1109-1161
    • O'Brien, R.M.1    Granner, D.K.2
  • 102
    • 0030717887 scopus 로고    scopus 로고
    • Uncoupling protein gene: quantification of expression levels in adipose tissues of obese and non-obese humans
    • Oberkofler, H., Dallinger, G., Liu, Y.M. et al. (1997) Uncoupling protein gene: quantification of expression levels in adipose tissues of obese and non-obese humans. Journal of Lipid Research, 38, 2125-33.
    • (1997) Journal of Lipid Research , vol.38 , pp. 2125-2133
    • Oberkofler, H.1    Dallinger, G.2    Liu, Y.M.3
  • 104
    • 0035957040 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages
    • Ouchi, N., Kihara, S., Arita, Y. et al. (2001) Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation, 103, 1057-63.
    • (2001) Circulation , vol.103 , pp. 1057-1063
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 105
    • 0037984387 scopus 로고    scopus 로고
    • Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity
    • Pajvani, U.B., Du, X., Combs, T.P. et al. (2003) Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity. The Journal of Biological Chemistry, 278, 9073-85.
    • (2003) The Journal of Biological Chemistry , vol.278 , pp. 9073-9085
    • Pajvani, U.B.1    Du, X.2    Combs, T.P.3
  • 106
    • 11144355637 scopus 로고    scopus 로고
    • Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity
    • Pajvani, U.B., Hawkins, M., Combs, T.P. et al. (2004) Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. The Journal of Biological Chemistry, 279, 12152-62.
    • (2004) The Journal of Biological Chemistry , vol.279 , pp. 12152-12162
    • Pajvani, U.B.1    Hawkins, M.2    Combs, T.P.3
  • 108
    • 0036114844 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
    • Petersen, K.F., Oral, E.A., Dufour, S. et al. (2002) Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. The Journal of Clinical Investigation, 109, 1345-50.
    • (2002) The Journal of Clinical Investigation , vol.109 , pp. 1345-1350
    • Petersen, K.F.1    Oral, E.A.2    Dufour, S.3
  • 109
    • 0027024043 scopus 로고
    • An evolutionary and functional view of mammalian adipose tissue
    • Pond, C.M. (1992) An evolutionary and functional view of mammalian adipose tissue. Proceedings of the Nutrition Society, 51, 367-77.
    • (1992) Proceedings of the Nutrition Society , vol.51 , pp. 367-377
    • Pond, C.M.1
  • 110
    • 0032776551 scopus 로고    scopus 로고
    • Physiological specialisation of adipose tissue
    • Pond, C.M. (1999) Physiological specialisation of adipose tissue. Progress in Lipid Research, 38, 225-48.
    • (1999) Progress in Lipid Research , vol.38 , pp. 225-248
    • Pond, C.M.1
  • 111
    • 28444483574 scopus 로고    scopus 로고
    • Early influences on human energy regulation: thrifty genotypes and thrifty phenotypes
    • Prentice, A.M. (2005) Early influences on human energy regulation: thrifty genotypes and thrifty phenotypes. Physiology & Behavior, 86, 640-5.
    • (2005) Physiology & Behavior , vol.86 , pp. 640-645
    • Prentice, A.M.1
  • 112
    • 0042330251 scopus 로고    scopus 로고
    • Minireview: The adipocyte-at the crossroads of energy homeostasis, inflammation, and atherosclerosis
    • Rajala, M.W. and Scherer, P.E. (2003) Minireview: The adipocyte-at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology, 144, 3765-73.
    • (2003) Endocrinology , vol.144 , pp. 3765-3773
    • Rajala, M.W.1    Scherer, P.E.2
  • 113
    • 0034668852 scopus 로고    scopus 로고
    • Mitochondrial uncoupling proteins: from mitochondria to the regulation of energy balance
    • Ricquier, D. and Bouillaud, F. (2000) Mitochondrial uncoupling proteins: from mitochondria to the regulation of energy balance. The Journal of Physiology, 529, 3-10.
    • (2000) The Journal of Physiology , vol.529 , pp. 3-10
    • Ricquier, D.1    Bouillaud, F.2
  • 115
    • 0018646453 scopus 로고
    • A role for brown adipose tissue in diet-induced thermogenesis
    • Rothwell, N.J. and Stock, M.J. (1979) A role for brown adipose tissue in diet-induced thermogenesis. Nature, 281, 31-5.
    • (1979) Nature , vol.281 , pp. 31-35
    • Rothwell, N.J.1    Stock, M.J.2
  • 117
    • 33846029180 scopus 로고    scopus 로고
    • Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism
    • Schweiger, M., Schreiber, R., Haemmerle, G. et al. (2006) Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism. The Journal of Biological Chemistry, 281, 40236-41.
    • (2006) The Journal of Biological Chemistry , vol.281 , pp. 40236-40241
    • Schweiger, M.1    Schreiber, R.2    Haemmerle, G.3
  • 118
    • 34347326271 scopus 로고    scopus 로고
    • Transcriptional control of brown fat determination by PRDM16
    • Seale, P., Kajimura, S., Yang, W. et al. (2007) Transcriptional control of brown fat determination by PRDM16. Cell Metabolism, 6, 38-54.
    • (2007) Cell Metabolism , vol.6 , pp. 38-54
    • Seale, P.1    Kajimura, S.2    Yang, W.3
  • 119
    • 50049122271 scopus 로고    scopus 로고
    • PRDM16 controls a brown fat/skeletal muscle switch
    • Seale, P., Bjork, B., Yang, W. et al. (2008) PRDM16 controls a brown fat/skeletal muscle switch. Nature, 454, 961-7.
    • (2008) Nature , vol.454 , pp. 961-967
    • Seale, P.1    Bjork, B.2    Yang, W.3
  • 120
  • 121
    • 24344448623 scopus 로고    scopus 로고
    • Preadipocytes in the human subcutaneous adipose tissue display distinct features from the adult mesenchymal and hematopoietic stem cells
    • Sengenes, C., Lolmede, K., Zakaroff-Girard, A. et al. (2005) Preadipocytes in the human subcutaneous adipose tissue display distinct features from the adult mesenchymal and hematopoietic stem cells. Journal of Cellular Physiology, 205, 114-22.
    • (2005) Journal of Cellular Physiology , vol.205 , pp. 114-122
    • Sengenes, C.1    Lolmede, K.2    Zakaroff-Girard, A.3
  • 122
    • 0038411470 scopus 로고    scopus 로고
    • Adipose quantification by imaging methods: a proposed classification
    • Shen, W., Wangm, Z., Punyanita, M. et al. (2003) Adipose quantification by imaging methods: a proposed classification. Obesity Research, 11, 5-16.
    • (2003) Obesity Research , vol.11 , pp. 5-16
    • Shen, W.1    Wangm, Z.2    Punyanita, M.3
  • 124
    • 10644275883 scopus 로고    scopus 로고
    • Physical association between the adipocyte fatty acid-binding protein and hormone-sensitive lipase: a fluorescence resonance energy transfer analysis
    • Smith, A.J., Sanders, M.A., Thompson, B.R. et al. (2004) Physical association between the adipocyte fatty acid-binding protein and hormone-sensitive lipase: a fluorescence resonance energy transfer analysis. The Journal of Biological Chemistry, 279, 52399-405.
    • (2004) The Journal of Biological Chemistry , vol.279 , pp. 52399-52405
    • Smith, A.J.1    Sanders, M.A.2    Thompson, B.R.3
  • 125
    • 0034103658 scopus 로고    scopus 로고
    • Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat
    • Smith, S.J., Cases, S., Jensen, D.R. et al. (2000) Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat. Nature Genetics, 25, 87-90.
    • (2000) Nature Genetics , vol.25 , pp. 87-90
    • Smith, S.J.1    Cases, S.2    Jensen, D.R.3
  • 126
    • 44849132591 scopus 로고    scopus 로고
    • Dynamics of fat cell turnover in humans
    • Spalding, K.L., Arner, E., Westermark, P.O. et al. (2008) Dynamics of fat cell turnover in humans. Nature, 453, 783-7.
    • (2008) Nature , vol.453 , pp. 783-787
    • Spalding, K.L.1    Arner, E.2    Westermark, P.O.3
  • 127
    • 34347245585 scopus 로고    scopus 로고
    • A nonadaptive scenario explaining the genetic predisposition to obesity: the 'predation release' hypothesis
    • Speakman, J.R. (2007) A nonadaptive scenario explaining the genetic predisposition to obesity: the 'predation release' hypothesis. Cell Metabolism, 6, 5-12.
    • (2007) Cell Metabolism , vol.6 , pp. 5-12
    • Speakman, J.R.1
  • 128
    • 4344713648 scopus 로고    scopus 로고
    • Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism
    • Staiger, H., Kaltenbach, S., Staiger, K. et al. (2004) Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism. Diabetes, 53, 2195-201.
    • (2004) Diabetes , vol.53 , pp. 2195-2201
    • Staiger, H.1    Kaltenbach, S.2    Staiger, K.3
  • 130
    • 0035905758 scopus 로고    scopus 로고
    • The hormone resistin links obesity to diabetes
    • Steppan, C.M., Bailey, S.T., Bhat, S. et al. (2001) The hormone resistin links obesity to diabetes. Nature, 409, 307-312.
    • (2001) Nature , vol.409 , pp. 307-312
    • Steppan, C.M.1    Bailey, S.T.2    Bhat, S.3
  • 131
    • 0034185136 scopus 로고    scopus 로고
    • Comparative study of the lipogenic potential of human and rat adipose tissue
    • Swierczynski, J., Goyke, E., Wach, L. et al. (2000) Comparative study of the lipogenic potential of human and rat adipose tissue. Metabolism: Clinical and Experimental, 49, 594-9.
    • (2000) Metabolism: Clinical and Experimental , vol.49 , pp. 594-599
    • Swierczynski, J.1    Goyke, E.2    Wach, L.3
  • 132
    • 0038379389 scopus 로고    scopus 로고
    • A 'futile cycle' induced by thiazolidinediones in adipose tissue?
    • Tan, G., Debard, C., Tiraby, C. et al. (2003) A 'futile cycle' induced by thiazolidinediones in adipose tissue? Nature Med, 9, 811-2.
    • (2003) Nature Med , vol.9 , pp. 811-812
    • Tan, G.1    Debard, C.2    Tiraby, C.3
  • 133
    • 53549130485 scopus 로고    scopus 로고
    • White fat progenitor cells reside in the adipose vasculature
    • Tang, W., Zeve, D., Suh, J.M. et al. (2008) White fat progenitor cells reside in the adipose vasculature. Science, 322, 583-6.
    • (2008) Science , vol.322 , pp. 583-586
    • Tang, W.1    Zeve, D.2    Suh, J.M.3
  • 134
    • 14344268795 scopus 로고    scopus 로고
    • Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity
    • Tansey, J.T., Sztalryd, C., Gruia-Gray, J. et al. (2001) Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America, 98, 6494-9.
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , pp. 6494-6499
    • Tansey, J.T.1    Sztalryd, C.2    Gruia-Gray, J.3
  • 135
    • 0042357130 scopus 로고    scopus 로고
    • Acquirement of brown fat cell features by human white adipocytes
    • Tiraby, C., Tavernier, G., Lefort, C. et al. (2003) Acquirement of brown fat cell features by human white adipocytes. The Journal of Biological Chemistry, 278, 33370-6.
    • (2003) The Journal of Biological Chemistry , vol.278 , pp. 33370-33376
    • Tiraby, C.1    Tavernier, G.2    Lefort, C.3
  • 136
    • 0037805618 scopus 로고    scopus 로고
    • Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells
    • Tordjman, J., Chauvet, G., Quette, J. et al. (2003) Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells. The Journal of Biological Chemistry, 278, 18785-90.
    • (2003) The Journal of Biological Chemistry , vol.278 , pp. 18785-18790
    • Tordjman, J.1    Chauvet, G.2    Quette, J.3
  • 137
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: inflammation and the pleiotropic role of white adipose tissue
    • Trayhurn, P. and Wood, I.S. (2004) Adipokines: inflammation and the pleiotropic role of white adipose tissue. The British Journal of Nutrition, 92, 347-55.
    • (2004) The British Journal of Nutrition , vol.92 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 138
    • 50049127055 scopus 로고    scopus 로고
    • New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
    • Tseng, Y.H., Kokkotou, E., Schulz, T.J. et al. (2008) New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature, 454, 1000-4.
    • (2008) Nature , vol.454 , pp. 1000-1004
    • Tseng, Y.H.1    Kokkotou, E.2    Schulz, T.J.3
  • 139
    • 0242696221 scopus 로고    scopus 로고
    • Lipid overload and overflow: metabolic trauma and the metabolic syndrome
    • Unger, R. (2003) Lipid overload and overflow: metabolic trauma and the metabolic syndrome. Trends in Endocrinology and Metabolism, 14, 398-403.
    • (2003) Trends in Endocrinology and Metabolism , vol.14 , pp. 398-403
    • Unger, R.1
  • 140
    • 20044377423 scopus 로고    scopus 로고
    • Hyperleptinemia: protecting the heart from lipid overload
    • Unger, R.H. (2005) Hyperleptinemia: protecting the heart from lipid overload. Hypertension, 45, 1031-4.
    • (2005) Hypertension , vol.45 , pp. 1031-1034
    • Unger, R.H.1
  • 141
    • 0035988340 scopus 로고    scopus 로고
    • Understanding adipose tissue development from transgenic animal models
    • Valet, P., Tavernier, G., Castan-Laurell, I. et al. (2002) Understanding adipose tissue development from transgenic animal models. Journal of Lipid Research, 43, 835-60.
    • (2002) Journal of Lipid Research , vol.43 , pp. 835-860
    • Valet, P.1    Tavernier, G.2    Castan-Laurell, I.3
  • 142
    • 0031802865 scopus 로고    scopus 로고
    • Leptin secretion from subcutaneous and visceral adipose tissue in women
    • Van Harmelen, V., Reynisdottir, S., Eriksson, P. et al. (1998) Leptin secretion from subcutaneous and visceral adipose tissue in women. Diabetes, 47, 913-7.
    • (1998) Diabetes , vol.47 , pp. 913-917
    • Van Harmelen, V.1    Reynisdottir, S.2    Eriksson, P.3
  • 143
    • 19944432653 scopus 로고    scopus 로고
    • Adipose tissue gene expression in obese subjects during low-fat and high-fat hypocaloric diets
    • Viguerie, N., Vidal, H., Arner, P. et al. (2005) Adipose tissue gene expression in obese subjects during low-fat and high-fat hypocaloric diets. Diabetolo-gia, 48, 123-31.
    • (2005) Diabetolo-gia , vol.48 , pp. 123-131
    • Viguerie, N.1    Vidal, H.2    Arner, P.3
  • 144
    • 8744297386 scopus 로고    scopus 로고
    • Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis
    • Villena, J.A., Roy, S., Sarkadi-Nagy, E. et al. (2004) Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. The Journal of Biological Chemistry, 279, 47066-75.
    • (2004) The Journal of Biological Chemistry , vol.279 , pp. 47066-47075
    • Villena, J.A.1    Roy, S.2    Sarkadi-Nagy, E.3
  • 145
    • 34347252326 scopus 로고    scopus 로고
    • Plasma levels and adipose tissue mRNA expression of retinol-binding protein 4 are reduced during calorie restriction in obese subjects but are not related to diet-induced changes in insulin sensitivity
    • Vitkova, M., Klimcakova, E., Kovacikova, M. et al. (2007) Plasma levels and adipose tissue mRNA expression of retinol-binding protein 4 are reduced during calorie restriction in obese subjects but are not related to diet-induced changes in insulin sensitivity. The Journal of Clinical Endocrinology and Metabolism, 92, 2330-5.
    • (2007) The Journal of Clinical Endocrinology and Metabolism , vol.92 , pp. 2330-2335
    • Vitkova, M.1    Klimcakova, E.2    Kovacikova, M.3
  • 146
    • 6344260341 scopus 로고    scopus 로고
    • A survey of genes differentially expressed in subcutaneous and visceral adipose tissue in men
    • Vohl, M.C., Sladek, R., Robitaille, J. et al. (2004) A survey of genes differentially expressed in subcutaneous and visceral adipose tissue in men. Obesity Research, 12, 1217-22.
    • (2004) Obesity Research , vol.12 , pp. 1217-1222
    • Vohl, M.C.1    Sladek, R.2    Robitaille, J.3
  • 147
    • 0034504237 scopus 로고    scopus 로고
    • Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome
    • Wajchenberg, B.L. (2000) Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocrine Reviews, 21, 697-738.
    • (2000) Endocrine Reviews , vol.21 , pp. 697-738
    • Wajchenberg, B.L.1
  • 148
    • 33745998066 scopus 로고    scopus 로고
    • Proteomic characterization of human serum proteins associated with the fat-derived hormone adiponectin
    • Wang, Y., Xu, L.Y., Lam, K.S. et al. (2006) Proteomic characterization of human serum proteins associated with the fat-derived hormone adiponectin. Proteomics, 6, 3862-70.
    • (2006) Proteomics , vol.6 , pp. 3862-3870
    • Wang, Y.1    Xu, L.Y.2    Lam, K.S.3
  • 149
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • Weisberg, S.P., McCann, D., Desai, M. et al. (2003) Obesity is associated with macrophage accumulation in adipose tissue. The Journal of Clinical Investigation, 112, 1796-1808.
    • (2003) The Journal of Clinical Investigation , vol.112 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3
  • 150
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu, H., Barnes, G.T., Yang, Q. et al. (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. The Journal of Clinical Investigation, 112, 1821-30.
    • (2003) The Journal of Clinical Investigation , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3
  • 151
    • 33847280286 scopus 로고    scopus 로고
    • T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity
    • Wu, H., Ghosh, S., Perrard, X.D. et al. (2007) T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity. Circulation, 115, 1029-38.
    • (2007) Circulation , vol.115 , pp. 1029-1038
    • Wu, H.1    Ghosh, S.2    Perrard, X.D.3
  • 152
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi, T., Kamon, J., Ito, Y. et al. (2003) Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature, 423, 762-9.
    • (2003) Nature , vol.423 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3
  • 153
    • 22944434929 scopus 로고    scopus 로고
    • Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
    • Yang, Q., Graham, T.E., Mody, N. et al. (2005) Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature, 436, 356-62.
    • (2005) Nature , vol.436 , pp. 356-362
    • Yang, Q.1    Graham, T.E.2    Mody, N.3
  • 154
    • 0037462926 scopus 로고    scopus 로고
    • The gene expression profiling of human visceral adipose tissue and its secretory functions
    • Yang, Y.S., Song, H.D., Li, R.Y. et al. (2003) The gene expression profiling of human visceral adipose tissue and its secretory functions. Biochemical and Biophysical Research Communications, 300, 839-46.
    • (2003) Biochemical and Biophysical Research Communications , vol.300 , pp. 839-846
    • Yang, Y.S.1    Song, H.D.2    Li, R.Y.3
  • 155
    • 0034284038 scopus 로고    scopus 로고
    • Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages
    • Yokota, T., Oritani, K., Takahashi, I. et al. (2000) Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood, 96, 1723-32.
    • (2000) Blood , vol.96 , pp. 1723-1732
    • Yokota, T.1    Oritani, K.2    Takahashi, I.3
  • 156
    • 27644457743 scopus 로고    scopus 로고
    • Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study
    • Yusuf, S., Hawken, S., Ounpuu, S. et al. (2005) Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study. Lancet, 366, 1640-9.
    • (2005) Lancet , vol.366 , pp. 1640-1649
    • Yusuf, S.1    Hawken, S.2    Ounpuu, S.3
  • 158
    • 0031739240 scopus 로고    scopus 로고
    • Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes: relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway
    • Zierath, J., Livingston, J., Thorne, A. et al. (1998) Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes: relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway. Diabetologia, 41, 1343-54.
    • (1998) Diabetologia , vol.41 , pp. 1343-1354
    • Zierath, J.1    Livingston, J.2    Thorne, A.3
  • 159
    • 8844226709 scopus 로고    scopus 로고
    • Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase
    • Zimmermann, R., Strauss, J.G., Haemmerle, G. et al. (2004) Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science, 306, 1383-6.
    • (2004) Science , vol.306 , pp. 1383-1386
    • Zimmermann, R.1    Strauss, J.G.2    Haemmerle, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.