A futile metabolic cycle activated in adipocytes by antidiabetic agents

Nature Medicine

Volumn 8, Issue 10, 2002, Pages 1122-1128

  Guan, Hong Ping ^a   Li, Yong ^a   Jensen, Mette Valentin ^b   Newgard, Christopher B ^b   Steppan, Claire M ^a   Lazar, Mitchell A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 BROMOPALMITIC ACID; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; CIGLITAZONE; FATTY ACID; GLYCEROL KINASE; ISOPRENALINE; PD 068235; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; RECEPTOR BLOCKING AGENT; ROSIGLITAZONE; TRIACYLGLYCEROL; TROGLITAZONE; UNCLASSIFIED DRUG;

ADIPOCYTE; ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL METABOLISM; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; FATTY ACID METABOLISM; GENE EXPRESSION; GENE INDUCTION; INSULIN SENSITIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADIPOCYTES; ANIMALS; CELL LINE; DIABETES MELLITUS, TYPE 2; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION REGULATION; GLYCEROL; GLYCEROL KINASE; HUMANS; HYPOGLYCEMIC AGENTS; LIGANDS; MICE; MICE, INBRED C57BL; MICE, OBESE; RATS; RATS, SPRAGUE-DAWLEY; RATS, ZUCKER; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SUBSTRATE CYCLING; THIAZOLES; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS; TRIGLYCERIDES;

ANIMALIA;

EID: 0036797450     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm780     Document Type: Article

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