High expression of complement components in omental adipose tissue in obese men

Obesity Research

Volumn 11, Issue 6, 2003, Pages 699-708

  Gabrielsson, Britt G ^a   Johansson, Jenny M ^a   Lönn, Malin ^a   Jernås, Margareta ^a   Olbers, Torsten ^a   Peltonen, Markku ^a   Larsson, Ingrid ^a   Lönn, Lars ^a   Sjöström, Lars ^a   Carlsson, Björn ^a   Carlsson, Lena M S ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Body composition; DNA microarray; Real time polymerase chain reaction; Serum C3; Serum C4

Indexed keywords

EID: 2942564894     PISSN: 10717323     EISSN: None     Source Type: Journal    
DOI: 10.1038/oby.2003.100     Document Type: Article

References (39)

1. Kissebah AH. Intra-abdominal fat: is it a major factor in developing diabetes and coronary artery disease? Diabetes Res Clin Pract. 1996;30(suppl):25-30.
2. Björntorp P. Metabolic implications of body fat distribution. Diabetes Care. 1991;14:1132-43.
3. Montague CT, O'Rahilly S. The perils of portliness: causes and consequences of visceral adiposity. Diabetes. 2000;49:883-8.
4. Gabriely I, Ma XH, Yang XM, et al. Removal of visceral fat prevents insulin resistance and glucose intolerance of aging. Diabetes.2002;51:2951-8.
5. Thorne A, Lonnqvist F, Apelman J, Hellers G, Arner P. A pilot study of long-term effects of a novel obesity treatment: omentectomy in connection with adjustable gastric banding. Int J Obes Relat Metab Disord. 2002;26:193-9.
6. Fried SK, Bunkin DA, Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab. 1998;83:847-50.
7. Alessi MC, Peiretti F, Morange P, Henry M, Nalbone G, Juhan-Vague I. Production of plasminogen activator inhibitor 1 by human adipose tissue: possible link between visceral fat accumulation and vascular disease. Diabetes. 1997;46:860-7.
8. Van Harmelen V, Reynisdottir S, Eriksson P, et al. Leptin secretion from subcutaneous and visceral adipose tissue in women. Diabetes. 1998;47:913-917.
9. Lefebvre AM, Laville M, Vega N, et al. Depot-specific differences in adipose tissue gene expression in lean and obese subjects. Diabetes. 1998;47:98-103.
10. Imbeault P, Vidal H, Tremblay A, et al. Age-related differences in messenger ribonucleic acid expression of key proteins involved in adipose cell differentiation and metabolism. J Clin Endocrinol Metab. 2001;86:828-33.
11. Montague CT, Prins JB, Sanders L et al. Depot-related gene expression in human subcutaneous and omental adipocytes. Diabetes. 1998;47:1384-91.
12. Dusserre E, Moulin P, Vidal H. Differences in mRNA expression of the proteins secreted by the adipocytes in human subcutaneous and visceral adipose tissues. Biochim Biophys Acta. 2000;1500:88-96.
13. Eriksson P, Van Harmelen V, Hoffstedt J, et al. Regional variation in plasminogen activator inhibitor-1 expression in adipose tissue from obese individuals. Thromb Haemost. 2000;83:545-8.
14. Gabrielsson BG, Johansson JM, Jennische E, et al. Depot-specific expression of fibroblast growth factors in human adipose tissue. Obes Res. 2002;10:608-16.
15. Yudkin JS, Stehouwer CDA, Emeis JJ, Coppack SW. C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol. 1999;19:972-8.
16. Smith U, Sjöström L, Björntorp P. Comparison of two methods for determining human adipose cell size. J Lipid Res. 1972;13:822-4.
17. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156-9.
18. Morgan BP, Gasque P. Extrahepatic complement biosynthesis: where, when and why? Clin Exp Immunol. 1997;107:1-7.
19. Halkes CJM, van Dijk H, de Jaegere PPT, et al. Postprandial increase of complement component 3 in normolipidemic patients with coronary artery disease: effects of expanded-dose simvastatin. Arterioscler Thromb Vasc Biol. 2001;21:1526-30.
20. Choy LN, Rosen BS, Spiegelman BM. Adipsin and an endogenous pathway of complement from adipose cells. J Biol Chem. 1992;267:12736-41.
21. Cianflone K, Maslowska M. Differentiation-induced production of ASP in human adipocytes. Eur J Clin Invest. 1995;25:817-25.
22. Peake PW, O'Grady S, Pussell BA, Charlesworth JA. Detection and quantification of the control proteins of the alternative pathway of complement in 3T3-L1 adipocytes. Eur J Clin Invest. 1997;27:922-7.
23. Cianflone K, Roncari DA, Maslowska M, Baldo A, Forden J, Sniderman AD. Adipsin/acylation stimulating protein system in human adipocytes: regulation of triacylglycerol synthesis. Biochemistry. 1994;33:9489-95.
24. Maslowska M, Sniderman AD, Germinario R, Cianflone K. ASP stimulates glucose transport in cultured human adipocytes. Int J Obes Relat Metab Disord. 1997;21:261-6.
25. Pickup JC, Crook MA. Is type II diabetes mellitus a disease of the innate immune system? Diabetologia. 1998;41:1241-8.
26. Muscari A, Massarelli G, Bastagli L, et al. Relationship of serum C3 to fasting insulin, risk factors and previous ischaemic events in middle-aged men. Eur Heart J. 2000;21:1081-90.
27. Lemieux I, Pascot A, Prud'homme D, et al. Elevated C-reactive protein: another component of the atherothrombotic profile of abdominal obesity. Arterioscler Thromb Vasc Biol 2001;21:961-967.
28. Weyer C, Tataranni PA, Pratley RE. Insulin action and insulinemia are closely related to the fasting complement C3, but not acylation stimulating protein concentration. Diabetes Care. 2000;23:779-85.
29. Koistinen HA, Koivisto VA, Ebeling P. Serum complement protein C3 concentration is elevated in insulin resistance in obese men. Eur J Int Med. 2000;11:21-6.
30. Ridker PM, Rifai N, Rose L, Buring JE, Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med. 2002;347:1557-65.
31. Pond CM. Long-term changes in adipose tissue in human disease. Proc Nutr Soc. 2001;60:365-74.
32. Volanakis JE. Transcriptional regulation of complement genes. Ann Rev Immunol. 1995;13:277-305.
33. White RT, Damm D, Hancock N, et al. Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue. J Biol Chem. 1992;267:9210-3.
34. Pomeroy C, Mitchell J, Eckert E, Raymond N, Crosby R, Dalmasso AP. Effect of body weight and caloric restriction on serum complement proteins, including Factor D/adipsin: studies in anorexia nervosa and obesity. Clin Exp Immunol. 1997;108:507-15.
35. Saleh J, Summers LK, Cianflone K, Fielding BA, Sniderman AD, Frayn KN. Coordinated release of acylation stimulating protein (ASP) and triacylglycerol clearance by human adipose tissue in vivo in the postprandial period. J Lipid Res. 1998;39:884-91.
36. Gabrielsson BG, Carlsson B, Carlsson LMS. Partial genome scale analysis of gene expression in human adipose tissue using DNA array. Obes Res. 2000;8:374-384.
37. Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002;287:356-9.
38. Corominola H, Conner LJ, Beavers LS, et al. Identification of novel genes differentially expressed in omental fat of obese subjects and obese type 2 diabetic patients. Diabetes. 2001;50:2822-30.
39. van Hinsbergh VWH, Kooistra T, Scheffer MA, van Bockel JH, van Muijen GNP. Characterization and fibrinolytic properties of human omental tissue mesothelial cells: comparison with endothelial cells. Blood. 1990;75:1490-7.