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Volumn 67, Issue 18, 2010, Pages 3115-3130

Combining naturally occurring polyphenols with TNF-related apoptosis-inducing ligand: A promising approach to kill resistant cancer cells?

Author keywords

Apoptosis; Cancer; DR4; DR5; Flavonoid; Polyphenol; Stilbene; TRAIL

Indexed keywords

APIGENIN; BAICALEIN; BUTEIN; CHALCONE DERIVATIVE; CURCUMIN; DAIDZEIN; EPIGALLOCATECHIN GALLATE; FLAVANOL DERIVATIVE; FLAVANONE DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOID; FLAVONOL DERIVATIVE; FLAVONOLIGNAN; GENISTEIN; HONOKIOL; ISOLIQUIRITIGENIN; KAEMPFEROL; LIGNAN; LUTEOLIN; MYRICETIN; NORDIHYDROGUAIARETIC ACID; POLYPHENOL; QUERCETIN; RESVERATROL; SILIBININ; STILBENE DERIVATIVE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; UNINDEXED DRUG; WOGONIN; ANTINEOPLASTIC AGENT; PHENOL DERIVATIVE; POLYPHENOLS;

EID: 77956642345     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0407-6     Document Type: Review
Times cited : (55)

References (144)
  • 1
    • 49049086338 scopus 로고    scopus 로고
    • Ligand-based targeting of apoptosis in cancer: The potential of recombinant human apoptosis ligand 2/tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL)
    • 1:CAS:528:DC%2BD1cXpvVWmtbw%3D 18640940
    • A Ashkenazi P Holland SG Eckhardt 2008 Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL) J Clin Oncol 26 3621 3630 1:CAS:528:DC%2BD1cXpvVWmtbw%3D 18640940
    • (2008) J Clin Oncol , vol.26 , pp. 3621-3630
    • Ashkenazi, A.1    Holland, P.2    Eckhardt, S.G.3
  • 2
    • 76349085626 scopus 로고    scopus 로고
    • Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer
    • 1:CAS:528:DC%2BC3cXhsVSrs7s%3D 20068564
    • T Trarbach M Moehler V Heinemann CH Kohne M Przyborek C Schulz V Sneller G Gallant S Kanzler 2010 Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer Br J Cancer 102 506 512 1:CAS:528:DC%2BC3cXhsVSrs7s%3D 20068564
    • (2010) Br J Cancer , vol.102 , pp. 506-512
    • Trarbach, T.1    Moehler, M.2    Heinemann, V.3    Kohne, C.H.4    Przyborek, M.5    Schulz, C.6    Sneller, V.7    Gallant, G.8    Kanzler, S.9
  • 3
    • 62449166171 scopus 로고    scopus 로고
    • Is TRAIL the holy grail of cancer therapy?
    • 1:CAS:528:DC%2BD1MXivFSns7Y%3D 19194800
    • T Newsom-Davis S Prieske H Walczak 2009 Is TRAIL the holy grail of cancer therapy? Apoptosis 14 607 623 1:CAS:528:DC%2BD1MXivFSns7Y%3D 19194800
    • (2009) Apoptosis , vol.14 , pp. 607-623
    • Newsom-Davis, T.1    Prieske, S.2    Walczak, H.3
  • 5
    • 0034812659 scopus 로고    scopus 로고
    • Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: Characterization of in vivo efficacy, pharmacokinetics, and safety
    • 1:CAS:528:DC%2BD3MXntFWltrw%3D 11561060
    • SK Kelley LA Harris D Xie L Deforge K Totpal J Bussiere JA Fox 2001 Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: characterization of in vivo efficacy, pharmacokinetics, and safety J Pharmacol Exp Ther 299 31 38 1:CAS:528:DC%2BD3MXntFWltrw%3D 11561060
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 31-38
    • Kelley, S.K.1    Harris, L.A.2    Xie, D.3    Deforge, L.4    Totpal, K.5    Bussiere, J.6    Fox, J.A.7
  • 7
    • 33745854287 scopus 로고    scopus 로고
    • The role of the TRAIL/TRAIL receptors system in hematopoiesis and endothelial cell biology
    • 1:CAS:528:DC%2BD28XntFSgsbw%3D 16750931
    • G Zauli P Secchiero 2006 The role of the TRAIL/TRAIL receptors system in hematopoiesis and endothelial cell biology Cytokine Growth Factor Rev 17 245 257 1:CAS:528:DC%2BD28XntFSgsbw%3D 16750931
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 245-257
    • Zauli, G.1    Secchiero, P.2
  • 8
    • 33746493900 scopus 로고    scopus 로고
    • The molecular biology of TRAIL-mediated signaling and its potential therapeutic exploitation in hematopoietic malignancies
    • 1:CAS:528:DC%2BD28XnslOksr0%3D 16918339
    • S Boehrer D Nowak D Hoelzer PS Mitrou KU Chow 2006 The molecular biology of TRAIL-mediated signaling and its potential therapeutic exploitation in hematopoietic malignancies Curr Med Chem 13 2091 2100 1:CAS:528: DC%2BD28XnslOksr0%3D 16918339
    • (2006) Curr Med Chem , vol.13 , pp. 2091-2100
    • Boehrer, S.1    Nowak, D.2    Hoelzer, D.3    Mitrou, P.S.4    Chow, K.U.5
  • 9
    • 33645091240 scopus 로고    scopus 로고
    • TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer
    • 1:CAS:528:DC%2BD28Xhs1CqsLk%3D 16405656
    • E Cretney A Shanker H Yagita MJ Smyth TJ Sayers 2006 TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer Immunol Cell Biol 84 87 98 1:CAS:528:DC%2BD28Xhs1CqsLk%3D 16405656
    • (2006) Immunol Cell Biol , vol.84 , pp. 87-98
    • Cretney, E.1    Shanker, A.2    Yagita, H.3    Smyth, M.J.4    Sayers, T.J.5
  • 12
    • 0036467427 scopus 로고    scopus 로고
    • Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
    • 1:CAS:528:DC%2BD38XpsFektw%3D%3D 11801676
    • E Cretney K Takeda H Yagita M Glaccum JJ Peschon MJ Smyth 2002 Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice J Immunol 168 1356 1361 1:CAS:528:DC%2BD38XpsFektw%3D%3D 11801676
    • (2002) J Immunol , vol.168 , pp. 1356-1361
    • Cretney, E.1    Takeda, K.2    Yagita, H.3    Glaccum, M.4    Peschon, J.J.5    Smyth, M.J.6
  • 14
    • 51049122396 scopus 로고    scopus 로고
    • Metastasis suppressor function of tumor necrosis factor-related apoptosis-inducing ligand-R in mice: Implications for TRAIL-based therapy in humans?
    • 1:CAS:528:DC%2BD1cXpt1Sqtrk%3D 18676822
    • A Grosse-Wilde CJ Kemp 2008 Metastasis suppressor function of tumor necrosis factor-related apoptosis-inducing ligand-R in mice: implications for TRAIL-based therapy in humans? Cancer Res 68 6035 6037 1:CAS:528: DC%2BD1cXpt1Sqtrk%3D 18676822
    • (2008) Cancer Res , vol.68 , pp. 6035-6037
    • Grosse-Wilde, A.1    Kemp, C.J.2
  • 15
    • 58149171658 scopus 로고    scopus 로고
    • Conjunctival sac fluid contains elevated levels of soluble TRAIL: Implications for the anti-tumoral surveillance of the anterior surface of the eye
    • 1:CAS:528:DC%2BD1cXhsFahsbfE 18780288
    • P Secchiero G Lamberti F Corallini E Melloni C Guarnotta A Sebastiani G Zauli 2009 Conjunctival sac fluid contains elevated levels of soluble TRAIL: implications for the anti-tumoral surveillance of the anterior surface of the eye J Cell Physiol 218 199 204 1:CAS:528:DC%2BD1cXhsFahsbfE 18780288
    • (2009) J Cell Physiol , vol.218 , pp. 199-204
    • Secchiero, P.1    Lamberti, G.2    Corallini, F.3    Melloni, E.4    Guarnotta, C.5    Sebastiani, A.6    Zauli, G.7
  • 17
    • 0036899204 scopus 로고    scopus 로고
    • Detection of soluble TRAIL in HBV infected patients and its clinical implications
    • 1:CAS:528:DC%2BD38XpvVSnsrk%3D 12439929
    • LH Han WS Sun CH Ma LN Zhang SX Liu Q Zhang LF Gao YH Chen 2002 Detection of soluble TRAIL in HBV infected patients and its clinical implications World J Gastroenterol 8 1077 1080 1:CAS:528:DC%2BD38XpvVSnsrk%3D 12439929
    • (2002) World J Gastroenterol , vol.8 , pp. 1077-1080
    • Han, L.H.1    Sun, W.S.2    Ma, C.H.3    Zhang, L.N.4    Liu, S.X.5    Zhang, Q.6    Gao, L.F.7    Chen, Y.H.8
  • 18
    • 0032550366 scopus 로고    scopus 로고
    • Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
    • 1:CAS:528:DyaK1cXis1Cru7o%3D 9547332
    • P Schneider N Holler JL Bodmer M Hahne K Frei A Fontana J Tschopp 1998 Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity J Exp Med 187 1205 1213 1:CAS:528:DyaK1cXis1Cru7o%3D 9547332
    • (1998) J Exp Med , vol.187 , pp. 1205-1213
    • Schneider, P.1    Holler, N.2    Bodmer, J.L.3    Hahne, M.4    Frei, K.5    Fontana, A.6    Tschopp, J.7
  • 20
    • 0031406386 scopus 로고    scopus 로고
    • Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway
    • 1:CAS:528:DyaK1cXjsFWrsQ%3D%3D 9430227
    • PM Chaudhary M Eby A Jasmin A Bookwalter J Murray L Hood 1997 Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway Immunity 7 821 830 1:CAS:528:DyaK1cXjsFWrsQ%3D%3D 9430227
    • (1997) Immunity , vol.7 , pp. 821-830
    • Chaudhary, P.M.1    Eby, M.2    Jasmin, A.3    Bookwalter, A.4    Murray, J.5    Hood, L.6
  • 23
    • 0030770614 scopus 로고    scopus 로고
    • Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL
    • 1:CAS:528:DyaK2sXms1Cqsr4%3D 9325248
    • M MacFarlane M Ahmad SM Srinivasula T Fernandes-Alnemri GM Cohen ES Alnemri 1997 Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL J Biol Chem 272 25417 25420 1:CAS:528:DyaK2sXms1Cqsr4%3D 9325248
    • (1997) J Biol Chem , vol.272 , pp. 25417-25420
    • MacFarlane, M.1    Ahmad, M.2    Srinivasula, S.M.3    Fernandes-Alnemri, T.4    Cohen, G.M.5    Alnemri, E.S.6
  • 24
    • 0030869432 scopus 로고    scopus 로고
    • Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
    • 1:CAS:528:DyaK2sXmsFaqs70%3D 9314565
    • MA Degli-Esposti PJ Smolak H Walczak J Waugh CP Huang RF DuBose RG Goodwin CA Smith 1997 Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family J Exp Med 186 1165 1170 1:CAS:528:DyaK2sXmsFaqs70%3D 9314565
    • (1997) J Exp Med , vol.186 , pp. 1165-1170
    • Degli-Esposti, M.A.1    Smolak, P.J.2    Walczak, H.3    Waugh, J.4    Huang, C.P.5    Dubose, R.F.6    Goodwin, R.G.7    Smith, C.A.8
  • 25
    • 0030762815 scopus 로고    scopus 로고
    • An antagonist decoy receptor and a death domain-containing receptor for TRAIL
    • 1:CAS:528:DyaK2sXlt1eksro%3D 9242610
    • G Pan J Ni YF Wei G Yu R Gentz VM Dixit 1997 An antagonist decoy receptor and a death domain-containing receptor for TRAIL Science 277 815 818 1:CAS:528:DyaK2sXlt1eksro%3D 9242610
    • (1997) Science , vol.277 , pp. 815-818
    • Pan, G.1    Ni, J.2    Wei, Y.F.3    Yu, G.4    Gentz, R.5    Dixit, V.M.6
  • 26
    • 0031414749 scopus 로고    scopus 로고
    • The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
    • 1:CAS:528:DyaK1cXjsFWgtQ%3D%3D 9430226
    • MA Degli-Esposti WC Dougall PJ Smolak JY Waugh CA Smith RG Goodwin 1997 The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain Immunity 7 813 820 1:CAS:528:DyaK1cXjsFWgtQ%3D%3D 9430226
    • (1997) Immunity , vol.7 , pp. 813-820
    • Degli-Esposti, M.A.1    Dougall, W.C.2    Smolak, P.J.3    Waugh, J.Y.4    Smith, C.A.5    Goodwin, R.G.6
  • 29
    • 0036859738 scopus 로고    scopus 로고
    • Defining characteristics of types i and II apoptotic cells in response to TRAIL
    • 12407450
    • N Ozoren WS El-Deiry 2002 Defining characteristics of types I and II apoptotic cells in response to TRAIL Neoplasia 4 551 557 12407450
    • (2002) Neoplasia , vol.4 , pp. 551-557
    • Ozoren, N.1    El-Deiry, W.S.2
  • 30
    • 0036131142 scopus 로고    scopus 로고
    • Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
    • 1:CAS:528:DC%2BD38Xit1Cisb8%3D 11875499
    • H LeBlanc D Lawrence E Varfolomeev K Totpal J Morlan P Schow S Fong R Schwall D Sinicropi A Ashkenazi 2002 Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax Nat Med 8 274 281 1:CAS:528:DC%2BD38Xit1Cisb8%3D 11875499
    • (2002) Nat Med , vol.8 , pp. 274-281
    • Leblanc, H.1    Lawrence, D.2    Varfolomeev, E.3    Totpal, K.4    Morlan, J.5    Schow, P.6    Fong, S.7    Schwall, R.8    Sinicropi, D.9    Ashkenazi, A.10
  • 31
    • 0033529534 scopus 로고    scopus 로고
    • Differential modulation of apoptosis sensitivity in CD95 type i and type II cells
    • 1:CAS:528:DyaK1MXlt1CnsLg%3D 10428830
    • C Scaffidi I Schmitz J Zha SJ Korsmeyer PH Krammer ME Peter 1999 Differential modulation of apoptosis sensitivity in CD95 type I and type II cells J Biol Chem 274 22532 22538 1:CAS:528:DyaK1MXlt1CnsLg%3D 10428830
    • (1999) J Biol Chem , vol.274 , pp. 22532-22538
    • Scaffidi, C.1    Schmitz, I.2    Zha, J.3    Korsmeyer, S.J.4    Krammer, P.H.5    Peter, M.E.6
  • 32
    • 3042743700 scopus 로고    scopus 로고
    • Regulation of TRAIL-induced apoptosis by ectopic expression of antiapoptotic factors
    • 1:CAS:528:DC%2BD2cXltlKgtb8%3D 15110190
    • BB Aggarwal U Bhardwaj Y Takada 2004 Regulation of TRAIL-induced apoptosis by ectopic expression of antiapoptotic factors Vitam Horm 67 453 483 1:CAS:528:DC%2BD2cXltlKgtb8%3D 15110190
    • (2004) Vitam Horm , vol.67 , pp. 453-483
    • Aggarwal, B.B.1    Bhardwaj, U.2    Takada, Y.3
  • 34
    • 4544253226 scopus 로고    scopus 로고
    • Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity
    • 1:CAS:528:DC%2BD2cXnvVaktLw%3D 15367674
    • MS Ricci Z Jin M Dews D Yu A Thomas-Tikhonenko DT Dicker WS El-Deiry 2004 Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity Mol Cell Biol 24 8541 8555 1:CAS:528:DC%2BD2cXnvVaktLw%3D 15367674
    • (2004) Mol Cell Biol , vol.24 , pp. 8541-8555
    • Ricci, M.S.1    Jin, Z.2    Dews, M.3    Yu, D.4    Thomas-Tikhonenko, A.5    Dicker, D.T.6    El-Deiry, W.S.7
  • 35
    • 0041853690 scopus 로고    scopus 로고
    • Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    • 1:CAS:528:DC%2BD3sXlvFCgu7Y%3D 12887920
    • O Micheau J Tschopp 2003 Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes Cell 114 181 190 1:CAS:528: DC%2BD3sXlvFCgu7Y%3D 12887920
    • (2003) Cell , vol.114 , pp. 181-190
    • Micheau, O.1    Tschopp, J.2
  • 36
    • 33749164762 scopus 로고    scopus 로고
    • Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2
    • 1:CAS:528:DC%2BD28XhtVCltbnK 16980609
    • D Merino N Lalaoui A Morizot P Schneider E Solary O Micheau 2006 Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2 Mol Cell Biol 26 7046 7055 1:CAS:528:DC%2BD28XhtVCltbnK 16980609
    • (2006) Mol Cell Biol , vol.26 , pp. 7046-7055
    • Merino, D.1    Lalaoui, N.2    Morizot, A.3    Schneider, P.4    Solary, E.5    Micheau, O.6
  • 37
    • 62749084512 scopus 로고    scopus 로고
    • Palmitoylation of the TRAIL receptor DR4 confers an efficient TRAIL-induced cell death signalling
    • 1:CAS:528:DC%2BD1MXjtVShu7k%3D 19090789 (2 p following 192)
    • A Rossin M Derouet F Abdel-Sater AO Hueber 2009 Palmitoylation of the TRAIL receptor DR4 confers an efficient TRAIL-induced cell death signalling Biochem J 419 185 192 1:CAS:528:DC%2BD1MXjtVShu7k%3D 19090789 (2 p following 192)
    • (2009) Biochem J , vol.419 , pp. 185-192
    • Rossin, A.1    Derouet, M.2    Abdel-Sater, F.3    Hueber, A.O.4
  • 39
    • 38449118214 scopus 로고    scopus 로고
    • Glycosylation modulates TRAIL-R1/death receptor 4 protein: Different regulations of two pro-apoptotic receptors for TRAIL by tunicamycin
    • 1:CAS:528:DC%2BD2sXhtlKhsr%2FK 17914579
    • T Yoshida T Shiraishi M Horinaka M Wakada T Sakai 2007 Glycosylation modulates TRAIL-R1/death receptor 4 protein: different regulations of two pro-apoptotic receptors for TRAIL by tunicamycin Oncol Rep 18 1239 1242 1:CAS:528:DC%2BD2sXhtlKhsr%2FK 17914579
    • (2007) Oncol Rep , vol.18 , pp. 1239-1242
    • Yoshida, T.1    Shiraishi, T.2    Horinaka, M.3    Wakada, M.4    Sakai, T.5
  • 40
    • 42749092258 scopus 로고    scopus 로고
    • TRAIL receptor-targeted therapeutics: Resistance mechanisms and strategies to avoid them
    • 1:CAS:528:DC%2BD1cXlslWqtbY%3D 18374623
    • A Thorburn K Behbakht H Ford 2008 TRAIL receptor-targeted therapeutics: resistance mechanisms and strategies to avoid them Drug Resist Updat 11 17 24 1:CAS:528:DC%2BD1cXlslWqtbY%3D 18374623
    • (2008) Drug Resist Updat , vol.11 , pp. 17-24
    • Thorburn, A.1    Behbakht, K.2    Ford, H.3
  • 41
    • 14644437742 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAIL-induced apoptosis in cancer
    • 1:CAS:528:DC%2BD2MXhtlahsLc%3D 15550937
    • L Zhang B Fang 2005 Mechanisms of resistance to TRAIL-induced apoptosis in cancer Cancer Gene Ther 12 228 237 1:CAS:528:DC%2BD2MXhtlahsLc%3D 15550937
    • (2005) Cancer Gene Ther , vol.12 , pp. 228-237
    • Zhang, L.1    Fang, B.2
  • 42
    • 3042665524 scopus 로고    scopus 로고
    • Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation
    • 1:CAS:528:DC%2BD2cXkvFWlsro%3D 15205314
    • M Kim SY Park HS Pai TH Kim TR Billiar DW Seol 2004 Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation Cancer Res 64 4078 4081 1:CAS:528: DC%2BD2cXkvFWlsro%3D 15205314
    • (2004) Cancer Res , vol.64 , pp. 4078-4081
    • Kim, M.1    Park, S.Y.2    Pai, H.S.3    Kim, T.H.4    Billiar, T.R.5    Seol, D.W.6
  • 43
    • 64049103030 scopus 로고    scopus 로고
    • TRAIL receptor signalling and modulation: Are we on the right TRAIL?
    • 1:CAS:528:DC%2BD1MXksVantrY%3D 19117685
    • D Mahalingam E Szegezdi M Keane S Jong A Samali 2009 TRAIL receptor signalling and modulation: are we on the right TRAIL? Cancer Treat Rev 35 280 288 1:CAS:528:DC%2BD1MXksVantrY%3D 19117685
    • (2009) Cancer Treat Rev , vol.35 , pp. 280-288
    • Mahalingam, D.1    Szegezdi, E.2    Keane, M.3    Jong, S.4    Samali, A.5
  • 45
    • 48649095089 scopus 로고    scopus 로고
    • Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways
    • 1:CAS:528:DC%2BD1cXms1egt7k%3D 18435439
    • S Ramos 2008 Cancer chemoprevention and chemotherapy: dietary polyphenols and signalling pathways Mol Nutr Food Res 52 507 526 1:CAS:528: DC%2BD1cXms1egt7k%3D 18435439
    • (2008) Mol Nutr Food Res , vol.52 , pp. 507-526
    • Ramos, S.1
  • 46
    • 0036183074 scopus 로고    scopus 로고
    • Evidence for consistent patterns between flavonoid structures and cellular activities
    • 1:CAS:528:DC%2BD38Xit1WrtLY%3D 12002801
    • F Depeint JM Gee G Williamson IT Johnson 2002 Evidence for consistent patterns between flavonoid structures and cellular activities Proc Nutr Soc 61 97 103 1:CAS:528:DC%2BD38Xit1WrtLY%3D 12002801
    • (2002) Proc Nutr Soc , vol.61 , pp. 97-103
    • Depeint, F.1    Gee, J.M.2    Williamson, G.3    Johnson, I.T.4
  • 47
    • 46849083081 scopus 로고    scopus 로고
    • Antioxidant and prooxidant properties of a polyphenol-rich extract from Geranium sanguineum L. in vitro and in vivo
    • 18446846
    • M Murzakhmetova S Moldakarimov L Tancheva S Abarova J Serkedjieva 2008 Antioxidant and prooxidant properties of a polyphenol-rich extract from Geranium sanguineum L. in vitro and in vivo Phytother Res 22 746 751 18446846
    • (2008) Phytother Res , vol.22 , pp. 746-751
    • Murzakhmetova, M.1    Moldakarimov, S.2    Tancheva, L.3    Abarova, S.4    Serkedjieva, J.5
  • 48
    • 70349667448 scopus 로고    scopus 로고
    • Clarification of the role of quercetin hydroxyl groups in superoxide generation and cell apoptosis by chemical modification
    • 1:CAS:528:DC%2BD1MXht1Ghu77O 19734664
    • K Sakao M Fujii DX Hou 2009 Clarification of the role of quercetin hydroxyl groups in superoxide generation and cell apoptosis by chemical modification Biosci Biotechnol Biochem 73 2048 2053 1:CAS:528:DC%2BD1MXht1Ghu77O 19734664
    • (2009) Biosci Biotechnol Biochem , vol.73 , pp. 2048-2053
    • Sakao, K.1    Fujii, M.2    Hou, D.X.3
  • 49
    • 0034736046 scopus 로고    scopus 로고
    • Advances in flavonoid research since 1992
    • 1:CAS:528:DC%2BD3cXosFent74%3D 11130659
    • JB Harborne CA Williams 2000 Advances in flavonoid research since 1992 Phytochemistry 55 481 504 1:CAS:528:DC%2BD3cXosFent74%3D 11130659
    • (2000) Phytochemistry , vol.55 , pp. 481-504
    • Harborne, J.B.1    Williams, C.A.2
  • 50
    • 67349235348 scopus 로고    scopus 로고
    • Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs?
    • 1:CAS:528:DC%2BD1MXlt1Kjtrk%3D 19294386
    • S Thomasset N Teller H Cai D Marko DP Berry WP Steward AJ Gescher 2009 Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs? Cancer Chemother Pharmacol 64 201 211 1:CAS:528:DC%2BD1MXlt1Kjtrk%3D 19294386
    • (2009) Cancer Chemother Pharmacol , vol.64 , pp. 201-211
    • Thomasset, S.1    Teller, N.2    Cai, H.3    Marko, D.4    Berry, D.P.5    Steward, W.P.6    Gescher, A.J.7
  • 51
    • 54249083134 scopus 로고    scopus 로고
    • A dietary anthocyanidin delphinidin induces apoptosis of human prostate cancer PC3 cells in vitro and in vivo: Involvement of nuclear factor-kappaB signaling
    • 18922932
    • BB Hafeez IA Siddiqui M Asim A Malik F Afaq VM Adhami M Saleem M Din H Mukhtar 2008 A dietary anthocyanidin delphinidin induces apoptosis of human prostate cancer PC3 cells in vitro and in vivo: involvement of nuclear factor-kappaB signaling Cancer Res 68 8564 8572 18922932
    • (2008) Cancer Res , vol.68 , pp. 8564-8572
    • Hafeez, B.B.1    Siddiqui, I.A.2    Asim, M.3    Malik, A.4    Afaq, F.5    Adhami, V.M.6    Saleem, M.7    Din, M.8    Mukhtar, H.9
  • 52
    • 33745197329 scopus 로고    scopus 로고
    • Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity
    • 1:CAS:528:DC%2BD28XlvVGkt7k%3D 16618699
    • M Ding R Feng SY Wang L Bowman Y Lu Y Qian V Castranova BH Jiang X Shi 2006 Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity J Biol Chem 281 17359 17368 1:CAS:528:DC%2BD28XlvVGkt7k%3D 16618699
    • (2006) J Biol Chem , vol.281 , pp. 17359-17368
    • Ding, M.1    Feng, R.2    Wang, S.Y.3    Bowman, L.4    Lu, Y.5    Qian, Y.6    Castranova, V.7    Jiang, B.H.8    Shi, X.9
  • 53
    • 8144229635 scopus 로고    scopus 로고
    • Induction of apoptosis in human breast adenocarcinoma MCF-7 cells by prodelphinidin B-2 3, 3′-di-O-gallate from Myrica rubra via Fas-mediated pathway
    • 1:CAS:528:DC%2BD2cXpvFOltb8%3D 15525446
    • PL Kuo YL Hsu TC Lin LT Lin CC Lin 2004 Induction of apoptosis in human breast adenocarcinoma MCF-7 cells by prodelphinidin B-2 3, 3′-di-O-gallate from Myrica rubra via Fas-mediated pathway J Pharm Pharmacol 56 1399 1406 1:CAS:528:DC%2BD2cXpvFOltb8%3D 15525446
    • (2004) J Pharm Pharmacol , vol.56 , pp. 1399-1406
    • Kuo, P.L.1    Hsu, Y.L.2    Lin, T.C.3    Lin, L.T.4    Lin, C.C.5
  • 54
    • 32344444354 scopus 로고    scopus 로고
    • Stability and biotransformation of various dietary anthocyanins in vitro
    • 1:CAS:528:DC%2BD28Xis1SgsLo%3D 15834757
    • J Fleschhut F Kratzer G Rechkemmer SE Kulling 2006 Stability and biotransformation of various dietary anthocyanins in vitro Eur J Nutr 45 7 18 1:CAS:528:DC%2BD28Xis1SgsLo%3D 15834757
    • (2006) Eur J Nutr , vol.45 , pp. 7-18
    • Fleschhut, J.1    Kratzer, F.2    Rechkemmer, G.3    Kulling, S.E.4
  • 55
  • 56
    • 55549138348 scopus 로고    scopus 로고
    • Epigalocatechin-3-gallate (EGCG) downregulates PEA15 and thereby augments TRAIL-mediated apoptosis in malignant glioma
    • 1:CAS:528:DC%2BD1cXhtlyiurnE 18948169
    • MD Siegelin A Habel T Gaiser 2008 Epigalocatechin-3-gallate (EGCG) downregulates PEA15 and thereby augments TRAIL-mediated apoptosis in malignant glioma Neurosci Lett 448 161 165 1:CAS:528:DC%2BD1cXhtlyiurnE 18948169
    • (2008) Neurosci Lett , vol.448 , pp. 161-165
    • Siegelin, M.D.1    Habel, A.2    Gaiser, T.3
  • 57
    • 41149143243 scopus 로고    scopus 로고
    • Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis
    • 1:CAS:528:DC%2BD1cXjslWjtr4%3D 17998943
    • IA Siddiqui A Malik VM Adhami M Asim BB Hafeez S Sarfaraz H Mukhtar 2008 Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis Oncogene 27 2055 2063 1:CAS:528: DC%2BD1cXjslWjtr4%3D 17998943
    • (2008) Oncogene , vol.27 , pp. 2055-2063
    • Siddiqui, I.A.1    Malik, A.2    Adhami, V.M.3    Asim, M.4    Hafeez, B.B.5    Sarfaraz, S.6    Mukhtar, H.7
  • 58
    • 60749117598 scopus 로고    scopus 로고
    • Combinatorial effect of epigallocatechin-3-gallate and TRAIL on pancreatic cancer cell death
    • 1:CAS:528:DC%2BD1MXht1Cqtrc%3D 19082499
    • A Basu S Haldar 2009 Combinatorial effect of epigallocatechin-3-gallate and TRAIL on pancreatic cancer cell death Int J Oncol 34 281 286 1:CAS:528:DC%2BD1MXht1Cqtrc%3D 19082499
    • (2009) Int J Oncol , vol.34 , pp. 281-286
    • Basu, A.1    Haldar, S.2
  • 59
    • 77149150612 scopus 로고    scopus 로고
    • EGCG enhances TRAIL-mediated apoptosis in human melanoma A375 cell line
    • 1:CAS:528:DC%2BC3cXjtlKgtw%3D%3D 20037825
    • Q Shen F Tian P Jiang Y Li L Zhang J Lu J Li 2009 EGCG enhances TRAIL-mediated apoptosis in human melanoma A375 cell line J Huazhong Univ Sci Technol Med Sci 29 771 775 1:CAS:528:DC%2BC3cXjtlKgtw%3D%3D 20037825
    • (2009) J Huazhong Univ Sci Technol Med Sci , vol.29 , pp. 771-775
    • Shen, Q.1    Tian, F.2    Jiang, P.3    Li, Y.4    Zhang, L.5    Lu, J.6    Li, J.7
  • 60
    • 55149104161 scopus 로고    scopus 로고
    • Quercetin: Potentials in the prevention and therapy of disease
    • 1:CAS:528:DC%2BD1cXhtFOrtLnJ 18827577
    • SC Bischoff 2008 Quercetin: potentials in the prevention and therapy of disease Curr Opin Clin Nutr Metab Care 11 733 740 1:CAS:528:DC%2BD1cXhtFOrtLnJ 18827577
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , pp. 733-740
    • Bischoff, S.C.1
  • 61
    • 0029999052 scopus 로고    scopus 로고
    • Phase i clinical trial of the flavonoid quercetin: Pharmacokinetics and evidence for in vivo tyrosine kinase inhibition
    • 1:CAS:528:DyaK28Xis1Wltbg%3D 9816216
    • DR Ferry A Smith J Malkhandi DW Fyfe PG deTakats D Anderson J Baker DJ Kerr 1996 Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition Clin Cancer Res 2 659 668 1:CAS:528:DyaK28Xis1Wltbg%3D 9816216
    • (1996) Clin Cancer Res , vol.2 , pp. 659-668
    • Ferry, D.R.1    Smith, A.2    Malkhandi, J.3    Fyfe, D.W.4    Detakats, P.G.5    Anderson, D.6    Baker, J.7    Kerr, D.J.8
  • 62
    • 33847016908 scopus 로고    scopus 로고
    • TRAIL apoptosis is enhanced by quercetin through Akt dephosphorylation
    • 1:CAS:528:DC%2BD2sXhvFGlsr8%3D 17031854
    • YH Kim YJ Lee 2007 TRAIL apoptosis is enhanced by quercetin through Akt dephosphorylation J Cell Biochem 100 998 1009 1:CAS:528:DC%2BD2sXhvFGlsr8%3D 17031854
    • (2007) J Cell Biochem , vol.100 , pp. 998-1009
    • Kim, Y.H.1    Lee, Y.J.2
  • 63
    • 42649100263 scopus 로고    scopus 로고
    • Quercetin augments TRAIL-induced apoptotic death: Involvement of the ERK signal transduction pathway
    • 1:CAS:528:DC%2BD1cXlsFOms7o%3D 18377872
    • YH Kim DH Lee JH Jeong ZS Guo YJ Lee 2008 Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway Biochem Pharmacol 75 1946 1958 1:CAS:528:DC%2BD1cXlsFOms7o%3D 18377872
    • (2008) Biochem Pharmacol , vol.75 , pp. 1946-1958
    • Kim, Y.H.1    Lee, D.H.2    Jeong, J.H.3    Guo, Z.S.4    Lee, Y.J.5
  • 64
    • 34247626395 scopus 로고    scopus 로고
    • Quercetin enhances CD95- and TRAIL-induced apoptosis in leukemia cell lines
    • 1:CAS:528:DC%2BD2sXksFeltL8%3D 17330100
    • M Russo P Nigro R Rosiello R D'Arienzo GL Russo 2007 Quercetin enhances CD95- and TRAIL-induced apoptosis in leukemia cell lines Leukemia 21 1130 1133 1:CAS:528:DC%2BD2sXksFeltL8%3D 17330100
    • (2007) Leukemia , vol.21 , pp. 1130-1133
    • Russo, M.1    Nigro, P.2    Rosiello, R.3    D'Arienzo, R.4    Russo, G.L.5
  • 65
    • 35148854568 scopus 로고    scopus 로고
    • Induction of death receptor 5 and suppression of survivin contribute to sensitization of TRAIL-induced cytotoxicity by quercetin in non-small cell lung cancer cells
    • 1:CAS:528:DC%2BD2sXhtFeqsL7E 17548900
    • W Chen X Wang J Zhuang L Zhang Y Lin 2007 Induction of death receptor 5 and suppression of survivin contribute to sensitization of TRAIL-induced cytotoxicity by quercetin in non-small cell lung cancer cells Carcinogenesis 28 2114 2121 1:CAS:528:DC%2BD2sXhtFeqsL7E 17548900
    • (2007) Carcinogenesis , vol.28 , pp. 2114-2121
    • Chen, W.1    Wang, X.2    Zhuang, J.3    Zhang, L.4    Lin, Y.5
  • 66
    • 57349169369 scopus 로고    scopus 로고
    • Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation
    • 1:CAS:528:DC%2BD1cXhsFaks7fK 18980244
    • JY Kim EH Kim SS Park JH Lim TK Kwon KS Choi 2008 Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation J Cell Biochem 105 1386 1398 1:CAS:528:DC%2BD1cXhsFaks7fK 18980244
    • (2008) J Cell Biochem , vol.105 , pp. 1386-1398
    • Kim, J.Y.1    Kim, E.H.2    Park, S.S.3    Lim, J.H.4    Kwon, T.K.5    Choi, K.S.6
  • 67
    • 34147111354 scopus 로고    scopus 로고
    • A PKC-Sp1 signaling pathway induces early differentiation of human keratinocytes through upregulation of TSG101
    • 1:CAS:528:DC%2BD2sXksV2mtLs%3D 17321722
    • HL You HL Eng SF Hsu CM Chen TC Ye WT Liao MY Huang R Baer JT Cheng 2007 A PKC-Sp1 signaling pathway induces early differentiation of human keratinocytes through upregulation of TSG101 Cell Signal 19 1201 1211 1:CAS:528: DC%2BD2sXksV2mtLs%3D 17321722
    • (2007) Cell Signal , vol.19 , pp. 1201-1211
    • You, H.L.1    Eng, H.L.2    Hsu, S.F.3    Chen, C.M.4    Ye, T.C.5    Liao, W.T.6    Huang, M.Y.7    Baer, R.8    Cheng, J.T.9
  • 68
    • 34748906001 scopus 로고    scopus 로고
    • Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts
    • 1:CAS:528:DC%2BD2sXhtVCgur%2FL 17876056
    • FH Psahoulia KG Drosopoulos L Doubravska L Andera A Pintzas 2007 Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts Mol Cancer Ther 6 2591 2599 1:CAS:528:DC%2BD2sXhtVCgur%2FL 17876056
    • (2007) Mol Cancer Ther , vol.6 , pp. 2591-2599
    • Psahoulia, F.H.1    Drosopoulos, K.G.2    Doubravska, L.3    Andera, L.4    Pintzas, A.5
  • 69
    • 65949095390 scopus 로고    scopus 로고
    • Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells
    • 1:CAS:528:DC%2BD1MXkvFentro%3D 18971417
    • MD Siegelin DE Reuss A Habel A Rami A von Deimling 2009 Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells Neuro Oncol 11 122 131 1:CAS:528:DC%2BD1MXkvFentro%3D 18971417
    • (2009) Neuro Oncol , vol.11 , pp. 122-131
    • Siegelin, M.D.1    Reuss, D.E.2    Habel, A.3    Rami, A.4    Von Deimling, A.5
  • 72
    • 3142583640 scopus 로고    scopus 로고
    • Effect of dietary flavonols on oestrogen receptor transactivation and cell death induction
    • 1:CAS:528:DC%2BD2cXltlGmu7o%3D 15182386
    • LK Leung LS Po TY Lau YM Yuen 2004 Effect of dietary flavonols on oestrogen receptor transactivation and cell death induction Br J Nutr 91 831 839 1:CAS:528:DC%2BD2cXltlGmu7o%3D 15182386
    • (2004) Br J Nutr , vol.91 , pp. 831-839
    • Leung, L.K.1    Po, L.S.2    Lau, T.Y.3    Yuen, Y.M.4
  • 73
    • 56249131797 scopus 로고    scopus 로고
    • The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin
    • 1:CAS:528:DC%2BD1cXhtlGgs77P 19001439
    • MD Siegelin DE Reuss A Habel C Herold-Mende A von Deimling 2008 The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin Mol Cancer Ther 7 3566 3574 1:CAS:528:DC%2BD1cXhtlGgs77P 19001439
    • (2008) Mol Cancer Ther , vol.7 , pp. 3566-3574
    • Siegelin, M.D.1    Reuss, D.E.2    Habel, A.3    Herold-Mende, C.4    Von Deimling, A.5
  • 74
    • 69849092498 scopus 로고    scopus 로고
    • Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2
    • 1:CAS:528:DC%2BD1MXptlanu78%3D 19398149
    • MD Siegelin T Gaiser A Habel Y Siegelin 2009 Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2 Cancer Lett 283 230 238 1:CAS:528: DC%2BD1MXptlanu78%3D 19398149
    • (2009) Cancer Lett , vol.283 , pp. 230-238
    • Siegelin, M.D.1    Gaiser, T.2    Habel, A.3    Siegelin, Y.4
  • 75
    • 0036682276 scopus 로고    scopus 로고
    • Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II
    • 1:CAS:528:DC%2BD38XlvFelt7k%3D 12154014
    • R Ravi A Bedi 2002 Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II Cancer Res 62 4180 4185 1:CAS:528:DC%2BD38XlvFelt7k%3D 12154014
    • (2002) Cancer Res , vol.62 , pp. 4180-4185
    • Ravi, R.1    Bedi, A.2
  • 76
    • 33646574281 scopus 로고    scopus 로고
    • The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand
    • 1:CAS:528:DC%2BD28XjvFCktrc%3D 16648565
    • M Horinaka T Yoshida T Shiraishi S Nakata M Wakada T Sakai 2006 The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand Mol Cancer Ther 5 945 951 1:CAS:528:DC%2BD28XjvFCktrc%3D 16648565
    • (2006) Mol Cancer Ther , vol.5 , pp. 945-951
    • Horinaka, M.1    Yoshida, T.2    Shiraishi, T.3    Nakata, S.4    Wakada, M.5    Sakai, T.6
  • 78
    • 24744449776 scopus 로고    scopus 로고
    • Protein kinase C inhibition and x-linked inhibitor of apoptosis protein degradation contribute to the sensitization effect of luteolin on tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cancer cells
    • 1:CAS:528:DC%2BD2MXpslaiu70%3D 16140950
    • RX Shi CN Ong HM Shen 2005 Protein kinase C inhibition and x-linked inhibitor of apoptosis protein degradation contribute to the sensitization effect of luteolin on tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cancer cells Cancer Res 65 7815 7823 1:CAS:528:DC%2BD2MXpslaiu70%3D 16140950
    • (2005) Cancer Res , vol.65 , pp. 7815-7823
    • Shi, R.X.1    Ong, C.N.2    Shen, H.M.3
  • 79
    • 33845258748 scopus 로고    scopus 로고
    • Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis
    • 1:CAS:528:DC%2BD28Xht1Kgs7%2FP 16931628
    • SC Fas S Baumann JY Zhu M Giaisi MK Treiber U Mahlknecht PH Krammer M Li-Weber 2006 Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis Blood 108 3700 3706 1:CAS:528:DC%2BD28Xht1Kgs7%2FP 16931628
    • (2006) Blood , vol.108 , pp. 3700-3706
    • Fas, S.C.1    Baumann, S.2    Zhu, J.Y.3    Giaisi, M.4    Treiber, M.K.5    Mahlknecht, U.6    Krammer, P.H.7    Li-Weber, M.8
  • 80
    • 70350346849 scopus 로고    scopus 로고
    • Reactive oxygen species up-regulate p53 and Puma; A possible mechanism for apoptosis during combined treatment with TRAIL and wogonin
    • 1:CAS:528:DC%2BD1MXhtVelt7bN 19438509
    • DH Lee JG Rhee YJ Lee 2009 Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin Br J Pharmacol 157 1189 1202 1:CAS:528:DC%2BD1MXhtVelt7bN 19438509
    • (2009) Br J Pharmacol , vol.157 , pp. 1189-1202
    • Lee, D.H.1    Rhee, J.G.2    Lee, Y.J.3
  • 81
    • 70350336226 scopus 로고    scopus 로고
    • Molecular crosstalk between TRAIL and natural antioxidants in the treatment of cancer
    • 1:CAS:528:DC%2BD1MXhtVelt7bM 19664138
    • SA Rushworth O Micheau 2009 Molecular crosstalk between TRAIL and natural antioxidants in the treatment of cancer Br J Pharmacol 157 1186 1188 1:CAS:528:DC%2BD1MXhtVelt7bM 19664138
    • (2009) Br J Pharmacol , vol.157 , pp. 1186-1188
    • Rushworth, S.A.1    Micheau, O.2
  • 83
    • 67449135860 scopus 로고    scopus 로고
    • Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs
    • 1:CAS:528:DC%2BD1MXnvVWktr4%3D 19397969
    • J Peng Q Qi Q You R Hu W Liu F Feng G Wang Q Guo 2009 Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs J Ethnopharmacol 124 257 262 1:CAS:528:DC%2BD1MXnvVWktr4%3D 19397969
    • (2009) J Ethnopharmacol , vol.124 , pp. 257-262
    • Peng, J.1    Qi, Q.2    You, Q.3    Hu, R.4    Liu, W.5    Feng, F.6    Wang, G.7    Guo, Q.8
  • 84
    • 55349089182 scopus 로고    scopus 로고
    • Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells
    • 1:CAS:528:DC%2BD1cXhtlSkur%2FF 18974136
    • H Taniguchi T Yoshida M Horinaka T Yasuda AE Goda M Konishi M Wakada K Kataoka T Yoshikawa T Sakai 2008 Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells Cancer Res 68 8918 8927 1:CAS:528:DC%2BD1cXhtlSkur%2FF 18974136
    • (2008) Cancer Res , vol.68 , pp. 8918-8927
    • Taniguchi, H.1    Yoshida, T.2    Horinaka, M.3    Yasuda, T.4    Goda, A.E.5    Konishi, M.6    Wakada, M.7    Kataoka, K.8    Yoshikawa, T.9    Sakai, T.10
  • 85
    • 46749111467 scopus 로고    scopus 로고
    • Soy isoflavones, estrogen therapy, and breast cancer risk: Analysis and commentary
    • 18522734
    • MJ Messina CE Wood 2008 Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentary Nutr J 7 17 18522734
    • (2008) Nutr J , vol.7 , pp. 17
    • Messina, M.J.1    Wood, C.E.2
  • 86
    • 0036064773 scopus 로고    scopus 로고
    • Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGF-R inhibitor-enhanced TRAIL-induced apoptosis
    • 1:CAS:528:DC%2BD38XltFertLg%3D 12150980
    • SY Park DW Seol 2002 Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGF-R inhibitor-enhanced TRAIL-induced apoptosis Biochem Biophys Res Commun 295 515 518 1:CAS:528:DC%2BD38XltFertLg%3D 12150980
    • (2002) Biochem Biophys Res Commun , vol.295 , pp. 515-518
    • Park, S.Y.1    Seol, D.W.2
  • 87
    • 3042732298 scopus 로고    scopus 로고
    • The combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) and Genistein is effective in inhibiting pancreatic cancer growth
    • 1:CAS:528:DC%2BD2cXmtVSitLY%3D 15211111
    • F Nozawa A Itami M Saruc M Kim J Standop KS Picha KH Cowan PM Pour 2004 The combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) and Genistein is effective in inhibiting pancreatic cancer growth Pancreas 29 45 52 1:CAS:528:DC%2BD2cXmtVSitLY%3D 15211111
    • (2004) Pancreas , vol.29 , pp. 45-52
    • Nozawa, F.1    Itami, A.2    Saruc, M.3    Kim, M.4    Standop, J.5    Picha, K.S.6    Cowan, K.H.7    Pour, P.M.8
  • 89
    • 67349246450 scopus 로고    scopus 로고
    • Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells
    • 1:CAS:528:DC%2BD1MXmvF2itb0%3D 19497411
    • CY Jin C Park GY Kim SJ Lee WJ Kim YH Choi 2009 Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells Chem Biol Interact 180 143 150 1:CAS:528:DC%2BD1MXmvF2itb0%3D 19497411
    • (2009) Chem Biol Interact , vol.180 , pp. 143-150
    • Jin, C.Y.1    Park, C.2    Kim, G.Y.3    Lee, S.J.4    Kim, W.J.5    Choi, Y.H.6
  • 90
    • 70349332934 scopus 로고    scopus 로고
    • Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage
    • 1:CAS:528:DC%2BD1MXovVOhtr0%3D 19617819
    • CY Jin C Park SK Moon GY Kim TK Kwon SJ Lee WJ Kim YH Choi 2009 Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage Anticancer Drugs 20 713 722 1:CAS:528: DC%2BD1MXovVOhtr0%3D 19617819
    • (2009) Anticancer Drugs , vol.20 , pp. 713-722
    • Jin, C.Y.1    Park, C.2    Moon, S.K.3    Kim, G.Y.4    Kwon, T.K.5    Lee, S.J.6    Kim, W.J.7    Choi, Y.H.8
  • 91
    • 34648825655 scopus 로고    scopus 로고
    • Genistein sensitizes TRAIL-resistant human gastric adenocarcinoma AGS cells through activation of caspase-3
    • 1:CAS:528:DC%2BD2sXhtFSnt7vK 17689858
    • CY Jin C Park J Cheong BT Choi TH Lee JD Lee WH Lee GY Kim CH Ryu YH Choi 2007 Genistein sensitizes TRAIL-resistant human gastric adenocarcinoma AGS cells through activation of caspase-3 Cancer Lett 257 56 64 1:CAS:528: DC%2BD2sXhtFSnt7vK 17689858
    • (2007) Cancer Lett , vol.257 , pp. 56-64
    • Jin, C.Y.1    Park, C.2    Cheong, J.3    Choi, B.T.4    Lee, T.H.5    Lee, J.D.6    Lee, W.H.7    Kim, G.Y.8    Ryu, C.H.9    Choi, Y.H.10
  • 92
    • 61449099307 scopus 로고    scopus 로고
    • Genistein enhances proteasomal degradation of the short isoform of FLIP in malignant glioma cells and thereby augments TRAIL-mediated apoptosis
    • 1:CAS:528:DC%2BD1MXivVelu7k%3D 19356600
    • MD Siegelin Y Siegelin A Habel T Gaiser 2009 Genistein enhances proteasomal degradation of the short isoform of FLIP in malignant glioma cells and thereby augments TRAIL-mediated apoptosis Neurosci Lett 453 92 97 1:CAS:528:DC%2BD1MXivVelu7k%3D 19356600
    • (2009) Neurosci Lett , vol.453 , pp. 92-97
    • Siegelin, M.D.1    Siegelin, Y.2    Habel, A.3    Gaiser, T.4
  • 93
    • 63249129117 scopus 로고    scopus 로고
    • Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, Bcl-2
    • 1:CAS:528:DC%2BD1MXktFalt7o%3D 19429088
    • MD Siegelin T Gaiser A Habel Y Siegelin 2009 Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, Bcl-2 Neurosci Lett 454 223 228 1:CAS:528:DC%2BD1MXktFalt7o%3D 19429088
    • (2009) Neurosci Lett , vol.454 , pp. 223-228
    • Siegelin, M.D.1    Gaiser, T.2    Habel, A.3    Siegelin, Y.4
  • 94
    • 52649126205 scopus 로고    scopus 로고
    • Butein sensitizes human leukemia cells to apoptosis induced by tumor necrosis factor-related apoptosis inducing ligand (TRAIL)
    • 1:CAS:528:DC%2BD1cXhtFegtbfJ 18806962
    • N Kim 2008 Butein sensitizes human leukemia cells to apoptosis induced by tumor necrosis factor-related apoptosis inducing ligand (TRAIL) Arch Pharm Res 31 1179 1186 1:CAS:528:DC%2BD1cXhtFegtbfJ 18806962
    • (2008) Arch Pharm Res , vol.31 , pp. 1179-1186
    • Kim, N.1
  • 95
    • 67349188370 scopus 로고    scopus 로고
    • Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells
    • 1:CAS:528:DC%2BD1cXht1yntr3F 19568915
    • T Yoshida M Horinaka M Takara M Tsuchihashi N Mukai M Wakada T Sakai 2008 Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells Environ Health Prev Med 13 281 287 1:CAS:528:DC%2BD1cXht1yntr3F 19568915
    • (2008) Environ Health Prev Med , vol.13 , pp. 281-287
    • Yoshida, T.1    Horinaka, M.2    Takara, M.3    Tsuchihashi, M.4    Mukai, N.5    Wakada, M.6    Sakai, T.7
  • 96
    • 0042710263 scopus 로고    scopus 로고
    • Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells
    • 1:CAS:528:DC%2BD3sXhtlOit7s%3D 12533677
    • D Deeb YX Xu H Jiang X Gao N Janakiraman RA Chapman SC Gautam 2003 Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells Mol Cancer Ther 2 95 103 1:CAS:528:DC%2BD3sXhtlOit7s%3D 12533677
    • (2003) Mol Cancer Ther , vol.2 , pp. 95-103
    • Deeb, D.1    Xu, Y.X.2    Jiang, H.3    Gao, X.4    Janakiraman, N.5    Chapman, R.A.6    Gautam, S.C.7
  • 97
    • 1642576201 scopus 로고    scopus 로고
    • Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol
    • 1:CAS:528:DC%2BD2cXkslyrsA%3D%3D 14729643
    • S Fulda KM Debatin 2004 Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol Cancer Res 64 337 346 1:CAS:528:DC%2BD2cXkslyrsA%3D%3D 14729643
    • (2004) Cancer Res , vol.64 , pp. 337-346
    • Fulda, S.1    Debatin, K.M.2
  • 98
    • 14844312113 scopus 로고    scopus 로고
    • Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling
    • 1:CAS:528:DC%2BD2MXitF2isbw%3D 15763656
    • S Fulda KM Debatin 2005 Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling Eur J Cancer 41 786 798 1:CAS:528:DC%2BD2MXitF2isbw%3D 15763656
    • (2005) Eur J Cancer , vol.41 , pp. 786-798
    • Fulda, S.1    Debatin, K.M.2
  • 99
    • 10644246821 scopus 로고    scopus 로고
    • Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells
    • 1:CAS:528:DC%2BD2cXhtVWgtb%2FK 15480430
    • D Delmas C Rebe O Micheau A Athias P Gambert S Grazide G Laurent N Latruffe E Solary 2004 Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells Oncogene 23 8979 8986 1:CAS:528:DC%2BD2cXhtVWgtb%2FK 15480430
    • (2004) Oncogene , vol.23 , pp. 8979-8986
    • Delmas, D.1    Rebe, C.2    Micheau, O.3    Athias, A.4    Gambert, P.5    Grazide, S.6    Laurent, G.7    Latruffe, N.8    Solary, E.9
  • 100
    • 36448992018 scopus 로고    scopus 로고
    • Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4′, 5 tri-hydroxystilbene): Molecular mechanisms and therapeutic potential
    • 17718901
    • S Shankar Q Chen I Siddiqui K Sarva RK Srivastava 2007 Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4′, 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potential J Mol Signal 2 7 17718901
    • (2007) J Mol Signal , vol.2 , pp. 7
    • Shankar, S.1    Chen, Q.2    Siddiqui, I.3    Sarva, K.4    Srivastava, R.K.5
  • 101
    • 34648813877 scopus 로고    scopus 로고
    • Molecular mechanisms of resveratrol (3, 4, 5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells
    • 1:CAS:528:DC%2BD2sXhtVKrtrbN 17636462
    • S Shankar I Siddiqui RK Srivastava 2007 Molecular mechanisms of resveratrol (3, 4, 5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells Mol Cell Biochem 304 273 285 1:CAS:528:DC%2BD2sXhtVKrtrbN 17636462
    • (2007) Mol Cell Biochem , vol.304 , pp. 273-285
    • Shankar, S.1    Siddiqui, I.2    Srivastava, R.K.3
  • 102
    • 35648975568 scopus 로고    scopus 로고
    • Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms
    • 1:CAS:528:DC%2BD2sXhtlyrtL7L 17823925
    • C Gill SE Walsh C Morrissey JM Fitzpatrick RW Watson 2007 Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms Prostate 67 1641 1653 1:CAS:528:DC%2BD2sXhtlyrtL7L 17823925
    • (2007) Prostate , vol.67 , pp. 1641-1653
    • Gill, C.1    Walsh, S.E.2    Morrissey, C.3    Fitzpatrick, J.M.4    Watson, R.W.5
  • 103
    • 36749021164 scopus 로고    scopus 로고
    • Clusterin mediates TRAIL resistance in prostate tumor cells
    • 1:CAS:528:DC%2BD2sXhtlWkt7bI 18025278
    • DA Sallman X Chen B Zhong DL Gilvary J Zhou S Wei JY Djeu 2007 Clusterin mediates TRAIL resistance in prostate tumor cells Mol Cancer Ther 6 2938 2947 1:CAS:528:DC%2BD2sXhtlWkt7bI 18025278
    • (2007) Mol Cancer Ther , vol.6 , pp. 2938-2947
    • Sallman, D.A.1    Chen, X.2    Zhong, B.3    Gilvary, D.L.4    Zhou, J.5    Wei, S.6    Djeu, J.Y.7
  • 104
    • 39549088497 scopus 로고    scopus 로고
    • Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression
    • 1:CAS:528:DC%2BD1cXisVWjtbg%3D 18222423
    • VN Ivanov MA Partridge GE Johnson SX Huang H Zhou TK Hei 2008 Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression Exp Cell Res 314 1163 1176 1:CAS:528:DC%2BD1cXisVWjtbg%3D 18222423
    • (2008) Exp Cell Res , vol.314 , pp. 1163-1176
    • Ivanov, V.N.1    Partridge, M.A.2    Johnson, G.E.3    Huang, S.X.4    Zhou, H.5    Hei, T.K.6
  • 105
    • 34547786651 scopus 로고    scopus 로고
    • Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis
    • 1:CAS:528:DC%2BD2sXhtVaksrvO 17645780
    • T Yoshida T Shiraishi M Horinaka S Nakata T Yasuda AE Goda M Wakada Y Mizutani T Miki A Nishikawa T Sakai 2007 Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis Cancer Sci 98 1417 1423 1:CAS:528:DC%2BD2sXhtVaksrvO 17645780
    • (2007) Cancer Sci , vol.98 , pp. 1417-1423
    • Yoshida, T.1    Shiraishi, T.2    Horinaka, M.3    Nakata, S.4    Yasuda, T.5    Goda, A.E.6    Wakada, M.7    Mizutani, Y.8    Miki, T.9    Nishikawa, A.10    Sakai, T.11
  • 106
    • 51049115354 scopus 로고    scopus 로고
    • The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis
    • 1:CAS:528:DC%2BD1cXoslCnsrk%3D 18645030
    • SM Raja S Chen P Yue TM Acker B Lefkove JL Arbiser FR Khuri SY Sun 2008 The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis Mol Cancer Ther 7 2212 2223 1:CAS:528:DC%2BD1cXoslCnsrk%3D 18645030
    • (2008) Mol Cancer Ther , vol.7 , pp. 2212-2223
    • Raja, S.M.1    Chen, S.2    Yue, P.3    Acker, T.M.4    Lefkove, B.5    Arbiser, J.L.6    Khuri, F.R.7    Sun, S.Y.8
  • 107
    • 34548590339 scopus 로고    scopus 로고
    • Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin
    • 1:CAS:528:DC%2BD2sXpvFKju74%3D 17804742
    • YG Son EH Kim JY Kim SU Kim TK Kwon AR Yoon CO Yun KS Choi 2007 Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin Cancer Res 67 8274 8284 1:CAS:528:DC%2BD2sXpvFKju74%3D 17804742
    • (2007) Cancer Res , vol.67 , pp. 8274-8284
    • Son, Y.G.1    Kim, E.H.2    Kim, J.Y.3    Kim, S.U.4    Kwon, T.K.5    Yoon, A.R.6    Yun, C.O.7    Choi, K.S.8
  • 108
    • 55949095821 scopus 로고    scopus 로고
    • Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells
    • 1:CAS:528:DC%2BD1cXhtl2qtLbM 18755156
    • S Reuter S Eifes M Dicato BB Aggarwal M Diederich 2008 Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells Biochem Pharmacol 76 1340 1351 1:CAS:528: DC%2BD1cXhtl2qtLbM 18755156
    • (2008) Biochem Pharmacol , vol.76 , pp. 1340-1351
    • Reuter, S.1    Eifes, S.2    Dicato, M.3    Aggarwal, B.B.4    Diederich, M.5
  • 109
    • 38349011007 scopus 로고    scopus 로고
    • Curcumin: Preventive and therapeutic properties in laboratory studies and clinical trials
    • 1:CAS:528:DC%2BD1cXmt1yksQ%3D%3D 18370854
    • AS Strimpakos RA Sharma 2008 Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials Antioxid Redox Signal 10 511 545 1:CAS:528:DC%2BD1cXmt1yksQ%3D%3D 18370854
    • (2008) Antioxid Redox Signal , vol.10 , pp. 511-545
    • Strimpakos, A.S.1    Sharma, R.A.2
  • 110
    • 28444464762 scopus 로고    scopus 로고
    • Chemosensitization of hormone-refractory prostate cancer cells by curcumin to TRAIL-induced apoptosis
    • 1:CAS:528:DC%2BD2MXhtlWntr%2FE 16471035
    • DD Deeb H Jiang X Gao G Divine SA Dulchavsky SC Gautam 2005 Chemosensitization of hormone-refractory prostate cancer cells by curcumin to TRAIL-induced apoptosis J Exp Ther Oncol 5 81 91 1:CAS:528:DC%2BD2MXhtlWntr%2FE 16471035
    • (2005) J Exp Ther Oncol , vol.5 , pp. 81-91
    • Deeb, D.D.1    Jiang, H.2    Gao, X.3    Divine, G.4    Dulchavsky, S.A.5    Gautam, S.C.6
  • 111
    • 4444294803 scopus 로고    scopus 로고
    • Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation
    • 1:CAS:528:DC%2BD2cXls1amsr8%3D 15252141
    • D Deeb H Jiang X Gao MS Hafner H Wong G Divine RA Chapman SA Dulchavsky SC Gautam 2004 Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation Mol Cancer Ther 3 803 812 1:CAS:528:DC%2BD2cXls1amsr8%3D 15252141
    • (2004) Mol Cancer Ther , vol.3 , pp. 803-812
    • Deeb, D.1    Jiang, H.2    Gao, X.3    Hafner, M.S.4    Wong, H.5    Divine, G.6    Chapman, R.A.7    Dulchavsky, S.A.8    Gautam, S.C.9
  • 112
    • 34247229225 scopus 로고    scopus 로고
    • Curcumin [1, 7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3, 5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway
    • 1:CAS:528:DC%2BD2sXltFehur4%3D 17289836
    • D Deeb H Jiang X Gao S Al-Holou AL Danyluk SA Dulchavsky SC Gautam 2007 Curcumin [1, 7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3, 5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway J Pharmacol Exp Ther 321 616 625 1:CAS:528:DC%2BD2sXltFehur4%3D 17289836
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 616-625
    • Deeb, D.1    Jiang, H.2    Gao, X.3    Al-Holou, S.4    Danyluk, A.L.5    Dulchavsky, S.A.6    Gautam, S.C.7
  • 113
    • 61449198651 scopus 로고    scopus 로고
    • Therapeutic efficacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer
    • 1:CAS:528:DC%2BD1MXnslWhu74%3D 19192720
    • T Andrzejewski D Deeb X Gao A Danyluk AS Arbab SA Dulchavsky SC Gautam 2008 Therapeutic efficacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer Oncol Res 17 257 267 1:CAS:528: DC%2BD1MXnslWhu74%3D 19192720
    • (2008) Oncol Res , vol.17 , pp. 257-267
    • Andrzejewski, T.1    Deeb, D.2    Gao, X.3    Danyluk, A.4    Arbab, A.S.5    Dulchavsky, S.A.6    Gautam, S.C.7
  • 114
    • 36448981749 scopus 로고    scopus 로고
    • Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: Molecular mechanisms of apoptosis, migration and angiogenesis
    • 17916240
    • S Shankar Q Chen K Sarva I Siddiqui RK Srivastava 2007 Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: molecular mechanisms of apoptosis, migration and angiogenesis J Mol Signal 2 10 17916240
    • (2007) J Mol Signal , vol.2 , pp. 10
    • Shankar, S.1    Chen, Q.2    Sarva, K.3    Siddiqui, I.4    Srivastava, R.K.5
  • 115
    • 39749093675 scopus 로고    scopus 로고
    • Curcumin sensitizes TRAIL-resistant xenografts: Molecular mechanisms of apoptosis, metastasis and angiogenesis
    • 18226269
    • S Shankar S Ganapathy Q Chen RK Srivastava 2008 Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis Mol Cancer 7 16 18226269
    • (2008) Mol Cancer , vol.7 , pp. 16
    • Shankar, S.1    Ganapathy, S.2    Chen, Q.3    Srivastava, R.K.4
  • 116
    • 33749568038 scopus 로고    scopus 로고
    • Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation
    • 1:CAS:528:DC%2BD28XhtVOmu77J 16613838
    • EM Jung JW Park KS Choi HI Lee KS Lee TK Kwon 2006 Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation Carcinogenesis 27 2008 2017 1:CAS:528:DC%2BD28XhtVOmu77J 16613838
    • (2006) Carcinogenesis , vol.27 , pp. 2008-2017
    • Jung, E.M.1    Park, J.W.2    Choi, K.S.3    Lee, H.I.4    Lee, K.S.5    Kwon, T.K.6
  • 117
    • 27744609173 scopus 로고    scopus 로고
    • Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)
    • 1:CAS:528:DC%2BD2MXhtFCjt7vN 15987718
    • EM Jung JH Lim TJ Lee JW Park KS Choi TK Kwon 2005 Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5) Carcinogenesis 26 1905 1913 1:CAS:528:DC%2BD2MXhtFCjt7vN 15987718
    • (2005) Carcinogenesis , vol.26 , pp. 1905-1913
    • Jung, E.M.1    Lim, J.H.2    Lee, T.J.3    Park, J.W.4    Choi, K.S.5    Kwon, T.K.6
  • 118
    • 55749098119 scopus 로고    scopus 로고
    • Curcumin suppresses constitutive activation of nuclear factor-kappa B and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines
    • 1:CAS:528:DC%2BD1cXht1ensb%2FL 18852135
    • AR Hussain M Ahmed NA Al-Jomah AS Khan P Manogaran M Sultana J Abubaker LC Platanias KS Al-Kuraya S Uddin 2008 Curcumin suppresses constitutive activation of nuclear factor-kappa B and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines Mol Cancer Ther 7 3318 3329 1:CAS:528:DC%2BD1cXht1ensb%2FL 18852135
    • (2008) Mol Cancer Ther , vol.7 , pp. 3318-3329
    • Hussain, A.R.1    Ahmed, M.2    Al-Jomah, N.A.3    Khan, A.S.4    Manogaran, P.5    Sultana, M.6    Abubaker, J.7    Platanias, L.C.8    Al-Kuraya, K.S.9    Uddin, S.10
  • 119
    • 23044494635 scopus 로고    scopus 로고
    • Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria
    • 16416600
    • X Gao D Deeb H Jiang YB Liu SA Dulchavsky SC Gautam 2005 Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria J Exp Ther Oncol 5 39 48 16416600
    • (2005) J Exp Ther Oncol , vol.5 , pp. 39-48
    • Gao, X.1    Deeb, D.2    Jiang, H.3    Liu, Y.B.4    Dulchavsky, S.A.5    Gautam, S.C.6
  • 120
    • 34147138418 scopus 로고    scopus 로고
    • Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cancer cells
    • 1:CAS:528:DC%2BD2sXivV2nt78%3D 17363495
    • AM Kamat G Sethi BB Aggarwal 2007 Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cancer cells Mol Cancer Ther 6 1022 1030 1:CAS:528:DC%2BD2sXivV2nt78%3D 17363495
    • (2007) Mol Cancer Ther , vol.6 , pp. 1022-1030
    • Kamat, A.M.1    Sethi, G.2    Aggarwal, B.B.3
  • 121
    • 33947427176 scopus 로고    scopus 로고
    • Curcumin enhances Apo2L/TRAIL-induced apoptosis in chemoresistant ovarian cancer cells
    • DOI 10.1016/j.ygyno.2006.10.050, PII S0090825806008936
    • H Wahl L Tan K Griffith M Choi JR Liu 2007 Curcumin enhances Apo2L/TRAIL-induced apoptosis in chemoresistant ovarian cancer cells Gynecol Oncol 105 104 112 1:CAS:528:DC%2BD2sXjsVems7g%3D 17174384 (Pubitemid 46442871)
    • (2007) Gynecologic Oncology , vol.105 , Issue.1 , pp. 104-112
    • Wahl, H.1    Tan, L.2    Griffith, K.3    Choi, M.4    Liu, J.R.5
  • 122
    • 63149175753 scopus 로고    scopus 로고
    • A rice bran polyphenol, cycloartenyl ferulate, elicits apoptosis in human colorectal adenocarcinoma SW480 and sensitizes metastatic SW620 cells to TRAIL-induced apoptosis
    • 1:CAS:528:DC%2BD1MXktF2rsr8%3D 19426686
    • CK Kong WS Lam LC Chiu VE Ooi SS Sun YS Wong 2009 A rice bran polyphenol, cycloartenyl ferulate, elicits apoptosis in human colorectal adenocarcinoma SW480 and sensitizes metastatic SW620 cells to TRAIL-induced apoptosis Biochem Pharmacol 77 1487 1496 1:CAS:528:DC%2BD1MXktF2rsr8%3D 19426686
    • (2009) Biochem Pharmacol , vol.77 , pp. 1487-1496
    • Kong, C.K.1    Lam, W.S.2    Chiu, L.C.3    Ooi, V.E.4    Sun, S.S.5    Wong, Y.S.6
  • 123
    • 0031019034 scopus 로고    scopus 로고
    • Flavopiridol (L86-8275): Selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells
    • 1:CAS:528:DyaK2sXhsVOmtro%3D 9815683
    • M Drees WA Dengler T Roth H Labonte J Mayo L Malspeis M Grever EA Sausville HH Fiebig 1997 Flavopiridol (L86-8275): selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells Clin Cancer Res 3 273 279 1:CAS:528:DyaK2sXhsVOmtro%3D 9815683
    • (1997) Clin Cancer Res , vol.3 , pp. 273-279
    • Drees, M.1    Dengler, W.A.2    Roth, T.3    Labonte, H.4    Mayo, J.5    Malspeis, L.6    Grever, M.7    Sausville, E.A.8    Fiebig, H.H.9
  • 124
    • 3042536038 scopus 로고    scopus 로고
    • Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol
    • 1:CAS:528:DC%2BD2cXltFWls7o%3D 15217973
    • GI Shapiro 2004 Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol Clin Cancer Res 10 4270s 4275s 1:CAS:528:DC%2BD2cXltFWls7o%3D 15217973
    • (2004) Clin Cancer Res , vol.10
    • Shapiro, G.I.1
  • 125
    • 2442663096 scopus 로고    scopus 로고
    • Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells
    • 1:CAS:528:DC%2BD2cXktVWhsb4%3D 15150106
    • M Taniai A Grambihler H Higuchi N Werneburg SF Bronk DJ Farrugia SH Kaufmann GJ Gores 2004 Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells Cancer Res 64 3517 3524 1:CAS:528:DC%2BD2cXktVWhsb4%3D 15150106
    • (2004) Cancer Res , vol.64 , pp. 3517-3524
    • Taniai, M.1    Grambihler, A.2    Higuchi, H.3    Werneburg, N.4    Bronk, S.F.5    Farrugia, D.J.6    Kaufmann, S.H.7    Gores, G.J.8
  • 126
    • 8844228917 scopus 로고    scopus 로고
    • Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation
    • 1:CAS:528:DC%2BD2cXovVGitb8%3D 15385934
    • RR Rosato Y Dai JA Almenara SC Maggio S Grant 2004 Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation Leukemia 18 1780 1788 1:CAS:528:DC%2BD2cXovVGitb8%3D 15385934
    • (2004) Leukemia , vol.18 , pp. 1780-1788
    • Rosato, R.R.1    Dai, Y.2    Almenara, J.A.3    Maggio, S.C.4    Grant, S.5
  • 127
    • 34447509844 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor flavopiridol sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis
    • 1:CAS:528:DC%2BD28XotFKhtb4%3D 16820931
    • K Miyashita K Shiraki H Fuke T Inoue Y Yamanaka Y Yamaguchi N Yamamoto K Ito K Sugimoto T Nakano 2006 The cyclin-dependent kinase inhibitor flavopiridol sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis Int J Mol Med 18 249 256 1:CAS:528:DC%2BD28XotFKhtb4%3D 16820931
    • (2006) Int J Mol Med , vol.18 , pp. 249-256
    • Miyashita, K.1    Shiraki, K.2    Fuke, H.3    Inoue, T.4    Yamanaka, Y.5    Yamaguchi, Y.6    Yamamoto, N.7    Ito, K.8    Sugimoto, K.9    Nakano, T.10
  • 128
    • 33749004024 scopus 로고    scopus 로고
    • Flavopiridol induces cellular FLICE-inhibitory protein degradation by the proteasome and promotes TRAIL-induced early signaling and apoptosis in breast tumor cells
    • 1:CAS:528:DC%2BD28XovF2ht7s%3D 16951203
    • C Palacios R Yerbes A Lopez-Rivas 2006 Flavopiridol induces cellular FLICE-inhibitory protein degradation by the proteasome and promotes TRAIL-induced early signaling and apoptosis in breast tumor cells Cancer Res 66 8858 8869 1:CAS:528:DC%2BD28XovF2ht7s%3D 16951203
    • (2006) Cancer Res , vol.66 , pp. 8858-8869
    • Palacios, C.1    Yerbes, R.2    Lopez-Rivas, A.3
  • 129
    • 34250680223 scopus 로고    scopus 로고
    • Flavopiridol synergizes TRAIL cytotoxicity by downregulation of FLIPL
    • 1:CAS:528:DC%2BD2sXmsVOjsr8%3D 17187253
    • TE Fandy DD Ross SD Gore RK Srivastava 2007 Flavopiridol synergizes TRAIL cytotoxicity by downregulation of FLIPL Cancer Chemother Pharmacol 60 313 319 1:CAS:528:DC%2BD2sXmsVOjsr8%3D 17187253
    • (2007) Cancer Chemother Pharmacol , vol.60 , pp. 313-319
    • Fandy, T.E.1    Ross, D.D.2    Gore, S.D.3    Srivastava, R.K.4
  • 130
    • 0037311226 scopus 로고    scopus 로고
    • Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-alpha or TNF-related apoptosis-inducing ligand in human cancer cell lines
    • 1:CAS:528:DC%2BD3sXosVyisg%3D%3D 12566305
    • DM Kim SY Koo K Jeon MH Kim J Lee CY Hong S Jeong 2003 Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-alpha or TNF-related apoptosis-inducing ligand in human cancer cell lines Cancer Res 63 621 626 1:CAS:528:DC%2BD3sXosVyisg%3D%3D 12566305
    • (2003) Cancer Res , vol.63 , pp. 621-626
    • Kim, D.M.1    Koo, S.Y.2    Jeon, K.3    Kim, M.H.4    Lee, J.5    Hong, C.Y.6    Jeong, S.7
  • 131
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • 1:CAS:528:DC%2BD2sXhvFKrsro%3D 17309302
    • DJ Newman GM Cragg 2007 Natural products as sources of new drugs over the last 25 years J Nat Prod 70 461 477 1:CAS:528:DC%2BD2sXhvFKrsro%3D 17309302
    • (2007) J Nat Prod , vol.70 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 132
    • 28844492580 scopus 로고    scopus 로고
    • Chemosensitization and radiosensitization of tumors by plant polyphenols
    • 1:CAS:528:DC%2BD2MXhtlWht73M 16356126
    • AK Garg TA Buchholz BB Aggarwal 2005 Chemosensitization and radiosensitization of tumors by plant polyphenols Antioxid Redox Signal 7 1630 1647 1:CAS:528:DC%2BD2MXhtlWht73M 16356126
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1630-1647
    • Garg, A.K.1    Buchholz, T.A.2    Aggarwal, B.B.3
  • 133
    • 50249129735 scopus 로고    scopus 로고
    • Studies on search for bioactive natural products targeting TRAIL signaling leading to tumor cell apoptosis
    • 1:CAS:528:DC%2BD1cXhtV2qsLvN 18273883
    • M Ishibashi T Ohtsuki 2008 Studies on search for bioactive natural products targeting TRAIL signaling leading to tumor cell apoptosis Med Res Rev 28 688 714 1:CAS:528:DC%2BD1cXhtV2qsLvN 18273883
    • (2008) Med Res Rev , vol.28 , pp. 688-714
    • Ishibashi, M.1    Ohtsuki, T.2
  • 134
    • 61449220943 scopus 로고    scopus 로고
    • Ethanolic extract of propolis (EEP) enhances the apoptosis-inducing potential of TRAIL in cancer cells
    • 1:CAS:528:DC%2BD1MXisVWhtbc%3D 19223822
    • E Szliszka ZP Czuba M Domino B Mazur G Zydowicz W Krol 2009 Ethanolic extract of propolis (EEP) enhances the apoptosis-inducing potential of TRAIL in cancer cells Molecules 14 738 754 1:CAS:528:DC%2BD1MXisVWhtbc%3D 19223822
    • (2009) Molecules , vol.14 , pp. 738-754
    • Szliszka, E.1    Czuba, Z.P.2    Domino, M.3    Mazur, B.4    Zydowicz, G.5    Krol, W.6
  • 135
    • 77951215549 scopus 로고    scopus 로고
    • Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors
    • 1:CAS:528:DC%2BC3cXktFGlt7o%3D 20154087
    • B Sung B Park VR Yadav BB Aggarwal 2010 Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors J Biol Chem 285 11498 11507 1:CAS:528:DC%2BC3cXktFGlt7o%3D 20154087
    • (2010) J Biol Chem , vol.285 , pp. 11498-11507
    • Sung, B.1    Park, B.2    Yadav, V.R.3    Aggarwal, B.B.4
  • 136
    • 72449169529 scopus 로고    scopus 로고
    • Synergistic anti-cancer activity by the combination of TRAIL/APO-2L and celastrol
    • 1:CAS:528:DC%2BD1MXhsFCiu7rE
    • H Zhu WJ Ding R Wu QJ Weng JS Lou RJ Jin W Lu B Yang QJ He 2010 Synergistic anti-cancer activity by the combination of TRAIL/APO-2L and celastrol Cancer Investig 28 23 32 1:CAS:528:DC%2BD1MXhsFCiu7rE
    • (2010) Cancer Investig , vol.28 , pp. 23-32
    • Zhu, H.1    Ding, W.J.2    Wu, R.3    Weng, Q.J.4    Lou, J.S.5    Jin, R.J.6    Lu, W.7    Yang, B.8    He, Q.J.9
  • 137
    • 59149087882 scopus 로고    scopus 로고
    • Suppression of cFLIP by lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells
    • 1:CAS:528:DC%2BD1MXhtFOlu78%3D 19176377
    • I Murtaza M Saleem VM Adhami BB Hafeez H Mukhtar 2009 Suppression of cFLIP by lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells Cancer Res 69 1156 1165 1:CAS:528:DC%2BD1MXhtFOlu78%3D 19176377
    • (2009) Cancer Res , vol.69 , pp. 1156-1165
    • Murtaza, I.1    Saleem, M.2    Adhami, V.M.3    Hafeez, B.B.4    Mukhtar, H.5
  • 138
    • 0033863355 scopus 로고    scopus 로고
    • Dietary intake and bioavailability of polyphenols
    • 1:CAS:528:DC%2BD3cXltl2gsLw%3D 10917926
    • A Scalbert G Williamson 2000 Dietary intake and bioavailability of polyphenols J Nutr 130 2073S 2085S 1:CAS:528:DC%2BD3cXltl2gsLw%3D 10917926
    • (2000) J Nutr , vol.130
    • Scalbert, A.1    Williamson, G.2
  • 139
  • 140
    • 74049161626 scopus 로고    scopus 로고
    • Resveratrol-loaded calcium-pectinate beads: Effects of formulation parameters on drug release and bead characteristics
    • 1:CAS:528:DC%2BD1MXhsF2jsLvF 19653272
    • S Das KY Ng 2010 Resveratrol-loaded calcium-pectinate beads: effects of formulation parameters on drug release and bead characteristics J Pharm Sci 99 840 860 1:CAS:528:DC%2BD1MXhsF2jsLvF 19653272
    • (2010) J Pharm Sci , vol.99 , pp. 840-860
    • Das, S.1    Ng, K.Y.2
  • 141
    • 66149107051 scopus 로고    scopus 로고
    • Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice
    • 1:CAS:528:DC%2BD1MXmslCguro%3D 19326431
    • NK Narayanan D Nargi C Randolph BA Narayanan 2009 Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice Int J Cancer 125 1 8 1:CAS:528:DC%2BD1MXmslCguro%3D 19326431
    • (2009) Int J Cancer , vol.125 , pp. 1-8
    • Narayanan, N.K.1    Nargi, D.2    Randolph, C.3    Narayanan, B.A.4
  • 142
    • 33646491901 scopus 로고    scopus 로고
    • Effect of liposome encapsulation of tea catechins on their accumulation in basal cell carcinomas
    • 1:CAS:528:DC%2BD28XjvVagur4%3D 16423506
    • JY Fang WR Lee SC Shen YL Huang 2006 Effect of liposome encapsulation of tea catechins on their accumulation in basal cell carcinomas J Dermatol Sci 42 101 109 1:CAS:528:DC%2BD28XjvVagur4%3D 16423506
    • (2006) J Dermatol Sci , vol.42 , pp. 101-109
    • Fang, J.Y.1    Lee, W.R.2    Shen, S.C.3    Huang, Y.L.4
  • 144
    • 44349192682 scopus 로고    scopus 로고
    • Delivery of resveratrol, a red wine polyphenol, from solutions and hydrogels via the skin
    • 1:CAS:528:DC%2BD1cXotF2mt7c%3D 18451526
    • CF Hung YK Lin ZR Huang JY Fang 2008 Delivery of resveratrol, a red wine polyphenol, from solutions and hydrogels via the skin Biol Pharm Bull 31 955 962 1:CAS:528:DC%2BD1cXotF2mt7c%3D 18451526
    • (2008) Biol Pharm Bull , vol.31 , pp. 955-962
    • Hung, C.F.1    Lin, Y.K.2    Huang, Z.R.3    Fang, J.Y.4


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