-
1
-
-
49049086338
-
Ligand-based targeting of apoptosis in cancer: The potential of recombinant human apoptosis ligand 2/tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL)
-
1:CAS:528:DC%2BD1cXpvVWmtbw%3D 18640940
-
A Ashkenazi P Holland SG Eckhardt 2008 Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL) J Clin Oncol 26 3621 3630 1:CAS:528:DC%2BD1cXpvVWmtbw%3D 18640940
-
(2008)
J Clin Oncol
, vol.26
, pp. 3621-3630
-
-
Ashkenazi, A.1
Holland, P.2
Eckhardt, S.G.3
-
2
-
-
76349085626
-
Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer
-
1:CAS:528:DC%2BC3cXhsVSrs7s%3D 20068564
-
T Trarbach M Moehler V Heinemann CH Kohne M Przyborek C Schulz V Sneller G Gallant S Kanzler 2010 Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer Br J Cancer 102 506 512 1:CAS:528:DC%2BC3cXhsVSrs7s%3D 20068564
-
(2010)
Br J Cancer
, vol.102
, pp. 506-512
-
-
Trarbach, T.1
Moehler, M.2
Heinemann, V.3
Kohne, C.H.4
Przyborek, M.5
Schulz, C.6
Sneller, V.7
Gallant, G.8
Kanzler, S.9
-
3
-
-
62449166171
-
Is TRAIL the holy grail of cancer therapy?
-
1:CAS:528:DC%2BD1MXivFSns7Y%3D 19194800
-
T Newsom-Davis S Prieske H Walczak 2009 Is TRAIL the holy grail of cancer therapy? Apoptosis 14 607 623 1:CAS:528:DC%2BD1MXivFSns7Y%3D 19194800
-
(2009)
Apoptosis
, vol.14
, pp. 607-623
-
-
Newsom-Davis, T.1
Prieske, S.2
Walczak, H.3
-
4
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
1:CAS:528:DyaK1MXkslSmsbw%3D 10411544
-
A Ashkenazi RC Pai S Fong S Leung DA Lawrence SA Marsters C Blackie L Chang AE McMurtrey A Hebert L DeForge IL Koumenis D Lewis L Harris J Bussiere H Koeppen Z Shahrokh RH Schwall 1999 Safety and antitumor activity of recombinant soluble Apo2 ligand J Clin Investig 104 155 162 1:CAS:528:DyaK1MXkslSmsbw%3D 10411544
-
(1999)
J Clin Investig
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
Blackie, C.7
Chang, L.8
McMurtrey, A.E.9
Hebert, A.10
Deforge, L.11
Koumenis, I.L.12
Lewis, D.13
Harris, L.14
Bussiere, J.15
Koeppen, H.16
Shahrokh, Z.17
Schwall, R.H.18
-
5
-
-
0034812659
-
Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: Characterization of in vivo efficacy, pharmacokinetics, and safety
-
1:CAS:528:DC%2BD3MXntFWltrw%3D 11561060
-
SK Kelley LA Harris D Xie L Deforge K Totpal J Bussiere JA Fox 2001 Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: characterization of in vivo efficacy, pharmacokinetics, and safety J Pharmacol Exp Ther 299 31 38 1:CAS:528:DC%2BD3MXntFWltrw%3D 11561060
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 31-38
-
-
Kelley, S.K.1
Harris, L.A.2
Xie, D.3
Deforge, L.4
Totpal, K.5
Bussiere, J.6
Fox, J.A.7
-
6
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
-
1:CAS:528:DC%2BD3MXis1ymtb0%3D 11283636
-
D Lawrence Z Shahrokh S Marsters K Achilles D Shih B Mounho K Hillan K Totpal L DeForge P Schow J Hooley S Sherwood R Pai S Leung L Khan B Gliniak J Bussiere CA Smith SS Strom S Kelley JA Fox D Thomas A Ashkenazi 2001 Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions Nat Med 7 383 385 1:CAS:528:DC%2BD3MXis1ymtb0%3D 11283636
-
(2001)
Nat Med
, vol.7
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
Achilles, K.4
Shih, D.5
Mounho, B.6
Hillan, K.7
Totpal, K.8
Deforge, L.9
Schow, P.10
Hooley, J.11
Sherwood, S.12
Pai, R.13
Leung, S.14
Khan, L.15
Gliniak, B.16
Bussiere, J.17
Smith, C.A.18
Strom, S.S.19
Kelley, S.20
Fox, J.A.21
Thomas, D.22
Ashkenazi, A.23
more..
-
7
-
-
33745854287
-
The role of the TRAIL/TRAIL receptors system in hematopoiesis and endothelial cell biology
-
1:CAS:528:DC%2BD28XntFSgsbw%3D 16750931
-
G Zauli P Secchiero 2006 The role of the TRAIL/TRAIL receptors system in hematopoiesis and endothelial cell biology Cytokine Growth Factor Rev 17 245 257 1:CAS:528:DC%2BD28XntFSgsbw%3D 16750931
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 245-257
-
-
Zauli, G.1
Secchiero, P.2
-
8
-
-
33746493900
-
The molecular biology of TRAIL-mediated signaling and its potential therapeutic exploitation in hematopoietic malignancies
-
1:CAS:528:DC%2BD28XnslOksr0%3D 16918339
-
S Boehrer D Nowak D Hoelzer PS Mitrou KU Chow 2006 The molecular biology of TRAIL-mediated signaling and its potential therapeutic exploitation in hematopoietic malignancies Curr Med Chem 13 2091 2100 1:CAS:528: DC%2BD28XnslOksr0%3D 16918339
-
(2006)
Curr Med Chem
, vol.13
, pp. 2091-2100
-
-
Boehrer, S.1
Nowak, D.2
Hoelzer, D.3
Mitrou, P.S.4
Chow, K.U.5
-
9
-
-
33645091240
-
TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer
-
1:CAS:528:DC%2BD28Xhs1CqsLk%3D 16405656
-
E Cretney A Shanker H Yagita MJ Smyth TJ Sayers 2006 TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer Immunol Cell Biol 84 87 98 1:CAS:528:DC%2BD28Xhs1CqsLk%3D 16405656
-
(2006)
Immunol Cell Biol
, vol.84
, pp. 87-98
-
-
Cretney, E.1
Shanker, A.2
Yagita, H.3
Smyth, M.J.4
Sayers, T.J.5
-
10
-
-
10344260656
-
TRAIL-R as a negative regulator of innate immune cell responses
-
1:CAS:528:DC%2BD2MXjvFGjuw%3D%3D 15589175
-
GE Diehl HH Yue K Hsieh AA Kuang M Ho LA Morici LL Lenz D Cado LW Riley A Winoto 2004 TRAIL-R as a negative regulator of innate immune cell responses Immunity 21 877 889 1:CAS:528:DC%2BD2MXjvFGjuw%3D%3D 15589175
-
(2004)
Immunity
, vol.21
, pp. 877-889
-
-
Diehl, G.E.1
Yue, H.H.2
Hsieh, K.3
Kuang, A.A.4
Ho, M.5
Morici, L.A.6
Lenz, L.L.7
Cado, D.8
Riley, L.W.9
Winoto, A.10
-
11
-
-
14544288632
-
CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death
-
1:CAS:528:DC%2BD2MXhslClsLc%3D 15744305
-
EM Janssen NM Droin EE Lemmens MJ Pinkoski SJ Bensinger BD Ehst TS Griffith DR Green SP Schoenberger 2005 CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death Nature 434 88 93 1:CAS:528:DC%2BD2MXhslClsLc%3D 15744305
-
(2005)
Nature
, vol.434
, pp. 88-93
-
-
Janssen, E.M.1
Droin, N.M.2
Lemmens, E.E.3
Pinkoski, M.J.4
Bensinger, S.J.5
Ehst, B.D.6
Griffith, T.S.7
Green, D.R.8
Schoenberger, S.P.9
-
12
-
-
0036467427
-
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
-
1:CAS:528:DC%2BD38XpsFektw%3D%3D 11801676
-
E Cretney K Takeda H Yagita M Glaccum JJ Peschon MJ Smyth 2002 Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice J Immunol 168 1356 1361 1:CAS:528:DC%2BD38XpsFektw%3D%3D 11801676
-
(2002)
J Immunol
, vol.168
, pp. 1356-1361
-
-
Cretney, E.1
Takeda, K.2
Yagita, H.3
Glaccum, M.4
Peschon, J.J.5
Smyth, M.J.6
-
13
-
-
0036914180
-
T cells require TRAIL for optimal graft-versus-tumor activity
-
1:CAS:528:DC%2BD38XptVSgsbk%3D 12426560
-
C Schmaltz O Alpdogan BJ Kappel SJ Muriglan JA Rotolo J Ongchin LM Willis AS Greenberg JM Eng JM Crawford GF Murphy H Yagita H Walczak JJ Peschon MR van den Brink 2002 T cells require TRAIL for optimal graft-versus-tumor activity Nat Med 8 1433 1437 1:CAS:528:DC%2BD38XptVSgsbk%3D 12426560
-
(2002)
Nat Med
, vol.8
, pp. 1433-1437
-
-
Schmaltz, C.1
Alpdogan, O.2
Kappel, B.J.3
Muriglan, S.J.4
Rotolo, J.A.5
Ongchin, J.6
Willis, L.M.7
Greenberg, A.S.8
Eng, J.M.9
Crawford, J.M.10
Murphy, G.F.11
Yagita, H.12
Walczak, H.13
Peschon, J.J.14
Van Den Brink, M.R.15
-
14
-
-
51049122396
-
Metastasis suppressor function of tumor necrosis factor-related apoptosis-inducing ligand-R in mice: Implications for TRAIL-based therapy in humans?
-
1:CAS:528:DC%2BD1cXpt1Sqtrk%3D 18676822
-
A Grosse-Wilde CJ Kemp 2008 Metastasis suppressor function of tumor necrosis factor-related apoptosis-inducing ligand-R in mice: implications for TRAIL-based therapy in humans? Cancer Res 68 6035 6037 1:CAS:528: DC%2BD1cXpt1Sqtrk%3D 18676822
-
(2008)
Cancer Res
, vol.68
, pp. 6035-6037
-
-
Grosse-Wilde, A.1
Kemp, C.J.2
-
15
-
-
58149171658
-
Conjunctival sac fluid contains elevated levels of soluble TRAIL: Implications for the anti-tumoral surveillance of the anterior surface of the eye
-
1:CAS:528:DC%2BD1cXhsFahsbfE 18780288
-
P Secchiero G Lamberti F Corallini E Melloni C Guarnotta A Sebastiani G Zauli 2009 Conjunctival sac fluid contains elevated levels of soluble TRAIL: implications for the anti-tumoral surveillance of the anterior surface of the eye J Cell Physiol 218 199 204 1:CAS:528:DC%2BD1cXhsFahsbfE 18780288
-
(2009)
J Cell Physiol
, vol.218
, pp. 199-204
-
-
Secchiero, P.1
Lamberti, G.2
Corallini, F.3
Melloni, E.4
Guarnotta, C.5
Sebastiani, A.6
Zauli, G.7
-
16
-
-
77953242476
-
Potential role of soluble TRAIL in epithelial injury in children with severe RSV infection
-
doi: 10.1165/rcmb.2009-0100OC
-
Bem RA, Bos AP, Wosten-van Asperen RM, Bruijn M, Lutter R, Sprick MR, van Woensel JB (2009) Potential role of soluble TRAIL in epithelial injury in children with severe RSV infection. Am J Respir Cell Mol Biol. doi: 10.1165/rcmb.2009-0100OC
-
(2009)
Am J Respir Cell Mol Biol
-
-
Bem, R.A.1
Bos, A.P.2
Wosten-Van Asperen, R.M.3
Bruijn, M.4
Lutter, R.5
Sprick, M.R.6
Van Woensel, J.B.7
-
17
-
-
0036899204
-
Detection of soluble TRAIL in HBV infected patients and its clinical implications
-
1:CAS:528:DC%2BD38XpvVSnsrk%3D 12439929
-
LH Han WS Sun CH Ma LN Zhang SX Liu Q Zhang LF Gao YH Chen 2002 Detection of soluble TRAIL in HBV infected patients and its clinical implications World J Gastroenterol 8 1077 1080 1:CAS:528:DC%2BD38XpvVSnsrk%3D 12439929
-
(2002)
World J Gastroenterol
, vol.8
, pp. 1077-1080
-
-
Han, L.H.1
Sun, W.S.2
Ma, C.H.3
Zhang, L.N.4
Liu, S.X.5
Zhang, Q.6
Gao, L.F.7
Chen, Y.H.8
-
18
-
-
0032550366
-
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
-
1:CAS:528:DyaK1cXis1Cru7o%3D 9547332
-
P Schneider N Holler JL Bodmer M Hahne K Frei A Fontana J Tschopp 1998 Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity J Exp Med 187 1205 1213 1:CAS:528:DyaK1cXis1Cru7o%3D 9547332
-
(1998)
J Exp Med
, vol.187
, pp. 1205-1213
-
-
Schneider, P.1
Holler, N.2
Bodmer, J.L.3
Hahne, M.4
Frei, K.5
Fontana, A.6
Tschopp, J.7
-
20
-
-
0031406386
-
Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway
-
1:CAS:528:DyaK1cXjsFWrsQ%3D%3D 9430227
-
PM Chaudhary M Eby A Jasmin A Bookwalter J Murray L Hood 1997 Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway Immunity 7 821 830 1:CAS:528:DyaK1cXjsFWrsQ%3D%3D 9430227
-
(1997)
Immunity
, vol.7
, pp. 821-830
-
-
Chaudhary, P.M.1
Eby, M.2
Jasmin, A.3
Bookwalter, A.4
Murray, J.5
Hood, L.6
-
21
-
-
0030880548
-
TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL
-
1:CAS:528:DyaK2sXmsVGlsLo%3D 9311998
-
H Walczak MA Degli-Esposti RS Johnson PJ Smolak JY Waugh N Boiani MS Timour MJ Gerhart KA Schooley CA Smith RG Goodwin CT Rauch 1997 TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL EMBO J 16 5386 5397 1:CAS:528:DyaK2sXmsVGlsLo%3D 9311998
-
(1997)
EMBO J
, vol.16
, pp. 5386-5397
-
-
Walczak, H.1
Degli-Esposti, M.A.2
Johnson, R.S.3
Smolak, P.J.4
Waugh, J.Y.5
Boiani, N.6
Timour, M.S.7
Gerhart, M.J.8
Schooley, K.A.9
Smith, C.A.10
Goodwin, R.G.11
Rauch, C.T.12
-
23
-
-
0030770614
-
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL
-
1:CAS:528:DyaK2sXms1Cqsr4%3D 9325248
-
M MacFarlane M Ahmad SM Srinivasula T Fernandes-Alnemri GM Cohen ES Alnemri 1997 Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL J Biol Chem 272 25417 25420 1:CAS:528:DyaK2sXms1Cqsr4%3D 9325248
-
(1997)
J Biol Chem
, vol.272
, pp. 25417-25420
-
-
MacFarlane, M.1
Ahmad, M.2
Srinivasula, S.M.3
Fernandes-Alnemri, T.4
Cohen, G.M.5
Alnemri, E.S.6
-
24
-
-
0030869432
-
Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
-
1:CAS:528:DyaK2sXmsFaqs70%3D 9314565
-
MA Degli-Esposti PJ Smolak H Walczak J Waugh CP Huang RF DuBose RG Goodwin CA Smith 1997 Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family J Exp Med 186 1165 1170 1:CAS:528:DyaK2sXmsFaqs70%3D 9314565
-
(1997)
J Exp Med
, vol.186
, pp. 1165-1170
-
-
Degli-Esposti, M.A.1
Smolak, P.J.2
Walczak, H.3
Waugh, J.4
Huang, C.P.5
Dubose, R.F.6
Goodwin, R.G.7
Smith, C.A.8
-
25
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
-
1:CAS:528:DyaK2sXlt1eksro%3D 9242610
-
G Pan J Ni YF Wei G Yu R Gentz VM Dixit 1997 An antagonist decoy receptor and a death domain-containing receptor for TRAIL Science 277 815 818 1:CAS:528:DyaK2sXlt1eksro%3D 9242610
-
(1997)
Science
, vol.277
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.F.3
Yu, G.4
Gentz, R.5
Dixit, V.M.6
-
26
-
-
0031414749
-
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
-
1:CAS:528:DyaK1cXjsFWgtQ%3D%3D 9430226
-
MA Degli-Esposti WC Dougall PJ Smolak JY Waugh CA Smith RG Goodwin 1997 The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain Immunity 7 813 820 1:CAS:528:DyaK1cXjsFWgtQ%3D%3D 9430226
-
(1997)
Immunity
, vol.7
, pp. 813-820
-
-
Degli-Esposti, M.A.1
Dougall, W.C.2
Smolak, P.J.3
Waugh, J.Y.4
Smith, C.A.5
Goodwin, R.G.6
-
27
-
-
13144265771
-
A novel receptor for Apo2L/TRAIL contains a truncated death domain
-
1:CAS:528:DyaK2sXotFSls7o%3D 9382840
-
SA Marsters JP Sheridan RM Pitti A Huang M Skubatch D Baldwin J Yuan A Gurney AD Goddard P Godowski A Ashkenazi 1997 A novel receptor for Apo2L/TRAIL contains a truncated death domain Curr Biol 7 1003 1006 1:CAS:528: DyaK2sXotFSls7o%3D 9382840
-
(1997)
Curr Biol
, vol.7
, pp. 1003-1006
-
-
Marsters, S.A.1
Sheridan, J.P.2
Pitti, R.M.3
Huang, A.4
Skubatch, M.5
Baldwin, D.6
Yuan, J.7
Gurney, A.8
Goddard, A.D.9
Godowski, P.10
Ashkenazi, A.11
-
28
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
1:CAS:528:DyaK1cXit1Git74%3D 9501089
-
C Scaffidi S Fulda A Srinivasan C Friesen F Li KJ Tomaselli KM Debatin PH Krammer ME Peter 1998 Two CD95 (APO-1/Fas) signaling pathways EMBO J 17 1675 1687 1:CAS:528:DyaK1cXit1Git74%3D 9501089
-
(1998)
EMBO J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.M.7
Krammer, P.H.8
Peter, M.E.9
-
29
-
-
0036859738
-
Defining characteristics of types i and II apoptotic cells in response to TRAIL
-
12407450
-
N Ozoren WS El-Deiry 2002 Defining characteristics of types I and II apoptotic cells in response to TRAIL Neoplasia 4 551 557 12407450
-
(2002)
Neoplasia
, vol.4
, pp. 551-557
-
-
Ozoren, N.1
El-Deiry, W.S.2
-
30
-
-
0036131142
-
Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
-
1:CAS:528:DC%2BD38Xit1Cisb8%3D 11875499
-
H LeBlanc D Lawrence E Varfolomeev K Totpal J Morlan P Schow S Fong R Schwall D Sinicropi A Ashkenazi 2002 Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax Nat Med 8 274 281 1:CAS:528:DC%2BD38Xit1Cisb8%3D 11875499
-
(2002)
Nat Med
, vol.8
, pp. 274-281
-
-
Leblanc, H.1
Lawrence, D.2
Varfolomeev, E.3
Totpal, K.4
Morlan, J.5
Schow, P.6
Fong, S.7
Schwall, R.8
Sinicropi, D.9
Ashkenazi, A.10
-
31
-
-
0033529534
-
Differential modulation of apoptosis sensitivity in CD95 type i and type II cells
-
1:CAS:528:DyaK1MXlt1CnsLg%3D 10428830
-
C Scaffidi I Schmitz J Zha SJ Korsmeyer PH Krammer ME Peter 1999 Differential modulation of apoptosis sensitivity in CD95 type I and type II cells J Biol Chem 274 22532 22538 1:CAS:528:DyaK1MXlt1CnsLg%3D 10428830
-
(1999)
J Biol Chem
, vol.274
, pp. 22532-22538
-
-
Scaffidi, C.1
Schmitz, I.2
Zha, J.3
Korsmeyer, S.J.4
Krammer, P.H.5
Peter, M.E.6
-
32
-
-
3042743700
-
Regulation of TRAIL-induced apoptosis by ectopic expression of antiapoptotic factors
-
1:CAS:528:DC%2BD2cXltlKgtb8%3D 15110190
-
BB Aggarwal U Bhardwaj Y Takada 2004 Regulation of TRAIL-induced apoptosis by ectopic expression of antiapoptotic factors Vitam Horm 67 453 483 1:CAS:528:DC%2BD2cXltlKgtb8%3D 15110190
-
(2004)
Vitam Horm
, vol.67
, pp. 453-483
-
-
Aggarwal, B.B.1
Bhardwaj, U.2
Takada, Y.3
-
34
-
-
4544253226
-
Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity
-
1:CAS:528:DC%2BD2cXnvVaktLw%3D 15367674
-
MS Ricci Z Jin M Dews D Yu A Thomas-Tikhonenko DT Dicker WS El-Deiry 2004 Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity Mol Cell Biol 24 8541 8555 1:CAS:528:DC%2BD2cXnvVaktLw%3D 15367674
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8541-8555
-
-
Ricci, M.S.1
Jin, Z.2
Dews, M.3
Yu, D.4
Thomas-Tikhonenko, A.5
Dicker, D.T.6
El-Deiry, W.S.7
-
35
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
1:CAS:528:DC%2BD3sXlvFCgu7Y%3D 12887920
-
O Micheau J Tschopp 2003 Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes Cell 114 181 190 1:CAS:528: DC%2BD3sXlvFCgu7Y%3D 12887920
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
36
-
-
33749164762
-
Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2
-
1:CAS:528:DC%2BD28XhtVCltbnK 16980609
-
D Merino N Lalaoui A Morizot P Schneider E Solary O Micheau 2006 Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2 Mol Cell Biol 26 7046 7055 1:CAS:528:DC%2BD28XhtVCltbnK 16980609
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7046-7055
-
-
Merino, D.1
Lalaoui, N.2
Morizot, A.3
Schneider, P.4
Solary, E.5
Micheau, O.6
-
37
-
-
62749084512
-
Palmitoylation of the TRAIL receptor DR4 confers an efficient TRAIL-induced cell death signalling
-
1:CAS:528:DC%2BD1MXjtVShu7k%3D 19090789 (2 p following 192)
-
A Rossin M Derouet F Abdel-Sater AO Hueber 2009 Palmitoylation of the TRAIL receptor DR4 confers an efficient TRAIL-induced cell death signalling Biochem J 419 185 192 1:CAS:528:DC%2BD1MXjtVShu7k%3D 19090789 (2 p following 192)
-
(2009)
Biochem J
, vol.419
, pp. 185-192
-
-
Rossin, A.1
Derouet, M.2
Abdel-Sater, F.3
Hueber, A.O.4
-
38
-
-
34948894931
-
Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL
-
1:CAS:528:DC%2BD2sXhtVSgtrvO 17767167
-
KW Wagner EA Punnoose T Januario DA Lawrence RM Pitti K Lancaster D Lee M von Goetz SF Yee K Totpal L Huw V Katta G Cavet SG Hymowitz L Amler A Ashkenazi 2007 Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL Nat Med 13 1070 1077 1:CAS:528: DC%2BD2sXhtVSgtrvO 17767167
-
(2007)
Nat Med
, vol.13
, pp. 1070-1077
-
-
Wagner, K.W.1
Punnoose, E.A.2
Januario, T.3
Lawrence, D.A.4
Pitti, R.M.5
Lancaster, K.6
Lee, D.7
Von Goetz, M.8
Yee, S.F.9
Totpal, K.10
Huw, L.11
Katta, V.12
Cavet, G.13
Hymowitz, S.G.14
Amler, L.15
Ashkenazi, A.16
-
39
-
-
38449118214
-
Glycosylation modulates TRAIL-R1/death receptor 4 protein: Different regulations of two pro-apoptotic receptors for TRAIL by tunicamycin
-
1:CAS:528:DC%2BD2sXhtlKhsr%2FK 17914579
-
T Yoshida T Shiraishi M Horinaka M Wakada T Sakai 2007 Glycosylation modulates TRAIL-R1/death receptor 4 protein: different regulations of two pro-apoptotic receptors for TRAIL by tunicamycin Oncol Rep 18 1239 1242 1:CAS:528:DC%2BD2sXhtlKhsr%2FK 17914579
-
(2007)
Oncol Rep
, vol.18
, pp. 1239-1242
-
-
Yoshida, T.1
Shiraishi, T.2
Horinaka, M.3
Wakada, M.4
Sakai, T.5
-
40
-
-
42749092258
-
TRAIL receptor-targeted therapeutics: Resistance mechanisms and strategies to avoid them
-
1:CAS:528:DC%2BD1cXlslWqtbY%3D 18374623
-
A Thorburn K Behbakht H Ford 2008 TRAIL receptor-targeted therapeutics: resistance mechanisms and strategies to avoid them Drug Resist Updat 11 17 24 1:CAS:528:DC%2BD1cXlslWqtbY%3D 18374623
-
(2008)
Drug Resist Updat
, vol.11
, pp. 17-24
-
-
Thorburn, A.1
Behbakht, K.2
Ford, H.3
-
41
-
-
14644437742
-
Mechanisms of resistance to TRAIL-induced apoptosis in cancer
-
1:CAS:528:DC%2BD2MXhtlahsLc%3D 15550937
-
L Zhang B Fang 2005 Mechanisms of resistance to TRAIL-induced apoptosis in cancer Cancer Gene Ther 12 228 237 1:CAS:528:DC%2BD2MXhtlahsLc%3D 15550937
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 228-237
-
-
Zhang, L.1
Fang, B.2
-
42
-
-
3042665524
-
Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation
-
1:CAS:528:DC%2BD2cXkvFWlsro%3D 15205314
-
M Kim SY Park HS Pai TH Kim TR Billiar DW Seol 2004 Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation Cancer Res 64 4078 4081 1:CAS:528: DC%2BD2cXkvFWlsro%3D 15205314
-
(2004)
Cancer Res
, vol.64
, pp. 4078-4081
-
-
Kim, M.1
Park, S.Y.2
Pai, H.S.3
Kim, T.H.4
Billiar, T.R.5
Seol, D.W.6
-
43
-
-
64049103030
-
TRAIL receptor signalling and modulation: Are we on the right TRAIL?
-
1:CAS:528:DC%2BD1MXksVantrY%3D 19117685
-
D Mahalingam E Szegezdi M Keane S Jong A Samali 2009 TRAIL receptor signalling and modulation: are we on the right TRAIL? Cancer Treat Rev 35 280 288 1:CAS:528:DC%2BD1MXksVantrY%3D 19117685
-
(2009)
Cancer Treat Rev
, vol.35
, pp. 280-288
-
-
Mahalingam, D.1
Szegezdi, E.2
Keane, M.3
Jong, S.4
Samali, A.5
-
44
-
-
38949127219
-
Polyphenols, dietary sources and bioavailability
-
18209268
-
M D'Archivio C Filesi R Di Benedetto R Gargiulo C Giovannini R Masella 2007 Polyphenols, dietary sources and bioavailability Ann Ist Super Sanita 43 348 361 18209268
-
(2007)
Ann Ist Super Sanita
, vol.43
, pp. 348-361
-
-
D'Archivio, M.1
Filesi, C.2
Di Benedetto, R.3
Gargiulo, R.4
Giovannini, C.5
Masella, R.6
-
45
-
-
48649095089
-
Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways
-
1:CAS:528:DC%2BD1cXms1egt7k%3D 18435439
-
S Ramos 2008 Cancer chemoprevention and chemotherapy: dietary polyphenols and signalling pathways Mol Nutr Food Res 52 507 526 1:CAS:528: DC%2BD1cXms1egt7k%3D 18435439
-
(2008)
Mol Nutr Food Res
, vol.52
, pp. 507-526
-
-
Ramos, S.1
-
46
-
-
0036183074
-
Evidence for consistent patterns between flavonoid structures and cellular activities
-
1:CAS:528:DC%2BD38Xit1WrtLY%3D 12002801
-
F Depeint JM Gee G Williamson IT Johnson 2002 Evidence for consistent patterns between flavonoid structures and cellular activities Proc Nutr Soc 61 97 103 1:CAS:528:DC%2BD38Xit1WrtLY%3D 12002801
-
(2002)
Proc Nutr Soc
, vol.61
, pp. 97-103
-
-
Depeint, F.1
Gee, J.M.2
Williamson, G.3
Johnson, I.T.4
-
47
-
-
46849083081
-
Antioxidant and prooxidant properties of a polyphenol-rich extract from Geranium sanguineum L. in vitro and in vivo
-
18446846
-
M Murzakhmetova S Moldakarimov L Tancheva S Abarova J Serkedjieva 2008 Antioxidant and prooxidant properties of a polyphenol-rich extract from Geranium sanguineum L. in vitro and in vivo Phytother Res 22 746 751 18446846
-
(2008)
Phytother Res
, vol.22
, pp. 746-751
-
-
Murzakhmetova, M.1
Moldakarimov, S.2
Tancheva, L.3
Abarova, S.4
Serkedjieva, J.5
-
48
-
-
70349667448
-
Clarification of the role of quercetin hydroxyl groups in superoxide generation and cell apoptosis by chemical modification
-
1:CAS:528:DC%2BD1MXht1Ghu77O 19734664
-
K Sakao M Fujii DX Hou 2009 Clarification of the role of quercetin hydroxyl groups in superoxide generation and cell apoptosis by chemical modification Biosci Biotechnol Biochem 73 2048 2053 1:CAS:528:DC%2BD1MXht1Ghu77O 19734664
-
(2009)
Biosci Biotechnol Biochem
, vol.73
, pp. 2048-2053
-
-
Sakao, K.1
Fujii, M.2
Hou, D.X.3
-
49
-
-
0034736046
-
Advances in flavonoid research since 1992
-
1:CAS:528:DC%2BD3cXosFent74%3D 11130659
-
JB Harborne CA Williams 2000 Advances in flavonoid research since 1992 Phytochemistry 55 481 504 1:CAS:528:DC%2BD3cXosFent74%3D 11130659
-
(2000)
Phytochemistry
, vol.55
, pp. 481-504
-
-
Harborne, J.B.1
Williams, C.A.2
-
50
-
-
67349235348
-
Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs?
-
1:CAS:528:DC%2BD1MXlt1Kjtrk%3D 19294386
-
S Thomasset N Teller H Cai D Marko DP Berry WP Steward AJ Gescher 2009 Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs? Cancer Chemother Pharmacol 64 201 211 1:CAS:528:DC%2BD1MXlt1Kjtrk%3D 19294386
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 201-211
-
-
Thomasset, S.1
Teller, N.2
Cai, H.3
Marko, D.4
Berry, D.P.5
Steward, W.P.6
Gescher, A.J.7
-
51
-
-
54249083134
-
A dietary anthocyanidin delphinidin induces apoptosis of human prostate cancer PC3 cells in vitro and in vivo: Involvement of nuclear factor-kappaB signaling
-
18922932
-
BB Hafeez IA Siddiqui M Asim A Malik F Afaq VM Adhami M Saleem M Din H Mukhtar 2008 A dietary anthocyanidin delphinidin induces apoptosis of human prostate cancer PC3 cells in vitro and in vivo: involvement of nuclear factor-kappaB signaling Cancer Res 68 8564 8572 18922932
-
(2008)
Cancer Res
, vol.68
, pp. 8564-8572
-
-
Hafeez, B.B.1
Siddiqui, I.A.2
Asim, M.3
Malik, A.4
Afaq, F.5
Adhami, V.M.6
Saleem, M.7
Din, M.8
Mukhtar, H.9
-
52
-
-
33745197329
-
Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity
-
1:CAS:528:DC%2BD28XlvVGkt7k%3D 16618699
-
M Ding R Feng SY Wang L Bowman Y Lu Y Qian V Castranova BH Jiang X Shi 2006 Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity J Biol Chem 281 17359 17368 1:CAS:528:DC%2BD28XlvVGkt7k%3D 16618699
-
(2006)
J Biol Chem
, vol.281
, pp. 17359-17368
-
-
Ding, M.1
Feng, R.2
Wang, S.Y.3
Bowman, L.4
Lu, Y.5
Qian, Y.6
Castranova, V.7
Jiang, B.H.8
Shi, X.9
-
53
-
-
8144229635
-
Induction of apoptosis in human breast adenocarcinoma MCF-7 cells by prodelphinidin B-2 3, 3′-di-O-gallate from Myrica rubra via Fas-mediated pathway
-
1:CAS:528:DC%2BD2cXpvFOltb8%3D 15525446
-
PL Kuo YL Hsu TC Lin LT Lin CC Lin 2004 Induction of apoptosis in human breast adenocarcinoma MCF-7 cells by prodelphinidin B-2 3, 3′-di-O-gallate from Myrica rubra via Fas-mediated pathway J Pharm Pharmacol 56 1399 1406 1:CAS:528:DC%2BD2cXpvFOltb8%3D 15525446
-
(2004)
J Pharm Pharmacol
, vol.56
, pp. 1399-1406
-
-
Kuo, P.L.1
Hsu, Y.L.2
Lin, T.C.3
Lin, L.T.4
Lin, C.C.5
-
54
-
-
32344444354
-
Stability and biotransformation of various dietary anthocyanins in vitro
-
1:CAS:528:DC%2BD28Xis1SgsLo%3D 15834757
-
J Fleschhut F Kratzer G Rechkemmer SE Kulling 2006 Stability and biotransformation of various dietary anthocyanins in vitro Eur J Nutr 45 7 18 1:CAS:528:DC%2BD28Xis1SgsLo%3D 15834757
-
(2006)
Eur J Nutr
, vol.45
, pp. 7-18
-
-
Fleschhut, J.1
Kratzer, F.2
Rechkemmer, G.3
Kulling, S.E.4
-
55
-
-
33646126051
-
A green tea polyphenol, epigalocatechin-3-gallate, induces apoptosis of human hepatocellular carcinoma, possibly through inhibition of Bcl-2 family proteins
-
1:CAS:528:DC%2BD28XksVaisb4%3D 16481065
-
T Nishikawa T Nakajima M Moriguchi M Jo S Sekoguchi M Ishii H Takashima T Katagishi H Kimura M Minami Y Itoh K Kagawa T Okanoue 2006 A green tea polyphenol, epigalocatechin-3-gallate, induces apoptosis of human hepatocellular carcinoma, possibly through inhibition of Bcl-2 family proteins J Hepatol 44 1074 1082 1:CAS:528:DC%2BD28XksVaisb4%3D 16481065
-
(2006)
J Hepatol
, vol.44
, pp. 1074-1082
-
-
Nishikawa, T.1
Nakajima, T.2
Moriguchi, M.3
Jo, M.4
Sekoguchi, S.5
Ishii, M.6
Takashima, H.7
Katagishi, T.8
Kimura, H.9
Minami, M.10
Itoh, Y.11
Kagawa, K.12
Okanoue, T.13
-
56
-
-
55549138348
-
Epigalocatechin-3-gallate (EGCG) downregulates PEA15 and thereby augments TRAIL-mediated apoptosis in malignant glioma
-
1:CAS:528:DC%2BD1cXhtlyiurnE 18948169
-
MD Siegelin A Habel T Gaiser 2008 Epigalocatechin-3-gallate (EGCG) downregulates PEA15 and thereby augments TRAIL-mediated apoptosis in malignant glioma Neurosci Lett 448 161 165 1:CAS:528:DC%2BD1cXhtlyiurnE 18948169
-
(2008)
Neurosci Lett
, vol.448
, pp. 161-165
-
-
Siegelin, M.D.1
Habel, A.2
Gaiser, T.3
-
57
-
-
41149143243
-
Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis
-
1:CAS:528:DC%2BD1cXjslWjtr4%3D 17998943
-
IA Siddiqui A Malik VM Adhami M Asim BB Hafeez S Sarfaraz H Mukhtar 2008 Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis Oncogene 27 2055 2063 1:CAS:528: DC%2BD1cXjslWjtr4%3D 17998943
-
(2008)
Oncogene
, vol.27
, pp. 2055-2063
-
-
Siddiqui, I.A.1
Malik, A.2
Adhami, V.M.3
Asim, M.4
Hafeez, B.B.5
Sarfaraz, S.6
Mukhtar, H.7
-
58
-
-
60749117598
-
Combinatorial effect of epigallocatechin-3-gallate and TRAIL on pancreatic cancer cell death
-
1:CAS:528:DC%2BD1MXht1Cqtrc%3D 19082499
-
A Basu S Haldar 2009 Combinatorial effect of epigallocatechin-3-gallate and TRAIL on pancreatic cancer cell death Int J Oncol 34 281 286 1:CAS:528:DC%2BD1MXht1Cqtrc%3D 19082499
-
(2009)
Int J Oncol
, vol.34
, pp. 281-286
-
-
Basu, A.1
Haldar, S.2
-
60
-
-
55149104161
-
Quercetin: Potentials in the prevention and therapy of disease
-
1:CAS:528:DC%2BD1cXhtFOrtLnJ 18827577
-
SC Bischoff 2008 Quercetin: potentials in the prevention and therapy of disease Curr Opin Clin Nutr Metab Care 11 733 740 1:CAS:528:DC%2BD1cXhtFOrtLnJ 18827577
-
(2008)
Curr Opin Clin Nutr Metab Care
, vol.11
, pp. 733-740
-
-
Bischoff, S.C.1
-
61
-
-
0029999052
-
Phase i clinical trial of the flavonoid quercetin: Pharmacokinetics and evidence for in vivo tyrosine kinase inhibition
-
1:CAS:528:DyaK28Xis1Wltbg%3D 9816216
-
DR Ferry A Smith J Malkhandi DW Fyfe PG deTakats D Anderson J Baker DJ Kerr 1996 Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition Clin Cancer Res 2 659 668 1:CAS:528:DyaK28Xis1Wltbg%3D 9816216
-
(1996)
Clin Cancer Res
, vol.2
, pp. 659-668
-
-
Ferry, D.R.1
Smith, A.2
Malkhandi, J.3
Fyfe, D.W.4
Detakats, P.G.5
Anderson, D.6
Baker, J.7
Kerr, D.J.8
-
62
-
-
33847016908
-
TRAIL apoptosis is enhanced by quercetin through Akt dephosphorylation
-
1:CAS:528:DC%2BD2sXhvFGlsr8%3D 17031854
-
YH Kim YJ Lee 2007 TRAIL apoptosis is enhanced by quercetin through Akt dephosphorylation J Cell Biochem 100 998 1009 1:CAS:528:DC%2BD2sXhvFGlsr8%3D 17031854
-
(2007)
J Cell Biochem
, vol.100
, pp. 998-1009
-
-
Kim, Y.H.1
Lee, Y.J.2
-
63
-
-
42649100263
-
Quercetin augments TRAIL-induced apoptotic death: Involvement of the ERK signal transduction pathway
-
1:CAS:528:DC%2BD1cXlsFOms7o%3D 18377872
-
YH Kim DH Lee JH Jeong ZS Guo YJ Lee 2008 Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway Biochem Pharmacol 75 1946 1958 1:CAS:528:DC%2BD1cXlsFOms7o%3D 18377872
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 1946-1958
-
-
Kim, Y.H.1
Lee, D.H.2
Jeong, J.H.3
Guo, Z.S.4
Lee, Y.J.5
-
64
-
-
34247626395
-
Quercetin enhances CD95- and TRAIL-induced apoptosis in leukemia cell lines
-
1:CAS:528:DC%2BD2sXksFeltL8%3D 17330100
-
M Russo P Nigro R Rosiello R D'Arienzo GL Russo 2007 Quercetin enhances CD95- and TRAIL-induced apoptosis in leukemia cell lines Leukemia 21 1130 1133 1:CAS:528:DC%2BD2sXksFeltL8%3D 17330100
-
(2007)
Leukemia
, vol.21
, pp. 1130-1133
-
-
Russo, M.1
Nigro, P.2
Rosiello, R.3
D'Arienzo, R.4
Russo, G.L.5
-
65
-
-
35148854568
-
Induction of death receptor 5 and suppression of survivin contribute to sensitization of TRAIL-induced cytotoxicity by quercetin in non-small cell lung cancer cells
-
1:CAS:528:DC%2BD2sXhtFeqsL7E 17548900
-
W Chen X Wang J Zhuang L Zhang Y Lin 2007 Induction of death receptor 5 and suppression of survivin contribute to sensitization of TRAIL-induced cytotoxicity by quercetin in non-small cell lung cancer cells Carcinogenesis 28 2114 2121 1:CAS:528:DC%2BD2sXhtFeqsL7E 17548900
-
(2007)
Carcinogenesis
, vol.28
, pp. 2114-2121
-
-
Chen, W.1
Wang, X.2
Zhuang, J.3
Zhang, L.4
Lin, Y.5
-
66
-
-
57349169369
-
Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation
-
1:CAS:528:DC%2BD1cXhsFaks7fK 18980244
-
JY Kim EH Kim SS Park JH Lim TK Kwon KS Choi 2008 Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation J Cell Biochem 105 1386 1398 1:CAS:528:DC%2BD1cXhsFaks7fK 18980244
-
(2008)
J Cell Biochem
, vol.105
, pp. 1386-1398
-
-
Kim, J.Y.1
Kim, E.H.2
Park, S.S.3
Lim, J.H.4
Kwon, T.K.5
Choi, K.S.6
-
67
-
-
34147111354
-
A PKC-Sp1 signaling pathway induces early differentiation of human keratinocytes through upregulation of TSG101
-
1:CAS:528:DC%2BD2sXksV2mtLs%3D 17321722
-
HL You HL Eng SF Hsu CM Chen TC Ye WT Liao MY Huang R Baer JT Cheng 2007 A PKC-Sp1 signaling pathway induces early differentiation of human keratinocytes through upregulation of TSG101 Cell Signal 19 1201 1211 1:CAS:528: DC%2BD2sXksV2mtLs%3D 17321722
-
(2007)
Cell Signal
, vol.19
, pp. 1201-1211
-
-
You, H.L.1
Eng, H.L.2
Hsu, S.F.3
Chen, C.M.4
Ye, T.C.5
Liao, W.T.6
Huang, M.Y.7
Baer, R.8
Cheng, J.T.9
-
68
-
-
34748906001
-
Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts
-
1:CAS:528:DC%2BD2sXhtVCgur%2FL 17876056
-
FH Psahoulia KG Drosopoulos L Doubravska L Andera A Pintzas 2007 Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts Mol Cancer Ther 6 2591 2599 1:CAS:528:DC%2BD2sXhtVCgur%2FL 17876056
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2591-2599
-
-
Psahoulia, F.H.1
Drosopoulos, K.G.2
Doubravska, L.3
Andera, L.4
Pintzas, A.5
-
69
-
-
65949095390
-
Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells
-
1:CAS:528:DC%2BD1MXkvFentro%3D 18971417
-
MD Siegelin DE Reuss A Habel A Rami A von Deimling 2009 Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells Neuro Oncol 11 122 131 1:CAS:528:DC%2BD1MXkvFentro%3D 18971417
-
(2009)
Neuro Oncol
, vol.11
, pp. 122-131
-
-
Siegelin, M.D.1
Reuss, D.E.2
Habel, A.3
Rami, A.4
Von Deimling, A.5
-
70
-
-
30444457090
-
Dihydroflavonol BB-1, an extract of natural plant Blumea balsamifera, abrogates TRAIL resistance in leukemia cells
-
1:CAS:528:DC%2BD28Xms1ersA%3D%3D 16195335
-
H Hasegawa Y Yamada K Komiyama M Hayashi M Ishibashi T Yoshida T Sakai T Koyano TS Kam K Murata K Sugahara K Tsuruda N Akamatsu K Tsukasaki M Masuda N Takasu S Kamihira 2006 Dihydroflavonol BB-1, an extract of natural plant Blumea balsamifera, abrogates TRAIL resistance in leukemia cells Blood 107 679 688 1:CAS:528:DC%2BD28Xms1ersA%3D%3D 16195335
-
(2006)
Blood
, vol.107
, pp. 679-688
-
-
Hasegawa, H.1
Yamada, Y.2
Komiyama, K.3
Hayashi, M.4
Ishibashi, M.5
Yoshida, T.6
Sakai, T.7
Koyano, T.8
Kam, T.S.9
Murata, K.10
Sugahara, K.11
Tsuruda, K.12
Akamatsu, N.13
Tsukasaki, K.14
Masuda, M.15
Takasu, N.16
Kamihira, S.17
-
71
-
-
50149121804
-
Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis
-
1:CAS:528:DC%2BD1cXhtVOit7zJ 18680719
-
T Yoshida M Konishi M Horinaka T Yasuda AE Goda H Taniguchi K Yano M Wakada T Sakai 2008 Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis Biochem Biophys Res Commun 375 129 133 1:CAS:528:DC%2BD1cXhtVOit7zJ 18680719
-
(2008)
Biochem Biophys Res Commun
, vol.375
, pp. 129-133
-
-
Yoshida, T.1
Konishi, M.2
Horinaka, M.3
Yasuda, T.4
Goda, A.E.5
Taniguchi, H.6
Yano, K.7
Wakada, M.8
Sakai, T.9
-
72
-
-
3142583640
-
Effect of dietary flavonols on oestrogen receptor transactivation and cell death induction
-
1:CAS:528:DC%2BD2cXltlGmu7o%3D 15182386
-
LK Leung LS Po TY Lau YM Yuen 2004 Effect of dietary flavonols on oestrogen receptor transactivation and cell death induction Br J Nutr 91 831 839 1:CAS:528:DC%2BD2cXltlGmu7o%3D 15182386
-
(2004)
Br J Nutr
, vol.91
, pp. 831-839
-
-
Leung, L.K.1
Po, L.S.2
Lau, T.Y.3
Yuen, Y.M.4
-
73
-
-
56249131797
-
The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin
-
1:CAS:528:DC%2BD1cXhtlGgs77P 19001439
-
MD Siegelin DE Reuss A Habel C Herold-Mende A von Deimling 2008 The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin Mol Cancer Ther 7 3566 3574 1:CAS:528:DC%2BD1cXhtlGgs77P 19001439
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3566-3574
-
-
Siegelin, M.D.1
Reuss, D.E.2
Habel, A.3
Herold-Mende, C.4
Von Deimling, A.5
-
74
-
-
69849092498
-
Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2
-
1:CAS:528:DC%2BD1MXptlanu78%3D 19398149
-
MD Siegelin T Gaiser A Habel Y Siegelin 2009 Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2 Cancer Lett 283 230 238 1:CAS:528: DC%2BD1MXptlanu78%3D 19398149
-
(2009)
Cancer Lett
, vol.283
, pp. 230-238
-
-
Siegelin, M.D.1
Gaiser, T.2
Habel, A.3
Siegelin, Y.4
-
75
-
-
0036682276
-
Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II
-
1:CAS:528:DC%2BD38XlvFelt7k%3D 12154014
-
R Ravi A Bedi 2002 Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II Cancer Res 62 4180 4185 1:CAS:528:DC%2BD38XlvFelt7k%3D 12154014
-
(2002)
Cancer Res
, vol.62
, pp. 4180-4185
-
-
Ravi, R.1
Bedi, A.2
-
76
-
-
33646574281
-
The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand
-
1:CAS:528:DC%2BD28XjvFCktrc%3D 16648565
-
M Horinaka T Yoshida T Shiraishi S Nakata M Wakada T Sakai 2006 The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand Mol Cancer Ther 5 945 951 1:CAS:528:DC%2BD28XjvFCktrc%3D 16648565
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 945-951
-
-
Horinaka, M.1
Yoshida, T.2
Shiraishi, T.3
Nakata, S.4
Wakada, M.5
Sakai, T.6
-
77
-
-
20744456317
-
The combination of TRAIL and luteolin enhances apoptosis in human cervical cancer HeLa cells
-
1:CAS:528:DC%2BD2MXlvVent7g%3D 15963948
-
M Horinaka T Yoshida T Shiraishi S Nakata M Wakada R Nakanishi H Nishino T Sakai 2005 The combination of TRAIL and luteolin enhances apoptosis in human cervical cancer HeLa cells Biochem Biophys Res Commun 333 833 838 1:CAS:528:DC%2BD2MXlvVent7g%3D 15963948
-
(2005)
Biochem Biophys Res Commun
, vol.333
, pp. 833-838
-
-
Horinaka, M.1
Yoshida, T.2
Shiraishi, T.3
Nakata, S.4
Wakada, M.5
Nakanishi, R.6
Nishino, H.7
Sakai, T.8
-
78
-
-
24744449776
-
Protein kinase C inhibition and x-linked inhibitor of apoptosis protein degradation contribute to the sensitization effect of luteolin on tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cancer cells
-
1:CAS:528:DC%2BD2MXpslaiu70%3D 16140950
-
RX Shi CN Ong HM Shen 2005 Protein kinase C inhibition and x-linked inhibitor of apoptosis protein degradation contribute to the sensitization effect of luteolin on tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cancer cells Cancer Res 65 7815 7823 1:CAS:528:DC%2BD2MXpslaiu70%3D 16140950
-
(2005)
Cancer Res
, vol.65
, pp. 7815-7823
-
-
Shi, R.X.1
Ong, C.N.2
Shen, H.M.3
-
79
-
-
33845258748
-
Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis
-
1:CAS:528:DC%2BD28Xht1Kgs7%2FP 16931628
-
SC Fas S Baumann JY Zhu M Giaisi MK Treiber U Mahlknecht PH Krammer M Li-Weber 2006 Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis Blood 108 3700 3706 1:CAS:528:DC%2BD28Xht1Kgs7%2FP 16931628
-
(2006)
Blood
, vol.108
, pp. 3700-3706
-
-
Fas, S.C.1
Baumann, S.2
Zhu, J.Y.3
Giaisi, M.4
Treiber, M.K.5
Mahlknecht, U.6
Krammer, P.H.7
Li-Weber, M.8
-
80
-
-
70350346849
-
Reactive oxygen species up-regulate p53 and Puma; A possible mechanism for apoptosis during combined treatment with TRAIL and wogonin
-
1:CAS:528:DC%2BD1MXhtVelt7bN 19438509
-
DH Lee JG Rhee YJ Lee 2009 Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin Br J Pharmacol 157 1189 1202 1:CAS:528:DC%2BD1MXhtVelt7bN 19438509
-
(2009)
Br J Pharmacol
, vol.157
, pp. 1189-1202
-
-
Lee, D.H.1
Rhee, J.G.2
Lee, Y.J.3
-
81
-
-
70350336226
-
Molecular crosstalk between TRAIL and natural antioxidants in the treatment of cancer
-
1:CAS:528:DC%2BD1MXhtVelt7bM 19664138
-
SA Rushworth O Micheau 2009 Molecular crosstalk between TRAIL and natural antioxidants in the treatment of cancer Br J Pharmacol 157 1186 1188 1:CAS:528:DC%2BD1MXhtVelt7bM 19664138
-
(2009)
Br J Pharmacol
, vol.157
, pp. 1186-1188
-
-
Rushworth, S.A.1
Micheau, O.2
-
82
-
-
67649637824
-
Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling
-
1:CAS:528:DC%2BD1MXovFSktb0%3D 18829980
-
G Kallifatidis V Rausch B Baumann A Apel BM Beckermann A Groth J Mattern Z Li A Kolb G Moldenhauer P Altevogt T Wirth J Werner P Schemmer MW Buchler AV Salnikov I Herr 2009 Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling Gut 58 949 963 1:CAS:528: DC%2BD1MXovFSktb0%3D 18829980
-
(2009)
Gut
, vol.58
, pp. 949-963
-
-
Kallifatidis, G.1
Rausch, V.2
Baumann, B.3
Apel, A.4
Beckermann, B.M.5
Groth, A.6
Mattern, J.7
Li, Z.8
Kolb, A.9
Moldenhauer, G.10
Altevogt, P.11
Wirth, T.12
Werner, J.13
Schemmer, P.14
Buchler, M.W.15
Salnikov, A.V.16
Herr, I.17
-
83
-
-
67449135860
-
Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs
-
1:CAS:528:DC%2BD1MXnvVWktr4%3D 19397969
-
J Peng Q Qi Q You R Hu W Liu F Feng G Wang Q Guo 2009 Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs J Ethnopharmacol 124 257 262 1:CAS:528:DC%2BD1MXnvVWktr4%3D 19397969
-
(2009)
J Ethnopharmacol
, vol.124
, pp. 257-262
-
-
Peng, J.1
Qi, Q.2
You, Q.3
Hu, R.4
Liu, W.5
Feng, F.6
Wang, G.7
Guo, Q.8
-
84
-
-
55349089182
-
Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells
-
1:CAS:528:DC%2BD1cXhtlSkur%2FF 18974136
-
H Taniguchi T Yoshida M Horinaka T Yasuda AE Goda M Konishi M Wakada K Kataoka T Yoshikawa T Sakai 2008 Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells Cancer Res 68 8918 8927 1:CAS:528:DC%2BD1cXhtlSkur%2FF 18974136
-
(2008)
Cancer Res
, vol.68
, pp. 8918-8927
-
-
Taniguchi, H.1
Yoshida, T.2
Horinaka, M.3
Yasuda, T.4
Goda, A.E.5
Konishi, M.6
Wakada, M.7
Kataoka, K.8
Yoshikawa, T.9
Sakai, T.10
-
85
-
-
46749111467
-
Soy isoflavones, estrogen therapy, and breast cancer risk: Analysis and commentary
-
18522734
-
MJ Messina CE Wood 2008 Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentary Nutr J 7 17 18522734
-
(2008)
Nutr J
, vol.7
, pp. 17
-
-
Messina, M.J.1
Wood, C.E.2
-
86
-
-
0036064773
-
Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGF-R inhibitor-enhanced TRAIL-induced apoptosis
-
1:CAS:528:DC%2BD38XltFertLg%3D 12150980
-
SY Park DW Seol 2002 Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGF-R inhibitor-enhanced TRAIL-induced apoptosis Biochem Biophys Res Commun 295 515 518 1:CAS:528:DC%2BD38XltFertLg%3D 12150980
-
(2002)
Biochem Biophys Res Commun
, vol.295
, pp. 515-518
-
-
Park, S.Y.1
Seol, D.W.2
-
87
-
-
3042732298
-
The combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) and Genistein is effective in inhibiting pancreatic cancer growth
-
1:CAS:528:DC%2BD2cXmtVSitLY%3D 15211111
-
F Nozawa A Itami M Saruc M Kim J Standop KS Picha KH Cowan PM Pour 2004 The combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) and Genistein is effective in inhibiting pancreatic cancer growth Pancreas 29 45 52 1:CAS:528:DC%2BD2cXmtVSitLY%3D 15211111
-
(2004)
Pancreas
, vol.29
, pp. 45-52
-
-
Nozawa, F.1
Itami, A.2
Saruc, M.3
Kim, M.4
Standop, J.5
Picha, K.S.6
Cowan, K.H.7
Pour, P.M.8
-
88
-
-
33344476441
-
The activation of ERK1/2 via a tyrosine kinase pathway attenuates trail-induced apoptosis in HeLa cells
-
1:CAS:528:DC%2BD2MXht1eltLvN
-
MW Lee JH Bach HJ Lee DY Lee WS Joo YS Kim SC Park KY Kim WB Lee SS Kim 2005 The activation of ERK1/2 via a tyrosine kinase pathway attenuates trail-induced apoptosis in HeLa cells Cancer Investig 23 586 592 1:CAS:528:DC%2BD2MXht1eltLvN
-
(2005)
Cancer Investig
, vol.23
, pp. 586-592
-
-
Lee, M.W.1
Bach, J.H.2
Lee, H.J.3
Lee, D.Y.4
Joo, W.S.5
Kim, Y.S.6
Park, S.C.7
Kim, K.Y.8
Lee, W.B.9
Kim, S.S.10
-
89
-
-
67349246450
-
Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells
-
1:CAS:528:DC%2BD1MXmvF2itb0%3D 19497411
-
CY Jin C Park GY Kim SJ Lee WJ Kim YH Choi 2009 Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells Chem Biol Interact 180 143 150 1:CAS:528:DC%2BD1MXmvF2itb0%3D 19497411
-
(2009)
Chem Biol Interact
, vol.180
, pp. 143-150
-
-
Jin, C.Y.1
Park, C.2
Kim, G.Y.3
Lee, S.J.4
Kim, W.J.5
Choi, Y.H.6
-
90
-
-
70349332934
-
Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage
-
1:CAS:528:DC%2BD1MXovVOhtr0%3D 19617819
-
CY Jin C Park SK Moon GY Kim TK Kwon SJ Lee WJ Kim YH Choi 2009 Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage Anticancer Drugs 20 713 722 1:CAS:528: DC%2BD1MXovVOhtr0%3D 19617819
-
(2009)
Anticancer Drugs
, vol.20
, pp. 713-722
-
-
Jin, C.Y.1
Park, C.2
Moon, S.K.3
Kim, G.Y.4
Kwon, T.K.5
Lee, S.J.6
Kim, W.J.7
Choi, Y.H.8
-
91
-
-
34648825655
-
Genistein sensitizes TRAIL-resistant human gastric adenocarcinoma AGS cells through activation of caspase-3
-
1:CAS:528:DC%2BD2sXhtFSnt7vK 17689858
-
CY Jin C Park J Cheong BT Choi TH Lee JD Lee WH Lee GY Kim CH Ryu YH Choi 2007 Genistein sensitizes TRAIL-resistant human gastric adenocarcinoma AGS cells through activation of caspase-3 Cancer Lett 257 56 64 1:CAS:528: DC%2BD2sXhtFSnt7vK 17689858
-
(2007)
Cancer Lett
, vol.257
, pp. 56-64
-
-
Jin, C.Y.1
Park, C.2
Cheong, J.3
Choi, B.T.4
Lee, T.H.5
Lee, J.D.6
Lee, W.H.7
Kim, G.Y.8
Ryu, C.H.9
Choi, Y.H.10
-
92
-
-
61449099307
-
Genistein enhances proteasomal degradation of the short isoform of FLIP in malignant glioma cells and thereby augments TRAIL-mediated apoptosis
-
1:CAS:528:DC%2BD1MXivVelu7k%3D 19356600
-
MD Siegelin Y Siegelin A Habel T Gaiser 2009 Genistein enhances proteasomal degradation of the short isoform of FLIP in malignant glioma cells and thereby augments TRAIL-mediated apoptosis Neurosci Lett 453 92 97 1:CAS:528:DC%2BD1MXivVelu7k%3D 19356600
-
(2009)
Neurosci Lett
, vol.453
, pp. 92-97
-
-
Siegelin, M.D.1
Siegelin, Y.2
Habel, A.3
Gaiser, T.4
-
93
-
-
63249129117
-
Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, Bcl-2
-
1:CAS:528:DC%2BD1MXktFalt7o%3D 19429088
-
MD Siegelin T Gaiser A Habel Y Siegelin 2009 Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, Bcl-2 Neurosci Lett 454 223 228 1:CAS:528:DC%2BD1MXktFalt7o%3D 19429088
-
(2009)
Neurosci Lett
, vol.454
, pp. 223-228
-
-
Siegelin, M.D.1
Gaiser, T.2
Habel, A.3
Siegelin, Y.4
-
94
-
-
52649126205
-
Butein sensitizes human leukemia cells to apoptosis induced by tumor necrosis factor-related apoptosis inducing ligand (TRAIL)
-
1:CAS:528:DC%2BD1cXhtFegtbfJ 18806962
-
N Kim 2008 Butein sensitizes human leukemia cells to apoptosis induced by tumor necrosis factor-related apoptosis inducing ligand (TRAIL) Arch Pharm Res 31 1179 1186 1:CAS:528:DC%2BD1cXhtFegtbfJ 18806962
-
(2008)
Arch Pharm Res
, vol.31
, pp. 1179-1186
-
-
Kim, N.1
-
95
-
-
67349188370
-
Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells
-
1:CAS:528:DC%2BD1cXht1yntr3F 19568915
-
T Yoshida M Horinaka M Takara M Tsuchihashi N Mukai M Wakada T Sakai 2008 Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells Environ Health Prev Med 13 281 287 1:CAS:528:DC%2BD1cXht1yntr3F 19568915
-
(2008)
Environ Health Prev Med
, vol.13
, pp. 281-287
-
-
Yoshida, T.1
Horinaka, M.2
Takara, M.3
Tsuchihashi, M.4
Mukai, N.5
Wakada, M.6
Sakai, T.7
-
96
-
-
0042710263
-
Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells
-
1:CAS:528:DC%2BD3sXhtlOit7s%3D 12533677
-
D Deeb YX Xu H Jiang X Gao N Janakiraman RA Chapman SC Gautam 2003 Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells Mol Cancer Ther 2 95 103 1:CAS:528:DC%2BD3sXhtlOit7s%3D 12533677
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 95-103
-
-
Deeb, D.1
Xu, Y.X.2
Jiang, H.3
Gao, X.4
Janakiraman, N.5
Chapman, R.A.6
Gautam, S.C.7
-
97
-
-
1642576201
-
Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol
-
1:CAS:528:DC%2BD2cXkslyrsA%3D%3D 14729643
-
S Fulda KM Debatin 2004 Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol Cancer Res 64 337 346 1:CAS:528:DC%2BD2cXkslyrsA%3D%3D 14729643
-
(2004)
Cancer Res
, vol.64
, pp. 337-346
-
-
Fulda, S.1
Debatin, K.M.2
-
98
-
-
14844312113
-
Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling
-
1:CAS:528:DC%2BD2MXitF2isbw%3D 15763656
-
S Fulda KM Debatin 2005 Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling Eur J Cancer 41 786 798 1:CAS:528:DC%2BD2MXitF2isbw%3D 15763656
-
(2005)
Eur J Cancer
, vol.41
, pp. 786-798
-
-
Fulda, S.1
Debatin, K.M.2
-
99
-
-
10644246821
-
Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells
-
1:CAS:528:DC%2BD2cXhtVWgtb%2FK 15480430
-
D Delmas C Rebe O Micheau A Athias P Gambert S Grazide G Laurent N Latruffe E Solary 2004 Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells Oncogene 23 8979 8986 1:CAS:528:DC%2BD2cXhtVWgtb%2FK 15480430
-
(2004)
Oncogene
, vol.23
, pp. 8979-8986
-
-
Delmas, D.1
Rebe, C.2
Micheau, O.3
Athias, A.4
Gambert, P.5
Grazide, S.6
Laurent, G.7
Latruffe, N.8
Solary, E.9
-
100
-
-
36448992018
-
Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4′, 5 tri-hydroxystilbene): Molecular mechanisms and therapeutic potential
-
17718901
-
S Shankar Q Chen I Siddiqui K Sarva RK Srivastava 2007 Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4′, 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potential J Mol Signal 2 7 17718901
-
(2007)
J Mol Signal
, vol.2
, pp. 7
-
-
Shankar, S.1
Chen, Q.2
Siddiqui, I.3
Sarva, K.4
Srivastava, R.K.5
-
101
-
-
34648813877
-
Molecular mechanisms of resveratrol (3, 4, 5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells
-
1:CAS:528:DC%2BD2sXhtVKrtrbN 17636462
-
S Shankar I Siddiqui RK Srivastava 2007 Molecular mechanisms of resveratrol (3, 4, 5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells Mol Cell Biochem 304 273 285 1:CAS:528:DC%2BD2sXhtVKrtrbN 17636462
-
(2007)
Mol Cell Biochem
, vol.304
, pp. 273-285
-
-
Shankar, S.1
Siddiqui, I.2
Srivastava, R.K.3
-
102
-
-
35648975568
-
Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms
-
1:CAS:528:DC%2BD2sXhtlyrtL7L 17823925
-
C Gill SE Walsh C Morrissey JM Fitzpatrick RW Watson 2007 Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms Prostate 67 1641 1653 1:CAS:528:DC%2BD2sXhtlyrtL7L 17823925
-
(2007)
Prostate
, vol.67
, pp. 1641-1653
-
-
Gill, C.1
Walsh, S.E.2
Morrissey, C.3
Fitzpatrick, J.M.4
Watson, R.W.5
-
104
-
-
39549088497
-
Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression
-
1:CAS:528:DC%2BD1cXisVWjtbg%3D 18222423
-
VN Ivanov MA Partridge GE Johnson SX Huang H Zhou TK Hei 2008 Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression Exp Cell Res 314 1163 1176 1:CAS:528:DC%2BD1cXisVWjtbg%3D 18222423
-
(2008)
Exp Cell Res
, vol.314
, pp. 1163-1176
-
-
Ivanov, V.N.1
Partridge, M.A.2
Johnson, G.E.3
Huang, S.X.4
Zhou, H.5
Hei, T.K.6
-
105
-
-
34547786651
-
Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis
-
1:CAS:528:DC%2BD2sXhtVaksrvO 17645780
-
T Yoshida T Shiraishi M Horinaka S Nakata T Yasuda AE Goda M Wakada Y Mizutani T Miki A Nishikawa T Sakai 2007 Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis Cancer Sci 98 1417 1423 1:CAS:528:DC%2BD2sXhtVaksrvO 17645780
-
(2007)
Cancer Sci
, vol.98
, pp. 1417-1423
-
-
Yoshida, T.1
Shiraishi, T.2
Horinaka, M.3
Nakata, S.4
Yasuda, T.5
Goda, A.E.6
Wakada, M.7
Mizutani, Y.8
Miki, T.9
Nishikawa, A.10
Sakai, T.11
-
106
-
-
51049115354
-
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis
-
1:CAS:528:DC%2BD1cXoslCnsrk%3D 18645030
-
SM Raja S Chen P Yue TM Acker B Lefkove JL Arbiser FR Khuri SY Sun 2008 The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis Mol Cancer Ther 7 2212 2223 1:CAS:528:DC%2BD1cXoslCnsrk%3D 18645030
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2212-2223
-
-
Raja, S.M.1
Chen, S.2
Yue, P.3
Acker, T.M.4
Lefkove, B.5
Arbiser, J.L.6
Khuri, F.R.7
Sun, S.Y.8
-
107
-
-
34548590339
-
Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin
-
1:CAS:528:DC%2BD2sXpvFKju74%3D 17804742
-
YG Son EH Kim JY Kim SU Kim TK Kwon AR Yoon CO Yun KS Choi 2007 Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin Cancer Res 67 8274 8284 1:CAS:528:DC%2BD2sXpvFKju74%3D 17804742
-
(2007)
Cancer Res
, vol.67
, pp. 8274-8284
-
-
Son, Y.G.1
Kim, E.H.2
Kim, J.Y.3
Kim, S.U.4
Kwon, T.K.5
Yoon, A.R.6
Yun, C.O.7
Choi, K.S.8
-
108
-
-
55949095821
-
Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells
-
1:CAS:528:DC%2BD1cXhtl2qtLbM 18755156
-
S Reuter S Eifes M Dicato BB Aggarwal M Diederich 2008 Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells Biochem Pharmacol 76 1340 1351 1:CAS:528: DC%2BD1cXhtl2qtLbM 18755156
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 1340-1351
-
-
Reuter, S.1
Eifes, S.2
Dicato, M.3
Aggarwal, B.B.4
Diederich, M.5
-
109
-
-
38349011007
-
Curcumin: Preventive and therapeutic properties in laboratory studies and clinical trials
-
1:CAS:528:DC%2BD1cXmt1yksQ%3D%3D 18370854
-
AS Strimpakos RA Sharma 2008 Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials Antioxid Redox Signal 10 511 545 1:CAS:528:DC%2BD1cXmt1yksQ%3D%3D 18370854
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 511-545
-
-
Strimpakos, A.S.1
Sharma, R.A.2
-
110
-
-
28444464762
-
Chemosensitization of hormone-refractory prostate cancer cells by curcumin to TRAIL-induced apoptosis
-
1:CAS:528:DC%2BD2MXhtlWntr%2FE 16471035
-
DD Deeb H Jiang X Gao G Divine SA Dulchavsky SC Gautam 2005 Chemosensitization of hormone-refractory prostate cancer cells by curcumin to TRAIL-induced apoptosis J Exp Ther Oncol 5 81 91 1:CAS:528:DC%2BD2MXhtlWntr%2FE 16471035
-
(2005)
J Exp Ther Oncol
, vol.5
, pp. 81-91
-
-
Deeb, D.D.1
Jiang, H.2
Gao, X.3
Divine, G.4
Dulchavsky, S.A.5
Gautam, S.C.6
-
111
-
-
4444294803
-
Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation
-
1:CAS:528:DC%2BD2cXls1amsr8%3D 15252141
-
D Deeb H Jiang X Gao MS Hafner H Wong G Divine RA Chapman SA Dulchavsky SC Gautam 2004 Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation Mol Cancer Ther 3 803 812 1:CAS:528:DC%2BD2cXls1amsr8%3D 15252141
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 803-812
-
-
Deeb, D.1
Jiang, H.2
Gao, X.3
Hafner, M.S.4
Wong, H.5
Divine, G.6
Chapman, R.A.7
Dulchavsky, S.A.8
Gautam, S.C.9
-
112
-
-
34247229225
-
Curcumin [1, 7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3, 5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway
-
1:CAS:528:DC%2BD2sXltFehur4%3D 17289836
-
D Deeb H Jiang X Gao S Al-Holou AL Danyluk SA Dulchavsky SC Gautam 2007 Curcumin [1, 7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3, 5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway J Pharmacol Exp Ther 321 616 625 1:CAS:528:DC%2BD2sXltFehur4%3D 17289836
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 616-625
-
-
Deeb, D.1
Jiang, H.2
Gao, X.3
Al-Holou, S.4
Danyluk, A.L.5
Dulchavsky, S.A.6
Gautam, S.C.7
-
113
-
-
61449198651
-
Therapeutic efficacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer
-
1:CAS:528:DC%2BD1MXnslWhu74%3D 19192720
-
T Andrzejewski D Deeb X Gao A Danyluk AS Arbab SA Dulchavsky SC Gautam 2008 Therapeutic efficacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer Oncol Res 17 257 267 1:CAS:528: DC%2BD1MXnslWhu74%3D 19192720
-
(2008)
Oncol Res
, vol.17
, pp. 257-267
-
-
Andrzejewski, T.1
Deeb, D.2
Gao, X.3
Danyluk, A.4
Arbab, A.S.5
Dulchavsky, S.A.6
Gautam, S.C.7
-
114
-
-
36448981749
-
Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: Molecular mechanisms of apoptosis, migration and angiogenesis
-
17916240
-
S Shankar Q Chen K Sarva I Siddiqui RK Srivastava 2007 Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: molecular mechanisms of apoptosis, migration and angiogenesis J Mol Signal 2 10 17916240
-
(2007)
J Mol Signal
, vol.2
, pp. 10
-
-
Shankar, S.1
Chen, Q.2
Sarva, K.3
Siddiqui, I.4
Srivastava, R.K.5
-
115
-
-
39749093675
-
Curcumin sensitizes TRAIL-resistant xenografts: Molecular mechanisms of apoptosis, metastasis and angiogenesis
-
18226269
-
S Shankar S Ganapathy Q Chen RK Srivastava 2008 Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis Mol Cancer 7 16 18226269
-
(2008)
Mol Cancer
, vol.7
, pp. 16
-
-
Shankar, S.1
Ganapathy, S.2
Chen, Q.3
Srivastava, R.K.4
-
116
-
-
33749568038
-
Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation
-
1:CAS:528:DC%2BD28XhtVOmu77J 16613838
-
EM Jung JW Park KS Choi HI Lee KS Lee TK Kwon 2006 Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation Carcinogenesis 27 2008 2017 1:CAS:528:DC%2BD28XhtVOmu77J 16613838
-
(2006)
Carcinogenesis
, vol.27
, pp. 2008-2017
-
-
Jung, E.M.1
Park, J.W.2
Choi, K.S.3
Lee, H.I.4
Lee, K.S.5
Kwon, T.K.6
-
117
-
-
27744609173
-
Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)
-
1:CAS:528:DC%2BD2MXhtFCjt7vN 15987718
-
EM Jung JH Lim TJ Lee JW Park KS Choi TK Kwon 2005 Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5) Carcinogenesis 26 1905 1913 1:CAS:528:DC%2BD2MXhtFCjt7vN 15987718
-
(2005)
Carcinogenesis
, vol.26
, pp. 1905-1913
-
-
Jung, E.M.1
Lim, J.H.2
Lee, T.J.3
Park, J.W.4
Choi, K.S.5
Kwon, T.K.6
-
118
-
-
55749098119
-
Curcumin suppresses constitutive activation of nuclear factor-kappa B and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines
-
1:CAS:528:DC%2BD1cXht1ensb%2FL 18852135
-
AR Hussain M Ahmed NA Al-Jomah AS Khan P Manogaran M Sultana J Abubaker LC Platanias KS Al-Kuraya S Uddin 2008 Curcumin suppresses constitutive activation of nuclear factor-kappa B and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines Mol Cancer Ther 7 3318 3329 1:CAS:528:DC%2BD1cXht1ensb%2FL 18852135
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3318-3329
-
-
Hussain, A.R.1
Ahmed, M.2
Al-Jomah, N.A.3
Khan, A.S.4
Manogaran, P.5
Sultana, M.6
Abubaker, J.7
Platanias, L.C.8
Al-Kuraya, K.S.9
Uddin, S.10
-
119
-
-
23044494635
-
Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria
-
16416600
-
X Gao D Deeb H Jiang YB Liu SA Dulchavsky SC Gautam 2005 Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria J Exp Ther Oncol 5 39 48 16416600
-
(2005)
J Exp Ther Oncol
, vol.5
, pp. 39-48
-
-
Gao, X.1
Deeb, D.2
Jiang, H.3
Liu, Y.B.4
Dulchavsky, S.A.5
Gautam, S.C.6
-
120
-
-
34147138418
-
Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cancer cells
-
1:CAS:528:DC%2BD2sXivV2nt78%3D 17363495
-
AM Kamat G Sethi BB Aggarwal 2007 Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cancer cells Mol Cancer Ther 6 1022 1030 1:CAS:528:DC%2BD2sXivV2nt78%3D 17363495
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1022-1030
-
-
Kamat, A.M.1
Sethi, G.2
Aggarwal, B.B.3
-
121
-
-
33947427176
-
Curcumin enhances Apo2L/TRAIL-induced apoptosis in chemoresistant ovarian cancer cells
-
DOI 10.1016/j.ygyno.2006.10.050, PII S0090825806008936
-
H Wahl L Tan K Griffith M Choi JR Liu 2007 Curcumin enhances Apo2L/TRAIL-induced apoptosis in chemoresistant ovarian cancer cells Gynecol Oncol 105 104 112 1:CAS:528:DC%2BD2sXjsVems7g%3D 17174384 (Pubitemid 46442871)
-
(2007)
Gynecologic Oncology
, vol.105
, Issue.1
, pp. 104-112
-
-
Wahl, H.1
Tan, L.2
Griffith, K.3
Choi, M.4
Liu, J.R.5
-
122
-
-
63149175753
-
A rice bran polyphenol, cycloartenyl ferulate, elicits apoptosis in human colorectal adenocarcinoma SW480 and sensitizes metastatic SW620 cells to TRAIL-induced apoptosis
-
1:CAS:528:DC%2BD1MXktF2rsr8%3D 19426686
-
CK Kong WS Lam LC Chiu VE Ooi SS Sun YS Wong 2009 A rice bran polyphenol, cycloartenyl ferulate, elicits apoptosis in human colorectal adenocarcinoma SW480 and sensitizes metastatic SW620 cells to TRAIL-induced apoptosis Biochem Pharmacol 77 1487 1496 1:CAS:528:DC%2BD1MXktF2rsr8%3D 19426686
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 1487-1496
-
-
Kong, C.K.1
Lam, W.S.2
Chiu, L.C.3
Ooi, V.E.4
Sun, S.S.5
Wong, Y.S.6
-
123
-
-
0031019034
-
Flavopiridol (L86-8275): Selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells
-
1:CAS:528:DyaK2sXhsVOmtro%3D 9815683
-
M Drees WA Dengler T Roth H Labonte J Mayo L Malspeis M Grever EA Sausville HH Fiebig 1997 Flavopiridol (L86-8275): selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells Clin Cancer Res 3 273 279 1:CAS:528:DyaK2sXhsVOmtro%3D 9815683
-
(1997)
Clin Cancer Res
, vol.3
, pp. 273-279
-
-
Drees, M.1
Dengler, W.A.2
Roth, T.3
Labonte, H.4
Mayo, J.5
Malspeis, L.6
Grever, M.7
Sausville, E.A.8
Fiebig, H.H.9
-
124
-
-
3042536038
-
Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol
-
1:CAS:528:DC%2BD2cXltFWls7o%3D 15217973
-
GI Shapiro 2004 Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol Clin Cancer Res 10 4270s 4275s 1:CAS:528:DC%2BD2cXltFWls7o%3D 15217973
-
(2004)
Clin Cancer Res
, vol.10
-
-
Shapiro, G.I.1
-
125
-
-
2442663096
-
Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells
-
1:CAS:528:DC%2BD2cXktVWhsb4%3D 15150106
-
M Taniai A Grambihler H Higuchi N Werneburg SF Bronk DJ Farrugia SH Kaufmann GJ Gores 2004 Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells Cancer Res 64 3517 3524 1:CAS:528:DC%2BD2cXktVWhsb4%3D 15150106
-
(2004)
Cancer Res
, vol.64
, pp. 3517-3524
-
-
Taniai, M.1
Grambihler, A.2
Higuchi, H.3
Werneburg, N.4
Bronk, S.F.5
Farrugia, D.J.6
Kaufmann, S.H.7
Gores, G.J.8
-
126
-
-
8844228917
-
Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation
-
1:CAS:528:DC%2BD2cXovVGitb8%3D 15385934
-
RR Rosato Y Dai JA Almenara SC Maggio S Grant 2004 Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation Leukemia 18 1780 1788 1:CAS:528:DC%2BD2cXovVGitb8%3D 15385934
-
(2004)
Leukemia
, vol.18
, pp. 1780-1788
-
-
Rosato, R.R.1
Dai, Y.2
Almenara, J.A.3
Maggio, S.C.4
Grant, S.5
-
127
-
-
34447509844
-
The cyclin-dependent kinase inhibitor flavopiridol sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis
-
1:CAS:528:DC%2BD28XotFKhtb4%3D 16820931
-
K Miyashita K Shiraki H Fuke T Inoue Y Yamanaka Y Yamaguchi N Yamamoto K Ito K Sugimoto T Nakano 2006 The cyclin-dependent kinase inhibitor flavopiridol sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis Int J Mol Med 18 249 256 1:CAS:528:DC%2BD28XotFKhtb4%3D 16820931
-
(2006)
Int J Mol Med
, vol.18
, pp. 249-256
-
-
Miyashita, K.1
Shiraki, K.2
Fuke, H.3
Inoue, T.4
Yamanaka, Y.5
Yamaguchi, Y.6
Yamamoto, N.7
Ito, K.8
Sugimoto, K.9
Nakano, T.10
-
128
-
-
33749004024
-
Flavopiridol induces cellular FLICE-inhibitory protein degradation by the proteasome and promotes TRAIL-induced early signaling and apoptosis in breast tumor cells
-
1:CAS:528:DC%2BD28XovF2ht7s%3D 16951203
-
C Palacios R Yerbes A Lopez-Rivas 2006 Flavopiridol induces cellular FLICE-inhibitory protein degradation by the proteasome and promotes TRAIL-induced early signaling and apoptosis in breast tumor cells Cancer Res 66 8858 8869 1:CAS:528:DC%2BD28XovF2ht7s%3D 16951203
-
(2006)
Cancer Res
, vol.66
, pp. 8858-8869
-
-
Palacios, C.1
Yerbes, R.2
Lopez-Rivas, A.3
-
129
-
-
34250680223
-
Flavopiridol synergizes TRAIL cytotoxicity by downregulation of FLIPL
-
1:CAS:528:DC%2BD2sXmsVOjsr8%3D 17187253
-
TE Fandy DD Ross SD Gore RK Srivastava 2007 Flavopiridol synergizes TRAIL cytotoxicity by downregulation of FLIPL Cancer Chemother Pharmacol 60 313 319 1:CAS:528:DC%2BD2sXmsVOjsr8%3D 17187253
-
(2007)
Cancer Chemother Pharmacol
, vol.60
, pp. 313-319
-
-
Fandy, T.E.1
Ross, D.D.2
Gore, S.D.3
Srivastava, R.K.4
-
130
-
-
0037311226
-
Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-alpha or TNF-related apoptosis-inducing ligand in human cancer cell lines
-
1:CAS:528:DC%2BD3sXosVyisg%3D%3D 12566305
-
DM Kim SY Koo K Jeon MH Kim J Lee CY Hong S Jeong 2003 Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-alpha or TNF-related apoptosis-inducing ligand in human cancer cell lines Cancer Res 63 621 626 1:CAS:528:DC%2BD3sXosVyisg%3D%3D 12566305
-
(2003)
Cancer Res
, vol.63
, pp. 621-626
-
-
Kim, D.M.1
Koo, S.Y.2
Jeon, K.3
Kim, M.H.4
Lee, J.5
Hong, C.Y.6
Jeong, S.7
-
131
-
-
34247109045
-
Natural products as sources of new drugs over the last 25 years
-
1:CAS:528:DC%2BD2sXhvFKrsro%3D 17309302
-
DJ Newman GM Cragg 2007 Natural products as sources of new drugs over the last 25 years J Nat Prod 70 461 477 1:CAS:528:DC%2BD2sXhvFKrsro%3D 17309302
-
(2007)
J Nat Prod
, vol.70
, pp. 461-477
-
-
Newman, D.J.1
Cragg, G.M.2
-
132
-
-
28844492580
-
Chemosensitization and radiosensitization of tumors by plant polyphenols
-
1:CAS:528:DC%2BD2MXhtlWht73M 16356126
-
AK Garg TA Buchholz BB Aggarwal 2005 Chemosensitization and radiosensitization of tumors by plant polyphenols Antioxid Redox Signal 7 1630 1647 1:CAS:528:DC%2BD2MXhtlWht73M 16356126
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1630-1647
-
-
Garg, A.K.1
Buchholz, T.A.2
Aggarwal, B.B.3
-
133
-
-
50249129735
-
Studies on search for bioactive natural products targeting TRAIL signaling leading to tumor cell apoptosis
-
1:CAS:528:DC%2BD1cXhtV2qsLvN 18273883
-
M Ishibashi T Ohtsuki 2008 Studies on search for bioactive natural products targeting TRAIL signaling leading to tumor cell apoptosis Med Res Rev 28 688 714 1:CAS:528:DC%2BD1cXhtV2qsLvN 18273883
-
(2008)
Med Res Rev
, vol.28
, pp. 688-714
-
-
Ishibashi, M.1
Ohtsuki, T.2
-
134
-
-
61449220943
-
Ethanolic extract of propolis (EEP) enhances the apoptosis-inducing potential of TRAIL in cancer cells
-
1:CAS:528:DC%2BD1MXisVWhtbc%3D 19223822
-
E Szliszka ZP Czuba M Domino B Mazur G Zydowicz W Krol 2009 Ethanolic extract of propolis (EEP) enhances the apoptosis-inducing potential of TRAIL in cancer cells Molecules 14 738 754 1:CAS:528:DC%2BD1MXisVWhtbc%3D 19223822
-
(2009)
Molecules
, vol.14
, pp. 738-754
-
-
Szliszka, E.1
Czuba, Z.P.2
Domino, M.3
Mazur, B.4
Zydowicz, G.5
Krol, W.6
-
135
-
-
77951215549
-
Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors
-
1:CAS:528:DC%2BC3cXktFGlt7o%3D 20154087
-
B Sung B Park VR Yadav BB Aggarwal 2010 Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors J Biol Chem 285 11498 11507 1:CAS:528:DC%2BC3cXktFGlt7o%3D 20154087
-
(2010)
J Biol Chem
, vol.285
, pp. 11498-11507
-
-
Sung, B.1
Park, B.2
Yadav, V.R.3
Aggarwal, B.B.4
-
136
-
-
72449169529
-
Synergistic anti-cancer activity by the combination of TRAIL/APO-2L and celastrol
-
1:CAS:528:DC%2BD1MXhsFCiu7rE
-
H Zhu WJ Ding R Wu QJ Weng JS Lou RJ Jin W Lu B Yang QJ He 2010 Synergistic anti-cancer activity by the combination of TRAIL/APO-2L and celastrol Cancer Investig 28 23 32 1:CAS:528:DC%2BD1MXhsFCiu7rE
-
(2010)
Cancer Investig
, vol.28
, pp. 23-32
-
-
Zhu, H.1
Ding, W.J.2
Wu, R.3
Weng, Q.J.4
Lou, J.S.5
Jin, R.J.6
Lu, W.7
Yang, B.8
He, Q.J.9
-
137
-
-
59149087882
-
Suppression of cFLIP by lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells
-
1:CAS:528:DC%2BD1MXhtFOlu78%3D 19176377
-
I Murtaza M Saleem VM Adhami BB Hafeez H Mukhtar 2009 Suppression of cFLIP by lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells Cancer Res 69 1156 1165 1:CAS:528:DC%2BD1MXhtFOlu78%3D 19176377
-
(2009)
Cancer Res
, vol.69
, pp. 1156-1165
-
-
Murtaza, I.1
Saleem, M.2
Adhami, V.M.3
Hafeez, B.B.4
Mukhtar, H.5
-
138
-
-
0033863355
-
Dietary intake and bioavailability of polyphenols
-
1:CAS:528:DC%2BD3cXltl2gsLw%3D 10917926
-
A Scalbert G Williamson 2000 Dietary intake and bioavailability of polyphenols J Nutr 130 2073S 2085S 1:CAS:528:DC%2BD3cXltl2gsLw%3D 10917926
-
(2000)
J Nutr
, vol.130
-
-
Scalbert, A.1
Williamson, G.2
-
140
-
-
74049161626
-
Resveratrol-loaded calcium-pectinate beads: Effects of formulation parameters on drug release and bead characteristics
-
1:CAS:528:DC%2BD1MXhsF2jsLvF 19653272
-
S Das KY Ng 2010 Resveratrol-loaded calcium-pectinate beads: effects of formulation parameters on drug release and bead characteristics J Pharm Sci 99 840 860 1:CAS:528:DC%2BD1MXhsF2jsLvF 19653272
-
(2010)
J Pharm Sci
, vol.99
, pp. 840-860
-
-
Das, S.1
Ng, K.Y.2
-
141
-
-
66149107051
-
Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice
-
1:CAS:528:DC%2BD1MXmslCguro%3D 19326431
-
NK Narayanan D Nargi C Randolph BA Narayanan 2009 Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice Int J Cancer 125 1 8 1:CAS:528:DC%2BD1MXmslCguro%3D 19326431
-
(2009)
Int J Cancer
, vol.125
, pp. 1-8
-
-
Narayanan, N.K.1
Nargi, D.2
Randolph, C.3
Narayanan, B.A.4
-
142
-
-
33646491901
-
Effect of liposome encapsulation of tea catechins on their accumulation in basal cell carcinomas
-
1:CAS:528:DC%2BD28XjvVagur4%3D 16423506
-
JY Fang WR Lee SC Shen YL Huang 2006 Effect of liposome encapsulation of tea catechins on their accumulation in basal cell carcinomas J Dermatol Sci 42 101 109 1:CAS:528:DC%2BD28XjvVagur4%3D 16423506
-
(2006)
J Dermatol Sci
, vol.42
, pp. 101-109
-
-
Fang, J.Y.1
Lee, W.R.2
Shen, S.C.3
Huang, Y.L.4
-
143
-
-
33744795150
-
Liposomal quercetin efficiently suppresses growth of solid tumors in murine models
-
1:CAS:528:DC%2BD28Xks1Chsrw%3D 16707620
-
ZP Yuan LJ Chen LY Fan MH Tang GL Yang HS Yang XB Du GQ Wang WX Yao QM Zhao B Ye R Wang P Diao W Zhang HB Wu X Zhao YQ Wei 2006 Liposomal quercetin efficiently suppresses growth of solid tumors in murine models Clin Cancer Res 12 3193 3199 1:CAS:528:DC%2BD28Xks1Chsrw%3D 16707620
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3193-3199
-
-
Yuan, Z.P.1
Chen, L.J.2
Fan, L.Y.3
Tang, M.H.4
Yang, G.L.5
Yang, H.S.6
Du, X.B.7
Wang, G.Q.8
Yao, W.X.9
Zhao, Q.M.10
Ye, B.11
Wang, R.12
Diao, P.13
Zhang, W.14
Wu, H.B.15
Zhao, X.16
Wei, Y.Q.17
-
144
-
-
44349192682
-
Delivery of resveratrol, a red wine polyphenol, from solutions and hydrogels via the skin
-
1:CAS:528:DC%2BD1cXotF2mt7c%3D 18451526
-
CF Hung YK Lin ZR Huang JY Fang 2008 Delivery of resveratrol, a red wine polyphenol, from solutions and hydrogels via the skin Biol Pharm Bull 31 955 962 1:CAS:528:DC%2BD1cXotF2mt7c%3D 18451526
-
(2008)
Biol Pharm Bull
, vol.31
, pp. 955-962
-
-
Hung, C.F.1
Lin, Y.K.2
Huang, Z.R.3
Fang, J.Y.4
|