-
1
-
-
0000719887
-
Status of the National Cancer Institute preclinical antitumor drug discovery screen: Implications for selection of new agents for clinical trial
-
V. T. De Vita, Jr., S. Hellman, and S. A. Rosenberg (eds.), Philadelphia: Lippincott
-
Boyd, M. R. Status of the National Cancer Institute preclinical antitumor drug discovery screen: implications for selection of new agents for clinical trial. In: V. T. De Vita, Jr., S. Hellman, and S. A. Rosenberg (eds.), Cancer: Principles and Practice of Oncology Update, Vol. 3, No. 10, pp. 1-12, Philadelphia: Lippincott, 1989.
-
(1989)
Cancer: Principles and Practice of Oncology Update
, vol.3
, Issue.10
, pp. 1-12
-
-
Boyd, M.R.1
-
2
-
-
0025775062
-
Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines
-
Monks, A., Scudiero, D., Hose, C., Langley, J., Cronise, P., Vaigro-Wolff, A., Gray-Goodrich, M., Campbell, H., Skehan, P., Shoemaker, R., Paull, K., Vistica, D., Mayo, J., and Boyd, M. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J. Natl. Cancer Inst., 83: 757-766, 1991.
-
(1991)
J. Natl. Cancer Inst.
, vol.83
, pp. 757-766
-
-
Monks, A.1
Scudiero, D.2
Hose, C.3
Langley, J.4
Cronise, P.5
Vaigro-Wolff, A.6
Gray-Goodrich, M.7
Campbell, H.8
Skehan, P.9
Shoemaker, R.10
Paull, K.11
Vistica, D.12
Mayo, J.13
Boyd, M.14
-
3
-
-
0001461174
-
Cancer drug discovery and development
-
V. T. Rosenberg, S. Hellman, and S. Rosenberg (eds.). Philadelphia: Lippincott
-
Grever, M. R., and Chabner, B. A. Cancer drug discovery and development. In: V. T. Rosenberg, S. Hellman, and S. Rosenberg (eds.), Cancer: Principles and Practice of Oncology, Vol. 1, pp. 328-339. Philadelphia: Lippincott, 1992.
-
(1992)
Cancer: Principles and Practice of Oncology
, vol.1
, pp. 328-339
-
-
Grever, M.R.1
Chabner, B.A.2
-
4
-
-
1842282448
-
Studies in tumor cell biology
-
E. Boven and B. Winograd (eds.). Boca Raton, FL: CRC Press
-
Langdon, P. S., and Smyth, J. F. Studies in tumor cell biology. In: E. Boven and B. Winograd (eds.), The Nude Mice in Oncology Research, pp. 104-116. Boca Raton, FL: CRC Press, 1991.
-
(1991)
The Nude Mice in Oncology Research
, pp. 104-116
-
-
Langdon, P.S.1
Smyth, J.F.2
-
5
-
-
0000378255
-
Combined in vitro/in vivo test procedure with human tumor xenografts for new drug development
-
Fiebig, H. H., Berger, D. P., Dengler, W. A., Wallbrecher, E., and Winterhalter, B. R. Combined in vitro/in vivo test procedure with human tumor xenografts for new drug development. Contrib. Oncol., 42: 321-351, 1992.
-
(1992)
Contrib. Oncol.
, vol.42
, pp. 321-351
-
-
Fiebig, H.H.1
Berger, D.P.2
Dengler, W.A.3
Wallbrecher, E.4
Winterhalter, B.R.5
-
6
-
-
0002634965
-
Comparison of tumor response in nude mice and in the patients
-
B. Winograd, M. J. Peckham, and H. M. Pinedo (eds.). Berlin: Springer Verlag
-
Fiebig, H. H. Comparison of tumor response in nude mice and in the patients. In: B. Winograd, M. J. Peckham, and H. M. Pinedo (eds.), Human Tumor Xenografts in Anticancer Drug Development, pp. 25-30. Berlin: Springer Verlag, 1983.
-
(1983)
Human Tumor Xenografts in Anticancer Drug Development
, pp. 25-30
-
-
Fiebig, H.H.1
-
7
-
-
0023183683
-
Colony assay with human tumor xenografts, murine tumors and human bone marrow. Potential for anticancer drug development
-
Fiebig, H. H., Schmid, J. R., Bieser, W., Henss, H., and Lohr, G. W. Colony assay with human tumor xenografts, murine tumors and human bone marrow. Potential for anticancer drug development. Eur. J. Cancer, 23: 937-948, 1987.
-
(1987)
Eur. J. Cancer
, vol.23
, pp. 937-948
-
-
Fiebig, H.H.1
Schmid, J.R.2
Bieser, W.3
Henss, H.4
Lohr, G.W.5
-
8
-
-
0023924162
-
An anti-inflammatory cum immunomodulatory piperidinylbenzopyranone from Dysoxylum binectariferum: Isolation, structure and total synthesis
-
Naik, R. G., Kattige, S. L., Bhat, S. V., Alreja, B., de Souza, N. J., and Rupp, R. H. An anti-inflammatory cum immunomodulatory piperidinylbenzopyranone from Dysoxylum binectariferum: isolation, structure and total synthesis. Tetrahedron, 44: 2081-2086, 1988.
-
(1988)
Tetrahedron
, vol.44
, pp. 2081-2086
-
-
Naik, R.G.1
Kattige, S.L.2
Bhat, S.V.3
Alreja, B.4
De Souza, N.J.5
Rupp, R.H.6
-
9
-
-
1842279522
-
-
(Hoechst A. G.) European patent EP366061. Japanese patent JP90178225. German patent DE3836676. Vol. 2, May 1990
-
Naik, R. G. (Hoechst A. G.) European patent EP366061. Japanese patent JP90178225. German patent DE3836676. Vol. 2, May 1990.
-
-
-
Naik, R.G.1
-
11
-
-
0001207108
-
The change in research for the therapy of tumors
-
Sedlacek, H. H., Hoffmann, D., Czech, J., Cenek, K., Seemann, G., Güssow, D., and Bosslet, K. The change in research for the therapy of tumors. Chimia, 45: 311-316, 1991.
-
(1991)
Chimia
, vol.45
, pp. 311-316
-
-
Sedlacek, H.H.1
Hoffmann, D.2
Czech, J.3
Cenek, K.4
Seemann, G.5
Güssow, D.6
Bosslet, K.7
-
12
-
-
0026731522
-
Differential inhibition of human squamous cell carcinoma, gliosarcoma and embryonic fibroblast-like lung cells in culture by plant flavonoids
-
Kandaswami, C., Perkins, E., Drzewiecki, G., Soloniuk, D. S., and Middleton, E., Jr. Differential inhibition of human squamous cell carcinoma, gliosarcoma and embryonic fibroblast-like lung cells in culture by plant flavonoids. Anticancer Drugs, 3: 525-530, 1992.
-
(1992)
Anticancer Drugs
, vol.3
, pp. 525-530
-
-
Kandaswami, C.1
Perkins, E.2
Drzewiecki, G.3
Soloniuk, D.S.4
Middleton Jr., E.5
-
13
-
-
0026075305
-
Use and specificity of genistein as inhibitor of protein tyrosine kinases
-
Akiyama, T., and Ogawara, H. Use and specificity of genistein as inhibitor of protein tyrosine kinases. Methods Enzymol., 201: 362-370, 1991.
-
(1991)
Methods Enzymol.
, vol.201
, pp. 362-370
-
-
Akiyama, T.1
Ogawara, H.2
-
14
-
-
0016821736
-
The effect of flavonoids on aerobic glycolysis and growth of tumor cells
-
Suolinna, E. M., Buchsbaum, R. N., and Racker, E. The effect of flavonoids on aerobic glycolysis and growth of tumor cells. Cancer Res., 35: 1865-1872, 1975.
-
(1975)
Cancer Res.
, vol.35
, pp. 1865-1872
-
-
Suolinna, E.M.1
Buchsbaum, R.N.2
Racker, E.3
-
15
-
-
0026454471
-
Protein-tyrosine kinase inhibition: Mechanism based discovery of antitumor agents
-
Chang, C. J., and Geahlen, R. L. Protein-tyrosine kinase inhibition: mechanism based discovery of antitumor agents. J. Nat. Prod., 55: 1529-1560, 1992.
-
(1992)
J. Nat. Prod.
, vol.55
, pp. 1529-1560
-
-
Chang, C.J.1
Geahlen, R.L.2
-
16
-
-
0023897154
-
Differential effects of flavonoids as inhibitors of tyrosine protein kinases and serine/threonine protein kinases
-
Hagiwara, M., Inoue, S., Tanaka, T., Nunoki, K., Ito, M., and Hidaka, H. Differential effects of flavonoids as inhibitors of tyrosine protein kinases and serine/threonine protein kinases. Biochem. Pharmacol., 37: 2987-2992, 1988.
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 2987-2992
-
-
Hagiwara, M.1
Inoue, S.2
Tanaka, T.3
Nunoki, K.4
Ito, M.5
Hidaka, H.6
-
17
-
-
0025239010
-
Enhancement of the antiproliferative activity of cis-diaminedichloroplatinum(II) by quercetin
-
Hofmann, J., Fiebig, H. H., Winterhalter, B. R., Berger, D. P., and Grunicke, H. Enhancement of the antiproliferative activity of cis-diaminedichloroplatinum(II) by quercetin. Int. J. Cancer, 45: 536-539, 1990.
-
(1990)
Int. J. Cancer
, vol.45
, pp. 536-539
-
-
Hofmann, J.1
Fiebig, H.H.2
Winterhalter, B.R.3
Berger, D.P.4
Grunicke, H.5
-
18
-
-
0023664272
-
Genistein, a specific inhibitor of tyrosine specific protein kinases
-
Akiyama, T., Ishida, J., Nakagawa, S., Ogawara, H., Watanabe, S., Itoh, N., Shibuya, M., and Fukami, Y. Genistein, a specific inhibitor of tyrosine specific protein kinases. J. Biol. Chem., 262: 5592-5595, 1987.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 5592-5595
-
-
Akiyama, T.1
Ishida, J.2
Nakagawa, S.3
Ogawara, H.4
Watanabe, S.5
Itoh, N.6
Shibuya, M.7
Fukami, Y.8
-
19
-
-
0027433237
-
cdc2 kinase by the flavone L86-8275 in breast carcinoma cells
-
cdc2 kinase by the flavone L86-8275 in breast carcinoma cells. Biochem. Pharmacol., 46: 1831-1840, 1993.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 1831-1840
-
-
Worland, P.1
Kaur, G.2
Stettler-Stevenson, M.3
Sebers, S.4
Sartor, O.5
Sausville, E.A.6
-
20
-
-
0028176485
-
Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275
-
Losiewicz, M. D., Carlson, B. A., Kaur, G., Sausville, E. A., and Worland, P. J. Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275. Biochem. Biophys. Res. Commun., 207: 589-595, 1994.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.207
, pp. 589-595
-
-
Losiewicz, M.D.1
Carlson, B.A.2
Kaur, G.3
Sausville, E.A.4
Worland, P.J.5
-
21
-
-
0002097692
-
Inhibition of CDK2 by flavopiridol and structural analogs
-
Losiewicz, M. D., Carlson, B. A., Sausville, E. A., Naik, R. G., Narayanan, V. L., and Worland, P. J. Inhibition of CDK2 by flavopiridol and structural analogs. Proc. Am. Assoc. Cancer Res., 36: 35, 1995.
-
(1995)
Proc. Am. Assoc. Cancer Res.
, vol.36
, pp. 35
-
-
Losiewicz, M.D.1
Carlson, B.A.2
Sausville, E.A.3
Naik, R.G.4
Narayanan, V.L.5
Worland, P.J.6
-
23
-
-
0028171292
-
1 phase progression: Cycling on cue
-
1 phase progression: cycling on cue. Cell, 79: 551-555, 1994.
-
(1994)
Cell
, vol.79
, pp. 551-555
-
-
Sherr, C.J.1
-
24
-
-
0026452974
-
Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275
-
Kaur, G., Stettler-Stevenson, M., Sebers, S., Worland, P., Sedlacek, H., Myers, C., Czech, J., Naik, R., and Sausville, E. Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275. J. Natl. Cancer Inst., 84: 1736-1740, 1992.
-
(1992)
J. Natl. Cancer Inst.
, vol.84
, pp. 1736-1740
-
-
Kaur, G.1
Stettler-Stevenson, M.2
Sebers, S.3
Worland, P.4
Sedlacek, H.5
Myers, C.6
Czech, J.7
Naik, R.8
Sausville, E.9
-
25
-
-
0021681603
-
Development and characterization of 51 human tumor models for large bowel, stomach and esophageal cancers
-
Fiebig, H. H., Widmer, K. H., Fiedler, L., Wittekind, C., and Löhr, G. W. Development and characterization of 51 human tumor models for large bowel, stomach and esophageal cancers. Dig. Surg., 1: 225-235, 1984.
-
(1984)
Dig. Surg.
, vol.1
, pp. 225-235
-
-
Fiebig, H.H.1
Widmer, K.H.2
Fiedler, L.3
Wittekind, C.4
Löhr, G.W.5
-
26
-
-
0001869180
-
Establishment and characterization of human tumor xenografts in thymus aplastic nude mice
-
Berger, D. P., Winterhalter, B. R., and Fiebig, H. H. Establishment and characterization of human tumor xenografts in thymus aplastic nude mice. Contrib. Oncol., 42: 23-46, 1992.
-
(1992)
Contrib. Oncol.
, vol.42
, pp. 23-46
-
-
Berger, D.P.1
Winterhalter, B.R.2
Fiebig, H.H.3
-
27
-
-
0020620268
-
Carcinoembryonic antigen (CEA) in human colorectal cancers growing subcutaneously in nude mice
-
Fiebig, H. H., and Von Kleist, S. Carcinoembryonic antigen (CEA) in human colorectal cancers growing subcutaneously in nude mice. J. Cancer Res. Clin. Oncol., 105: 238-242, 1983.
-
(1983)
J. Cancer Res. Clin. Oncol.
, vol.105
, pp. 238-242
-
-
Fiebig, H.H.1
Von Kleist, S.2
-
28
-
-
26344433734
-
Immunohistochemical characterization of human tumor xenografts established in nude mice
-
Furtwängler, I., Fiebig, H. H., Berger, D. P., and Wittekind, C. Immunohistochemical characterization of human tumor xenografts established in nude mice. Contrib. Oncol., 42: 148-151, 1992.
-
(1992)
Contrib. Oncol.
, vol.42
, pp. 148-151
-
-
Furtwängler, I.1
Fiebig, H.H.2
Berger, D.P.3
Wittekind, C.4
-
29
-
-
0010233533
-
Preclinical phase II trials
-
E. Boven and W. Winograd (eds.). Boca Raton, FL: CRC Press
-
Fiebig, H. H., and Berger, D. P. Preclinical phase II trials. In: E. Boven and W. Winograd (eds.). The Nude Mouse in Oncology Research, pp. 317-326. Boca Raton, FL: CRC Press, 1991.
-
(1991)
The Nude Mouse in Oncology Research
, pp. 317-326
-
-
Fiebig, H.H.1
Berger, D.P.2
-
30
-
-
1542488335
-
Chemotherapy: Conventional agents
-
E. Boven and W. Winograd (eds.). Boca Raton, FL: CRC Press
-
Berger, D. P., Winterhalter, B. R., and Fiebig, H. H. Chemotherapy: conventional agents. In: E. Boven and W. Winograd (eds.), The Nude Mouse in Oncology Research, pp. 165-184. Boca Raton, FL: CRC Press, 1991.
-
(1991)
The Nude Mouse in Oncology Research
, pp. 165-184
-
-
Berger, D.P.1
Winterhalter, B.R.2
Fiebig, H.H.3
-
31
-
-
1842348555
-
Characterization of 53 human tumor xenografts by polymorphic enzyme analysis
-
Bender, K., Steiert, A., Berger, P., and Fiebig, H. H. Characterization of 53 human tumor xenografts by polymorphic enzyme analysis. Contrib. Oncol., 42: 87-97, 1992.
-
(1992)
Contrib. Oncol.
, vol.42
, pp. 87-97
-
-
Bender, K.1
Steiert, A.2
Berger, P.3
Fiebig, H.H.4
-
32
-
-
0022455096
-
DNA stemline heterogeneity in colorectal cancer
-
Hiddemann, W., Von Bassewitz, D. B., Kleinemeir, H. J., Schulte-Brochterbeck, E., Hauss, J., Lingemann, B., Büchner, T., and Grundmann, E. DNA stemline heterogeneity in colorectal cancer. Cancer (Phila.), 58: 258-263, 1986.
-
(1986)
Cancer (Phila.)
, vol.58
, pp. 258-263
-
-
Hiddemann, W.1
Von Bassewitz, D.B.2
Kleinemeir, H.J.3
Schulte-Brochterbeck, E.4
Hauss, J.5
Lingemann, B.6
Büchner, T.7
Grundmann, E.8
-
33
-
-
0017785769
-
Primary bioassay of human tumor stem cells
-
Hamburger, A. W., and Salmon, S. E. Primary bioassay of human tumor stem cells. Science (Washington DC), 197: 461-463, 1977.
-
(1977)
Science (Washington DC)
, vol.197
, pp. 461-463
-
-
Hamburger, A.W.1
Salmon, S.E.2
-
34
-
-
0023196515
-
In vitro predictive testing: The sulfonamide era
-
Von Hoff, D. D. In vitro predictive testing: the sulfonamide era. Int. J. Cell Cloning, 5: 179-190, 1987.
-
(1987)
Int. J. Cell Cloning
, vol.5
, pp. 179-190
-
-
Von Hoff, D.D.1
-
35
-
-
0025253853
-
Correlation of drug response in patients and in the clonogenic assay with solid human tumor xenografts
-
Scholz, C. C., Berger, D. P., Winterhalter, B. R., Henβ, H., and Fiebig, H. H. Correlation of drug response in patients and in the clonogenic assay with solid human tumor xenografts. Eur. J. Cancer, 26: 901-905, 1990.
-
(1990)
Eur. J. Cancer
, vol.26
, pp. 901-905
-
-
Scholz, C.C.1
Berger, D.P.2
Winterhalter, B.R.3
Hen, H.4
Fiebig, H.H.5
-
36
-
-
0025127694
-
The clonogenic assay with human tumor xenografts: Evaluation, predictive value and application for drug screening
-
Berger, D. P., Henβ, H., Winterhalter, B. R., and Fiebig, H. H. The clonogenic assay with human tumor xenografts: evaluation, predictive value and application for drug screening. Ann. Oncol., 1: 333-341, 1990.
-
(1990)
Ann. Oncol.
, vol.1
, pp. 333-341
-
-
Berger, D.P.1
Hen, H.2
Winterhalter, B.R.3
Fiebig, H.H.4
-
37
-
-
0024453108
-
Inhibition of protein tyrosine kinase activity by flavonoids and related compounds
-
Geahlen, R. L., Koonchanock, N. M., and McLaughlin, J. L. Inhibition of protein tyrosine kinase activity by flavonoids and related compounds. J. Nat. Prod., 52: 982-986, 1989.
-
(1989)
J. Nat. Prod.
, vol.52
, pp. 982-986
-
-
Geahlen, R.L.1
Koonchanock, N.M.2
McLaughlin, J.L.3
-
39
-
-
0027717617
-
P21 is a universal inhibitor of cyclin kinases
-
Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R., and Beach, D. p21 is a universal inhibitor of cyclin kinases. Nature (Lond.), 366: 701-704, 1993.
-
(1993)
Nature (Lond.)
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
40
-
-
0028128954
-
Differential expression and regulation of cyclin D1 protein in normal and tumor human cells: Association with CDK4 is required for cyclin D1 function in G1 progression
-
Tam, S. W., Theodoras, A. M., Shay, J. W., Draetta, G. F., and Pagano, M. Differential expression and regulation of cyclin D1 protein in normal and tumor human cells: association with CDK4 is required for cyclin D1 function in G1 progression. Oncogene, 9: 2663-2674, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 2663-2674
-
-
Tam, S.W.1
Theodoras, A.M.2
Shay, J.W.3
Draetta, G.F.4
Pagano, M.5
-
41
-
-
0028917771
-
Antitumoral activity of the flavone L86-8275
-
Czech, J., Hoffmann, D., Naik, R., and Sedlacek, H. H. Antitumoral activity of the flavone L86-8275. Int. J. Oncol., 6: 31-36, 1995.
-
(1995)
Int. J. Oncol.
, vol.6
, pp. 31-36
-
-
Czech, J.1
Hoffmann, D.2
Naik, R.3
Sedlacek, H.H.4
-
42
-
-
0021316234
-
Carcinoma of the prostate: The therapeutic dilemma
-
Paulson, D. F. Carcinoma of the prostate: the therapeutic dilemma. Annu. Rev. Med., 35: 341-372, 1984.
-
(1984)
Annu. Rev. Med.
, vol.35
, pp. 341-372
-
-
Paulson, D.F.1
-
43
-
-
0025974356
-
Carcinoma of the prostate
-
Gittes, R. F. Carcinoma of the prostate. N. Engl. J. Med., 324: 236-245, 1991.
-
(1991)
N. Engl. J. Med.
, vol.324
, pp. 236-245
-
-
Gittes, R.F.1
|