Induction of apoptosis in human breast adenocarcinoma MCF-7 cells by prodelphinidin B-2 3,3′-di-O-gallate from Myrica rubra via Fas-mediated pathway

Journal of Pharmacy and Pharmacology

Volumn 56, Issue 11, 2004, Pages 1399-1406

  Kuo, Po Lin ^a   Hsu, Ya Ling ^b   Lin, Ta Chen ^c   Lin, Liang Tzung ^d   Lin, Chun Ching ^b  

^a CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c Ta Jen Institute of Technology   (Taiwan)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; FAS LIGAND; MYRICA RUBRA EXTRACT; PLANT EXTRACT; PROANTHOCYANIDIN DERIVATIVE; PRODELPHINIDIN B 2 3,3' DI O GALLATE; PROTEIN P21; PROTEIN P53; TANNIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; BARK; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CELL ASSAY; CELL CYCLE; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MITOSIS INHIBITION; MYRICA RUBRA; MYRICACEAE; PROTEIN EXPRESSION;

ADENOCARCINOMA; ANTHOCYANINS; ANTIGENS, CD95; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; FAS LIGAND PROTEIN; FEMALE; HUMANS; MEMBRANE GLYCOPROTEINS; MYRICA; PHYTOTHERAPY; PLANT EXTRACTS; TEA; TUMOR CELLS, CULTURED;

EID: 8144229635     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357044625     Document Type: Article

References (38)

1. Cheng, H. Y., Lin, T. C., Ishimaru, K., Yang, C. M., Wang, K. C., Lin, C. C. (2003) In vitro antiviral activity of prodelphinidin B-2 3,3′-di-O-gallate from Myrica rubra. Planta Med. 69: 953-956
2. Chopin, V., Toillon, R. A., Jouy, N., Le Bourhis, X. (2002) Sodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cells. Br. J. Pharmacol. 135: 79-86
3. Dulic, V., Kaufmann, W. K., Wilson, S. J., Tlsty, T. D., Lees, E., Harper, J. W., Elledge, S. J., Reed, S. I. (1994) p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76: 1013-1023
4. El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., Vogelstein, B. (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75: 817-825
5. Evan, G. I., Vousden, K. H. (2001) Proliferation, cell cycle and apoptosis in cancer. Nature 411: 342-348
6. Glick, R. D., Swendeman, S. L., Coffey, D. C., Rifkind, R. A., Marks, P. A., Richon, V. M., La Quaglia, M. P. (1999) Hybrid polar histone deacetylase inhibitor induces apoptosis and CD95/CD95 ligand expression in human neuroblastoma. Cancer Res. 59: 4392-4399
7. Gu, Y., Turck, C. W., Morgan, D. O. (1993) Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 366: 707-710
8. Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K., Elledge, S. J. (1993) The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816
9. Hengartner, M. O. (2000) The biochemistry of apoptosis. Nature 407: 770-776
10. Igney, F. H., Krammer, P. H. (2002) Death and anti-death: tumour resistance to apoptosis. Nat. Rev. Cancer 2: 277-288
11. Juo, P., Kuo, C. J., Yuan, J., Blenis, J. (1998) Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade. Curr. Biol. 8: 1001-1008
12. Kamsteeg, M., Rutherford, T., Sapi, E., Hanczaruk, B., Shahabi, S., Flick, M., Brown, D., Mor, G. (2003) Phenoxodiol-an isoflavone analog-induces apoptosis in chemoresistant ovarian cancer cells. Oncogene 22: 2611-2620
13. Kayagaki, N., Kawasaki, A., Ebata, T., Ohmoto, H., Ikeda, S., Inoue, S., Yoshino, K., Okumura, K., Yagita, H. (1995) Metalloproteinase-mediated release of human Fas ligand. J. Exp. Med. 182: 1777-1783
14. Kemp, C. J., Sun, S., Gurley, K. E. (2001) p53 induction and apoptosis in response to radio- and chemotherapy in vivo is tumor-type-dependent. Cancer Res. 61: 327-332
15. Landowski, T. H., Gleason-Guzman, M. C., Dalton, W. S. (1997) Selection for drug resistance results in resistance to Fas-mediated apoptosis. Blood 89: 1854-1861
16. Macleod, K. F., Sherry, N., Hannon, G., Beach, D., Tokino, T., Kinzler, K., Vogelstein, B., Jacks, T. (1995) p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev. 9: 935-944
17. Matsuda, H., Yamazaki, M., Matsuo, K., Asanuma, Y., Kubo, M. (2001) Anti-androgenic activity of Myricae Cortex-isolation of active constituents from bark of Myrica rubra. Biol. Pharm. Bull. 24: 259-263
18. Matsuda, H., Morikawa, T., Tao, J., Ueda, K., Yoshikawa, M. (2002) Bioactive constituents of Chinese natural medicines. VII. Inhibitors of degranulation in RBL-2H3 cells and absolute stereostructures of three new diarylheptanoid glycosides from the bark of Myrica rubra. Chem. Pharm. Bull. (Tokyo) 50: 208-215
19. May, P., May, E. (1999) Twenty years of p53 research: structural and functional aspects of the p53 protein. Oncogene 18: 7621-7636
20. Michieli, P., Chedid, M., Lin, D., Pierce, J. H., Mercer, E., Givol, D. (1994) Induction of Wafl/CIPl by a p53-independent pathway. Cancer Res. 54: 3391-3395
21. Nagata, S., Golstein, P. (1995) The Fas death factor. Science 267: 1449-1456
22. Nonaka, G. I., Muta, M., Nishioka, I. (1983) Myricatin, a galloyl flavanonol sulfate and prodelphinidin gallates from Myrica rubra. Phytochemistry 22: 237-241
23. Ohta, S., Sakurai, N., Kamogawa, A., Yaguchi, Y., Inoue, T., Shinoda, M. (1992) Protective effects of the bark of Myrica rubra Sieb. et Zucc. on experimental liver injuries. Yakugaku Zasshi 112: 244-252
24. Plumb, G. W., de Pascual-Teresa, S., Santos-Buelga, C., Rivas-Gonzalo, J. C., Williamson, G. (2002) Antioxidant properties of gallocatechin and prodelphinidins from pomegranate peel. Redox. Rep. 7: 41-46
25. Qian, H., Wang, T., Naumovski, L., Lopez, C. D., Brachmann, P. K. (2002) Groups of p53 target genes involved in specific p53 down-stream effects cluster into different classes of DNA binding sites. Oncogene 21: 7901-7911
26. Reimer, T., Herrnring, C., Koczan, D., Richter, D., Gerber, B., Kabelitz, D., Friese, K., Thiesen, H. J. (2000) FasL:Fas ratio-a prognostic factor in breast carcinomas. Cancer Res. 15: 822-828
27. Sharpless, N. E., DePinho, R. A. (2002) p53: good cop/bad cop. Cell 110: 9-12
28. Sheikh, M. S., Fornace A. J. (2000) Role of p53 family members in apoptosis. J. Cell Physiol. 182: 171-181
29. Sionov, R. V., Haupt, Y. (1999) The cellular response to p53: the decision between life and death. Oncogene 18: 6145-6157
30. Suda, T., Takahashi, T., Golstein, P., Nagata, S. (1993) Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75: 1169-1178
31. Syed, V., Ho, S. M. (2003) Progesterone-induced apoptosis in immortalized normal and malignant human ovarian surface epithelial cells involves enhanced expression of FasL. Oncogene 22: 6883-6890
32. Takechi, M. I., Tanaka, Y., Takehara, M., Nonaka, G. I., Nishioka, I. (1985) Structure and antiherpetic activity among the tannins. Phytochemistry 24: 2245-2250
33. Tao, J., Morikawa, T., Toguchida, I., Ando, S., Matsuda, H., Yoshikawa, M. (2002) Inhibitors of nitric oxide production from the bark of Myrica rubra: structures of new biphenyl type diarylheptanoid glycosides and taraxerane type triterpene. Bioorg. Med. Chem. 10: 4005-4012
34. Toillon, R. A., Descamps, S., Adriaenssens, E., Ricort, J. M., Bernard, D., Boilly, B., Le Bourhis, X. (2002) Normal breast epithelial cells induce apoptosis of breast cancer cells via Fas signaling. Exp. Cell Res. 275: 31-43
35. Vergote, D., Cren-Olive, C., Chopin, V., Toillon, R. A., Rolando, C., Hondermarck, H. & Le Bourhis, X. (2002) (-)-Epigallocatechin (EGC) of green tea induces apoptosis of human breast cancer cells but not of their normal counterparts. Breast Cancer Res. Treat. 76: 195-201
36. Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R., Beach, D. (1993) p21 is a universal inhibitor of cyclin kinases. Nature 366: 701-704
37. Yang, L. L., Chang, C. C., Chen, L. G., Wang, C. C. (2003) Antitumor principle constituents of Myrica rubra Var. acuminata. J. Agric. Food Chem. 51: 2974-2979
38. Yu, W., Israel, K., Liao, Q. Y., Aldaz, C. M., Sanders, B. G., Kline, K. (1999) Vitamin E succinate (VES) induces Fas sensitivity in human breast cancer cells: role for Mr 43,000 Fas in VES-triggered apoptosis. Cancer Res. 59: 953-961