A rice bran polyphenol, cycloartenyl ferulate, elicits apoptosis in human colorectal adenocarcinoma SW480 and sensitizes metastatic SW620 cells to TRAIL-induced apoptosis

Biochemical Pharmacology

Volumn 77, Issue 9, 2009, Pages 1487-1496

  Kong, Carrie K L ^a   Lam, W S ^a   Chiu, Lawrence C M ^a   Ooi, Vincent E C ^a   Sun, Samuel S M ^a   Wong, Yum Shing ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; Colorectal cancer; Cycloartenyl ferulate; Rice bran; TRAIL

Indexed keywords

CASPASE 3; CASPASE 8; CYCLOARTENYL FERULATE; CYTOCHROME C; DEATH RECEPTOR 4; DEATH RECEPTOR 5; POLYPHENOL; PROTEIN BAK; PROTEIN BCL 2; PROTEIN BID; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER REGRESSION; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENZYME ACTIVATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MALE; METASTASIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RICE BRAN; TUMOR XENOGRAFT; UPREGULATION;

ADENOCARCINOMA; ANALGESICS; ANIMALS; APOPTOSIS; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL SURVIVAL; COLON; COLORECTAL NEOPLASMS; COUMARIC ACIDS; DRUG SYNERGISM; FLAVONOIDS; HUMANS; MALE; MICE; MICE, NUDE; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; ORYZA SATIVA; PHENOLS; PROTEIN BINDING; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT PROTEINS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 63149175753     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.02.008     Document Type: Article

References (42)

1. Poon M.A., Oconnell M.J., Moertel C.G., Wieand H.S., Cullinan S.A., Everson L.K., et al. Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma. J Clin Oncol 7 (1989) 1407-1418
2. Poon M.A., O'Connell M.J., Wieand H.S., Krook J.E., Gerstner J.B., Tschetter L.K., et al. Biochemical modulation of fluorouracil with leucovorin: confirmatory evidence of improved therapeutic efficacy in advanced colorectal cancer. J Clin Oncol 9 (1991) 1967-1972
3. Ferrara N., Hillan K.J., Gerber H., and Novotny W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 3 (2004) 391-400
4. Caldwell B., Aldington S., Weatherall M., Shirtcliffe P., and Beasley R. Risk of cardiovascular events and celecoxib: a systematic review and meta-analysis. J R Soc Med 99 (2006) 132-140
5. Chatenoud L., Tavani A., Vecchia C.L., Jacobs D.R., Neger E., Levi F., et al. Whole grain food intake and cancer risk. Int J Cancer 77 (1998) 24-28
6. Steinmetz K.A., and Potter J.D. Vegetables, fruit and cancer. I. Epidemiology. Cancer Causes Control 2 (1991) 325-357
7. Jariwalla R.J. Rice-bran products: phytonutrients with potential applications in preventive and clinical medicine. Drugs Exp Clin Res 27 (2001) 17-26
8. Glade M.J. Food, nutrition, and the prevention of cancer: a global perspective. American Institute for Cancer Research/World Cancer Research Fund, American Institute for Cancer Research, 1997. Nutrition 15 (1999) 523-526
9. Yasukawa K., Akihisa T., Kimura Y., Tamura T., and Takido M. Inhibitory effect of cycloartenol ferulate, a component of rice bran, on tumor promotion in two-stage carcinogenesis in mouse skin. Biol Pharm Bull 21 (1998) 1072-1076
10. Nagasaka R., Chotimarkorn C., Shafiqul I.M., Hori M., Ozaki H., and Ushio H. Anti-inflammatory effects of hydroxycinnamic acid derivatives. Biochem Biophys Res Commun 358 (2007) 615-619
11. Gura T. How TRAIL kills cancer cells, but not normal cells. Science 277 (1997) 768
12. Fesik S.W. Promoting apoptosis as a strategy for cancer drug discovery. Nat Rev Cancer 5 (2005) 876-885
13. Chou T.C., and Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22 (1984) 27-55
14. Gross A., McDonnell J.M., and Krosmeyer S.J. Bcl-2 family members and the mitochondria in apoptosis. Genes Dev 13 (1999) 1899-1911
15. Rodriguez J., and Lazebnik Y. Caspase-9 and APAF-1 form an active holoenzyme. Genes Dev 13 (1999) 3179-3184
16. Srinivasula S.M., Hegde R., Saleh A., Datta P., Shiozaki E., Chai J., et al. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature 410 (2001) 112-116
17. Slavin J., Jacobs D., and Marquart L. Whole grain consumption and chronic disease: protective mechanisms. Nutr Cancer 27 (1997) 14-21
18. Verschoyle R.D., Greaves P., Cai H., Edwards R.E., Steward W.P., and Gescher A.J. Evaluation of the cancer chemopreventive efficacy of rice bran in genetic mouse models of breast, prostate and intestinal carcinogenesis. Br J Cancer 96 (2007) 248-254
19. Hudson E.A., Dinh P.A., Kokubun T., Simmonds M.S., and Gescher A. Characterization of potentially chemopreventive phenols in extracts of brown rice that inhibit the growth of human breast and colon cancer cells. Cancer Epidemiol Biomarkers Prev 9 (2000) 1163-1170
20. Sugano M., Koba K., and Tsuji E. Health benefits of rice bran oil. Anticancer Res 19 (1999) 3651
21. Jin Z., McDonald III E.R., Dicker D.T., and El-Deiry W.S. Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis. J Biol Chem 279 (2004) 35829-35839
22. Levine A.J. p53, the cellular gatekeeper for growth and division. Cell 88 (1997) 323-331
23. Velculescu V.E. Biological and clinical importance of the p53 tumor suppressor gene. Clin Chem 42 (1996) 858-868
24. Bolt M.W., Card J.W., Racz W.J., Brien J.F., and Massey T.E. Disruption of mitochondrial function and cellular ATP levels by amiodarone and N-desethylamiodarone in initiation of amiodarone-induced pulmonary cytotoxicity. J Pharmacol Exp Ther 298 (2001) 1280-1289
25. Mingatto F.E., Rodrigues T., Pigoso A.A., Uyemura S.A., Curti C., and Santos A.C. The critical role of mitochondrial energetic impairment in the toxicity of nimesulide to hepatocytes. J Pharmacol Exp Ther 303 (2002) 601-607
26. Rodriguez J., and Lazebnik Y. Caspase-9 and APAF-1 form an active holoenzyme. Genes Development 13 (1999) 3179-3184
27. Schelwies K., Sturm I., Grabowski P., Scherubl H., Schindler I., Hermann S., et al. Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors. Int J Cancer 99 (2002) 589-596
28. Mrozek A., Petrowsky H., Sturm I., Kraus J., Hermann S., Hauptmann S., et al. Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability. Cell Death Differ 10 (2003) 461-467
29. Kluck R.M., Bossy-Wetzel E., Green D.R., and Newmeyer D.D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275 (1997) 1132-1136
30. Adrian C., Creagh E.M., and Martin S.J. Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2. EMBO J 20 (2001) 6627-6636
31. Desagher S., Osen-Sand A., Nicholes A., Eskes R., Montessuit S., Lauper S., et al. Bid-induced conformational change of bax is responsible for mitochondrial cytochrome c release during apoptosis. J Cell Biol 144 (1999) 891-901
32. Eskes R., Desagher S., Antonsson B., and Martinou J.C. Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol Cell Biol 20 (2000) 929-935
33. Jin Z., and El-Deiry W.S. Overview of cell death signaling pathways. Cancer Biol Ther 4 (2005) 139-163
34. Sheikh M.S., and Huang Y. Death receptor as targets of cancer therapeutics. Curr Cancer Drug Targets 4 (2004) 97-104
35. Delmas D., Rébé C., Micheau O., Athias A., Gambert P., Grazide S., et al. Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells. J Biol Chem 278 (2003) 41482-41490
36. Kim K., Fisher M.J., Xu S.Q., and el-Deiry W.S. Molecular determinants of response to TRAIL in killing of normal and cancer cells. Clin Cancer Res 6 (2000) 335-346
37. Mitsiades N., Poulaki V., Mitsiades C., and Tsokos M. Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-relates apoptosis-inducing ligand and express death receptor 4 and death receptor 5. Cancer Res 61 (2001) 2704-2712
38. Kuang A.A., Diehl G.E., Zhang J., and Winoto A. FADD is required for DR4- and DR5-mediated apoptosis: lack of TRAIL-induced apoptosis in FADD-deficient mouse embryonic fibroblasts. J Biol Chem 275 (2000) 25065-25068
39. Hao J.H., Yu M., Liu F.T., Newland A.C., and Jia L. Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells. Cancer Res 64 (2004) 3607-3616
40. Gorlick R., and Bertino J.R. Drug resistance in colon cancer. Semin Oncol 26 (1999) 606-611
41. Yoshida T., Maoka T., Das S.K., Kanazawa K., Horinaka M., Wakada M., et al. Halocynthiaxanthin and peridinin sensitize colon cancer cell lines to tumor necrosis factor-related apoptosis-inducing ligand. Mol Cancer Res 5 (2007) 615-625
42. Psahoulia F.H., Drosopoulos K.G., Doubravska L., Andera L., and Pintzas A. Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts. Mol Cancer Res 6 (2007) 2591-2599