-
1
-
-
0034721509
-
Up-regulation of the lysosomal system in experimental models of neuronal injury: implications for Alzheimer's disease
-
Adamec E., Mohan P.S., Cataldo A.M., Vonsattel J.P., Nixon R.A. Up-regulation of the lysosomal system in experimental models of neuronal injury: implications for Alzheimer's disease. Neuroscience 2000, 100:663-675.
-
(2000)
Neuroscience
, vol.100
, pp. 663-675
-
-
Adamec, E.1
Mohan, P.S.2
Cataldo, A.M.3
Vonsattel, J.P.4
Nixon, R.A.5
-
3
-
-
0037216189
-
β-Amyloid (1-40)-induced apoptosis of cultured cortical neurones involves calpain-mediated cleavage of poly-ADP-ribose polymerase
-
Boland B., Campbell V. β-Amyloid (1-40)-induced apoptosis of cultured cortical neurones involves calpain-mediated cleavage of poly-ADP-ribose polymerase. Neurobiol. Aging 2003, 24:179-186.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 179-186
-
-
Boland, B.1
Campbell, V.2
-
4
-
-
0346850963
-
Aβ-mediated activation of the apoptotic cascade in cultured cortical neurones: a role for cathepsin-L Neurobiol
-
Boland B., Campbell V. Aβ-mediated activation of the apoptotic cascade in cultured cortical neurones: a role for cathepsin-L Neurobiol. Aging 2004, 25:83-91.
-
(2004)
Aging
, vol.25
, pp. 83-91
-
-
Boland, B.1
Campbell, V.2
-
5
-
-
0038529617
-
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion
-
Boya P., Andreau K., Poncet D., Zamzami N., Perfettini J.L., Metivier D., Ojcius D.M., Jaattela M., Kroemer G. Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J. Exp. Med. 2003, 197:1323-1334.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1323-1334
-
-
Boya, P.1
Andreau, K.2
Poncet, D.3
Zamzami, N.4
Perfettini, J.L.5
Metivier, D.6
Ojcius, D.M.7
Jaattela, M.8
Kroemer, G.9
-
6
-
-
0038677510
-
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
-
Boya P., Gonzalez-Polo R.A., Poncet D., Andreau K., Vieira H.L., Roumier T., Perfettini J.L., Kroemer G. Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene 2003, 22:3927-3936.
-
(2003)
Oncogene
, vol.22
, pp. 3927-3936
-
-
Boya, P.1
Gonzalez-Polo, R.A.2
Poncet, D.3
Andreau, K.4
Vieira, H.L.5
Roumier, T.6
Perfettini, J.L.7
Kroemer, G.8
-
7
-
-
0032988381
-
Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak
-
Brunk U.T., Svensson I. Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak. Redox Rep. 1999, 4:3-11.
-
(1999)
Redox Rep.
, vol.4
, pp. 3-11
-
-
Brunk, U.T.1
Svensson, I.2
-
8
-
-
0033955920
-
Probing the cathepsins using a BODIPY FL-pepstatin A: applications in florescence polarization and microscopy
-
Chen C.S., Chen W.N., Zhou M., Arttamangkul S., Haugland R.P. Probing the cathepsins using a BODIPY FL-pepstatin A: applications in florescence polarization and microscopy. J. Biochem. Biophys. Meth. 2000, 42:137-151.
-
(2000)
J. Biochem. Biophys. Meth.
, vol.42
, pp. 137-151
-
-
Chen, C.S.1
Chen, W.N.2
Zhou, M.3
Arttamangkul, S.4
Haugland, R.P.5
-
9
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk J.E., Kuwana T., Bouchier-Hayes L., Droin N.M., Newmeyer D.D., Schuler M., Green D.R. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 2004, 303:1010-1014.
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
10
-
-
33744943247
-
Multiple actions of pifithrin-α on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells A
-
Chua C.C., Liu X., Gao J., Hamdy R.C., Chua B.H.L. Multiple actions of pifithrin-α on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells A. J. Physiol. Heart Circ. Physiol. 2006, 290:H2606-H2613.
-
(2006)
J. Physiol. Heart Circ. Physiol.
, vol.290
-
-
Chua, C.C.1
Liu, X.2
Gao, J.3
Hamdy, R.C.4
Chua, B.H.L.5
-
11
-
-
0035085210
-
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β-peptide
-
Culmsee C., Zhu X., Yu Q.-S., Chan S.L., Camandola S., Guo Z., Greig N.H., Mattson M.P. A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β-peptide. J. Neurochem. 2001, 77:220-228.
-
(2001)
J. Neurochem.
, vol.77
, pp. 220-228
-
-
Culmsee, C.1
Zhu, X.2
Yu, Q.-S.3
Chan, S.L.4
Camandola, S.5
Guo, Z.6
Greig, N.H.7
Mattson, M.P.8
-
12
-
-
0033593230
-
Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xl
-
Finucane D.M., Bossy-Wetzel E., Waterhouse N.J., Cotter T.G., Green D.R. Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xl. J. Biol. Chem. 1999, 274:2225-2233.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2225-2233
-
-
Finucane, D.M.1
Bossy-Wetzel, E.2
Waterhouse, N.J.3
Cotter, T.G.4
Green, D.R.5
-
13
-
-
0038584865
-
A role for c-jun N terminal kinase 1 (JNK1), but not JNK2, in the β-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade in cultured cortical neuron
-
Fogarty M.P., Downer E.J., Campbell V. A role for c-jun N terminal kinase 1 (JNK1), but not JNK2, in the β-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade in cultured cortical neuron. Biochem. J. 2003, 371:789-798.
-
(2003)
Biochem. J.
, vol.371
, pp. 789-798
-
-
Fogarty, M.P.1
Downer, E.J.2
Campbell, V.3
-
14
-
-
0034697299
-
E2F1 mediates death of β-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase-3
-
Giovanni A., Keramaris E., Morris E.J., Hou S.T., O'Hare M., Dyson N., Robertson G.S., Slack R.S., Park D.S. E2F1 mediates death of β-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase-3. J. Biol. Chem. 2000, 275(16):11553-11560.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.16
, pp. 11553-11560
-
-
Giovanni, A.1
Keramaris, E.2
Morris, E.J.3
Hou, S.T.4
O'Hare, M.5
Dyson, N.6
Robertson, G.S.7
Slack, R.S.8
Park, D.S.9
-
15
-
-
0021207461
-
Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein
-
Glenner G.G., Wong C.W. Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem. Biophys. Res. Comm. 1984, 122:1131-1135.
-
(1984)
Biochem. Biophys. Res. Comm.
, vol.122
, pp. 1131-1135
-
-
Glenner, G.G.1
Wong, C.W.2
-
16
-
-
42549128696
-
A role for p53 in the regulation of lysosomal permeability by Δ9-tetrahydrocannabinol in rat cortical neurones: implications for neurodegeneration
-
Gowran A., Campbell V.A. A role for p53 in the regulation of lysosomal permeability by Δ9-tetrahydrocannabinol in rat cortical neurones: implications for neurodegeneration. J. Neurochem. 2008, 105:1513-1524.
-
(2008)
J. Neurochem.
, vol.105
, pp. 1513-1524
-
-
Gowran, A.1
Campbell, V.A.2
-
17
-
-
18144428775
-
Prospective therapeutic applications of p53 inhibitors
-
Gudkov A.V., Komarova E.A. Prospective therapeutic applications of p53 inhibitors. Biochem. Biophys. Res. Commun. 2005, 331:726-736.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.331
, pp. 726-736
-
-
Gudkov, A.V.1
Komarova, E.A.2
-
18
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death
-
Hitami J., Katayama T., Eguchi Y., Kudo T., Taniguchi M., Koyama Y., Manabe T., Yamagishi S., Bando Y., Imaizumi K., Tsujimoto Y., Tohyama M. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death. J. Cell Biol. 2004, 165:347-356.
-
(2004)
J. Cell Biol.
, vol.165
, pp. 347-356
-
-
Hitami, J.1
Katayama, T.2
Eguchi, Y.3
Kudo, T.4
Taniguchi, M.5
Koyama, Y.6
Manabe, T.7
Yamagishi, S.8
Bando, Y.9
Imaizumi, K.10
Tsujimoto, Y.11
Tohyama, M.12
-
19
-
-
0033494227
-
Participation of a cathepsin-L-type protease in the activation of caspase-3
-
Ishisaka R., Utsumi T., Kanno T., Arita K., Katunuma N., Akiyama J., Utsemi K. Participation of a cathepsin-L-type protease in the activation of caspase-3. Cell Struct. Funct. 1999, 24:465-470.
-
(1999)
Cell Struct. Funct.
, vol.24
, pp. 465-470
-
-
Ishisaka, R.1
Utsumi, T.2
Kanno, T.3
Arita, K.4
Katunuma, N.5
Akiyama, J.6
Utsemi, K.7
-
20
-
-
0028169925
-
Visualization of Aβ42 and Aβ40 in senile plaques with end-specific β monoclonals: evidence that an initially deposited species is Aβ42
-
Iwatsubo T., Odaka A., Suzuki N., Mizusawa H., Nukina N., Ihara Y. Visualization of Aβ42 and Aβ40 in senile plaques with end-specific β monoclonals: evidence that an initially deposited species is Aβ42. Neuron 1994, 13:45-53.
-
(1994)
Neuron
, vol.13
, pp. 45-53
-
-
Iwatsubo, T.1
Odaka, A.2
Suzuki, N.3
Mizusawa, H.4
Nukina, N.5
Ihara, Y.6
-
21
-
-
0037077284
-
Apolipoprotein E4 potentiates amyloid β peptide-induced lysosomal leakage and apoptosis in neuronal cells
-
Ji Z.-S., Miranda R.D., Newhouse Y.M., Weisgraber K.H., Hunag Y., Mahley R.W. Apolipoprotein E4 potentiates amyloid β peptide-induced lysosomal leakage and apoptosis in neuronal cells. J. Biol. Chem. 2002, 277:21821-21828.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21821-21828
-
-
Ji, Z.-S.1
Miranda, R.D.2
Newhouse, Y.M.3
Weisgraber, K.H.4
Hunag, Y.5
Mahley, R.W.6
-
22
-
-
33645553416
-
Reactivity of apolipoprotein E4 and β-amyloid: lysosomal stability and neurodegeneration
-
Ji Z.S., Mullendorff K., Cheng I.H., Miranda R.D., Huang Y., Mahley R.W. reactivity of apolipoprotein E4 and β-amyloid: lysosomal stability and neurodegeneration. J. Biol. Chem. 2006, 281(5):2683-2692.
-
(2006)
J. Biol. Chem.
, vol.281
, Issue.5
, pp. 2683-2692
-
-
Ji, Z.S.1
Mullendorff, K.2
Cheng, I.H.3
Miranda, R.D.4
Huang, Y.5
Mahley, R.W.6
-
23
-
-
26244443655
-
Lysosomal membrane permeabilization during apoptosis: involvement of Bax?
-
Kagedal K., Johansson A.C., Johansson U., Heimlich G., Roberg K., Wang N.S., Jurgensmeier J.M., Ollinger K. Lysosomal membrane permeabilization during apoptosis: involvement of Bax?. Int. J. Exp. Pathol. 2005, 86(5):309-321.
-
(2005)
Int. J. Exp. Pathol.
, vol.86
, Issue.5
, pp. 309-321
-
-
Kagedal, K.1
Johansson, A.C.2
Johansson, U.3
Heimlich, G.4
Roberg, K.5
Wang, N.S.6
Jurgensmeier, J.M.7
Ollinger, K.8
-
24
-
-
17144442666
-
Changes of p53 in the brains of patients with Alzheimer's disease.
-
Kitamura Y., Shimohama S., Kamoshima W., Matsuoka Y., Nomura Y., Taniguchi T. Changes of p53 in the brains of patients with Alzheimer's disease. Biochem. Biophys. Res. Commun. 1997, 232:418-421.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.232
, pp. 418-421
-
-
Kitamura, Y.1
Shimohama, S.2
Kamoshima, W.3
Matsuoka, Y.4
Nomura, Y.5
Taniguchi, T.6
-
25
-
-
0033543728
-
A chemical inhibitor of p53 that protects mice from the side effects of cancer
-
Komarov P.G., Komarova E.A., Kondratov R.V., Christov-Tselkov K., Coon J.S., Chernov M.V., Gudkov A.V. A chemical inhibitor of p53 that protects mice from the side effects of cancer. Science 1999, 285:1733-1737.
-
(1999)
Science
, vol.285
, pp. 1733-1737
-
-
Komarov, P.G.1
Komarova, E.A.2
Kondratov, R.V.3
Christov-Tselkov, K.4
Coon, J.S.5
Chernov, M.V.6
Gudkov, A.V.7
-
26
-
-
0037507247
-
P53 inhibior, PFT-alpha can suppress heat shock and glucocorticold signalling pathways
-
Komarova E.A., Neznanov N., Komarov P.G., Gudkov A. p53 inhibior, PFT-alpha can suppress heat shock and glucocorticold signalling pathways. J. Biol. Chem. 2003, 278:15465-15468.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15465-15468
-
-
Komarova, E.A.1
Neznanov, N.2
Komarov, P.G.3
Gudkov, A.4
-
27
-
-
0029823454
-
Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice
-
Laferla F.M., Hall C.K., Ngo L., Jay G. Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice. J. Clin. Invest. 1996, 98:1232-1626.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1232-1626
-
-
Laferla, F.M.1
Hall, C.K.2
Ngo, L.3
Jay, G.4
-
28
-
-
37048999377
-
Adaptor protein LAPF recruits phosphorylated p53 to lysosomes and triggers lysosomal destabilization in apoptosis
-
Lin N., Zheng Y., Chen W., Wang C., Lui X., He W., Xu H., Cao X. Adaptor protein LAPF recruits phosphorylated p53 to lysosomes and triggers lysosomal destabilization in apoptosis. Cancer Res. 2007, 67:11176-11185.
-
(2007)
Cancer Res.
, vol.67
, pp. 11176-11185
-
-
Lin, N.1
Zheng, Y.2
Chen, W.3
Wang, C.4
Lui, X.5
He, W.6
Xu, H.7
Cao, X.8
-
29
-
-
0031044644
-
Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus
-
MacGibbon G.A., Lawlor P.A., Sirimanne E.S., Walton M.R., Connor B., Young D., Williams C., Gluckman P., Faull R.L., Hughes P., Dragunow M. Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus. Brain Res. 1997, 750:223-234.
-
(1997)
Brain Res.
, vol.750
, pp. 223-234
-
-
MacGibbon, G.A.1
Lawlor, P.A.2
Sirimanne, E.S.3
Walton, M.R.4
Connor, B.5
Young, D.6
Williams, C.7
Gluckman, P.8
Faull, R.L.9
Hughes, P.10
Dragunow, M.11
-
30
-
-
0034681208
-
(1-40) in rat cortical synaptosomes and cultured cortical neurones: modulation by the proinflammatory cytokine interleukin-1β
-
(1-40) in rat cortical synaptosomes and cultured cortical neurones: modulation by the proinflammatory cytokine interleukin-1β. J. Biol. Chem. 2000, 275(5):4713-4718.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.5
, pp. 4713-4718
-
-
MacManus, A.1
Ramsden, M.2
Murray, M.3
Pearson, H.A.4
Campbell, V.5
-
31
-
-
0037349289
-
P53 has a direct apoptogenic role at the mitochondria
-
Mihara M., Erster S., Zaika A., Petrenko O., Chittenden T., Pancoska P., Moll U.M. p53 has a direct apoptogenic role at the mitochondria. Mol. Cell 2003, 11:577-590.
-
(2003)
Mol. Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
Moll, U.M.7
-
32
-
-
0028883179
-
Tumour suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T., Reed J.C. Tumour suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995, 80:293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
33
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by β-amyloid
-
Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by β-amyloid. Nature 2000, 403:98-103.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
34
-
-
0029860523
-
Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates Bax expression in human neurons
-
Paradis E., Douillard H., Koutroumanis M., Goodyer C., LeBlanc A. Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates Bax expression in human neurons. J. Neurosci. 1996, 16:7533-7539.
-
(1996)
J. Neurosci.
, vol.16
, pp. 7533-7539
-
-
Paradis, E.1
Douillard, H.2
Koutroumanis, M.3
Goodyer, C.4
LeBlanc, A.5
-
35
-
-
0037336851
-
Caspase gene expression in the brain as a function of the clinical progression in Alzheimer's disease
-
Pompl P.N., Yemul S., Xiang Z., Ho L., Haroutunian V., Purohit D., Mohs R., Pasinetti G.M. Caspase gene expression in the brain as a function of the clinical progression in Alzheimer's disease. Arch. Neurol. 2003, 60:369-376.
-
(2003)
Arch. Neurol.
, vol.60
, pp. 369-376
-
-
Pompl, P.N.1
Yemul, S.2
Xiang, Z.3
Ho, L.4
Haroutunian, V.5
Purohit, D.6
Mohs, R.7
Pasinetti, G.M.8
-
36
-
-
0035206383
-
Mechanisms of p53-dependent apoptosis
-
Schuler M., Green D.R. Mechanisms of p53-dependent apoptosis. Biochem. Soc. Trans. 2001, 29:684-688.
-
(2001)
Biochem. Soc. Trans.
, vol.29
, pp. 684-688
-
-
Schuler, M.1
Green, D.R.2
-
37
-
-
0038168188
-
Calpains mediate p53 activation and neuronal death evoked by DNA damage
-
Sedarous M., Keramaris E., O'Hare M., Melloni E., Slack R.S., Elce J.S., Greer P.A., Park D.S. Calpains mediate p53 activation and neuronal death evoked by DNA damage. J. Biol. Chem. 2003, 278(28):26031-26038.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.28
, pp. 26031-26038
-
-
Sedarous, M.1
Keramaris, E.2
O'Hare, M.3
Melloni, E.4
Slack, R.S.5
Elce, J.S.6
Greer, P.A.7
Park, D.S.8
-
38
-
-
0033601746
-
Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
-
Slee E.A., Harte M.T., Kluck R.M., Wolf B.B., Casiano C.A., Newmeyer D.D., Wang H.G., Reed J.C., Nicholson D.W., Alnemri E.S., Green D.R., Martin S.J. Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J. Cell Biol. 1999, 144:281-292.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 281-292
-
-
Slee, E.A.1
Harte, M.T.2
Kluck, R.M.3
Wolf, B.B.4
Casiano, C.A.5
Newmeyer, D.D.6
Wang, H.G.7
Reed, J.C.8
Nicholson, D.W.9
Alnemri, E.S.10
Green, D.R.11
Martin, S.J.12
-
39
-
-
0035793580
-
Lysosomal protease pathways to apoptosis. Cleavage of bid, not pre-caspases, most likely route
-
Stoka V., Turk B., Schendel S.L., Kim T.H., Cirman T., Snipas S.J., Ellerby L.M., Bredensen D., Abrahamson M., Bromme D., Krajewski S., Reed J.C., Yin X.M., Turk V., Salvesen G.S. Lysosomal protease pathways to apoptosis. Cleavage of bid, not pre-caspases, most likely route. J. Biol. Chem. 2001, 276:3149-3157.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3149-3157
-
-
Stoka, V.1
Turk, B.2
Schendel, S.L.3
Kim, T.H.4
Cirman, T.5
Snipas, S.J.6
Ellerby, L.M.7
Bredensen, D.8
Abrahamson, M.9
Bromme, D.10
Krajewski, S.11
Reed, J.C.12
Yin, X.M.13
Turk, V.14
Salvesen, G.S.15
-
40
-
-
0034652232
-
Caspase-2 mediates neuronal cell death induced by β-amyloid
-
Troy C.M., Rabacchi S.A., Friedman W.J., Frappier T.F., Brown K., Shelanski M.L. Caspase-2 mediates neuronal cell death induced by β-amyloid. J. Neurosci. 2000, 20:1386-1392.
-
(2000)
J. Neurosci.
, vol.20
, pp. 1386-1392
-
-
Troy, C.M.1
Rabacchi, S.A.2
Friedman, W.J.3
Frappier, T.F.4
Brown, K.5
Shelanski, M.L.6
-
41
-
-
0033566644
-
Activation of neuronal caspase-3 by intracellular accumulation of wild-type Alzheimer amyloid precursor protein
-
Uetsuki T., Takemoto K., Nishimura I., Okamoto M., Niinobe M., Momoi T., Miura M., Yoshikawa K. Activation of neuronal caspase-3 by intracellular accumulation of wild-type Alzheimer amyloid precursor protein. J. Neurosci. 1999, 19:6955-6964.
-
(1999)
J. Neurosci.
, vol.19
, pp. 6955-6964
-
-
Uetsuki, T.1
Takemoto, K.2
Nishimura, I.3
Okamoto, M.4
Niinobe, M.5
Momoi, T.6
Miura, M.7
Yoshikawa, K.8
-
42
-
-
34547107293
-
Virtual screening for finding natural inhibitor against cathepsin-L for SARS therapy
-
Wang S.Q., Du Q.S., Zhao K., Li A.X., Wei D.Q., Chou K.C. Virtual screening for finding natural inhibitor against cathepsin-L for SARS therapy. Amino Acids 2007, 33:129-135.
-
(2007)
Amino Acids
, vol.33
, pp. 129-135
-
-
Wang, S.Q.1
Du, Q.S.2
Zhao, K.3
Li, A.X.4
Wei, D.Q.5
Chou, K.C.6
-
43
-
-
0035029801
-
Sublethal concentration of prion peptide PrP106-126 or the amyloid peptide protein of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons
-
White A.R., Guirguis R., Brazier M.W., Jobling M.F., Hill A.F., Beyreuther K., Barrow C.J., Master C.L., Collins S.J., Cappai R. Sublethal concentration of prion peptide PrP106-126 or the amyloid peptide protein of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons. Neurobiol. Dis. 2001, 8:299-316.
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 299-316
-
-
White, A.R.1
Guirguis, R.2
Brazier, M.W.3
Jobling, M.F.4
Hill, A.F.5
Beyreuther, K.6
Barrow, C.J.7
Master, C.L.8
Collins, S.J.9
Cappai, R.10
-
44
-
-
0242539781
-
Sustained capain activation associated with lysosomal rupture executes necrosis of the postischemic CAI neurons in primates
-
Yamashima T., Tonchev A.B., Tsukada T., Saido T.C., Imajoh-Ohmi S., Momoi T., Kominami E. Sustained capain activation associated with lysosomal rupture executes necrosis of the postischemic CAI neurons in primates. Hippocampus 2003, 13(7):791-800.
-
(2003)
Hippocampus
, vol.13
, Issue.7
, pp. 791-800
-
-
Yamashima, T.1
Tonchev, A.B.2
Tsukada, T.3
Saido, T.C.4
Imajoh-Ohmi, S.5
Momoi, T.6
Kominami, E.7
-
45
-
-
3843076296
-
Bax-inhibiting peptide derived from mouse and rat Ku70
-
Yoshida T., Tomioka I., Nagahara T., Holyst T., Sawada M., Hayes P., Gama V., Okuno M., Chen Y., Abe Y., Kanouchi T., Sasada H., Wang D., Yokota T., Sato E., Matsuyama S. Bax-inhibiting peptide derived from mouse and rat Ku70. Biochem. Biophys. Res. Commun. 2004, 321:961-966.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.321
, pp. 961-966
-
-
Yoshida, T.1
Tomioka, I.2
Nagahara, T.3
Holyst, T.4
Sawada, M.5
Hayes, P.6
Gama, V.7
Okuno, M.8
Chen, Y.9
Abe, Y.10
Kanouchi, T.11
Sasada, H.12
Wang, D.13
Yokota, T.14
Sato, E.15
Matsuyama, S.16
-
46
-
-
0037197938
-
Lysosomal destabilization in p53-induced apoptosis
-
Yuan X.-M., Li W., Dalen H., Lotem J., Kama R., Sachs L., Brunk U.T. Lysosomal destabilization in p53-induced apoptosis. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:6286-6291.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 6286-6291
-
-
Yuan, X.-M.1
Li, W.2
Dalen, H.3
Lotem, J.4
Kama, R.5
Sachs, L.6
Brunk, U.T.7
-
48
-
-
0035861890
-
Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis
-
Zhao M., Eaton J.W., Brunk U.T. Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis. FEBS Lett. 2001, 14:405-412.
-
(2001)
FEBS Lett.
, vol.14
, pp. 405-412
-
-
Zhao, M.1
Eaton, J.W.2
Brunk, U.T.3
|