Up-regulation of the lysosomal system in experimental models of neuronal injury: Implications for Alzheimer's disease

Neuroscience

Volumn 100, Issue 3, 2000, Pages 663-675

  Adamec, E ^a   Mohan, P S ^b,c   Cataldo, A M ^a,b,c   Vonsattel, J P ^a,d   Nixon, R A ^b,c  

^a MCLEAN HOSPITAL   (United States)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Apoptosis; Caspase 3; Cathepsin D; Necrosis; Neurodegeneration; Oncosis

Indexed keywords

6,7 DINITRO 2,3 QUINOXALINEDIONE; CAMPTOTHECIN; CASPASE 3; CATHEPSIN D; DIZOCILPINE MALEATE; MENADIONE; STAUROSPORINE;

ALZHEIMER DISEASE; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; HIPPOCAMPUS; IMMUNOBLOTTING; LYSOSOME; NERVE CELL NECROSIS; NERVE DEGENERATION; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ASTROCYTES; BLOTTING, WESTERN; CATHEPSIN D; FEMALE; HIPPOCAMPUS; HUMAN; LYSOSOMES; MALE; MIDDLE AGE; NEURONS; PEPSTATINS; SUPPORT, U.S. GOV'T, P.H.S.; UP-REGULATION; WOUNDS AND INJURIES;

EID: 0034721509     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00281-5     Document Type: Article

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