-
1
-
-
33644814459
-
Thrombolysis in acute ischemic stroke: Successes, failures, and new hopes
-
Davalos, A. Thrombolysis in acute ischemic stroke: successes, failures, and new hopes. Cerebrovasc. Dis., 2005, 20 Suppl 2, 135-139.
-
(2005)
Cerebrovasc. Dis.
, vol.20
, Issue.SUPPL. 2
, pp. 135-139
-
-
Davalos, A.1
-
2
-
-
0033600277
-
The changing landscape of ischaemic brain injury mechanisms
-
Lee, J.M.; Zipfel, G.J.; Choi, D.W. The changing landscape of ischaemic brain injury mechanisms. Nature, 1999, 399, A7-14.
-
(1999)
Nature
, vol.399
-
-
Lee, J.M.1
Zipfel, G.J.2
Choi, D.W.3
-
3
-
-
0029888311
-
Role of oxidants in ischemic brain damage
-
Chan, P.H. Role of oxidants in ischemic brain damage. Stroke, 1996, 27, 1124-1129.
-
(1996)
Stroke
, vol.27
, pp. 1124-1129
-
-
Chan, P.H.1
-
4
-
-
0031953601
-
Calcium in ischemic cell death
-
Kristian, T.; Siesjo, B.K. Calcium in ischemic cell death. Stroke, 1998, 29, 705-718.
-
(1998)
Stroke
, vol.29
, pp. 705-718
-
-
Kristian, T.1
Siesjo, B.K.2
-
5
-
-
35848932091
-
Mechanisms of impaired mitochondrial energy metabolism in acute and chronic neurodegenerative disorders
-
Soane, L.; Kahraman, S.; Kristian, T.; Fiskum, G. Mechanisms of impaired mitochondrial energy metabolism in acute and chronic neurodegenerative disorders. J. Neurosci. Res., 2007, 85, 3407-15.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 3407-3415
-
-
Soane, L.1
Kahraman, S.2
Kristian, T.3
Fiskum, G.4
-
6
-
-
75649106812
-
Inflammation in Ischemic Brain Injury: Current Advances and Future Perspectives
-
Xia, W.; Han, J.; Huang, G.; Ying, W. Inflammation in Ischemic Brain Injury: Current Advances and Future Perspectives. Clin. Exp. Pharmacol. Physiol., 2010, 37, 253-8.
-
(2010)
Clin. Exp. Pharmacol. Physiol.
, vol.37
, pp. 253-258
-
-
Xia, W.1
Han, J.2
Huang, G.3
Ying, W.4
-
7
-
-
0035149749
-
Reactive oxygen radicals in signaling and damage in the ischemic brain
-
Chan, P.H. Reactive oxygen radicals in signaling and damage in the ischemic brain. J. Cereb. Blood Flow Metab., 2001, 21, 2-14.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 2-14
-
-
Chan, P.H.1
-
8
-
-
0031081488
-
Deleterious network hypothesis of aging
-
Ying, W. Deleterious network hypothesis of aging. Med. Hypotheses, 1997, 48, 143-148.
-
(1997)
Med. Hypotheses
, vol.48
, pp. 143-148
-
-
Ying, W.1
-
9
-
-
0036152892
-
Iron and Parkinson's disease
-
Wolozin, B.; Golts, N. Iron and Parkinson's disease. Neuroscientist, 2002, 8, 22-32.
-
(2002)
Neuroscientist
, vol.8
, pp. 22-32
-
-
Wolozin, B.1
Golts, N.2
-
10
-
-
10244246626
-
Mitochondrial dysfunction and oxidative damage in Alzheimer's and Parkinson's diseases and coenzyme Q10 as a potential treatment
-
Beal, M.F. Mitochondrial dysfunction and oxidative damage in Alzheimer's and Parkinson's diseases and coenzyme Q10 as a potential treatment. J. Bioenerg. Biomembr., 2004, 36, 381-386.
-
(2004)
J. Bioenerg. Biomembr.
, vol.36
, pp. 381-386
-
-
Beal, M.F.1
-
11
-
-
0029806859
-
A new hypothesis of neurodegenerative diseases: The deleterious network hypothesis
-
Ying, W. A new hypothesis of neurodegenerative diseases: the deleterious network hypothesis. Med. Hypotheses, 1996, 47, 307-313.
-
(1996)
Med. Hypotheses
, vol.47
, pp. 307-313
-
-
Ying, W.1
-
12
-
-
24644443839
-
Oxidative stress: The old enemy in Alzheimer's disease pathophysiology
-
Moreira, P.I.; Honda, K.; Liu, Q.; Santos, M.S.; Oliveira, C.R.; Aliev, G.; Nunomura, A.; Zhu, X.; Smith, M.A.; Perry, G. Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Curr. Alzheimer Res., 2005, 2, 403-408.
-
(2005)
Curr. Alzheimer Res.
, vol.2
, pp. 403-408
-
-
Moreira, P.I.1
Honda, K.2
Liu, Q.3
Santos, M.S.4
Oliveira, C.R.5
Aliev, G.6
Nunomura, A.7
Zhu, X.8
Smith, M.A.9
Perry, G.10
-
13
-
-
1842453324
-
Oxidative stress signaling in Alzheimer's disease
-
Zhu, X.; Raina, A.K.; Lee, H.G.; Casadesus, G.; Smith, M.A.; Perry, G. Oxidative stress signaling in Alzheimer's disease. Brain Res., 2004, 1000, 32-39.
-
(2004)
Brain Res.
, vol.1000
, pp. 32-39
-
-
Zhu, X.1
Raina, A.K.2
Lee, H.G.3
Casadesus, G.4
Smith, M.A.5
Perry, G.6
-
14
-
-
2342417953
-
Oxidative stress and neuroinflammation in Alzheimer's disease and amyotrophic lateral sclerosis: Common links and potential therapeutic targets
-
Mhatre, M.; Floyd, R.A.; Hensley, K. Oxidative stress and neuroinflammation in Alzheimer's disease and amyotrophic lateral sclerosis: common links and potential therapeutic targets. J. Alzheimers Dis., 2004, 6, 147-157.
-
(2004)
J. Alzheimers Dis.
, vol.6
, pp. 147-157
-
-
Mhatre, M.1
Floyd, R.A.2
Hensley, K.3
-
15
-
-
0345055313
-
Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production
-
Keller, J.N.; Guo, Q.; Holtsberg, F.W.; Bruce-Keller, A.J.; Mattson, M.P. Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production. J. Neurosci., 1998, 18, 4439-4450.
-
(1998)
J. Neurosci.
, vol.18
, pp. 4439-4450
-
-
Keller, J.N.1
Guo, Q.2
Holtsberg, F.W.3
Bruce-Keller, A.J.4
Mattson, M.P.5
-
16
-
-
34247195332
-
+ and NADH in brain functions, brain diseases and brain aging
-
+ and NADH in brain functions, brain diseases and brain aging. Front. Biosci., 2007, 12, 1863-1888.
-
(2007)
Front. Biosci.
, vol.12
, pp. 1863-1888
-
-
Ying, W.1
-
17
-
-
0036733355
-
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
-
Virag, L.; Szabo, C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol. Rev., 2002, 54, 375-429.
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 375-429
-
-
Virag, L.1
Szabo, C.2
-
18
-
-
0030842946
-
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia
-
Eliasson, M.J.; Sampei, K.; Mandir, A.S.; Hurn, P.D.; Traystman, R.J.; Bao, J.; Pieper, A.; Wang, Z.Q.; Dawson, T.M.; Snyder, S.H.; Dawson, V.L. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat. Med., 1997, 3, 1089-1095.
-
(1997)
Nat. Med.
, vol.3
, pp. 1089-1095
-
-
Eliasson, M.J.1
Sampei, K.2
Mandir, A.S.3
Hurn, P.D.4
Traystman, R.J.5
Bao, J.6
Pieper, A.7
Wang, Z.Q.8
Dawson, T.M.9
Snyder, S.H.10
Dawson, V.L.11
-
19
-
-
0030832874
-
Ischemic brain injury is mediated by the activation of poly(ADP- ribose)polymerase
-
Endres, M.; Wang, Z.Q.; Namura, S.; Waeber, C.; Moskowitz, M.A. Ischemic brain injury is mediated by the activation of poly(ADP- ribose)polymerase. J. Cereb. Blood Flow Metab., 1997, 17, 1143-1151.
-
(1997)
J. Cereb. Blood Flow Metab.
, vol.17
, pp. 1143-1151
-
-
Endres, M.1
Wang, Z.Q.2
Namura, S.3
Waeber, C.4
Moskowitz, M.A.5
-
20
-
-
0041573041
-
NAD repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes
-
Ying, W.; Garnier, P.; Swanson, R.A. NAD repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes. Biochem. Biophys. Res. Commun., 2003, 308, 809-813.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.308
, pp. 809-813
-
-
Ying, W.1
Garnier, P.2
Swanson, R.A.3
-
21
-
-
2442624618
-
+ depletion and mitochondrial permeability transition
-
+ depletion and mitochondrial permeability transition. J.Biol.Chem., 2004, 279, 18895-18902.
-
(2004)
J.Biol.Chem.
, vol.279
, pp. 18895-18902
-
-
Alano, C.C.1
Ying, W.2
Swanson, R.A.3
-
22
-
-
52449091282
-
Cellular NAD replenishment confers marked neuroprotection against ischemic cell death: Role of enhanced DNA repair
-
Wang, S.; Xing, Z.; Vosler, P.S.; Yin, H.; Li, W.; Zhang, F.; Signore, A.P.; Stetler, R.A.; Gao, Y.; Chen, J. Cellular NAD replenishment confers marked neuroprotection against ischemic cell death: role of enhanced DNA repair. Stroke, 2008, 39, 2587-2595.
-
(2008)
Stroke
, vol.39
, pp. 2587-2595
-
-
Wang, S.1
Xing, Z.2
Vosler, P.S.3
Yin, H.4
Li, W.5
Zhang, F.6
Signore, A.P.7
Stetler, R.A.8
Gao, Y.9
Chen, J.10
-
23
-
-
34248375793
-
+ profoundly decreases brain injury in a rat model of transient focal ischemia
-
+ profoundly decreases brain injury in a rat model of transient focal ischemia. Front. Biosci., 2007, 12, 2728-2734.
-
(2007)
Front. Biosci.
, vol.12
, pp. 2728-2734
-
-
Ying, W.1
Wei, G.2
Wang, D.3
Wang, Q.4
Tang, X.5
Shi, J.6
Zhang, P.7
Lu, H.8
-
24
-
-
0020397137
-
The effect of hyperoxia on superoxide production by lung submitochondrial particles
-
Turrens, J.F.; Freeman, B.A.; Levitt, J.G.; Crapo, J.D. The effect of hyperoxia on superoxide production by lung submitochondrial particles. Arch. Biochem. Biophys., 1982, 217, 401-410.
-
(1982)
Arch. Biochem. Biophys.
, vol.217
, pp. 401-410
-
-
Turrens, J.F.1
Freeman, B.A.2
Levitt, J.G.3
Crapo, J.D.4
-
25
-
-
0027218413
-
Increased NADPHand NADH-dependent production of superoxide and hydroxyl radical by microsomes after chronic ethanol treatment
-
Rashba-Step, J.; Turro, N.J.; Cederbaum, A.I. Increased NADPHand NADH-dependent production of superoxide and hydroxyl radical by microsomes after chronic ethanol treatment. Arch. Biochem. Biophys., 1993, 300, 401-408.
-
(1993)
Arch. Biochem. Biophys.
, vol.300
, pp. 401-408
-
-
Rashba-Step, J.1
Turro, N.J.2
Cederbaum, A.I.3
-
26
-
-
0014962562
-
Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase
-
Fridovich, I. Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase. J. Biol. Chem., 1970, 245, 4053-4057.
-
(1970)
J. Biol. Chem.
, vol.245
, pp. 4053-4057
-
-
Fridovich, I.1
-
27
-
-
0000166417
-
Detection of superoxide generated by endothelial cells
-
Rosen, G.M.; Freeman, B.A. Detection of superoxide generated by endothelial cells. Proc. Natl. Acad. Sci. U.S.A., 1984, 81, 7269-7273.
-
(1984)
Proc. Natl. Acad. Sci. U.S.A.
, vol.81
, pp. 7269-7273
-
-
Rosen, G.M.1
Freeman, B.A.2
-
28
-
-
0016414528
-
Superoxide dismutases
-
Fridovich, I. Superoxide dismutases. Annu. Rev. Biochem., 1975, 44, 147-159.
-
(1975)
Annu. Rev. Biochem.
, vol.44
, pp. 147-159
-
-
Fridovich, I.1
-
29
-
-
0029091060
-
Biochemical changes associated with selective neuronal death following short-term cerebral ischaemia
-
Sims, N.R.; Zaidan, E. Biochemical changes associated with selective neuronal death following short-term cerebral ischaemia. Int. J. Biochem. Cell Biol., 1995, 27, 531-550.
-
(1995)
Int. J. Biochem. Cell Biol.
, vol.27
, pp. 531-550
-
-
Sims, N.R.1
Zaidan, E.2
-
30
-
-
0025854274
-
The double-edged role of nitric oxide in brain function and superoxide-mediated injury
-
Beckman, J.S. The double-edged role of nitric oxide in brain function and superoxide-mediated injury. J. Dev. Physiol., 1991, 15, 53-59.
-
(1991)
J. Dev. Physiol.
, vol.15
, pp. 53-59
-
-
Beckman, J.S.1
-
31
-
-
0028026868
-
Nitric oxide synthase: Aspects concerning structure and catalysis
-
Marletta, M.A. Nitric oxide synthase: aspects concerning structure and catalysis. Cell, 1994, 78, 927-930.
-
(1994)
Cell
, vol.78
, pp. 927-930
-
-
Marletta, M.A.1
-
32
-
-
0028902552
-
Nitric oxide synthases: Properties and catalytic mechanism
-
Griffith, O.W.; Stuehr, D.J. Nitric oxide synthases: properties and catalytic mechanism. Annu. Rev. Physiol., 1995, 57, 707-736.
-
(1995)
Annu. Rev. Physiol.
, vol.57
, pp. 707-736
-
-
Griffith, O.W.1
Stuehr, D.J.2
-
34
-
-
4544230902
-
Neuroprotection in ischemia: Blocking calciumpermeable acid-sensing ion channels
-
Xiong, Z.G.; Zhu, X.M.; Chu, X.P.; Minami, M.; Hey, J.; Wei, W.L.; MacDonald, J.F.; Wemmie, J.A.; Price, M.P.; Welsh, M.J.; Simon, R.P. Neuroprotection in ischemia: blocking calciumpermeable acid-sensing ion channels. Cell, 2004, 118, 687-698.
-
(2004)
Cell
, vol.118
, pp. 687-698
-
-
Xiong, Z.G.1
Zhu, X.M.2
Chu, X.P.3
Minami, M.4
Hey, J.5
Wei, W.L.6
MacDonald, J.F.7
Wemmie, J.A.8
Price, M.P.9
Welsh, M.J.10
Simon, R.P.11
-
35
-
-
0032880761
-
Acidosis potentiates oxidative neuronal death by multiple mechanisms
-
Ying, W.; Han, S.K.; Miller, J.W.; Swanson, R.A. Acidosis potentiates oxidative neuronal death by multiple mechanisms. J.Neurochem., 1999, 73, 1549-1556.
-
(1999)
J. Neurochem.
, vol.73
, pp. 1549-1556
-
-
Ying, W.1
Han, S.K.2
Miller, J.W.3
Swanson, R.A.4
-
36
-
-
0026497926
-
Excitotoxic cell death
-
Choi, D.W. Excitotoxic cell death. J.Neurobiol., 1992, 23, 1261-1276.
-
(1992)
J. Neurobiol.
, vol.23
, pp. 1261-1276
-
-
Choi, D.W.1
-
37
-
-
67649852282
-
Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion
-
Chen, H.; Song, Y.S.; Chan, P.H. Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. J. Cereb. Blood Flow Metab., 2009, 29, 1262-1272.
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, pp. 1262-1272
-
-
Chen, H.1
Song, Y.S.2
Chan, P.H.3
-
38
-
-
21444442708
-
Nitric oxide synthase inhibitors in experimental ischemic stroke and their effects on infarct size and cerebral blood flow: A systematic review
-
Willmot, M.; Gibson, C.; Gray, L.; Murphy, S.; Bath, P. Nitric oxide synthase inhibitors in experimental ischemic stroke and their effects on infarct size and cerebral blood flow: a systematic review. Free Radic. Biol. Med., 2005, 39, 412-425.
-
(2005)
Free Radic. Biol. Med.
, vol.39
, pp. 412-425
-
-
Willmot, M.1
Gibson, C.2
Gray, L.3
Murphy, S.4
Bath, P.5
-
39
-
-
31344432053
-
Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia
-
Muralikrishna Adibhatla, R.; Hatcher, J.F. Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia. Free Radic. Biol. Med., 2006, 40, 376-387.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 376-387
-
-
Muralikrishna Adibhatla, R.1
Hatcher, J.F.2
-
40
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
-
Bedard, K.; Krause, K.H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev., 2007, 87, 245-313.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
41
-
-
33749047437
-
Localizing NADPH oxidase-derived ROS
-
Ushio-Fukai, M. Localizing NADPH oxidase-derived ROS. Sci. STKE, 2006, 2006, re8.
-
(2006)
Sci. STKE
, vol.2006
-
-
Ushio-Fukai, M.1
-
42
-
-
0036436238
-
The role of NADPH oxidase and neuronal nitric oxide synthase in zinc- induced poly(ADP-ribose) polymerase activation and cell death in cortical culture
-
Kim, Y.H.; Koh, J.Y. The role of NADPH oxidase and neuronal nitric oxide synthase in zinc- induced poly(ADP-ribose) polymerase activation and cell death in cortical culture. Exp. Neurol., 2002, 177, 407-418.
-
(2002)
Exp. Neurol.
, vol.177
, pp. 407-418
-
-
Kim, Y.H.1
Koh, J.Y.2
-
43
-
-
1642499152
-
Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase
-
Abramov, A.Y.; Canevari, L.; Duchen, M.R. Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. J. Neurosci., 2004, 24, 565-575.
-
(2004)
J. Neurosci.
, vol.24
, pp. 565-575
-
-
Abramov, A.Y.1
Canevari, L.2
Duchen, M.R.3
-
44
-
-
33846818524
-
Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation
-
Abramov, A.Y.; Scorziello, A.; Duchen, M.R. Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation. J. Neurosci., 2007, 27, 1129-1138.
-
(2007)
J. Neurosci.
, vol.27
, pp. 1129-1138
-
-
Abramov, A.Y.1
Scorziello, A.2
Duchen, M.R.3
-
45
-
-
67649800742
-
NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation
-
Brennan, A.M.; Suh, S.W.; Won, S.J.; Narasimhan, P.; Kauppinen, T.M.; Lee, H.; Edling, Y.; Chan, P.H.; Swanson, R.A. NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation. Nat. Neurosci., 2009, 12, 857-863.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 857-863
-
-
Brennan, A.M.1
Suh, S.W.2
Won, S.J.3
Narasimhan, P.4
Kauppinen, T.M.5
Lee, H.6
Edling, Y.7
Chan, P.H.8
Swanson, R.A.9
-
46
-
-
34547858520
-
Apocynin attenuates cerebral infarction after transient focal ischaemia in rats
-
Tang, L.L.; Ye, K.; Yang, X.F.; Zheng, J.S. Apocynin attenuates cerebral infarction after transient focal ischaemia in rats. J. Int. Med. Res., 2007, 35, 517-522.
-
(2007)
J. Int. Med. Res.
, vol.35
, pp. 517-522
-
-
Tang, L.L.1
Ye, K.2
Yang, X.F.3
Zheng, J.S.4
-
47
-
-
35649015344
-
NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke
-
Kahles, T.; Luedike, P.; Endres, M.; Galla, H.J.; Steinmetz, H.; Busse, R.; Neumann-Haefelin, T.; Brandes, R.P. NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke. Stroke, 2007, 38, 3000-3006.
-
(2007)
Stroke
, vol.38
, pp. 3000-3006
-
-
Kahles, T.1
Luedike, P.2
Endres, M.3
Galla, H.J.4
Steinmetz, H.5
Busse, R.6
Neumann-Haefelin, T.7
Brandes, R.P.8
-
48
-
-
72449142133
-
CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia
-
Kim, G.S.; Jung, J.E.; Niizuma, K.; Chan, P.H. CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia. J. Neurosci., 2009, 29, 14779-14789.
-
(2009)
J. Neurosci.
, vol.29
, pp. 14779-14789
-
-
Kim, G.S.1
Jung, J.E.2
Niizuma, K.3
Chan, P.H.4
-
49
-
-
70449397081
-
Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation
-
Zhang, Q.G.; Raz, L.; Wang, R.; Han, D.; De Sevilla, L.; Yang, F.; Vadlamudi, R.K.; Brann, D.W. Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation. J. Neurosci., 2009, 29, 13823-13836.
-
(2009)
J. Neurosci.
, vol.29
, pp. 13823-13836
-
-
Zhang, Q.G.1
Raz, L.2
Wang, R.3
Han, D.4
de Sevilla, L.5
Yang, F.6
Vadlamudi, R.K.7
Brann, D.W.8
-
50
-
-
21444439103
-
NAD(P)H oxidase activation: A potential target mechanism for diabetic vascular complications, progressive beta-cell dysfunction and metabolic syndrome
-
Inoguchi, T.; Nawata, H. NAD(P)H oxidase activation: a potential target mechanism for diabetic vascular complications, progressive beta-cell dysfunction and metabolic syndrome. Curr. Drug Targets, 2005, 6, 495-501.
-
(2005)
Curr. Drug Targets
, vol.6
, pp. 495-501
-
-
Inoguchi, T.1
Nawata, H.2
-
51
-
-
0028294246
-
Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
-
Zhang, J.; Dawson, V.L.; Dawson, T.M.; Snyder, S.H. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science, 1994, 263, 687-689.
-
(1994)
Science
, vol.263
, pp. 687-689
-
-
Zhang, J.1
Dawson, V.L.2
Dawson, T.M.3
Snyder, S.H.4
-
52
-
-
0031723465
-
Enhanced poly(ADP-ribosyl)ation after focal ischemia in rat brain
-
Tokime, T.; Nozaki, K.; Sugino, T.; Kikuchi, H.; Hashimoto, N.; Ueda, K. Enhanced poly(ADP-ribosyl)ation after focal ischemia in rat brain. J. Cereb. Blood Flow Metab., 1998, 18, 991-997.
-
(1998)
J. Cereb. Blood Flow Metab.
, vol.18
, pp. 991-997
-
-
Tokime, T.1
Nozaki, K.2
Sugino, T.3
Kikuchi, H.4
Hashimoto, N.5
Ueda, K.6
-
53
-
-
0032924142
-
Neuronal accumulation of poly(ADP-ribose) after brain ischaemia
-
Love, S.; Barber, R.; Wilcock, G.K. Neuronal accumulation of poly(ADP-ribose) after brain ischaemia. Neuropathol. Appl. Neurobiol., 1999, 25, 98-103.
-
(1999)
Neuropathol. Appl. Neurobiol.
, vol.25
, pp. 98-103
-
-
Love, S.1
Barber, R.2
Wilcock, G.K.3
-
54
-
-
63949084979
-
Inhibition of poly(ADP-ribose) polymerase suppresses inflammation and promotes recovery after ischemic injury
-
Kauppinen, T.M.; Suh, S.W.; Berman, A.E.; Hamby, A.M.; Swanson, R.A. Inhibition of poly(ADP-ribose) polymerase suppresses inflammation and promotes recovery after ischemic injury. J. Cereb. Blood Flow Metab., 2009, 29, 820-829.
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, pp. 820-829
-
-
Kauppinen, T.M.1
Suh, S.W.2
Berman, A.E.3
Hamby, A.M.4
Swanson, R.A.5
-
55
-
-
33847644971
-
The inflammatory response in stroke
-
Wang, Q.; Tang, X.N.; Yenari, M.A. The inflammatory response in stroke. J. Neuroimmunol., 2007, 184, 53-68.
-
(2007)
J. Neuroimmunol.
, vol.184
, pp. 53-68
-
-
Wang, Q.1
Tang, X.N.2
Yenari, M.A.3
-
56
-
-
0033198919
-
Poly(ADPribosyl) ation reactions in the regulation of nuclear functions
-
D'Amours, D.; Desnoyers, S.; D'Silva, I.; Poirier, G.G. Poly(ADPribosyl) ation reactions in the regulation of nuclear functions. Biochem. J., 1999, 342 (Pt 2), 249-268.
-
(1999)
Biochem. J.
, vol.342
, Issue.PART 2
, pp. 249-268
-
-
D'amours, D.1
Desnoyers, S.2
D'silva, I.3
Poirier, G.G.4
-
57
-
-
0035149749
-
Reactive oxygen radicals in signaling and damage in the ischemic brain
-
Chan, P.H. Reactive oxygen radicals in signaling and damage in the ischemic brain. J. Cereb. Blood Flow Metab., 2001, 21, 2-14.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 2-14
-
-
Chan, P.H.1
-
58
-
-
0034710285
-
A fast signal-induced activation of Poly(ADP-ribose) polymerase: A novel downstream target of phospholipase c
-
Homburg, S.; Visochek, L.; Moran, N.; Dantzer, F.; Priel, E.; Asculai, E.; Schwartz, D.; Rotter, V.; Dekel, N.; Cohen-Armon, M. A fast signal-induced activation of Poly(ADP-ribose) polymerase: a novel downstream target of phospholipase c. J. Cell Biol., 2000, 150, 293-307.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 293-307
-
-
Homburg, S.1
Visochek, L.2
Moran, N.3
Dantzer, F.4
Priel, E.5
Asculai, E.6
Schwartz, D.7
Rotter, V.8
Dekel, N.9
Cohen-Armon, M.10
-
59
-
-
0034233751
-
Effects of transient global ischemia and kainate on poly(ADP-ribose) polymerase (PARP) gene expression and proteolytic cleavage in gerbil and rat brains
-
Liu, J.; Ying, W.; Massa, S.; Duriez, P.J.; Swanson, R.A.; Poirier, G.G.; Sharp, F.R. Effects of transient global ischemia and kainate on poly(ADP-ribose) polymerase (PARP) gene expression and proteolytic cleavage in gerbil and rat brains. Brain Res. Mol. Brain Res., 2000, 80, 7-16.
-
(2000)
Brain Res. Mol. Brain Res.
, vol.80
, pp. 7-16
-
-
Liu, J.1
Ying, W.2
Massa, S.3
Duriez, P.J.4
Swanson, R.A.5
Poirier, G.G.6
Sharp, F.R.7
-
60
-
-
0038582584
-
Role of superoxide in poly(ADP-ribose) polymerase upregulation after transient cerebral ischemia
-
Narasimhan, P.; Fujimura, M.; Noshita, N.; Chan, P.H. Role of superoxide in poly(ADP-ribose) polymerase upregulation after transient cerebral ischemia. Brain Res. Mol. Brain Res., 2003, 113, 28-36.
-
(2003)
Brain Res. Mol. Brain Res.
, vol.113
, pp. 28-36
-
-
Narasimhan, P.1
Fujimura, M.2
Noshita, N.3
Chan, P.H.4
-
61
-
-
4444383142
-
PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury
-
Hagberg, H.; Wilson, M.A.; Matsushita, H.; Zhu, C.; Lange, M.; Gustavsson, M.; Poitras, M.F.; Dawson, T.M.; Dawson, V.L.; Northington, F.; Johnston, M.V. PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury. J. Neurochem., 2004, 90, 1068-1075.
-
(2004)
J. Neurochem.
, vol.90
, pp. 1068-1075
-
-
Hagberg, H.1
Wilson, M.A.2
Matsushita, H.3
Zhu, C.4
Lange, M.5
Gustavsson, M.6
Poitras, M.F.7
Dawson, T.M.8
Dawson, V.L.9
Northington, F.10
Johnston, M.V.11
-
62
-
-
17044430692
-
Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: Male toxicity, female protection
-
McCullough, L.D.; Zeng, Z.; Blizzard, K.K.; Debchoudhury, I.; Hurn, P.D. Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection. J. Cereb. Blood Flow Metab., 2005, 25, 502-512.
-
(2005)
J. Cereb. Blood Flow Metab.
, vol.25
, pp. 502-512
-
-
McCullough, L.D.1
Zeng, Z.2
Blizzard, K.K.3
Debchoudhury, I.4
Hurn, P.D.5
-
63
-
-
64249104435
-
Sex differences in the response to activation of the poly (ADPribose) polymerase pathway after experimental stroke
-
Yuan, M.; Siegel, C.; Zeng, Z.; Li, J.; Liu, F.; McCullough, L.D. Sex differences in the response to activation of the poly (ADPribose) polymerase pathway after experimental stroke. Exp. Neurol., 2009, 217, 210-218.
-
(2009)
Exp. Neurol.
, vol.217
, pp. 210-218
-
-
Yuan, M.1
Siegel, C.2
Zeng, Z.3
Li, J.4
Liu, F.5
McCullough, L.D.6
-
64
-
-
77951925836
-
Poly (ADP-ribose) polymerase-1 initiated neuronal cell death pathway--do androgens matter?
-
Vagnerova, K.; Liu, K.; Ardeshiri, A.; Cheng, J.; Murphy, S.J.; Hurn, P.D.; Herson, P.S. Poly (ADP-ribose) polymerase-1 initiated neuronal cell death pathway--do androgens matter? Neuroscience, 166, 476-481.
-
Neuroscience
, vol.166
, pp. 476-481
-
-
Vagnerova, K.1
Liu, K.2
Ardeshiri, A.3
Cheng, J.4
Murphy, S.J.5
Hurn, P.D.6
Herson, P.S.7
-
65
-
-
27144555760
-
Gender differences in the endotoxin- induced inflammatory and vascular responses: Potential role of poly(ADP-ribose) polymerase activation
-
Mabley, J.G.; Horvath, E.M.; Murthy, K.G.; Zsengeller, Z.; Vaslin, A.; Benko, R.; Kollai, M.; Szabo, C. Gender differences in the endotoxin- induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation. J. Pharmacol. Exp. Ther., 2005, 315, 812-820.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.315
, pp. 812-820
-
-
Mabley, J.G.1
Horvath, E.M.2
Murthy, K.G.3
Zsengeller, Z.4
Vaslin, A.5
Benko, R.6
Kollai, M.7
Szabo, C.8
-
66
-
-
0034068520
-
Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia
-
Nagayama, T.; Simon, R.P.; Chen, D.; Henshall, D.C.; Pei, W.; Stetler, R.A.; Chen, J. Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia. J. Neurochem., 2000, 74, 1636-1645.
-
(2000)
J. Neurochem.
, vol.74
, pp. 1636-1645
-
-
Nagayama, T.1
Simon, R.P.2
Chen, D.3
Henshall, D.C.4
Pei, W.5
Stetler, R.A.6
Chen, J.7
-
67
-
-
77649133016
-
+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death
-
+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death. J. Neurosci., 30, 2967-2978.
-
J. Neurosci.
, vol.30
, pp. 2967-2978
-
-
Alano, C.C.1
Garnier, P.2
Ying, W.3
Higashi, Y.4
Kauppinen, T.M.5
Swanson, R.A.6
-
68
-
-
33646481320
-
Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2
-
Kauppinen, T.M.; Chan, W.Y.; Suh, S.W.; Wiggins, A.K.; Huang, E.J.; Swanson, R.A. Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2. Proc. Natl. Acad. Sci. U.S.A., 2006, 103, 7136-7141.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 7136-7141
-
-
Kauppinen, T.M.1
Chan, W.Y.2
Suh, S.W.3
Wiggins, A.K.4
Huang, E.J.5
Swanson, R.A.6
-
69
-
-
33846362869
-
DNAindependent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: A link to histone acetylation
-
Cohen-Armon, M.; Visochek, L.; Rozensal, D.; Kalal, A.; Geistrikh, I.; Klein, R.; Bendetz-Nezer, S.; Yao, Z.; Seger, R. DNAindependent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation. Mol. Cell, 2007, 25, 297-308.
-
(2007)
Mol. Cell.
, vol.25
, pp. 297-308
-
-
Cohen-Armon, M.1
Visochek, L.2
Rozensal, D.3
Kalal, A.4
Geistrikh, I.5
Klein, R.6
Bendetz-Nezer, S.7
Yao, Z.8
Seger, R.9
-
70
-
-
33646827842
-
Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation
-
Xu, Y.; Huang, S.; Liu, Z.G.; Han, J. Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. J. Biol. Chem., 2006, 281, 8788-8795.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 8788-8795
-
-
Xu, Y.1
Huang, S.2
Liu, Z.G.3
Han, J.4
-
71
-
-
34247383146
-
c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1 activation
-
Zhang, S.; Lin, Y.; Kim, Y.S.; Hande, M.P.; Liu, Z.G.; Shen, H.M. c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1 activation. Cell Death Differ., 2007, 14, 1001-10.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1001-10
-
-
Zhang, S.1
Lin, Y.2
Kim, Y.S.3
Hande, M.P.4
Liu, Z.G.5
Shen, H.M.6
-
72
-
-
33745145870
-
Players in the PARP-1 cell-death pathway: JNK1 joins the cast
-
Alano, C.C.; Swanson, R.A. Players in the PARP-1 cell-death pathway: JNK1 joins the cast. Trends Biochem. Sci., 2006, 31, 309-311.
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 309-311
-
-
Alano, C.C.1
Swanson, R.A.2
-
73
-
-
4644307600
-
TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase
-
Fonfria, E.; Marshall, I.C.; Benham, C.D.; Boyfield, I.; Brown, J.D.; Hill, K.; Hughes, J.P.; Skaper, S.D.; McNulty, S. TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase. Br. J. Pharmacol., 2004, 143, 186-192.
-
(2004)
Br. J. Pharmacol.
, vol.143
, pp. 186-192
-
-
Fonfria, E.1
Marshall, I.C.2
Benham, C.D.3
Boyfield, I.4
Brown, J.D.5
Hill, K.6
Hughes, J.P.7
Skaper, S.D.8
McNulty, S.9
-
74
-
-
33744462507
-
Activation of the transient receptor potential M2 channel and poly(ADP-ribose) polymerase is involved in oxidative stress-induced cardiomyocyte death
-
Yang, K.T.; Chang, W.L.; Yang, P.C.; Chien, C.L.; Lai, M.S.; Su, M.J.; Wu, M.L. Activation of the transient receptor potential M2 channel and poly(ADP-ribose) polymerase is involved in oxidative stress-induced cardiomyocyte death. Cell Death Differ., 2005, 13, 1815-26.
-
(2005)
Cell Death Differ.
, vol.13
, pp. 1815-1826
-
-
Yang, K.T.1
Chang, W.L.2
Yang, P.C.3
Chien, C.L.4
Lai, M.S.5
Su, M.J.6
Wu, M.L.7
-
75
-
-
27644507847
-
Amyloid beta-peptide(1-42) and hydrogen peroxide-induced toxicity are mediated by TRPM2 in rat primary striatal cultures
-
Fonfria, E.; Marshall, I.C.; Boyfield, I.; Skaper, S.D.; Hughes, J.P.; Owen, D.E.; Zhang, W.; Miller, B.A.; Benham, C.D.; McNulty, S. Amyloid beta-peptide(1-42) and hydrogen peroxide-induced toxicity are mediated by TRPM2 in rat primary striatal cultures. J. Neurochem., 2005, 95, 715-723.
-
(2005)
J. Neurochem.
, vol.95
, pp. 715-723
-
-
Fonfria, E.1
Marshall, I.C.2
Boyfield, I.3
Skaper, S.D.4
Hughes, J.P.5
Owen, D.E.6
Zhang, W.7
Miller, B.A.8
Benham, C.D.9
McNulty, S.10
-
76
-
-
33845301167
-
Poly(ADP-ribose) (PAR) polymer is a death signal
-
Andrabi, S.A.; Kim, N.S.; Yu, S.W.; Wang, H.; Koh, D.W.; Sasaki, M.; Klaus, J.A.; Otsuka, T.; Zhang, Z.; Koehler, R.C.; Hurn, P.D.; Poirier, G.G.; Dawson, V.L.; Dawson, T.M. Poly(ADP-ribose) (PAR) polymer is a death signal. Proc. Natl. Acad. Sci. U.S.A., 2006, 103, 18308-18313.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 18308-18313
-
-
Andrabi, S.A.1
Kim, N.S.2
Yu, S.W.3
Wang, H.4
Koh, D.W.5
Sasaki, M.6
Klaus, J.A.7
Otsuka, T.8
Zhang, Z.9
Koehler, R.C.10
Hurn, P.D.11
Poirier, G.G.12
Dawson, V.L.13
Dawson, T.M.14
-
77
-
-
33845317242
-
Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death
-
Yu, S.W.; Andrabi, S.A.; Wang, H.; Kim, N.S.; Poirier, G.G.; Dawson, T.M.; Dawson, V.L. Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death. Proc. Natl. Acad. Sci. U S A, 2006, 103, 18314-18319.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 18314-18319
-
-
Yu, S.W.1
Andrabi, S.A.2
Wang, H.3
Kim, N.S.4
Poirier, G.G.5
Dawson, T.M.6
Dawson, V.L.7
-
78
-
-
33750362174
-
Zinc neurotoxicity is dependent on intracellular NAD levels and the sirtuin pathway
-
Cai, A.L.; Zipfel, G.J.; Sheline, C.T. Zinc neurotoxicity is dependent on intracellular NAD levels and the sirtuin pathway. Eur. J. Neurosci., 2006, 24, 2169-2176.
-
(2006)
Eur. J. Neurosci.
, vol.24
, pp. 2169-2176
-
-
Cai, A.L.1
Zipfel, G.J.2
Sheline, C.T.3
-
79
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
Araki, T.; Sasaki, Y.; Milbrandt, J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science, 2004, 305, 1010-1013.
-
(2004)
Science
, vol.305
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
81
-
-
33744480316
-
+ and NADH in cellular functions and cell death
-
+ and NADH in cellular functions and cell death. Front. Biosci., 2006, 11, 3129-3148.
-
(2006)
Front. Biosci.
, vol.11
, pp. 3129-3148
-
-
Ying, W.1
-
82
-
-
37549068090
-
+/NADPH in cellular functions and cell death: Regulation and biological consequences
-
+/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxid. Redox Signal, 2008, 10, 179-206.
-
(2008)
Antioxid. Redox Signal
, vol.10
, pp. 179-206
-
-
Ying, W.1
-
83
-
-
34248375793
-
+ profoundly decreases brain injury in a rat model of transient focal ischemia
-
+ profoundly decreases brain injury in a rat model of transient focal ischemia. Front Biosci., 2007, 12, 2728-2734.
-
(2007)
Front Biosci
, vol.12
, pp. 2728-2734
-
-
Ying, W.1
Wei, G.2
Wang, D.3
Wang, Q.4
Tang, X.5
Shi, J.6
Zhang, P.7
Lu, H.8
-
84
-
-
84858620200
-
+ administration can profoundly decrease the brain injury induced by hypoxia-ischemia
-
In Press, Experimental Biology Conference Abstracts
-
+ administration can profoundly decrease the brain injury induced by hypoxia-ischemia. FASEB J., In Press, 2010 Experimental Biology Conference Abstracts.
-
(2010)
FASEB J.
-
-
He, X.1
Liu, N.2
Xia, W.3
Ying, W.4
-
85
-
-
70149095672
-
+ synthesis in cardiac myocytes
-
+ synthesis in cardiac myocytes. Circ. Res., 2009, 105, 481-491.
-
(2009)
Circ. Res.
, vol.105
, pp. 481-491
-
-
Hsu, C.P.1
Oka, S.2
Shao, D.3
Hariharan, N.4
Sadoshima, J.5
-
86
-
-
34249312281
-
+ for treating neurological diseases
-
+ for treating neurological diseases. Future Neurology, 2007, 2, 1-4.
-
(2007)
Future Neurology
, vol.2
, pp. 1-4
-
-
Ying, W.1
-
87
-
-
84858617150
-
+ induces C6 glioma cell death by generating oxidative stress and increasing intracellular calcium concentrations
-
In Press, Experimental Biology Conference Abstracts
-
+ induces C6 glioma cell death by generating oxidative stress and increasing intracellular calcium concentrations. FASEB J., In Press, 2010 Experimental Biology Conference Abstracts.
-
(2010)
FASEB J.
-
-
Zhao, C.1
Hong, Y.2
Han, J.3
Xia, W.4
Ying, W.5
-
88
-
-
0034193776
-
Sir2 links chromatin silencing, metabolism, and aging
-
Guarente, L. Sir2 links chromatin silencing, metabolism, and aging. Genes Dev., 2000, 14, 1021-1026.
-
(2000)
Genes Dev.
, vol.14
, pp. 1021-1026
-
-
Guarente, L.1
-
89
-
-
34547914840
-
Sirtuins: The 'magnificent seven', function, metabolism and longevity
-
Dali-Youcef, N.; Lagouge, M.; Froelich, S.; Koehl, C.; Schoonjans, K.; Auwerx, J. Sirtuins: the 'magnificent seven', function, metabolism and longevity. Ann. Med., 2007, 39, 335-345.
-
(2007)
Ann. Med.
, vol.39
, pp. 335-345
-
-
Dali-Youcef, N.1
Lagouge, M.2
Froelich, S.3
Koehl, C.4
Schoonjans, K.5
Auwerx, J.6
-
91
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung, F.; Hoberg, J.E.; Ramsey, C.S.; Keller, M.D.; Jones, D.R.; Frye, R.A.; Mayo, M.W. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J., 2004, 23, 2369-2380.
-
(2004)
EMBO J
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
92
-
-
28844474597
-
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling
-
Chen, J.; Zhou, Y.; Mueller-Steiner, S.; Chen, L.F.; Kwon, H.; Yi, S.; Mucke, L.; Gan, L. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. J. Biol. Chem., 2005, 280, 40364-40374.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40364-40374
-
-
Chen, J.1
Zhou, Y.2
Mueller-Steiner, S.3
Chen, L.F.4
Kwon, H.5
Yi, S.6
Mucke, L.7
Gan, L.8
-
93
-
-
33744475759
-
Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage
-
Kolthur-Seetharam, U.; Dantzer, F.; McBurney, M.W.; de Murcia, G.; Sassone-Corsi, P. Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage. Cell Cycle, 2006, 5, 873-7.
-
(2006)
Cell Cycle
, vol.5
, pp. 873-877
-
-
Kolthur-Seetharam, U.1
Dantzer, F.2
McBurney, M.W.3
de Murcia, G.4
Sassone-Corsi, P.5
-
94
-
-
38449084726
-
+ and NADH in ischemic brain injury
-
+ and NADH in ischemic brain injury. Front Biosci., 2008, 13, 1141-1151.
-
(2008)
Front Biosci.
, vol.13
, pp. 1141-1151
-
-
Ying, W.1
-
95
-
-
64749083797
-
Icariin enhances neuronal survival after oxygen and glucose deprivation by increasing SIRT1
-
Wang, L.; Zhang, L.; Chen, Z.B.; Wu, J.Y.; Zhang, X.; Xu, Y. Icariin enhances neuronal survival after oxygen and glucose deprivation by increasing SIRT1. Eur. J. Pharmacol., 2009, 609, 40-44.
-
(2009)
Eur. J. Pharmacol.
, vol.609
, pp. 40-44
-
-
Wang, L.1
Zhang, L.2
Chen, Z.B.3
Wu, J.Y.4
Zhang, X.5
Xu, Y.6
-
96
-
-
62249110887
-
Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1-uncoupling protein 2 pathway
-
Della-Morte, D.; Dave, K.R.; DeFazio, R.A.; Bao, Y.C.; Raval, A.P.; Perez-Pinzon, M.A. Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1-uncoupling protein 2 pathway. Neuroscience, 2009, 159, 993-1002.
-
(2009)
Neuroscience
, vol.159
, pp. 993-1002
-
-
Della-Morte, D.1
Dave, K.R.2
Defazio, R.A.3
Bao, Y.C.4
Raval, A.P.5
Perez-Pinzon, M.A.6
-
97
-
-
68549085061
-
Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection
-
Kakefuda, K.; Fujita, Y.; Oyagi, A.; Hyakkoku, K.; Kojima, T.; Umemura, K.; Tsuruma, K.; Shimazawa, M.; Ito, M.; Nozawa, Y.; Hara, H. Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection. Biochem. Biophys. Res. Commun., 2009, 387, 784-788.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.387
, pp. 784-788
-
-
Kakefuda, K.1
Fujita, Y.2
Oyagi, A.3
Hyakkoku, K.4
Kojima, T.5
Umemura, K.6
Tsuruma, K.7
Shimazawa, M.8
Ito, M.9
Nozawa, Y.10
Hara, H.11
-
98
-
-
57349153327
-
Beneficial effects of resveratrol on atherosclerosis
-
Fan, E.; Zhang, L.; Jiang, S.; Bai, Y. Beneficial effects of resveratrol on atherosclerosis. J. Med. Food, 2008, 11, 610-614.
-
(2008)
J. Med. Food.
, vol.11
, pp. 610-614
-
-
Fan, E.1
Zhang, L.2
Jiang, S.3
Bai, Y.4
-
99
-
-
0034660659
-
Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: Potential role of reactive oxygen intermediates and lipid peroxidation
-
Manna, S.K.; Mukhopadhyay, A.; Aggarwal, B.B. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation. J. Immunol., 2000, 164, 6509-6519.
-
(2000)
J. Immunol.
, vol.164
, pp. 6509-6519
-
-
Manna, S.K.1
Mukhopadhyay, A.2
Aggarwal, B.B.3
-
100
-
-
77949887506
-
Mammalian sirtuins: Biological insights and disease relevance
-
Haigis, M.C.; Sinclair, D.A. Mammalian sirtuins: biological insights and disease relevance. Annu. Rev. Pathol., 2010, 5, 253-295.
-
(2010)
Annu. Rev. Pathol.
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
101
-
-
77952547233
-
Ten years of NAD-dependent SIR2 family deacetylases: Implications for metabolic diseases
-
[Epub ahead of print]
-
Imai, S.I.; Guarente, L. Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases. Trends Pharmacol. Sci., 2010, [Epub ahead of print].
-
(2010)
Trends Pharmacol. Sci.
-
-
Imai, S.I.1
Guarente, L.2
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