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Volumn 85, Issue 15, 2007, Pages 3407-3415

Mechanisms of impaired mitochondrial energy metabolism in acute and chronic neurodegenerative disorders

Author keywords

Apoptosis; Calcium; Mitochondrial permeability transition; Nitric oxide; PARP 1

Indexed keywords

CYTOCHROME C; CYTOCHROME C OXIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; PYRIDINE NUCLEOTIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

EID: 35848932091     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21498     Document Type: Conference Paper
Times cited : (102)

References (104)
  • 2
    • 2442624618 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1- mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition
    • Alano CC, Ying W, Swanson RA. 2004. Poly(ADP-ribose) polymerase-1- mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition. J Biol Chem 279:18895-18902.
    • (2004) J Biol Chem , vol.279 , pp. 18895-18902
    • Alano, C.C.1    Ying, W.2    Swanson, R.A.3
  • 3
    • 33750608704 scopus 로고    scopus 로고
    • Glutamine: A Trojan horse in ammonia neurotoxicity
    • Albrecht J, Norenberg MD. 2006. Glutamine: a Trojan horse in ammonia neurotoxicity. Hepatology 44:788-794.
    • (2006) Hepatology , vol.44 , pp. 788-794
    • Albrecht, J.1    Norenberg, M.D.2
  • 4
    • 0028961896 scopus 로고
    • Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia
    • Allen KL, Almeida A, Bates TE, Clark JB. 1995. Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. J Neurochem 64:2222-2229.
    • (1995) J Neurochem , vol.64 , pp. 2222-2229
    • Allen, K.L.1    Almeida, A.2    Bates, T.E.3    Clark, J.B.4
  • 5
    • 0036329446 scopus 로고    scopus 로고
    • Cyclosporin A improves brain tissue oxygen consumption and learning/memory performance after lateral fluid percussion injury in rats
    • Alessandri B, Rice AC, Levasseur J, DeFord M, Hamm RJ, Bullock MR. 2002. Cyclosporin A improves brain tissue oxygen consumption and learning/memory performance after lateral fluid percussion injury in rats. J Neurotrauma 19:829-841.
    • (2002) J Neurotrauma , vol.19 , pp. 829-841
    • Alessandri, B.1    Rice, A.C.2    Levasseur, J.3    DeFord, M.4    Hamm, R.J.5    Bullock, M.R.6
  • 8
    • 21244446551 scopus 로고    scopus 로고
    • Properties of the permeability transition pore in mitochondria devoid of cyclophilin D
    • Basso E, Fante L, Fowlkes J, Petronilli V, Forte MA, Bernardi P. 2005. Properties of the permeability transition pore in mitochondria devoid of cyclophilin D. J Biol Chem 280:18558-18561.
    • (2005) J Biol Chem , vol.280 , pp. 18558-18561
    • Basso, E.1    Fante, L.2    Fowlkes, J.3    Petronilli, V.4    Forte, M.A.5    Bernardi, P.6
  • 9
    • 0021997074 scopus 로고
    • Poly(ADP-ribose) in the cellular response to DNA damage
    • Berger NA. 1985. Poly(ADP-ribose) in the cellular response to DNA damage. Radiat Res 101:4-15.
    • (1985) Radiat Res , vol.101 , pp. 4-15
    • Berger, N.A.1
  • 11
  • 12
    • 0026687312 scopus 로고
    • Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations
    • Bernardi P, Vassanelli S, Veronese P, Colonna R, Szabo I, Zoratti M. 1992. Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations. J Biol Chem 267:2934-2939.
    • (1992) J Biol Chem , vol.267 , pp. 2934-2939
    • Bernardi, P.1    Vassanelli, S.2    Veronese, P.3    Colonna, R.4    Szabo, I.5    Zoratti, M.6
  • 14
    • 33750362174 scopus 로고    scopus 로고
    • Zinc neurotoxicity is dependent on intracellular NAD levels and the sirtuin pathway
    • Cai AL, Zipfel GJ, Sheline CT. 2006. Zinc neurotoxicity is dependent on intracellular NAD levels and the sirtuin pathway. Eur J Neurosci 24:2169-2176.
    • (2006) Eur J Neurosci , vol.24 , pp. 2169-2176
    • Cai, A.L.1    Zipfel, G.J.2    Sheline, C.T.3
  • 15
    • 0022492499 scopus 로고
    • DNA strand breaks, NAD metabolism, and programmed cell death
    • Carson DA, Seto S, Wasson DB, Carrera CJ. 1986. DNA strand breaks, NAD metabolism, and programmed cell death. Exp Cell Res 164:273-281.
    • (1986) Exp Cell Res , vol.164 , pp. 273-281
    • Carson, D.A.1    Seto, S.2    Wasson, D.B.3    Carrera, C.J.4
  • 16
    • 33746933765 scopus 로고    scopus 로고
    • The many shapes of mitochondrial death
    • Cereghetti GM, Scorrano L. 2006. The many shapes of mitochondrial death. Oncogene 25:4717-4724.
    • (2006) Oncogene , vol.25 , pp. 4717-4724
    • Cereghetti, G.M.1    Scorrano, L.2
  • 18
    • 0026705070 scopus 로고
    • Effect of dichloroacetate on recovery of brain lactate, phosphorus energy metabolites, and glutamate during reperfusion after complete cerebral ischemia in rats
    • Chang LH, Shimizu H, Abiko H, Swanson RA, Faden AI, James TL, Weinstein PR. 1992. Effect of dichloroacetate on recovery of brain lactate, phosphorus energy metabolites, and glutamate during reperfusion after complete cerebral ischemia in rats. J Cereb Blood Flow Metab. 12:1030-1038.
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 1030-1038
    • Chang, L.H.1    Shimizu, H.2    Abiko, H.3    Swanson, R.A.4    Faden, A.I.5    James, T.L.6    Weinstein, P.R.7
  • 19
    • 0036479049 scopus 로고    scopus 로고
    • Mitochondrial intermembrane junctional complexes and their involvement in cell death
    • Crompton M, Barksby E, Johnson N, Capano M. 2002. Mitochondrial intermembrane junctional complexes and their involvement in cell death. Biochimie 84:143-152.
    • (2002) Biochimie , vol.84 , pp. 143-152
    • Crompton, M.1    Barksby, E.2    Johnson, N.3    Capano, M.4
  • 20
    • 33644859410 scopus 로고    scopus 로고
    • Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics
    • Delivani P, Adrain C, Taylor RC, Duriez PJ, Martin SJ. 2006. Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics. Mol Cell 21:761-773.
    • (2006) Mol Cell , vol.21 , pp. 761-773
    • Delivani, P.1    Adrain, C.2    Taylor, R.C.3    Duriez, P.J.4    Martin, S.J.5
  • 21
    • 0035951823 scopus 로고    scopus 로고
    • Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperrusion of the heart
    • Di Lisa F, Menabo R, Canton M, Barile M, Bernardi P. 2001. Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperrusion of the heart. J Biol Chem 276:2571-2575.
    • (2001) J Biol Chem , vol.276 , pp. 2571-2575
    • Di Lisa, F.1    Menabo, R.2    Canton, M.3    Barile, M.4    Bernardi, P.5
  • 22
    • 0037972522 scopus 로고    scopus 로고
    • Mitochondrial respiratory-chain diseases
    • DiMauro S, Schon EA. 2003. Mitochondrial respiratory-chain diseases. N Engl J Med 348:2656-2668.
    • (2003) N Engl J Med , vol.348 , pp. 2656-2668
    • DiMauro, S.1    Schon, E.A.2
  • 27
    • 0032053197 scopus 로고    scopus 로고
    • Oxygen sensitivity of mitochondrial redox status and evoked potential recovery early during reperfusion in post-ischemic rat brain
    • Feng ZC, Sick TJ, Rosenthal M. 1998. Oxygen sensitivity of mitochondrial redox status and evoked potential recovery early during reperfusion in post-ischemic rat brain. Resuscitation 37:33-41.
    • (1998) Resuscitation , vol.37 , pp. 33-41
    • Feng, Z.C.1    Sick, T.J.2    Rosenthal, M.3
  • 28
    • 0033510014 scopus 로고    scopus 로고
    • Mitochondria in neurodegeneration: Acute ischemia and chronic neurodegenerative diseases
    • Fiskum G, Murphy AN, Beal MF. 1999. Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases. J Cereb Blood Flow Metab 19:351-369.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 351-369
    • Fiskum, G.1    Murphy, A.N.2    Beal, M.F.3
  • 29
    • 0036479054 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in acute neurodegeneration
    • Friberg H, Wieloch T. 2002. Mitochondrial permeability transition in acute neurodegeneration. Biochimie 84:241-250.
    • (2002) Biochimie , vol.84 , pp. 241-250
    • Friberg, H.1    Wieloch, T.2
  • 30
    • 18444400187 scopus 로고    scopus 로고
    • Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis
    • Germain M, Mathai JP, McBride HM, Shore GC. 2005. Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis. EMBO J 24:1546-1556.
    • (2005) EMBO J , vol.24 , pp. 1546-1556
    • Germain, M.1    Mathai, J.P.2    McBride, H.M.3    Shore, G.C.4
  • 31
    • 0025292743 scopus 로고
    • Mechanisms by which mitochondria transport calcium
    • Gunter TE, Pfeiffer DR. 1990. Mechanisms by which mitochondria transport calcium. Am J Physiol 258:C755-C786.
    • (1990) Am J Physiol , vol.258
    • Gunter, T.E.1    Pfeiffer, D.R.2
  • 32
    • 0036478989 scopus 로고    scopus 로고
    • The permeability transition pore complex: Another view
    • Halestrap AP, McStay GP, Clarke SJ. 2002. The permeability transition pore complex: another view. Biochimie 84:153-166.
    • (2002) Biochimie , vol.84 , pp. 153-166
    • Halestrap, A.P.1    McStay, G.P.2    Clarke, S.J.3
  • 34
    • 26844487515 scopus 로고    scopus 로고
    • Induction of mitochondrial oxidative stress in astrocytes by nitric oxide precedes disruption of energy metabolism
    • Jacobson J, Duchen MR, Hothersall J, Clark JB, Heales SJ. 2005. Induction of mitochondrial oxidative stress in astrocytes by nitric oxide precedes disruption of energy metabolism. J Neurochem 95:388-395.
    • (2005) J Neurochem , vol.95 , pp. 388-395
    • Jacobson, J.1    Duchen, M.R.2    Hothersall, J.3    Clark, J.B.4    Heales, S.J.5
  • 35
    • 33947594045 scopus 로고    scopus 로고
    • Anoxia-induced changes in pyridine nucleotide redox state in cortical neurons and astrocytes
    • Kahraman S, Fiskum G. 2007. Anoxia-induced changes in pyridine nucleotide redox state in cortical neurons and astrocytes. Neurochem Res 32:799-806.
    • (2007) Neurochem Res , vol.32 , pp. 799-806
    • Kahraman, S.1    Fiskum, G.2
  • 36
    • 0346655211 scopus 로고    scopus 로고
    • BH3-only protein noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1α
    • Kim JY, Ahn HJ, Ryu JH, Suk K, Park JH. 2004a. BH3-only protein noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1α. J Exp Med 199:113-124.
    • (2004) J Exp Med , vol.199 , pp. 113-124
    • Kim, J.Y.1    Ahn, H.J.2    Ryu, J.H.3    Suk, K.4    Park, J.H.5
  • 37
    • 3042723249 scopus 로고    scopus 로고
    • Bid-cardiolipin interaction at mitochondrial contact site contributes to mitochondrial cristae reorganization and cytochrome c release
    • Kim TH, Zhao Y, Ding WX, Shin JN, He X, Seo YW, Chen J, Rabinowich H, Amoscato AA, Yin XM. 2004b. Bid-cardiolipin interaction at mitochondrial contact site contributes to mitochondrial cristae reorganization and cytochrome c release. Mol Biol Cell 15:3061-3072.
    • (2004) Mol Biol Cell , vol.15 , pp. 3061-3072
    • Kim, T.H.1    Zhao, Y.2    Ding, W.X.3    Shin, J.N.4    He, X.5    Seo, Y.W.6    Chen, J.7    Rabinowich, H.8    Amoscato, A.A.9    Yin, X.M.10
  • 39
    • 2642586389 scopus 로고    scopus 로고
    • Acute ammonia intoxication induces an NMDA receptor-mediated increase in poly(ADP-ribose) polymerase level and NAD metabolism in nuclei of rat brain cells
    • Kosenko E, Montoliu C, Giordano G, Kaminsky Y, Venediktova N, Buryanov Y, Felipo V. 2004. Acute ammonia intoxication induces an NMDA receptor-mediated increase in poly(ADP-ribose) polymerase level and NAD metabolism in nuclei of rat brain cells. J Neurochem 89:1101-1110.
    • (2004) J Neurochem , vol.89 , pp. 1101-1110
    • Kosenko, E.1    Montoliu, C.2    Giordano, G.3    Kaminsky, Y.4    Venediktova, N.5    Buryanov, Y.6    Felipo, V.7
  • 41
    • 3342967838 scopus 로고    scopus 로고
    • Metabolic stages, mitochondria and calcium in hypoxic/ischemic brain damage
    • Kristian T. 2004. Metabolic stages, mitochondria and calcium in hypoxic/ischemic brain damage. Cell Calcium. 36:221-233.
    • (2004) Cell Calcium , vol.36 , pp. 221-233
    • Kristian, T.1
  • 42
    • 0029872044 scopus 로고    scopus 로고
    • Secondary bioenergetic failure after transient focal ischaemia is due to mitochondrial injury
    • Kuroda S, Katsura KI, Tsuchidate R, Siesjo BK. 1996. Secondary bioenergetic failure after transient focal ischaemia is due to mitochondrial injury. Acta Physiol Scand 156:149-150.
    • (1996) Acta Physiol Scand , vol.156 , pp. 149-150
    • Kuroda, S.1    Katsura, K.I.2    Tsuchidate, R.3    Siesjo, B.K.4
  • 43
    • 0025317609 scopus 로고
    • Influence of cerebral ischemia and post-ischemic reperfusion on mitochondrial oxidative phosphorylation
    • Kurup CK, Kumaroo KK, Dutka AJ. 1990. Influence of cerebral ischemia and post-ischemic reperfusion on mitochondrial oxidative phosphorylation. J Bioenerg Biomembr. 22:61-80.
    • (1990) J Bioenerg Biomembr , vol.22 , pp. 61-80
    • Kurup, C.K.1    Kumaroo, K.K.2    Dutka, A.J.3
  • 45
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin MT, Beal MF. 2006. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature. 443:787-795.
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 48
    • 29344434866 scopus 로고    scopus 로고
    • The relevance of mitochondrial membrane topology to mitochondrial function
    • Mannella CA. 2006. The relevance of mitochondrial membrane topology to mitochondrial function. Biochim Biophys Acta 1762:140-147.
    • (2006) Biochim Biophys Acta , vol.1762 , pp. 140-147
    • Mannella, C.A.1
  • 49
    • 33644852484 scopus 로고    scopus 로고
    • Mitochondrial injury measured by proton magnetic resonance spectroscopy in severe head trauma patients
    • Marmarou A, Signoretti S, Fatouros P, Aygok GA, Bullock R. 2005. Mitochondrial injury measured by proton magnetic resonance spectroscopy in severe head trauma patients. Acta Neurochir Suppl 95:149-151.
    • (2005) Acta Neurochir , Issue.SUPPL. 95 , pp. 149-151
    • Marmarou, A.1    Signoretti, S.2    Fatouros, P.3    Aygok, G.A.4    Bullock, R.5
  • 50
    • 0033495895 scopus 로고    scopus 로고
    • Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion
    • Matsumoto S, Friberg H, Ferrand-Drake M, Wieloch T. 1999. Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 19:736-741.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 736-741
    • Matsumoto, S.1    Friberg, H.2    Ferrand-Drake, M.3    Wieloch, T.4
  • 51
    • 33746016268 scopus 로고    scopus 로고
    • Mitochondria: More than just a powerhouse
    • McBride HM, Neuspiel M, Wasiak S. 2006. Mitochondria: more than just a powerhouse. Curr Biol 16:R551-R560.
    • (2006) Curr Biol , vol.16
    • McBride, H.M.1    Neuspiel, M.2    Wasiak, S.3
  • 52
    • 18244376911 scopus 로고    scopus 로고
    • Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy
    • Muruganandham M, Alfieri AA, Matei C, Chen Y, Sukenick G, Schemainda I, Hasmann M, Saltz LB, Koutcher JA. 2005. Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy. Clin Cancer Res 11:3503-3513.
    • (2005) Clin Cancer Res , vol.11 , pp. 3503-3513
    • Muruganandham, M.1    Alfieri, A.A.2    Matei, C.3    Chen, Y.4    Sukenick, G.5    Schemainda, I.6    Hasmann, M.7    Saltz, L.B.8    Koutcher, J.A.9
  • 54
    • 0038582584 scopus 로고    scopus 로고
    • Role of superoxide in poly(ADP-ribose) polymerase upregulation after transient cerebral ischemia
    • Narasimhan P, Fujimura M, Noshita N, Chan PH. 2003. Role of superoxide in poly(ADP-ribose) polymerase upregulation after transient cerebral ischemia. Brain Res Mol Brain Res 113:28-36.
    • (2003) Brain Res Mol Brain Res , vol.113 , pp. 28-36
    • Narasimhan, P.1    Fujimura, M.2    Noshita, N.3    Chan, P.H.4
  • 55
    • 0033509493 scopus 로고    scopus 로고
    • An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury
    • Okonkwo DO, Povlishock JT. 1999. An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury. J Cereb Blood Flow Metab 19:443-451.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 443-451
    • Okonkwo, D.O.1    Povlishock, J.T.2
  • 56
    • 0030975953 scopus 로고    scopus 로고
    • Release of mitochondrial aspartate aminotransferase (mAST) following transient focal cerebral ischemia suggests the opening of a mitochondrial permeability transition pore
    • Ouyang Y-B, Kuroda S, Kristian T, Siesjo BK. 1997. Release of mitochondrial aspartate aminotransferase (mAST) following transient focal cerebral ischemia suggests the opening of a mitochondrial permeability transition pore. Neurosci Res Commun 20:167-173.
    • (1997) Neurosci Res Commun , vol.20 , pp. 167-173
    • Ouyang, Y.-B.1    Kuroda, S.2    Kristian, T.3    Siesjo, B.K.4
  • 57
    • 33745742159 scopus 로고    scopus 로고
    • Mitochondrial fission and apoptosis: An ongoing trial
    • Parone PA, Martinou JC. 2006. Mitochondrial fission and apoptosis: an ongoing trial. Biochim Biophys Acta 1763:522-530.
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 522-530
    • Parone, P.A.1    Martinou, J.C.2
  • 58
    • 0345084491 scopus 로고    scopus 로고
    • Calcium influx from the extracellular space promotes NADH hyperoxidation and electrical dysfunction after anoxia in hippocampal slices
    • Perez-Pinzon MA, Mumford PL, Carranza V, Sick TJ. 1998. Calcium influx from the extracellular space promotes NADH hyperoxidation and electrical dysfunction after anoxia in hippocampal slices. J Cereb Blood Flow Metab 18:215-221.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 215-221
    • Perez-Pinzon, M.A.1    Mumford, P.L.2    Carranza, V.3    Sick, T.J.4
  • 59
    • 0343247698 scopus 로고    scopus 로고
    • Antioxidants, mitochondrial hyperoxidation and electrical recovery after anoxia in hippocampal slices
    • Perez-Pinzon MA, Mumford PL, Rosenthal M, Sick TJ. 1997. Antioxidants, mitochondrial hyperoxidation and electrical recovery after anoxia in hippocampal slices. Brain Res 754:163-170.
    • (1997) Brain Res , vol.754 , pp. 163-170
    • Perez-Pinzon, M.A.1    Mumford, P.L.2    Rosenthal, M.3    Sick, T.J.4
  • 60
    • 0035851110 scopus 로고    scopus 로고
    • BH3 death domain peptide induces cell type-selective mitochondrial outer membrane permeability
    • Polster BM, Kinnally KW, Fiskum G. 2001. BH3 death domain peptide induces cell type-selective mitochondrial outer membrane permeability. J Biol Chem 276:37887-37894.
    • (2001) J Biol Chem , vol.276 , pp. 37887-37894
    • Polster, B.M.1    Kinnally, K.W.2    Fiskum, G.3
  • 64
    • 1242314873 scopus 로고    scopus 로고
    • Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampus
    • Schmidt-Kastner R, Aguirre-Chen C, Kietzmann T, Saul I, Busto R, Ginsberg MD. 2004. Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampus. Brain Res 1001:133-142.
    • (2004) Brain Res , vol.1001 , pp. 133-142
    • Schmidt-Kastner, R.1    Aguirre-Chen, C.2    Kietzmann, T.3    Saul, I.4    Busto, R.5    Ginsberg, M.D.6
  • 66
    • 1842536773 scopus 로고    scopus 로고
    • Rethinking the excitotoxic ionic milieu: The emerging role of Zn(2+) in ischemic neuronal injury
    • Sensi SL, Jeng JM. 2004. Rethinking the excitotoxic ionic milieu: the emerging role of Zn(2+) in ischemic neuronal injury. Curr Mol Med. 4:87-111.
    • (2004) Curr Mol Med , vol.4 , pp. 87-111
    • Sensi, S.L.1    Jeng, J.M.2
  • 68
    • 0034733928 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1: What have we learned from the deficient mouse model?
    • Shall S, de Murcia G. 2000. Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model? Mutat Res 460:1-15.
    • (2000) Mutat Res , vol.460 , pp. 1-15
    • Shall, S.1    de Murcia, G.2
  • 69
    • 33845950074 scopus 로고    scopus 로고
    • The inhibition of mitochondrial complex I (NADH:ubiquinone oxidoreductase) by Zn2+
    • Sharpley MS, Hirst J. 2006. The inhibition of mitochondrial complex I (NADH:ubiquinone oxidoreductase) by Zn2+. J Biol Chem 281:34803-34809.
    • (2006) J Biol Chem , vol.281 , pp. 34803-34809
    • Sharpley, M.S.1    Hirst, J.2
  • 70
    • 0038673321 scopus 로고    scopus 로고
    • NAD(P)H fluorescence imaging of postsynaptic neuronal activation in murine hippocampal slices
    • Shuttleworth CW, Brennan AM, Connor JA. 2003. NAD(P)H fluorescence imaging of postsynaptic neuronal activation in murine hippocampal slices. J Neurosci 23:3196-3208.
    • (2003) J Neurosci , vol.23 , pp. 3196-3208
    • Shuttleworth, C.W.1    Brennan, A.M.2    Connor, J.A.3
  • 71
    • 0036192440 scopus 로고    scopus 로고
    • Ultrastructural changes of neuronal mitochondria after transient and permanent cerebral ischemia
    • Solenski NJ, diPierro CG, Trimmer PA, Kwan AL, Helm GA. 2002. Ultrastructural changes of neuronal mitochondria after transient and permanent cerebral ischemia. Stroke 33:816-824.
    • (2002) Stroke , vol.33 , pp. 816-824
    • Solenski, N.J.1    diPierro, C.G.2    Trimmer, P.A.3    Kwan, A.L.4    Helm, G.A.5
  • 72
    • 0036788941 scopus 로고    scopus 로고
    • Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax
    • Starkov AA, Polster BM, Fiskum G. 2002. Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax. J Neurochem 83:220-228.
    • (2002) J Neurochem , vol.83 , pp. 220-228
    • Starkov, A.A.1    Polster, B.M.2    Fiskum, G.3
  • 73
    • 0344011439 scopus 로고    scopus 로고
    • Hypoglycemic neuronal death and cognitive impairment are prevented by poly(ADP-ribose) polymerase inhibitors administered after hypoglycemia
    • Suh SW, Aoyama K, Chen Y, Garnier P, Matsumori Y, Gum E, Liu J, Swanson RA. 2003. Hypoglycemic neuronal death and cognitive impairment are prevented by poly(ADP-ribose) polymerase inhibitors administered after hypoglycemia. J Neurosci 23:10681-10690.
    • (2003) J Neurosci , vol.23 , pp. 10681-10690
    • Suh, S.W.1    Aoyama, K.2    Chen, Y.3    Garnier, P.4    Matsumori, Y.5    Gum, E.6    Liu, J.7    Swanson, R.A.8
  • 74
    • 0034057187 scopus 로고    scopus 로고
    • Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury
    • Sullivan PG, Thompson M, Scheff SW. 2000. Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury. Exp Neurol 161:631-637.
    • (2000) Exp Neurol , vol.161 , pp. 631-637
    • Sullivan, P.G.1    Thompson, M.2    Scheff, S.W.3
  • 75
    • 12244281831 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in CNS trauma: Cause or effect of neuronal cell death?
    • Sullivan PG, Rabchevsky AG, Waldmeier PC, Springer JE. 2005. Mitochondrial permeability transition in CNS trauma: cause or effect of neuronal cell death? J Neurosci Res 79:231-239.
    • (2005) J Neurosci Res , vol.79 , pp. 231-239
    • Sullivan, P.G.1    Rabchevsky, A.G.2    Waldmeier, P.C.3    Springer, J.E.4
  • 76
    • 0032127666 scopus 로고    scopus 로고
    • Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion
    • Szabo C, Dawson VL. 1998. Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion. Trends Pharmacol Sci 19:287-298.
    • (1998) Trends Pharmacol Sci , vol.19 , pp. 287-298
    • Szabo, C.1    Dawson, V.L.2
  • 77
    • 25644443963 scopus 로고    scopus 로고
    • Mitochondrial impairment induced by poly(ADP-ribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation
    • Tanaka S, Takehashi M, Iida S, Kitajima T, Kamanaka Y, Stedeford T, Banasik M, Ueda K. 2005. Mitochondrial impairment induced by poly(ADP-ribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation. J Neurochem 95:179-190.
    • (2005) J Neurochem , vol.95 , pp. 179-190
    • Tanaka, S.1    Takehashi, M.2    Iida, S.3    Kitajima, T.4    Kamanaka, Y.5    Stedeford, T.6    Banasik, M.7    Ueda, K.8
  • 79
    • 0034671429 scopus 로고    scopus 로고
    • Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of α-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress
    • Tretter L, Adam-Vizi V. 2000. Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of α-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress. J Neurosci 20:8972-8979.
    • (2000) J Neurosci , vol.20 , pp. 8972-8979
    • Tretter, L.1    Adam-Vizi, V.2
  • 80
    • 0029590050 scopus 로고
    • Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat
    • Uchino H, Elmer E, Uchino K, Lindvall O, Siesjo BK. 1995. Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat. Acta Physiol Scand 155:469-471.
    • (1995) Acta Physiol Scand , vol.155 , pp. 469-471
    • Uchino, H.1    Elmer, E.2    Uchino, K.3    Lindvall, O.4    Siesjo, B.K.5
  • 81
    • 0036403825 scopus 로고    scopus 로고
    • Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition
    • Uchino H, Minamikawa-Tachino R, Kristian T, Perkins G, Narazaki M, Siesjo BK, Shibasaki F. 2002. Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition. Neurobiol Dis 10:219-233.
    • (2002) Neurobiol Dis , vol.10 , pp. 219-233
    • Uchino, H.1    Minamikawa-Tachino, R.2    Kristian, T.3    Perkins, G.4    Narazaki, M.5    Siesjo, B.K.6    Shibasaki, F.7
  • 82
    • 0035380462 scopus 로고    scopus 로고
    • Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane
    • Vander Heiden MG, Li XX, Gottleib E, Hill RB, Thompson CB, Colombini M. 2001. Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. J Biol Chem 276:19414-19419.
    • (2001) J Biol Chem , vol.276 , pp. 19414-19419
    • Vander Heiden, M.G.1    Li, X.X.2    Gottleib, E.3    Hill, R.B.4    Thompson, C.B.5    Colombini, M.6
  • 84
    • 33644688266 scopus 로고    scopus 로고
    • Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons
    • Vesce S, Jekabsons MB, Johnson-Cadwell LI, Nicholls DG. 2005. Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons. J Biol Chem 280:38720-38728.
    • (2005) J Biol Chem , vol.280 , pp. 38720-38728
    • Vesce, S.1    Jekabsons, M.B.2    Johnson-Cadwell, L.I.3    Nicholls, D.G.4
  • 85
    • 21644450243 scopus 로고    scopus 로고
    • Conformational dependence of intracellular NADH on metabolic state revealed by associated fluorescence anisotropy
    • Vishwasrao HD, Heikal AA, Kasischke KA, Webb WW. 2005. Conformational dependence of intracellular NADH on metabolic state revealed by associated fluorescence anisotropy. J Biol Chem 280:25119-25126.
    • (2005) J Biol Chem , vol.280 , pp. 25119-25126
    • Vishwasrao, H.D.1    Heikal, A.A.2    Kasischke, K.A.3    Webb, W.W.4
  • 86
    • 23644433329 scopus 로고    scopus 로고
    • The mitochondrial genome in human adaptive radiation and disease: On the road to therapeutics and performance enhancement
    • Wallace DC. 2005. The mitochondrial genome in human adaptive radiation and disease: on the road to therapeutics and performance enhancement. Gene. 354:169-180.
    • (2005) Gene , vol.354 , pp. 169-180
    • Wallace, D.C.1
  • 87
    • 26444593029 scopus 로고    scopus 로고
    • Mitochondria and endoplasmic reticulum: The lethal interorganelle cross-talk
    • Walter L, Hajnoczky G. 2005. Mitochondria and endoplasmic reticulum: the lethal interorganelle cross-talk. J Bioenerg Biomembr 37:191-206.
    • (2005) J Bioenerg Biomembr , vol.37 , pp. 191-206
    • Walter, L.1    Hajnoczky, G.2
  • 88
    • 0020326533 scopus 로고
    • Columnar alterations of NADH fluorescence during hypoxia-ischemia in immature rat brain
    • Welsh FA, Vannucci RC, Brierley JB. 1982. Columnar alterations of NADH fluorescence during hypoxia-ischemia in immature rat brain. J Cereb Blood Flow Metab 2:221-228.
    • (1982) J Cereb Blood Flow Metab , vol.2 , pp. 221-228
    • Welsh, F.A.1    Vannucci, R.C.2    Brierley, J.B.3
  • 89
    • 0032387842 scopus 로고
    • Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition
    • Woodfield K, Ruck A, Brdiczka D, Halestrap AP. 1988. Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition. Biochem J 336:287-290.
    • (1988) Biochem J , vol.336 , pp. 287-290
    • Woodfield, K.1    Ruck, A.2    Brdiczka, D.3    Halestrap, A.P.4
  • 91
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW. 2004. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 23:2369-2380.
    • (2004) EMBO J , vol.23 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6    Mayo, M.W.7
  • 92
    • 33744480316 scopus 로고    scopus 로고
    • NAD+ and NADH in cellular functions and cell death
    • Ying W. 2006. NAD+ and NADH in cellular functions and cell death. Front Biosci 11:3129-3148.
    • (2006) Front Biosci , vol.11 , pp. 3129-3148
    • Ying, W.1
  • 93
    • 0033612939 scopus 로고    scopus 로고
    • Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia
    • Yoshimoto T, Siesjo BK. 1999. Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia. Brain Res 839:283-291.
    • (1999) Brain Res , vol.839 , pp. 283-291
    • Yoshimoto, T.1    Siesjo, B.K.2
  • 95
    • 33644552417 scopus 로고    scopus 로고
    • Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology
    • Yu T, Robotham JL, Yoon Y. 2006. Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology. Proc Natl Acad Sci U S A 103:2653-2658.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2653-2658
    • Yu, T.1    Robotham, J.L.2    Yoon, Y.3
  • 96
    • 33847012075 scopus 로고    scopus 로고
    • Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons
    • Yuan H, Gerencser AA, Liot G, Lipton SA, EUisman M, Perkins GA, Bossy-Wetzel E. 2007. Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons. Cell Death Differ 14:462-471.
    • (2007) Cell Death Differ , vol.14 , pp. 462-471
    • Yuan, H.1    Gerencser, A.A.2    Liot, G.3    Lipton, S.A.4    EUisman, M.5    Perkins, G.A.6    Bossy-Wetzel, E.7
  • 97
    • 0030296307 scopus 로고    scopus 로고
    • Alterations in the glutathione content of mitochondria following short-term forebrain ischemia in rats
    • Zaidan E, Sims NR. 1996. Alterations in the glutathione content of mitochondria following short-term forebrain ischemia in rats. Neurosci Lett 218:75-78.
    • (1996) Neurosci Lett , vol.218 , pp. 75-78
    • Zaidan, E.1    Sims, N.R.2
  • 98
    • 0032720041 scopus 로고    scopus 로고
    • Cyclosporin A-sensitive changes in mitochondrial glutathione are an early response to intrastiatal NMDA or forebrain ischemia in rats
    • Zaidan E, Nilsson M, Sims NR. 1999. Cyclosporin A-sensitive changes in mitochondrial glutathione are an early response to intrastiatal NMDA or forebrain ischemia in rats. J Neurochem 73:2214-2217.
    • (1999) J Neurochem , vol.73 , pp. 2214-2217
    • Zaidan, E.1    Nilsson, M.2    Sims, N.R.3
  • 99
    • 0035229427 scopus 로고    scopus 로고
    • The mitochondrion in apoptosis: How Pandora's box opens
    • Zamzami N, Kroemer G. 2001. The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol 2:67-71.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 67-71
    • Zamzami, N.1    Kroemer, G.2
  • 100
    • 33645840444 scopus 로고    scopus 로고
    • Nitric oxide impairs mitochondrial movement in cortical neurons during hypoxia
    • Zanelli SA, Trimmer PA, Solenski NJ. 2006. Nitric oxide impairs mitochondrial movement in cortical neurons during hypoxia. J Neurochem 97:724-736.
    • (2006) J Neurochem , vol.97 , pp. 724-736
    • Zanelli, S.A.1    Trimmer, P.A.2    Solenski, N.J.3
  • 101
    • 33846404132 scopus 로고    scopus 로고
    • Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices
    • Zeng J, Yang GY, Ying W, Kelly M, Hirai K, James TL, Swanson RA, Litt L. 2007. Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices. J Cereb Blood Flow Metab 27:304-315.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 304-315
    • Zeng, J.1    Yang, G.Y.2    Ying, W.3    Kelly, M.4    Hirai, K.5    James, T.L.6    Swanson, R.A.7    Litt, L.8
  • 102
    • 0028294246 scopus 로고
    • Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
    • Zhang J, Dawson VL, Dawson TM, Snyder SH. 1994. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263:687-689.
    • (1994) Science , vol.263 , pp. 687-689
    • Zhang, J.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4
  • 103
    • 0034023238 scopus 로고    scopus 로고
    • New functions of a long-known molecule. Emerging roles of NAD in cellular signaling
    • Ziegler M. 2000. New functions of a long-known molecule. Emerging roles of NAD in cellular signaling. Eur J Biochem 267:1550-1564.
    • (2000) Eur J Biochem , vol.267 , pp. 1550-1564
    • Ziegler, M.1
  • 104
    • 0029116916 scopus 로고
    • The mitochondrial permeability transition
    • Zoratti M, Szabo I. 1995. The mitochondrial permeability transition. Biochim Biophys Acta 1241:139-176.
    • (1995) Biochim Biophys Acta , vol.1241 , pp. 139-176
    • Zoratti, M.1    Szabo, I.2


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