메뉴 건너뛰기




Volumn 48, Issue 2, 1997, Pages 143-148

Deleterious network hypothesis of aging

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; FREE RADICAL;

EID: 0031081488     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(97)90281-4     Document Type: Article
Times cited : (31)

References (71)
  • 1
    • 0026047662 scopus 로고
    • The aging process: Major risk factor for disease and death
    • Harman D. The aging process: major risk factor for disease and death. Proc Natl Acad Sci USA 1991; 88: 5360-5363.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5360-5363
    • Harman, D.1
  • 2
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol 1956; 11: 298-300.
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 3
    • 0026775958 scopus 로고
    • Free radical theory of aging
    • Harman D. Free radical theory of aging. Mutat Res 1992; 275: 257-266.
    • (1992) Mutat Res , vol.275 , pp. 257-266
    • Harman, D.1
  • 6
    • 0022339852 scopus 로고
    • Hypothesis: Glucose as a mediator of aging
    • Cerami A. Hypothesis: glucose as a mediator of aging. J Am Geriatr Soc 1985; 33: 626-634.
    • (1985) J Am Geriatr Soc , vol.33 , pp. 626-634
    • Cerami, A.1
  • 7
    • 0025373091 scopus 로고
    • Nonenzymatic glycosylation, the Maillard reaction and the aging process
    • Monnier V M. Nonenzymatic glycosylation, the Maillard reaction and the aging process. J Gerontol 1990; 45: B105-B111.
    • (1990) J Gerontol , vol.45
    • Monnier, V.M.1
  • 8
    • 0002502956 scopus 로고
    • Towards theories of brain aging
    • Kay D W, Burrows G D, eds. Amsterdam: Elsevier
    • Khachaturian Z. Towards theories of brain aging. In: Kay D W, Burrows G D, eds. Handbook of Studies on Psychiatry and Old Age. Amsterdam: Elsevier, 1984: 7-30.
    • (1984) Handbook of Studies on Psychiatry and Old Age , pp. 7-30
    • Khachaturian, Z.1
  • 9
    • 0026743031 scopus 로고
    • Reactive oxygen and DNA damage in mitochondria
    • Richter C. Reactive oxygen and DNA damage in mitochondria. Mutat Res 1992; 275: 249-255.
    • (1992) Mutat Res , vol.275 , pp. 249-255
    • Richter, C.1
  • 10
    • 0025981361 scopus 로고
    • Protein, lipid, and DNA repair systems in oxidative stress: The free-radical theory of aging revisited
    • Pacifici R E, Davies K J A. Protein, lipid, and DNA repair systems in oxidative stress: the free-radical theory of aging revisited. Gerontology 1991; 37: 166-180.
    • (1991) Gerontology , vol.37 , pp. 166-180
    • Pacifici, R.E.1    Davies, K.J.A.2
  • 11
    • 0028217730 scopus 로고
    • Inherited enhancement of hydroxyl radical generation and lipid peroxidation in the S strain rats results in DNA rearrangements, degenerative diseases, and premature aging
    • Salganik R I, Solovyova N A, Dikalov S I, Grishaeva O N, Semenova L A, Popovsky A V. Inherited enhancement of hydroxyl radical generation and lipid peroxidation in the S strain rats results in DNA rearrangements, degenerative diseases, and premature aging. Biochem Biophys Res Commun 1994; 199: 726-733.
    • (1994) Biochem Biophys Res Commun , vol.199 , pp. 726-733
    • Salganik, R.I.1    Solovyova, N.A.2    Dikalov, S.I.3    Grishaeva, O.N.4    Semenova, L.A.5    Popovsky, A.V.6
  • 12
    • 0029417023 scopus 로고
    • Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro
    • Busciglio J, Yankner B A. Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro. Nature 1995; 378: 776-779.
    • (1995) Nature , vol.378 , pp. 776-779
    • Busciglio, J.1    Yankner, B.A.2
  • 13
    • 0025981745 scopus 로고
    • Water and ion distributions in myocytes cultured under oxidative stress mimic changes found in the process of aging
    • von Zglinicki T, Marzabadi M R, Roomans G M. Water and ion distributions in myocytes cultured under oxidative stress mimic changes found in the process of aging. Mech Ageing Dev 1991; 58: 49-60.
    • (1991) Mech Ageing Dev , vol.58 , pp. 49-60
    • Von Zglinicki, T.1    Marzabadi, M.R.2    Roomans, G.M.3
  • 14
    • 0004437641 scopus 로고
    • Peroxide-producing potential of tissues: Inverse correlation with longevity of mammalian species
    • Cutler R G. Peroxide-producing potential of tissues: inverse correlation with longevity of mammalian species. Proc Natl Acad Sci USA 1985; 82: 4798-4802.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 4798-4802
    • Cutler, R.G.1
  • 15
    • 0024323120 scopus 로고
    • Superoxide anion radical production in different animal species
    • Sohal R S, Svensson I, Sohal B H, Brunk U T. Superoxide anion radical production in different animal species. Mech Ageing Dev 1989; 49: 129-135.
    • (1989) Mech Ageing Dev , vol.49 , pp. 129-135
    • Sohal, R.S.1    Svensson, I.2    Sohal, B.H.3    Brunk, U.T.4
  • 16
    • 0027328852 scopus 로고
    • Protein oxidative damage is associated with life expectancy of houseflies
    • Sohal R S, Agarwal S, Dubey A, Orr W C. Protein oxidative damage is associated with life expectancy of houseflies. Proc Natl Acad Sci USA 1993; 90: 7255-7259.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7255-7259
    • Sohal, R.S.1    Agarwal, S.2    Dubey, A.3    Orr, W.C.4
  • 17
    • 0000098878 scopus 로고
    • Antioxidants, aging, and longevity
    • Pryor W A, ed. Orlando, FL: Academic Press
    • Cutler R G. Antioxidants, aging, and longevity. In: Pryor W A, ed. Free Radicals in Biology, VI. Orlando, FL: Academic Press, 1984: 371-128.
    • (1984) Free Radicals in Biology, VI , pp. 371-1128
    • Cutler, R.G.1
  • 18
    • 0001842798 scopus 로고
    • Free radical theory of aging: Role of free radicals in the origination and evolution of life, aging, and disease processes
    • Johnson J E Jr, Walford R, Harman D, Miquel J, eds. New York: Alan R Liss
    • Harman D. Free radical theory of aging: role of free radicals in the origination and evolution of life, aging, and disease processes. In: Johnson J E Jr, Walford R, Harman D, Miquel J, eds. Free Radicals, Aging, and Degenerative Diseases. New York: Alan R Liss, 1986: 3-49.
    • (1986) Free Radicals, Aging, and Degenerative Diseases , pp. 3-49
    • Harman, D.1
  • 19
    • 0019264856 scopus 로고
    • An approach to free radicals in medicine and biology
    • Del Maestro R F. An approach to free radicals in medicine and biology. Acta Physiol Scand 1980; 492: 153-168.
    • (1980) Acta Physiol Scand , vol.492 , pp. 153-168
    • Del Maestro, R.F.1
  • 20
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
    • Fahn S, Cohen G. The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann Neurol 1992; 32: 804-812.
    • (1992) Ann Neurol , vol.32 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 21
    • 0029806859 scopus 로고    scopus 로고
    • A new hypothesis of neurodegenerative diseases: The deleterious network hypothesis
    • Ying W. A new hypothesis of neurodegenerative diseases: the deleterious network hypothesis. Med Hypotheses 1996; 47: 307-313.
    • (1996) Med Hypotheses , vol.47 , pp. 307-313
    • Ying, W.1
  • 22
    • 0029930021 scopus 로고    scopus 로고
    • Deleterious network hypothesis of Alzheimer's disease
    • Ying W. Deleterious network hypothesis of Alzheimer's disease. Med Hypotheses 1996; 46: 421-428.
    • (1996) Med Hypotheses , vol.46 , pp. 421-428
    • Ying, W.1
  • 23
    • 0028908348 scopus 로고
    • Advanced protein glycosylation in diabetes and aging
    • Brownlee M. Advanced protein glycosylation in diabetes and aging. Annu Rev Med 1995; 46: 223-234.
    • (1995) Annu Rev Med , vol.46 , pp. 223-234
    • Brownlee, M.1
  • 24
    • 0025866697 scopus 로고
    • The role of non-enzymatic glycosylation, transition metals, and free radicals in the formation of collagen aggregates
    • Chace K V, Carubelli R, Nordquist R E. The role of non-enzymatic glycosylation, transition metals, and free radicals in the formation of collagen aggregates. Arch Biochem Biophys 1991; 288: 473-180.
    • (1991) Arch Biochem Biophys , vol.288 , pp. 473-1180
    • Chace, K.V.1    Carubelli, R.2    Nordquist, R.E.3
  • 27
    • 0025309791 scopus 로고
    • Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging?
    • Bandy B, Davison A J. Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? Free Radie Biol Med 1990; 8: 523-539.
    • (1990) Free Radie Biol Med , vol.8 , pp. 523-539
    • Bandy, B.1    Davison, A.J.2
  • 29
    • 0024541837 scopus 로고
    • Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
    • Linnane A W, Marzuki S, Ozawa T, Tanaka M. Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet 1989; 1: 642-645.
    • (1989) Lancet , vol.1 , pp. 642-645
    • Linnane, A.W.1    Marzuki, S.2    Ozawa, T.3    Tanaka, M.4
  • 30
    • 0026671245 scopus 로고
    • Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease
    • Corral-Debrinski M, Shoffner J M, Lott M T, Wallace D C. Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease. Mutat Res 1992; 275: 169-180.
    • (1992) Mutat Res , vol.275 , pp. 169-180
    • Corral-Debrinski, M.1    Shoffner, J.M.2    Lott, M.T.3    Wallace, D.C.4
  • 31
    • 0026587335 scopus 로고
    • Mitochondrial genetics: A paradigm for aging and degenerative diseases?
    • Wallace D C. Mitochondrial genetics: a paradigm for aging and degenerative diseases? Science 1992; 256: 628-632.
    • (1992) Science , vol.256 , pp. 628-632
    • Wallace, D.C.1
  • 32
    • 0030046495 scopus 로고    scopus 로고
    • Mitochondria and diabetes. Genetic, biochemical, and clinical implications of the cellular energy circuit
    • Gerbitz K D, Gempel K, Brdiczka D. Mitochondria and diabetes. Genetic, biochemical, and clinical implications of the cellular energy circuit. Diabetes 1996; 45: 113-126
    • (1996) Diabetes , vol.45 , pp. 113-126
    • Gerbitz, K.D.1    Gempel, K.2    Brdiczka, D.3
  • 33
    • 0026672970 scopus 로고
    • Immunochemical evidence for the presence of advanced glycation end products in human lens proteins and its positive correlation with aging
    • Araki N, Ueno N, Chakrabarti B, Morino Y, Horiuchi S. Immunochemical evidence for the presence of advanced glycation end products in human lens proteins and its positive correlation with aging. J Biol Chem 1992; 267: 10211-10214.
    • (1992) J Biol Chem , vol.267 , pp. 10211-10214
    • Araki, N.1    Ueno, N.2    Chakrabarti, B.3    Morino, Y.4    Horiuchi, S.5
  • 34
    • 0025174842 scopus 로고
    • End-stage renal disease and diabetes catalyze the formation of a pentose-derived crosslink from aging human collagen
    • Sell D R, Monnier V M. End-stage renal disease and diabetes catalyze the formation of a pentose-derived crosslink from aging human collagen. J Clin Invest 1990; 85: 380-384.
    • (1990) J Clin Invest , vol.85 , pp. 380-384
    • Sell, D.R.1    Monnier, V.M.2
  • 35
    • 0028272883 scopus 로고
    • Pathogenic effects of advanced glycosylation: Biochemical, biologic, and clinical implications for diabetes and aging
    • Vlassara H, Bucala R, Striker L. Pathogenic effects of advanced glycosylation: Biochemical, biologic, and clinical implications for diabetes and aging. Lab Invest 1994; 70: 138-150.
    • (1994) Lab Invest , vol.70 , pp. 138-150
    • Vlassara, H.1    Bucala, R.2    Striker, L.3
  • 36
    • 0026522638 scopus 로고
    • Regional differences in insulin receptor function in Werner's syndrome
    • Yamasaki H, Akazawa S, Okuno S et al. Regional differences in insulin receptor function in Werner's syndrome. Diabetes Res Clin Pract 1992; 15: 105-111.
    • (1992) Diabetes Res Clin Pract , vol.15 , pp. 105-111
    • Yamasaki, H.1    Akazawa, S.2    Okuno, S.3
  • 37
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes J W. Role of oxidative stress in development of complications in diabetes. Diabetes 1991; 40: 405-412.
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 38
    • 0025540553 scopus 로고
    • Free radical generation by early glycation products: A mechanism for accelerated atherogenesis in diabetes
    • Mullarkey C J, Edelstein D, Brownlee M. Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochem Biophys Res Commun 1990; 173: 932-939.
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 932-939
    • Mullarkey, C.J.1    Edelstein, D.2    Brownlee, M.3
  • 39
    • 0023221558 scopus 로고
    • Increase in the glycosylated form of erythrocyte Cu-Zn-superoxide dismutase in diabetes and close association of the non-enzymatic glycosylation with the enzyme activity
    • Arai K, Iizuka S, Tada Y, Oikawa K, Taniguchi N. Increase in the glycosylated form of erythrocyte Cu-Zn-superoxide dismutase in diabetes and close association of the non-enzymatic glycosylation with the enzyme activity. Biochim Biophys Acta 1987; 924: 292-296.
    • (1987) Biochim Biophys Acta , vol.924 , pp. 292-296
    • Arai, K.1    Iizuka, S.2    Tada, Y.3    Oikawa, K.4    Taniguchi, N.5
  • 42
    • 0027325597 scopus 로고
    • The erythrocyte calcium pump is inhibited by non-enzymatic glycation: Studies in situ, and with the purified enzyme
    • Gonzalez Flecha L, Castello P R, Caride A J, Gagliardino J J, Rossi J P. The erythrocyte calcium pump is inhibited by non-enzymatic glycation: studies in situ, and with the purified enzyme. Biochem J 1993; 293: 369-375.
    • (1993) Biochem J , vol.293 , pp. 369-375
    • Gonzalez Flecha, L.1    Castello, P.R.2    Caride, A.J.3    Gagliardino, J.J.4    Rossi, J.P.5
  • 43
    • 0028260109 scopus 로고
    • Diabetes mellitus: A disease of abnormal cellular calcium metabolism?
    • Levy J, Gavin J R III, Sowers J R. Diabetes mellitus: a disease of abnormal cellular calcium metabolism? Am J Med 1995; 96: 260-273.
    • (1995) Am J Med , vol.96 , pp. 260-273
    • Levy, J.1    Gavin III, J.R.2    Sowers, J.R.3
  • 44
    • 0027215416 scopus 로고
    • Acceleration of hemoglobin glycation with aging
    • Nakashima K, Nishizaki O, Andoh Y. Acceleration of hemoglobin glycation with aging. Clin Chim Acta 1993; 215: 111-118.
    • (1993) Clin Chim Acta , vol.215 , pp. 111-118
    • Nakashima, K.1    Nishizaki, O.2    Andoh, Y.3
  • 45
    • 0028618458 scopus 로고
    • 2+ regulation in aging neurons
    • 2+ regulation in aging neurons. Ann NY Acad Sci 1994; 747: 407-418.
    • (1994) Ann NY Acad Sci , vol.747 , pp. 407-418
    • Michaelis, M.L.1
  • 47
    • 0024239019 scopus 로고
    • Cellular calcium and atherosclerosis: A brief review
    • Phair R D. Cellular calcium and atherosclerosis: a brief review. Cell Calcium 1988; 9: 275-284.
    • (1988) Cell Calcium , vol.9 , pp. 275-284
    • Phair, R.D.1
  • 48
    • 0028946358 scopus 로고
    • Calcium-mediated cell injury and cell death
    • Trump B F, Berezesky I K. Calcium-mediated cell injury and cell death. FASEB J 1995; 9: 219-228.
    • (1995) FASEB J , vol.9 , pp. 219-228
    • Trump, B.F.1    Berezesky, I.K.2
  • 49
    • 0018636340 scopus 로고
    • Calcium dependence of toxic cell death: A final common pathway
    • Schanne F A, Kane A B, Young E E, Farber J L. Calcium dependence of toxic cell death: a final common pathway. Science 1979; 206: 700-702.
    • (1979) Science , vol.206 , pp. 700-702
    • Schanne, F.A.1    Kane, A.B.2    Young, E.E.3    Farber, J.L.4
  • 50
    • 0029000138 scopus 로고
    • Neurochemical changes related to ageing in the senescence-accelerated mouse brain and the effect of chronic administration of nimodipine
    • Kabuto H, Yokoi I, Mori A, Murakami M, Sawada S. Neurochemical changes related to ageing in the senescence-accelerated mouse brain and the effect of chronic administration of nimodipine. Mech Ageing Dev 1995; 80: 1-9.
    • (1995) Mech Ageing Dev , vol.80 , pp. 1-9
    • Kabuto, H.1    Yokoi, I.2    Mori, A.3    Murakami, M.4    Sawada, S.5
  • 51
    • 0027308673 scopus 로고
    • Nimodipine: Cognition, aging, and degeneration
    • de Jonge M C, Traber J. Nimodipine: cognition, aging, and degeneration. Clin Neuropharmacol 1993; 16 (Suppl 1): S25-S30.
    • (1993) Clin Neuropharmacol , vol.16 , Issue.1 SUPPL.
    • De Jonge, M.C.1    Traber, J.2
  • 53
    • 0026276663 scopus 로고
    • The glucocorticoid hypothesis of brain aging and neurodegeneration: Recent modifications
    • Landfield P W, Eldridge J C. The glucocorticoid hypothesis of brain aging and neurodegeneration: recent modifications. Acta Endocrinologica 1991; 125 (suppl 1): 54-64.
    • (1991) Acta Endocrinologica , vol.125 , Issue.1 SUPPL. , pp. 54-64
    • Landfield, P.W.1    Eldridge, J.C.2
  • 54
    • 0028214727 scopus 로고
    • Suppression of calcium-dependent membrane currents in human fibroblasts by replicative senescence and forced expression of a gene sequence encoding a putative calcium-binding protein
    • Liu S, Thweatt R, Lumpkin C K Jr, Goldstein S. Suppression of calcium-dependent membrane currents in human fibroblasts by replicative senescence and forced expression of a gene sequence encoding a putative calcium-binding protein. Proc Natl Acad Sci USA 1994; 91: 2186-2190.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2186-2190
    • Liu, S.1    Thweatt, R.2    Lumpkin Jr., C.K.3    Goldstein, S.4
  • 55
    • 0026779315 scopus 로고
    • A novel gene encoding a smooth muscle protein is overexpressed in senescent human fibroblasts
    • Thweatt R, Lumpkin C K Jr, Goldstein S. A novel gene encoding a smooth muscle protein is overexpressed in senescent human fibroblasts. Biochem Biophys Res Commun 1992; 187: 1-7.
    • (1992) Biochem Biophys Res Commun , vol.187 , pp. 1-7
    • Thweatt, R.1    Lumpkin Jr., C.K.2    Goldstein, S.3
  • 56
    • 0026570528 scopus 로고
    • β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • Mattson M P, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel R E. β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 1992; 12: 376-389.
    • (1992) J Neurosci , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Lieberburg, I.5    Rydel, R.E.6
  • 57
    • 13344293701 scopus 로고    scopus 로고
    • Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome
    • Teller J K, Russo C, DeBusk L M et al. Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome. Nat Med 1996; 2(1): 93-95.
    • (1996) Nat Med , vol.2 , Issue.1 , pp. 93-95
    • Teller, J.K.1    Russo, C.2    DeBusk, L.M.3
  • 58
    • 0028899724 scopus 로고
    • Quantitive analysis of senile plaques in Alzheimer's disease: Observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome)
    • Hyman B T, West H L, Rebeck G W et al. Quantitive analysis of senile plaques in Alzheimer's disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome). Proc Natl Acad Sci USA 1995; 92: 3586-3590.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3586-3590
    • Hyman, B.T.1    West, H.L.2    Rebeck, G.W.3
  • 59
    • 0024428429 scopus 로고
    • Mechanism of insulin resistance induced by sustained levels of cytosolic free calcium in rat adipocytes
    • Draznin B, Lewis D, Houlder N, Sherman N, Adamo M, Garvey W T. Mechanism of insulin resistance induced by sustained levels of cytosolic free calcium in rat adipocytes. Endocrinology 1989; 125: 2341-2349.
    • (1989) Endocrinology , vol.125 , pp. 2341-2349
    • Draznin, B.1    Lewis, D.2    Houlder, N.3    Sherman, N.4    Adamo, M.5    Garvey, W.T.6
  • 60
    • 0028035077 scopus 로고
    • Glutathione regeneration in calcium-loaded erythrocytes: A possible relationship among calcium accumulation, ATP decrement and oxidative damage
    • Kurata M, Suzuki M. Glutathione regeneration in calcium-loaded erythrocytes: a possible relationship among calcium accumulation, ATP decrement and oxidative damage. Comp Biochem Physiol B Biochem Mol Biol 1994; 109: 305-312.
    • (1994) Comp Biochem Physiol B Biochem Mol Biol , vol.109 , pp. 305-312
    • Kurata, M.1    Suzuki, M.2
  • 61
    • 0019490189 scopus 로고
    • Free radical polymerization and lipid binding of lysozyme reacted with peroxidizing linoleic acid
    • Funes J, Karel M. Free radical polymerization and lipid binding of lysozyme reacted with peroxidizing linoleic acid. Lipids 1981; 16: 347-350.
    • (1981) Lipids , vol.16 , pp. 347-350
    • Funes, J.1    Karel, M.2
  • 63
    • 0012304508 scopus 로고
    • Aging of animals: Possible mechanisms
    • Englewood Cliff, NJ: Prentice-Hall
    • Kohn R R. Aging of animals: possible mechanisms. In: Principles of Mammalian Aging, 2nd edn. Englewood Cliff, NJ: Prentice-Hall, 1978.
    • (1978) Principles of Mammalian Aging, 2nd Edn.
    • Kohn, R.R.1
  • 64
    • 0012531790 scopus 로고
    • Oxidative DNA damage as related to cancer and aging: Assay of thymine glycol, thymidine glycol, and hydroxymethyluracil in human and rat urine
    • Sohal R S et al. New York: Raven Press
    • Ames B N, Saul R L, Schwiers E, Adelman R, Cathcart R. Oxidative DNA damage as related to cancer and aging: assay of thymine glycol, thymidine glycol, and hydroxymethyluracil in human and rat urine. In: Sohal R S et al. Molecular Biology of Aging: Gene Stability and Gene Expression. New York: Raven Press, 1985: 137-144.
    • (1985) Molecular Biology of Aging: Gene Stability and Gene Expression , pp. 137-144
    • Ames, B.N.1    Saul, R.L.2    Schwiers, E.3    Adelman, R.4    Cathcart, R.5
  • 65
    • 0026698068 scopus 로고
    • Oxidative and other DNA damages as the basis of aging: A review
    • Holmes G E, Bernstein C, Bernstein H. Oxidative and other DNA damages as the basis of aging: a review. Mutat Res 1992; 275: 305-315.
    • (1992) Mutat Res , vol.275 , pp. 305-315
    • Holmes, G.E.1    Bernstein, C.2    Bernstein, H.3
  • 66
    • 0017158881 scopus 로고
    • Disulfide bonding in chromatin proteins with age and a suggested mechanism for aging and neoplasia
    • Tas S. Disulfide bonding in chromatin proteins with age and a suggested mechanism for aging and neoplasia. Exp Gerontol 1976; 11: 17-24.
    • (1976) Exp Gerontol , vol.11 , pp. 17-24
    • Tas, S.1
  • 67
    • 0001869453 scopus 로고
    • Free radicals, DNA damage, and aging
    • Warner H R et al. New York: Raven Press
    • Saul R L, Gee P, Ames B N. Free radicals, DNA damage, and aging. In: Warner H R et al. Modern Biological Theories of Aging. New York: Raven Press, 1987: 113-129.
    • (1987) Modern Biological Theories of Aging , pp. 113-129
    • Saul, R.L.1    Gee, P.2    Ames, B.N.3
  • 71
    • 0027519721 scopus 로고
    • The potent free radical scavenger alpha-lipoic acid improves memory in aged mice: Putative relationship to NMDA receptor deficits
    • Stoll S, Hartmann H, Cohen S A, Muller W E. The potent free radical scavenger alpha-lipoic acid improves memory in aged mice: putative relationship to NMDA receptor deficits. Pharmacol Biochem Behav 1993; 46: 799-805.
    • (1993) Pharmacol Biochem Behav , vol.46 , pp. 799-805
    • Stoll, S.1    Hartmann, H.2    Cohen, S.A.3    Muller, W.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.