-
1
-
-
0037135528
-
Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligandinduced endocytosis of the epidermal growth factor receptor
-
Ahn, S., Kim, J., Lucaveche, C. L., Reedy,M. C., Luttrell, L.M., Lefkowitz, R. J., et al. (2002). Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligandinduced endocytosis of the epidermal growth factor receptor. The Journal of Biological Chemistry, 277, 26642-26651.
-
(2002)
The Journal of Biological Chemistry
, vol.277
, pp. 26642-26651
-
-
Ahn, S.1
Kim, J.2
Lucaveche, C.L.3
Reedy, M.C.4
Luttrell, L.M.5
Lefkowitz, R.J.6
-
2
-
-
0033555946
-
Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling
-
Ahn, S., Maudsley, S., Luttrell, L. M., Lefkowitz, R. J., & Daaka, Y. (1999). Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. The Journal of Biological Chemistry, 274, 1185-1188.
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 1185-1188
-
-
Ahn, S.1
Maudsley, S.2
Luttrell, L.M.3
Lefkowitz, R.J.4
Daaka, Y.5
-
3
-
-
4143070533
-
Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor
-
Ahn, S., Shenoy, S. K., Wei, H., & Lefkowitz, R. J. (2004). Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor. The Journal of Biological Chemistry, 279, 35518-35525.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 35518-35525
-
-
Ahn, S.1
Shenoy, S.K.2
Wei, H.3
Lefkowitz, R.J.4
-
4
-
-
0036152858
-
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy
-
Asakura, M., Kitakaze, M., Takashima, S., Liao, Y., Ishikura, F., Yoshinaka, T., et al. (2002). Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy. Nature Medicine, 8, 35-40.
-
(2002)
Nature Medicine
, vol.8
, pp. 35-40
-
-
Asakura, M.1
Kitakaze, M.2
Takashima, S.3
Liao, Y.4
Ishikura, F.5
Yoshinaka, T.6
-
5
-
-
0028040778
-
Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme
-
Authier, F., Rachubinski, R. A., Posner, B. I., & Bergeron, J. J. (1994). Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme. Journal of Biological Chemistry, 269, 3010-3016.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 3010-3016
-
-
Authier, F.1
Rachubinski, R.A.2
Posner, B.I.3
Bergeron, J.J.4
-
6
-
-
34250873547
-
Compartmentalization of signaling-competent epidermal growth factor receptors in endosomes
-
Balbis, A., Parmar, A., Wang, Y., Baquiran, G., & Posner, B. I. (2007). Compartmentalization of signaling-competent epidermal growth factor receptors in endosomes. Endocrinology, 148, 2944-2954.
-
(2007)
Endocrinology
, vol.148
, pp. 2944-2954
-
-
Balbis, A.1
Parmar, A.2
Wang, Y.3
Baquiran, G.4
Posner, B.I.5
-
7
-
-
77951727192
-
Compartmentalization of EGFR in cellular membranes: Role of membrane rafts
-
In Press.
-
Balbis, A., & Posner, B. I. (2010). Compartmentalization of EGFR in cellular membranes: Role of membrane rafts. Journal of Cellular Biochemistry, In Press.
-
(2010)
Journal of Cellular Biochemistry
-
-
Balbis, A.1
Posner, B.I.2
-
8
-
-
68849085894
-
A cell biological view of toll-like receptor function: Regulation through compartmentalization
-
Barton, G. M., & Kagan, J. C. (2009). A cell biological view of toll-like receptor function: Regulation through compartmentalization. Nature Reviews Immunology, 9, 535-542.
-
(2009)
Nature Reviews Immunology
, vol.9
, pp. 535-542
-
-
Barton, G.M.1
Kagan, J.C.2
-
9
-
-
37649023273
-
A beta-arrestin 2 signaling complex mediates lithium action on behavior
-
Beaulieu, J. M., Marion, S., Rodriguiz, R. M., Medvedev, I. O., Sotnikova, T. D., Ghisi, V., et al. (2008). A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell, 132, 125-136.
-
(2008)
Cell
, vol.132
, pp. 125-136
-
-
Beaulieu, J.M.1
Marion, S.2
Rodriguiz, R.M.3
Medvedev, I.O.4
Sotnikova, T.D.5
Ghisi, V.6
-
10
-
-
0041654309
-
Down-regulation of the epidermal growth factor receptor in KB cells is due to receptor internalization and subsequent degradation in lysosomes
-
Beguinot, L., Lyall, R. M., Willingham, M. C., & Pastan, I. (1984). Down-regulation of the epidermal growth factor receptor in KB cells is due to receptor internalization and subsequent degradation in lysosomes. Proceedings of the National Academy of Sciences of the United States of America, 81, 2384-2388.
-
(1984)
Proceedings of the National Academy of Sciences of the United States of America
, vol.81
, pp. 2384-2388
-
-
Beguinot, L.1
Lyall, R.M.2
Willingham, M.C.3
Pastan, I.4
-
11
-
-
0018139623
-
Intracellular polypeptide hormone receptors
-
Bergeron, J. J., Posner, B. I., Josefsberg, Z., & Sikstrom, R. (1978). Intracellular polypeptide hormone receptors. The demonstration of specific binding sites for insulin and human growth hormone in Golgi fractions isolated from the liver of female rats. Journal of Biological Chemistry, 253, 4058-4066.
-
(1978)
The demonstration of specific binding sites for insulin and human growth hormone in Golgi fractions isolated from the liver of female rats. Journal of Biological Chemistry
, vol.253
, pp. 4058-4066
-
-
Bergeron, J.J.1
Posner, B.I.2
Josefsberg, Z.3
Sikstrom, R.4
-
12
-
-
0018332643
-
Binding and uptake of 125i-insulin into rat liver hepatocytes and endothelium
-
Bergeron, J. J., Sikstrom, R., Hand, A. R., & Posner, B. I. (1979). Binding and uptake of 125i-insulin into rat liver hepatocytes and endothelium. An in vivo radioautographic study. Journal of Cell Biology, 80, 427-443.
-
(1979)
An in vivo radioautographic study. Journal of Cell Biology
, vol.80
, pp. 427-443
-
-
Bergeron, J.J.1
Sikstrom, R.2
Hand, A.R.3
Posner, B.I.4
-
13
-
-
0028952140
-
Selective activation of the rat hepatic endosomal insulin receptor kinase
-
Bevan, A. P., Burgess, J. W., Drake, P. G., Shaver, A., Bergeron, J. J., & Posner, B. I. (1995a). Selective activation of the rat hepatic endosomal insulin receptor kinase. Role for the endosome in insulin signaling. Journal of Biological Chemistry, 270, 10784-10791.
-
(1995)
Role for the endosome in insulin signaling. Journal of Biological Chemistry
, vol.270
, pp. 10784-10791
-
-
Bevan, A.P.1
Burgess, J.W.2
Drake, P.G.3
Shaver, A.4
Bergeron, J.J.5
Posner, B.I.6
-
14
-
-
0030022183
-
Intracellular signal transduction: The role of endosomes
-
Bevan, A. P., Drake, P. G., Bergeron, J. J., & Posner, B. I. (1996). Intracellular signal transduction: The role of endosomes. Trends in Endocrinology and Metabolism, 7, 13-21.
-
(1996)
Trends in Endocrinology and Metabolism
, vol.7
, pp. 13-21
-
-
Bevan, A.P.1
Drake, P.G.2
Bergeron, J.J.3
Posner, B.I.4
-
15
-
-
0029614706
-
Peroxovanadium compounds: Biological actions and mechanism of insulin-mimesis
-
Bevan, A. P., Drake, P. G., Yale, J. F., Shaver, A., & Posner, B. I. (1995b). Peroxovanadium compounds: Biological actions and mechanism of insulin-mimesis. Molecular & Cellular Biochemistry, 153, 49-58.
-
(1995)
Molecular & Cellular Biochemistry
, vol.153
, pp. 49-58
-
-
Bevan, A.P.1
Drake, P.G.2
Yale, J.F.3
Shaver, A.4
Posner, B.I.5
-
16
-
-
0030869198
-
Trk receptors function as rapid retrograde signal carriers in the adult nervous system
-
Bhattacharyya, A., Watson, F. L., Bradlee, T. A., Pomeroy, S. L., Stiles, C. D., & Segal, R. A. (1997). Trk receptors function as rapid retrograde signal carriers in the adult nervous system. Journal of Neuroscience, 17, 7007-7016.
-
(1997)
Journal of Neuroscience
, vol.17
, pp. 7007-7016
-
-
Bhattacharyya, A.1
Watson, F.L.2
Bradlee, T.A.3
Pomeroy, S.L.4
Stiles, C.D.5
Segal, R.A.6
-
17
-
-
0022978953
-
Structural requirements for the transmembrane activation of the insulin receptor kinase
-
Boni-Schnetzler, M., Rubin, J. B., & Pilch, P. F. (1986). Structural requirements for the transmembrane activation of the insulin receptor kinase. The Journal of Biological Chemistry, 261, 15281-15287.
-
(1986)
The Journal of Biological Chemistry
, vol.261
, pp. 15281-15287
-
-
Boni-Schnetzler, M.1
Rubin, J.B.2
Pilch, P.F.3
-
18
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray, S. J. (2006). Notch signalling: A simple pathway becomes complex. Nature Reviews Molecular Cell Biology, 7, 678-689.
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
-
19
-
-
52649160344
-
EGFR family: Structure physiology signalling and therapeutic targets
-
Burgess, A. W. (2008). EGFR family: Structure physiology signalling and therapeutic targets. Growth Factors, 26, 263-274.
-
(2008)
Growth Factors
, vol.26
, pp. 263-274
-
-
Burgess, A.W.1
-
20
-
-
69249105154
-
Persistent cAMPsignals triggered by internalized G-protein-coupled receptors
-
Calebiro, D., Nikolaev, V. O., Gagliani, M. C., De Filippis, T., Dees, C., Tacchetti, C., et al. (2009). Persistent cAMPsignals triggered by internalized G-protein-coupled receptors. PLoS Biology, 7, e1000172.
-
(2009)
PLoS Biology
, vol.7
-
-
Calebiro, D.1
Nikolaev, V.O.2
Gagliani, M.C.3
De Filippis, T.4
Dees, C.5
Tacchetti, C.6
-
21
-
-
34548487757
-
Stimulation by ghrelin of p42/p44 mitogen-activated protein kinase through the GHS-R1a receptor: Role of G-proteins and beta-arrestins
-
Camina, J. P., Lodeiro, M., Ischenko, O., Martini, A. C., & Casanueva, F. F. (2007). Stimulation by ghrelin of p42/p44 mitogen-activated protein kinase through the GHS-R1a receptor: Role of G-proteins and beta-arrestins. Journal of Cellular Physiology, 213, 187-200.
-
(2007)
Journal of Cellular Physiology
, vol.213
, pp. 187-200
-
-
Camina, J.P.1
Lodeiro, M.2
Ischenko, O.3
Martini, A.C.4
Casanueva, F.F.5
-
22
-
-
33845316454
-
The V2 vasopressin receptor stimulates ERK1/2 activity independently of heterotrimeric G protein signalling
-
Charest, P. G., Oligny-Longpre, G., Bonin, H., Azzi, M., & Bouvier, M. (2007). The V2 vasopressin receptor stimulates ERK1/2 activity independently of heterotrimeric G protein signalling. Cellular Signalling, 19, 32-41.
-
(2007)
Cellular Signalling
, vol.19
, pp. 32-41
-
-
Charest, P.G.1
Oligny-Longpre, G.2
Bonin, H.3
Azzi, M.4
Bouvier, M.5
-
23
-
-
0028589148
-
Platelet-derived growth factor receptor signals
-
Claesson-Welsh, L. (1994). Platelet-derived growth factor receptor signals. The Journal of Biological Chemistry, 269, 32023-32026.
-
(1994)
The Journal of Biological Chemistry
, vol.269
, pp. 32023-32026
-
-
Claesson-Welsh, L.1
-
24
-
-
0036209874
-
Endocytosis of G protein-coupled receptors: Roles of G protein-coupled receptor kinases and beta-arrestin proteins
-
Claing, A., Laporte, S. A., Caron, M. G., & Lefkowitz, R. J. (2002). Endocytosis of G protein-coupled receptors: Roles of G protein-coupled receptor kinases and beta-arrestin proteins. Progress of Neurobiology, 66, 61-79.
-
(2002)
Progress of Neurobiology
, vol.66
, pp. 61-79
-
-
Claing, A.1
Laporte, S.A.2
Caron, M.G.3
Lefkowitz, R.J.4
-
25
-
-
0030044360
-
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
-
Daub, H., Weiss, F. U., Wallasch, C., & Ullrich, A. (1996). Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature, 379, 557-560.
-
(1996)
Nature
, vol.379
, pp. 557-560
-
-
Daub, H.1
Weiss, F.U.2
Wallasch, C.3
Ullrich, A.4
-
26
-
-
0034718604
-
The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta-arrestin-dependent scaffolding complex
-
Defea, K. A., Vaughn, Z. D., O'Bryan, E. M., Nishijima, D., Dery, O., & Bunnett, N. W. (2000a). The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta-arrestin-dependent scaffolding complex. Proceedings of the National Academy of Sciences of the United States of America, 97, 11086-11091.
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, pp. 11086-11091
-
-
Defea, K.A.1
Vaughn, Z.D.2
O'Bryan, E.M.3
Nishijima, D.4
Dery, O.5
Bunnett, N.W.6
-
27
-
-
0034689003
-
Beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
-
Defea, K. A., Zalevsky, J., Thoma, M. S., Dery, O., Mullins, R. D., & Bunnett, N. W. (2000b). Beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. The Journal of Cell Biology, 148, 1267-1281.
-
(2000)
The Journal of Cell Biology
, vol.148
, pp. 1267-1281
-
-
Defea, K.A.1
Zalevsky, J.2
Thoma, M.S.3
Dery, O.4
Mullins, R.D.5
Bunnett, N.W.6
-
28
-
-
0027965262
-
Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma
-
Di Guglielmo, G. M., Baass, P. C., Ou, W. J., Posner, B. I., & Bergeron, J. J. (1994). Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma. EMBO Journal, 13, 4269-4277.
-
(1994)
EMBO Journal
, vol.13
, pp. 4269-4277
-
-
Di Guglielmo, G.M.1
Baass, P.C.2
Ou, W.J.3
Posner, B.I.4
Bergeron, J.J.5
-
29
-
-
0037598870
-
Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover
-
Di Guglielmo, G. M., Le Roy, C., Goodfellow, A. F., & Wrana, J. L. (2003). Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover. Nature Cell Biology, 5, 410-421.
-
(2003)
Nature Cell Biology
, vol.5
, pp. 410-421
-
-
Di Guglielmo, G.M.1
Le Roy, C.2
Goodfellow, A.F.3
Wrana, J.L.4
-
30
-
-
33846474121
-
G-protein-coupled receptors and cancer
-
Dorsam, R. T., & Gutkind, J. S. (2007). G-protein-coupled receptors and cancer. Nature Reviews Cancer, 7, 79-94.
-
(2007)
Nature Reviews Cancer
, vol.7
, pp. 79-94
-
-
Dorsam, R.T.1
Gutkind, J.S.2
-
31
-
-
0022494971
-
Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose
-
Ellis, L., Clauser, E., Morgan, D. O., Edery, M., Roth, R. A., & Rutter, W. J. (1986). Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose. Cell, 45, 721-732.
-
(1986)
Cell
, vol.45
, pp. 721-732
-
-
Ellis, L.1
Clauser, E.2
Morgan, D.O.3
Edery, M.4
Roth, R.A.5
Rutter, W.J.6
-
32
-
-
0026725764
-
The dephosphorylation of insulin and epidermal growth factor receptors
-
Faure, R., Baquiran, G., Bergeron, J. J., & Posner, B. I. (1992). The dephosphorylation of insulin and epidermal growth factor receptors. Role of endosome-associated phosphotyrosine phosphatase(s). Journal of Biological Chemistry, 267, 11215-11221.
-
(1992)
Role of endosome-associated phosphotyrosine phosphatase(s). Journal of Biological Chemistry
, vol.267
, pp. 11215-11221
-
-
Faure, R.1
Baquiran, G.2
Bergeron, J.J.3
Posner, B.I.4
-
33
-
-
0035101820
-
Evolving concepts in G proteincoupled receptor endocytosis: The role in receptor desensitization and signaling
-
Ferguson, S. S. (2001). Evolving concepts in G proteincoupled receptor endocytosis: The role in receptor desensitization and signaling. Pharmacological Reviews, 53, 1-24.
-
(2001)
Pharmacological Reviews
, vol.53
, pp. 1-24
-
-
Ferguson, S.S.1
-
34
-
-
70349309325
-
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis
-
Ferrandon, S., Feinstein, T. N., Castro, M., Wang, B., Bouley, R., Potts, J. T., et al. (2009). Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. Nature Chemical Biology, 5, 734-742.
-
(2009)
Nature Chemical Biology
, vol.5
, pp. 734-742
-
-
Ferrandon, S.1
Feinstein, T.N.2
Castro, M.3
Wang, B.4
Bouley, R.5
Potts, J.T.6
-
35
-
-
13544264506
-
c-Src regulates clathrin adapter protein 2 interaction with beta-arrestin and the angiotensin II type 1 receptor during clathrinmediated internalization
-
Fessart, D., Simaan, M., & Laporte, S. A. (2005). c-Src regulates clathrin adapter protein 2 interaction with beta-arrestin and the angiotensin II type 1 receptor during clathrinmediated internalization. Molecular Endocrinology, 19, 491-503.
-
(2005)
Molecular Endocrinology
, vol.19
, pp. 491-503
-
-
Fessart, D.1
Simaan, M.2
Laporte, S.A.3
-
36
-
-
34250654452
-
Src-dependent phosphorylation of beta2-adaptin dissociates the beta-arrestin-AP-2 complex
-
Fessart, D., Simaan, M., Zimmerman, B., Comeau, J., Hamdan, F. F., Wiseman, P. W., et al. (2007). Src-dependent phosphorylation of beta2-adaptin dissociates the beta-arrestin-AP-2 complex. Journal of Cell Science, 120, 1723-1732.
-
(2007)
Journal of Cell Science
, vol.120
, pp. 1723-1732
-
-
Fessart, D.1
Simaan, M.2
Zimmerman, B.3
Comeau, J.4
Hamdan, F.F.5
Wiseman, P.W.6
-
37
-
-
33744957160
-
Distinct beta-arrestin-and G proteindependent pathways for parathyroid hormone receptorstimulated ERK1/2 activation
-
Gesty-Palmer, D., Chen, M., Reiter, E., Ahn, S., Nelson, C. D., Wang, S., et al. (2006). Distinct beta-arrestin-and G proteindependent pathways for parathyroid hormone receptorstimulated ERK1/2 activation. The Journal of Biological Chemistry, 281, 10856-10864.
-
(2006)
The Journal of Biological Chemistry
, vol.281
, pp. 10856-10864
-
-
Gesty-Palmer, D.1
Chen, M.2
Reiter, E.3
Ahn, S.4
Nelson, C.D.5
Wang, S.6
-
38
-
-
0029770657
-
Betaarrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor
-
Goodman, O. B. Jr., Krupnick, J. G., Santini, F., Gurevich, V. V., Penn, R. B., Gagnon, A. W., et al. (1996). Betaarrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature, 383, 447-450.
-
(1996)
Nature
, vol.383
, pp. 447-450
-
-
Goodman Jr., O.B.1
Krupnick, J.G.2
Santini, F.3
Gurevich, V.V.4
Penn, R.B.5
Gagnon, A.W.6
-
39
-
-
10544248585
-
Endocytosis of activated TrkA: Evidence that nerve growth factor induces formation of signaling endosomes
-
Grimes, M. L., Zhou, J., Beattie, E. C., Yuen, E. C., Hall, D. E., Valletta, J. S., et al. (1996). Endocytosis of activated TrkA: Evidence that nerve growth factor induces formation of signaling endosomes. Journal of Neuroscience, 16, 7950-7964.
-
(1996)
Journal of Neuroscience
, vol.16
, pp. 7950-7964
-
-
Grimes, M.L.1
Zhou, J.2
Beattie, E.C.3
Yuen, E.C.4
Hall, D.E.5
Valletta, J.S.6
-
40
-
-
33745801153
-
Lipid rafts: Contentious only from simplistic standpoints
-
Hancock, J. F. (2006). Lipid rafts: Contentious only from simplistic standpoints. Nature Reviews Molecular Cell Biology, 7, 456-462.
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, pp. 456-462
-
-
Hancock, J.F.1
-
41
-
-
0037144841
-
TGF beta receptor internalization into EEA1-enriched early endosomes: Role in signaling to smad2
-
Hayes, S., Chawla, A., & Corvera, S. (2002). TGF beta receptor internalization into EEA1-enriched early endosomes: Role in signaling to smad2. The Journal of Cell Biology, 158, 1239-1249.
-
(2002)
The Journal of Cell Biology
, vol.158
, pp. 1239-1249
-
-
Hayes, S.1
Chawla, A.2
Corvera, S.3
-
42
-
-
34247112490
-
Apolipoprotein receptor 2 and X11 alpha/beta mediate apolipoprotein E-induced endocytosis of amyloid-beta precursor protein and beta-secretase, leading to amyloid-beta production
-
He, X., Cooley, K., Chung, C. H., Dashti, N., & Tang, J. (2007). Apolipoprotein receptor 2 and X11 alpha/beta mediate apolipoprotein E-induced endocytosis of amyloid-beta precursor protein and beta-secretase, leading to amyloid-beta production. Journal of Neuroscience, 27, 4052-4060.
-
(2007)
Journal of Neuroscience
, vol.27
, pp. 4052-4060
-
-
He, X.1
Cooley, K.2
Chung, C.H.3
Dashti, N.4
Tang, J.5
-
43
-
-
2542421751
-
Dynein motors transport activated trks to promote survival of targetdependent neurons
-
Heerssen, H. M., Pazyra, M. F., & Segal, R. A. (2004). Dynein motors transport activated trks to promote survival of targetdependent neurons. Nature Neuroscience, 7, 596-604.
-
(2004)
Nature Neuroscience
, vol.7
, pp. 596-604
-
-
Heerssen, H.M.1
Pazyra, M.F.2
Segal, R.A.3
-
44
-
-
2442661614
-
Cathepsin D links TNFinduced acid sphingomyelinase to bid-mediated caspase-9 and -3 activation
-
Heinrich, M., Neumeyer, J., Jakob, M., Hallas, C., Tchikov, V., Winoto-Morbach, S., et al. (2004). Cathepsin D links TNFinduced acid sphingomyelinase to bid-mediated caspase-9 and -3 activation. Cell Death Differential, 11, 550-563.
-
(2004)
Cell Death Differential
, vol.11
, pp. 550-563
-
-
Heinrich, M.1
Neumeyer, J.2
Jakob, M.3
Hallas, C.4
Tchikov, V.5
Winoto-Morbach, S.6
-
45
-
-
0030028790
-
A grb2-associated docking protein in EGF-and insulin-receptor signalling
-
Holgado-Madruga, M., Emlet, D. R., Moscatello, D. K., Godwin, A. K., & Wong, A. J. (1996). A grb2-associated docking protein in EGF-and insulin-receptor signalling. Nature, 379, 560-564.
-
(1996)
Nature
, vol.379
, pp. 560-564
-
-
Holgado-Madruga, M.1
Emlet, D.R.2
Moscatello, D.K.3
Godwin, A.K.4
Wong, A.J.5
-
46
-
-
40749126837
-
Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration
-
Hu, H., Milstein, M., Bliss, J. M., Thai, M., Malhotra, G., Huynh, L. C., et al. (2008). Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration. Molecular and Cellular Biology, 28, 1573-1583.
-
(2008)
Molecular and Cellular Biology
, vol.28
, pp. 1573-1583
-
-
Hu, H.1
Milstein, M.2
Bliss, J.M.3
Thai, M.4
Malhotra, G.5
Huynh, L.C.6
-
47
-
-
36749036679
-
EGF receptor ubiquitination is not necessary for its internalization
-
Huang, F., Goh, L. K., & Sorkin, A. (2007). EGF receptor ubiquitination is not necessary for its internalization. Proceedings of the National Academy of Sciences of the United States of America, 104, 16904-16909.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 16904-16909
-
-
Huang, F.1
Goh, L.K.2
Sorkin, A.3
-
48
-
-
0242290315
-
Tyrosine phosphorylation of the beta2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking
-
Huang, F., Jiang, X., & Sorkin, A. (2003). Tyrosine phosphorylation of the beta2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking. The Journal of Biological Chemistry, 278, 43411-43417.
-
(2003)
The Journal of Biological Chemistry
, vol.278
, pp. 43411-43417
-
-
Huang, F.1
Jiang, X.2
Sorkin, A.3
-
49
-
-
0018417548
-
The uptake of prolactin into female rat liver
-
Josefsberg, Z., Posner, B. I., Patel, B., & Bergeron, J. J. (1979). The uptake of prolactin into female rat liver. Concentration of intact hormone in the Golgi apparatus. Journal of Biological Chemistry, 254, 209-214.
-
(1979)
Concentration of intact hormone in the Golgi apparatus. Journal of Biological Chemistry
, vol.254
, pp. 209-214
-
-
Josefsberg, Z.1
Posner, B.I.2
Patel, B.3
Bergeron, J.J.4
-
50
-
-
0023736417
-
The insulin receptor and the molecular mechanism of insulin action
-
Kahn, C. R., & White, M. F. (1988). The insulin receptor and the molecular mechanism of insulin action. The Journal of Clinical Investigation, 82, 1151-1156.
-
(1988)
The Journal of Clinical Investigation
, vol.82
, pp. 1151-1156
-
-
Kahn, C.R.1
White, M.F.2
-
51
-
-
0023023424
-
Epidermal growth factor receptor kinase translocation and activation in vivo
-
Kay, D. G., Lai, W. H., Uchihashi, M., Khan, M. N., Posner, B. I., & Bergeron, J. J. (1986). Epidermal growth factor receptor kinase translocation and activation in vivo. Journal of Biological Chemistry, 261, 8473-8480.
-
(1986)
Journal of Biological Chemistry
, vol.261
, pp. 8473-8480
-
-
Kay, D.G.1
Lai, W.H.2
Uchihashi, M.3
Khan, M.N.4
Posner, B.I.5
Bergeron, J.J.6
-
52
-
-
51649130231
-
Receptor trafficking controls weak signal delivery: A strategy used by c-Met for STAT3 nuclear accumulation
-
Kermorgant, S., & Parker, P. J. (2008). Receptor trafficking controls weak signal delivery: A strategy used by c-Met for STAT3 nuclear accumulation. The Journal of Cell Biology, 182, 855-863.
-
(2008)
The Journal of Cell Biology
, vol.182
, pp. 855-863
-
-
Kermorgant, S.1
Parker, P.J.2
-
53
-
-
0022997598
-
Characterization of rat liver endosomal fractions
-
Khan, M. N., Savoie, S., Bergeron, J. J., & Posner, B. I. (1986). Characterization of rat liver endosomal fractions. In vivo activation of insulin-stimulable receptor kinase in these structures. Journal of Biological Chemistry, 261, 8462-8472.
-
(1986)
In vivo activation of insulin-stimulable receptor kinase in these structures. Journal of Biological Chemistry
, vol.261
, pp. 8462-8472
-
-
Khan, M.N.1
Savoie, S.2
Bergeron, J.J.3
Posner, B.I.4
-
54
-
-
0031747997
-
The role of receptor kinases and arrestins in G protein-coupled receptor regulation
-
Krupnick, J. G., & Benovic, J. L. (1998). The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annual Review of Pharmacology and Toxicology, 38, 289-319.
-
(1998)
Annual Review of Pharmacology and Toxicology
, vol.38
, pp. 289-319
-
-
Krupnick, J.G.1
Benovic, J.L.2
-
55
-
-
0033616494
-
The beta2-adrenergic receptor/ betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis
-
Laporte, S. A., Oakley, R. H., Zhang, J., Holt, J. A., Ferguson, S. S., Caron, M. G., et al. (1999). The beta2-adrenergic receptor/ betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis. Proceedings of the National Academy of Sciences of the United States of America, 96, 3712-3717.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 3712-3717
-
-
Laporte, S.A.1
Oakley, R.H.2
Zhang, J.3
Holt, J.A.4
Ferguson, S.S.5
Caron, M.G.6
-
56
-
-
33644858084
-
The role of receptor internalization in CD95 signaling
-
Lee, K. H., Feig, C., Tchikov, V., Schickel, R., Hallas, C., Schutze, S., et al. (2006). The role of receptor internalization in CD95 signaling. The EMBO Journal, 25, 1009-1023.
-
(2006)
The EMBO Journal
, vol.25
, pp. 1009-1023
-
-
Lee, K.H.1
Feig, C.2
Tchikov, V.3
Schickel, R.4
Hallas, C.5
Schutze, S.6
-
57
-
-
69949185018
-
Silencing by small RNAs is linked to endosomal trafficking
-
Lee, Y. S., Pressman, S., Andress, A. P., Kim, K., White, J. L., Cassidy, J. J., et al. (2009). Silencing by small RNAs is linked to endosomal trafficking. Nature Cell Biology, 11, 1150-1156.
-
(2009)
Nature Cell Biology
, vol.11
, pp. 1150-1156
-
-
Lee, Y.S.1
Pressman, S.2
Andress, A.P.3
Kim, K.4
White, J.L.5
Cassidy, J.J.6
-
59
-
-
33947420477
-
Seven transmembrane receptors: A brief personal retrospective
-
Lefkowitz, R. J. (2007). Seven transmembrane receptors: A brief personal retrospective. Biochimica et Biophysica Acta, 1768, 748-755.
-
(2007)
Biochimica et Biophysica Acta
, vol.1768
, pp. 748-755
-
-
Lefkowitz, R.J.1
-
60
-
-
0031028273
-
Two EGF molecules contribute additively to stabilization of the EGFR dimer
-
Lemmon, M. A., Bu, Z., Ladbury, J. E., Zhou, M., Pinchasi, D., Lax, I., et al. (1997). Two EGF molecules contribute additively to stabilization of the EGFR dimer. The EMBO Journal, 16, 281-294.
-
(1997)
The EMBO Journal
, vol.16
, pp. 281-294
-
-
Lemmon, M.A.1
Bu, Z.2
Ladbury, J.E.3
Zhou, M.4
Pinchasi, D.5
Lax, I.6
-
61
-
-
49849094555
-
Reviews in molecular biology and biotechnology: Transmembrane signaling by G protein-coupled receptors
-
Luttrell, L. M. (2008). Reviews in molecular biology and biotechnology: Transmembrane signaling by G protein-coupled receptors. Molecular Biotechnology, 39, 239-264.
-
(2008)
Molecular Biotechnology
, vol.39
, pp. 239-264
-
-
Luttrell, L.M.1
-
62
-
-
0033613938
-
Betaarrestin-dependent formation of beta2 adrenergic receptorsrc protein kinase complexes
-
Luttrell, L. M., Ferguson, S. S., Daaka, Y., Miller, W. E., Maudsley, S., Della Rocca, G. J., et al. (1999). Betaarrestin-dependent formation of beta2 adrenergic receptorsrc protein kinase complexes. Science, 283, 655-661.
-
(1999)
Science
, vol.283
, pp. 655-661
-
-
Luttrell, L.M.1
Ferguson, S.S.2
Daaka, Y.3
Miller, W.E.4
Maudsley, S.5
Della Rocca, G.J.6
-
63
-
-
0035956983
-
Activation and targeting of extracellular signal-regulated kinases by betaarrestin scaffolds
-
Luttrell, L. M., Roudabush, F. L., Choy, E. W., Miller, W. E., Field, M. E., Pierce, K. L., et al. (2001). Activation and targeting of extracellular signal-regulated kinases by betaarrestin scaffolds. Proceedings of the National Academy of Sciences of the United States of America, 98, 2449-2454.
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
-
-
Luttrell, L.M.1
Roudabush, F.L.2
Choy, E.W.3
Miller, W.E.4
Field, M.E.5
Pierce, K.L.6
-
65
-
-
0035824563
-
Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting
-
Marchese, A., & Benovic, J. L. (2001). Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting. The Journal of Biological Chemistry, 276, 45509-45512.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 45509-45512
-
-
Marchese, A.1
Benovic, J.L.2
-
66
-
-
0038487327
-
The ins and outs of G protein-coupled receptor trafficking
-
Marchese, A., Chen, C., Kim, Y. M., & Benovic, J. L. (2003). The ins and outs of G protein-coupled receptor trafficking. Trends in Biochemical Sciences, 28, 369-376.
-
(2003)
Trends in Biochemical Sciences
, vol.28
, pp. 369-376
-
-
Marchese, A.1
Chen, C.2
Kim, Y.M.3
Benovic, J.L.4
-
67
-
-
33646562542
-
The logic of TGFbeta signaling
-
Massague, J., & Gomis, R. R. (2006). The logic of TGFbeta signaling. FEBS Letters, 580, 2811-2820.
-
(2006)
FEBS Letters
, vol.580
, pp. 2811-2820
-
-
Massague, J.1
Gomis, R.R.2
-
68
-
-
0034737483
-
The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
-
Maudsley, S., Pierce, K. L., Zamah, A. M., Miller, W. E., Ahn, S., Daaka, Y., et al. (2000). The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. The Journal of Biological Chemistry, 275, 9572-9580.
-
(2000)
The Journal of Biological Chemistry
, vol.275
, pp. 9572-9580
-
-
Maudsley, S.1
Pierce, K.L.2
Zamah, A.M.3
Miller, W.E.4
Ahn, S.5
Daaka, Y.6
-
69
-
-
0034711397
-
Beta-arrestin 2: A receptor-regulated MAPK scaffold for the activation of JNK3
-
Mcdonald, P. H., Chow, C. W., Miller, W. E., Laporte, S. A., Field, M. E., Lin, F. T., et al. (2000). Beta-arrestin 2: A receptor-regulated MAPK scaffold for the activation of JNK3. Science, 290, 1574-1577.
-
(2000)
Science
, vol.290
, pp. 1574-1577
-
-
Mcdonald, P.H.1
Chow, C.W.2
Miller, W.E.3
Laporte, S.A.4
Field, M.E.5
Lin, F.T.6
-
70
-
-
51649121376
-
Survival of the weakest: Signaling aided by endosomes
-
Mcshane, M. P., & Zerial, M. (2008). Survival of the weakest: Signaling aided by endosomes. The Journal of Cell Biology, 182, 823-825.
-
(2008)
The Journal of Cell Biology
, vol.182
, pp. 823-825
-
-
Mcshane, M.P.1
Zerial, M.2
-
71
-
-
1642417606
-
APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment
-
Miaczynska, M., Christoforidis, S., Giner, A., Shevchenko, A., Uttenweiler-Joseph, S., Habermann, B., et al. (2004a). APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell, 116, 445-456.
-
(2004)
Cell
, vol.116
, pp. 445-456
-
-
Miaczynska, M.1
Christoforidis, S.2
Giner, A.3
Shevchenko, A.4
Uttenweiler-Joseph, S.5
Habermann, B.6
-
72
-
-
3142592401
-
Not just a sink: Endosomes in control of signal transduction
-
Miaczynska, M., Pelkmans, L., & Zerial, M. (2004b). Not just a sink: Endosomes in control of signal transduction. Current Opinion Cell Biology, 16, 400-406.
-
(2004)
Current Opinion Cell Biology
, vol.16
, pp. 400-406
-
-
Miaczynska, M.1
Pelkmans, L.2
Zerial, M.3
-
73
-
-
18844411824
-
The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation
-
Milasta, S., Evans, N. A., Ormiston, L., Wilson, S., Lefkowitz, R. J., & Milligan, G. (2005). The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation. The Biochemical Journal, 387, 573-584.
-
(2005)
The Biochemical Journal
, vol.387
, pp. 573-584
-
-
Milasta, S.1
Evans, N.A.2
Ormiston, L.3
Wilson, S.4
Lefkowitz, R.J.5
Milligan, G.6
-
74
-
-
0035819080
-
On trk for retrograde signaling
-
Miller, F. D., & Kaplan, D. R. (2001). On trk for retrograde signaling. Neuron, 32, 767-770.
-
(2001)
Neuron
, vol.32
, pp. 767-770
-
-
Miller, F.D.1
Kaplan, D.R.2
-
75
-
-
27644438783
-
Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes
-
Mizuno, E., Iura, T.,Mukai,A., Yoshimori, T.,Kitamura, N., & Komada, M. (2005). Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes. Molecular Biology Cell, 16, 5163-5174.
-
(2005)
Molecular Biology Cell
, vol.16
, pp. 5163-5174
-
-
Mizuno, E.1
Iura, T.2
Mukai, A.3
Yoshimori, T.4
Kitamura, N.5
Komada, M.6
-
76
-
-
65949105042
-
Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors
-
Mullershausen, F., Zecri, F., Cetin, C., Billich, A., Guerini, D., & Seuwen, K. (2009). Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors. Nature Chemical Biology, 5, 428-434.
-
(2009)
Nature Chemical Biology
, vol.5
-
-
Mullershausen, F.1
Zecri, F.2
Cetin, C.3
Billich, A.4
Guerini, D.5
Seuwen, K.6
-
77
-
-
70449552889
-
Endosomes: A legitimate platform for the signaling train
-
Murphy, J. E., Padilla, B. E., Hasdemir, B., Cottrell, G. S., & Bunnett, N. W. (2009). Endosomes: A legitimate platform for the signaling train. Proceedings of the National Academy of Sciences of the United States of America, 106, 17615-17622.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 17615-17622
-
-
Murphy, J.E.1
Padilla, B.E.2
Hasdemir, B.3
Cottrell, G.S.4
Bunnett, N.W.5
-
78
-
-
0028084202
-
Vascular endothelial growth factor and its receptors
-
Neufeld, G., Tessler, S., Gitay-Goren, H., Cohen, T., & Levi, B. Z. (1994). Vascular endothelial growth factor and its receptors. Progress of Growth Factor Research, 5, 89-97.
-
(1994)
Progress of Growth Factor Research
, vol.5
-
-
Neufeld, G.1
Tessler, S.2
Gitay-Goren, H.3
Cohen, T.4
Levi, B.Z.5
-
79
-
-
0033527663
-
Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization
-
Oakley, R. H., Laporte, S. A., Holt, J. A., Barak, L. S., & Caron, M. G. (1999). Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. The Journal of Biological Chemistry, 274, 32248-32257.
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 32248-32257
-
-
Oakley, R.H.1
Laporte, S.A.2
Holt, J.A.3
Barak, L.S.4
Caron, M.G.5
-
80
-
-
0034595860
-
Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors
-
Oakley, R. H., Laporte, S. A., Holt, J. A., Caron, M. G., & Barak, L. S. (2000). Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors. The Journal of Biological Chemistry, 275, 17201-17210.
-
(2000)
The Journal of Biological Chemistry
, vol.275
, pp. 17201-17210
-
-
Oakley, R.H.1
Laporte, S.A.2
Holt, J.A.3
Caron, M.G.4
Barak, L.S.5
-
81
-
-
0036272313
-
Internalizationdependent and -independent requirements for transforming growth factor beta receptor signaling via the smad pathway
-
Penheiter, S. G., Mitchell, H., Garamszegi, N., Edens, M., Dore, J. J. Jr., & Leof, E. B. (2002). Internalizationdependent and -independent requirements for transforming growth factor beta receptor signaling via the smad pathway. Molecular and Cellular Biology, 22, 4750-4759.
-
(2002)
Molecular and Cellular Biology
, vol.22
, pp. 4750-4759
-
-
Penheiter, S.G.1
Mitchell, H.2
Garamszegi, N.3
Edens, M.4
Dore Jr., J.J.5
Leof, E.B.6
-
82
-
-
0035952645
-
New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades
-
Pierce, K. L., Luttrell, L. M., & Lefkowitz, R. J. (2001). New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades. Oncogene, 20, 1532-1539.
-
(2001)
Oncogene
, vol.20
, pp. 1532-1539
-
-
Pierce, K.L.1
Luttrell, L.M.2
Lefkowitz, R.J.3
-
83
-
-
29244452619
-
Growth factor receptors, lipid rafts and caveolae: An evolving story
-
Pike, L. J. (2005). Growth factor receptors, lipid rafts and caveolae: An evolving story. Biochimica et Biophysica Acta, 1746, 260-273.
-
(2005)
Biochimica et Biophysica Acta
, vol.1746
, pp. 260-273
-
-
Pike, L.J.1
-
84
-
-
0037869027
-
Regulation of insulin receptor kinase activity by endosomal processes: Possible areas for therapeutic intervention
-
Posner, B. I. (2003). Regulation of insulin receptor kinase activity by endosomal processes: Possible areas for therapeutic intervention. Current Opinion in Investigational Drugs, 4, 430-434.
-
(2003)
Current Opinion in Investigational Drugs
, vol.4
, pp. 430-434
-
-
Posner, B.I.1
-
85
-
-
0028136598
-
Peroxovanadium compounds
-
Posner, B. I., Faure, R., Burgess, J. W., Bevan, A. P., Lachance, D., Zhang-Sun, G., et al. (1994). Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics. Journal of Biological Chemistry, 269, 4596-4604.
-
(1994)
A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics. Journal of Biological Chemistry
, vol.269
, pp. 4596-4604
-
-
Posner, B.I.1
Faure, R.2
Burgess, J.W.3
Bevan, A.P.4
Lachance, D.5
Zhang-Sun, G.6
-
86
-
-
0018854499
-
Uptake of insulin by plasmalemma and Golgi subcellular fractions of rat liver
-
Posner, B. I., Patel, B., Verma, A. K., & Bergeron, J. J. (1980). Uptake of insulin by plasmalemma and Golgi subcellular fractions of rat liver. Journal of Biological Chemistry, 255, 735-741.
-
(1980)
Journal of Biological Chemistry
, vol.255
, pp. 735-741
-
-
Posner, B.I.1
Patel, B.2
Verma, A.K.3
Bergeron, J.J.4
-
87
-
-
67949106368
-
Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis
-
Pyrzynska, B., Pilecka, I., & Miaczynska, M. (2009). Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis. Molecular Oncology, 3, 321-338.
-
(2009)
Molecular Oncology
, vol.3
, pp. 321-338
-
-
Pyrzynska, B.1
Pilecka, I.2
Miaczynska, M.3
-
88
-
-
42549148456
-
Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting
-
Rajendran, L., Schneider, A., Schlechtingen, G., Weidlich, S., Ries, J., Braxmeier, T., et al. (2008). Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting. Science, 320, 520-523.
-
(2008)
Science
, vol.320
, pp. 520-523
-
-
Rajendran, L.1
Schneider, A.2
Schlechtingen, G.3
Weidlich, S.4
Ries, J.5
Braxmeier, T.6
-
89
-
-
67650540827
-
Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/ TCF-mediated transcription
-
Rashid, S., Pilecka, I., Torun, A., Olchowik, M., Bielinska, B., & Miaczynska, M. (2009). Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/ TCF-mediated transcription. The Journal of Biological Chemistry, 284, 18115-18128.
-
(2009)
The Journal of Biological Chemistry
, vol.284
, pp. 18115-18128
-
-
Rashid, S.1
Pilecka, I.2
Torun, A.3
Olchowik, M.4
Bielinska, B.5
Miaczynska, M.6
-
90
-
-
0030801304
-
An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons
-
Riccio, A., Pierchala, B. A., Ciarallo, C. L., & Ginty, D. D. (1997). An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons. Science, 277, 1097-1100.
-
(1997)
Science
, vol.277
, pp. 1097-1100
-
-
Riccio, A.1
Pierchala, B.A.2
Ciarallo, C.L.3
Ginty, D.D.4
-
91
-
-
0015828774
-
Peptide hormone binding to receptors: A review of direct studies in vitro
-
Roth, J. (1973). Peptide hormone binding to receptors: A review of direct studies in vitro. Metabolism, 22, 1059-1073.
-
(1973)
Metabolism
, vol.22
, pp. 1059-1073
-
-
Roth, J.1
-
92
-
-
35848943698
-
Mitogenic signaling pathways induced by G protein-coupled receptors
-
Rozengurt, E. (2007). Mitogenic signaling pathways induced by G protein-coupled receptors. Journal of Cellular Physiology, 213, 589-602.
-
(2007)
Journal of Cellular Physiology
, vol.213
, pp. 589-602
-
-
Rozengurt, E.1
-
93
-
-
42949092018
-
The endosomal protein APPL1 mediates akt substrate specificity and cell survival in vertebrate development
-
Schenck, A., Goto-Silva, L., Collinet, C., Rhinn, M., Giner, A., Habermann, B., et al. (2008). The endosomal protein APPL1 mediates akt substrate specificity and cell survival in vertebrate development. Cell, 133, 486-497.
-
(2008)
Cell
, vol.133
, pp. 486-497
-
-
Schenck, A.1
Goto-Silva, L.2
Collinet, C.3
Rhinn, M.4
Giner, A.5
Habermann, B.6
-
94
-
-
4444341939
-
Compartmentalization of TNF receptor 1 signaling: Internalized TNF receptosomes as death signaling vesicles
-
Schneider-Brachert, W., Tchikov, V., Neumeyer, J., Jakob, M., Winoto-Morbach, S., Held-Feindt, J., et al. (2004). Compartmentalization of TNF receptor 1 signaling: Internalized TNF receptosomes as death signaling vesicles. Immunity, 21, 415-428.
-
(2004)
Immunity
, vol.21
, pp. 415-428
-
-
Schneider-Brachert, W.1
Tchikov, V.2
Neumeyer, J.3
Jakob, M.4
Winoto-Morbach, S.5
Held-Feindt, J.6
-
95
-
-
47749089820
-
Regulation of TNFR1 and CD95 signalling by receptor compartmentalization
-
Schutze, S., Tchikov, V., & Schneider-Brachert, W. (2008). Regulation of TNFR1 and CD95 signalling by receptor compartmentalization. Nature Reviews Molecular Cell Biology, 9, 655-662.
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
-
-
Schutze, S.1
Tchikov, V.2
Schneider-Brachert, W.3
-
96
-
-
33646263875
-
Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins
-
Scott, M. G., Pierotti, V., Storez, H., Lindberg, E., Thuret, A., Muntaner, O., et al. (2006). Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins. Molecular and Cellular Biology, 26, 3432-3445.
-
(2006)
Molecular and Cellular Biology
, vol.26
-
-
Scott, M.G.1
Pierotti, V.2
Storez, H.3
Lindberg, E.4
Thuret, A.5
Muntaner, O.6
-
97
-
-
0346156094
-
GPCR-mediated transactivation of RTKs in the CNS: Mechanisms and consequences
-
Shah, B. H. & Catt, K. J. (2004). GPCR-mediated transactivation of RTKs in the CNS: Mechanisms and consequences. Trends Neuroscience, 27, 48-53.
-
(2004)
Trends Neuroscience
, vol.27
, pp. 48-53
-
-
Shah, B.H.1
Catt, K.J.2
-
98
-
-
34247573976
-
Seven-transmembrane receptors and ubiquitination
-
Shenoy, S. K. (2007). Seven-transmembrane receptors and ubiquitination. Circulation Research, 100, 1142-1154.
-
(2007)
Circulation Research
, vol.100
, pp. 1142-1154
-
-
Shenoy, S.K.1
-
99
-
-
0035834428
-
Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin
-
Shenoy, S. K., Mcdonald, P. H., Kohout, T. A., & Lefkowitz, R. J. (2001). Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science, 294, 1307-1313.
-
(2001)
Science
, vol.294
, pp. 1307-1313
-
-
Shenoy, S.K.1
Mcdonald, P.H.2
Kohout, T.A.3
Lefkowitz, R.J.4
-
100
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi, Y., & Massague, J. (2003). Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell, 113, 685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
101
-
-
33745685061
-
Activation of the phosphatidylinositol 3-kinase vps34 by a G protein alpha subunit at the endosome
-
Slessareva, J. E., Routt, S. M., Temple, B., Bankaitis, V. A., & Dohlman, H. G. (2006). Activation of the phosphatidylinositol 3-kinase vps34 by a G protein alpha subunit at the endosome. Cell, 126, 191-203.
-
(2006)
Cell
, vol.126
, pp. 191-203
-
-
Slessareva, J.E.1
Routt, S.M.2
Temple, B.3
Bankaitis, V.A.4
Dohlman, H.G.5
-
102
-
-
34547103996
-
Beta-arrestin-dependent parathyroid hormone-stimulated extracellular signalregulated kinase activation and parathyroid hormone type 1 receptor internalization
-
Sneddon, W. B., & Friedman, P. A. (2007). Beta-arrestin-dependent parathyroid hormone-stimulated extracellular signalregulated kinase activation and parathyroid hormone type 1 receptor internalization. Endocrinology, 148, 4073-4079.
-
(2007)
Endocrinology
, vol.148
, pp. 4073-4079
-
-
Sneddon, W.B.1
Friedman, P.A.2
-
103
-
-
0036341207
-
Signal transduction and endocytosis: Close encounters of many kinds
-
Sorkin, A., & Von Zastrow, M. (2002). Signal transduction and endocytosis: Close encounters of many kinds. Nature Reviews Molecular Cell Biology, 3, 600-614.
-
(2002)
Nature Reviews Molecular Cell Biology
, vol.3
, pp. 600-614
-
-
Sorkin, A.1
Von Zastrow, M.2
-
105
-
-
0242351936
-
The odd couple: Signal transduction and endocytosis
-
Teis, D., & Huber, L. A. (2003). The odd couple: Signal transduction and endocytosis. Cellular and Molecular Life Sciences, 60, 2020-2033.
-
(2003)
Cellular and Molecular Life Sciences
, vol.60
, pp. 2020-2033
-
-
Teis, D.1
Huber, L.A.2
-
106
-
-
0036899420
-
Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction
-
Teis, D., Wunderlich, W., & Huber, L. A. (2002). Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction. Developmental Cell, 3, 803-814.
-
(2002)
Developmental Cell
, vol.3
, pp. 803-814
-
-
Teis, D.1
Wunderlich, W.2
Huber, L.A.3
-
107
-
-
8144222927
-
Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes
-
Terrillon, S., & Bouvier, M. (2004). Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes. The EMBO Journal, 23, 3950-3961.
-
(2004)
The EMBO Journal
, vol.23
, pp. 3950-3961
-
-
Terrillon, S.1
Bouvier, M.2
-
108
-
-
64749097246
-
A notch updated
-
Tien, A. C., Rajan, A., & Bellen, H. J. (2009). A notch updated. The Journal of Cell Biology, 184, 621-629.
-
(2009)
The Journal of Cell Biology
, vol.184
, pp. 621-629
-
-
Tien, A.C.1
Rajan, A.2
Bellen, H.J.3
-
109
-
-
0037458614
-
The stability of the G proteincoupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation
-
Tohgo, A., Choy, E. W., Gesty-Palmer, D., Pierce, K. L., Laporte, S., Oakley, R. H., et al. (2003). The stability of the G proteincoupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. The Journal of Biological Chemistry, 278, 6258-6267.
-
(2003)
The Journal of Biological Chemistry
, vol.278
, pp. 6258-6267
-
-
Tohgo, A.1
Choy, E.W.2
Gesty-Palmer, D.3
Pierce, K.L.4
Laporte, S.5
Oakley, R.H.6
-
110
-
-
0028568644
-
Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2
-
Tsuga, H., Kameyama, K., Haga, T., Kurose, H., & Nagao, T. (1994). Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2. The Journal of Biological Chemistry, 269, 32522-32527.
-
(1994)
The Journal of Biological Chemistry
, vol.269
, pp. 32522-32527
-
-
Tsuga, H.1
Kameyama, K.2
Haga, T.3
Kurose, H.4
Nagao, T.5
-
111
-
-
40849114907
-
Endosomal entry regulates notch receptor activation in Drosophila melanogaster
-
Vaccari, T., Lu, H., Kanwar, R., Fortini, M. E., & Bilder, D. (2008). Endosomal entry regulates notch receptor activation in Drosophila melanogaster. The Journal of Cell Biology, 180, 755-762.
-
(2008)
The Journal of Cell Biology
, vol.180
, pp. 755-762
-
-
Vaccari, T.1
Lu, H.2
Kanwar, R.3
Fortini, M.E.4
Bilder, D.5
-
112
-
-
0030461226
-
Control of EGF receptor signaling by clathrin-mediated endocytosis
-
Vieira, A. V., Lamaze, C., & Schmid, S. L. (1996). Control of EGF receptor signaling by clathrin-mediated endocytosis. Science, 274, 2086-2089.
-
(1996)
Science
, vol.274
, pp. 2086-2089
-
-
Vieira, A.V.1
Lamaze, C.2
Schmid, S.L.3
-
113
-
-
66449111715
-
Beta-arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice
-
Walters, R. W., Shukla, A. K., Kovacs, J. J., Violin, J. D., Dewire, S. M., Lam, C. M., et al. (2009). Beta-arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice. The Journal of Clinical Investigation, 119, 1312-1321.
-
(2009)
The Journal of Clinical Investigation
, vol.119
, pp. 1312-1321
-
-
Walters, R.W.1
Shukla, A.K.2
Kovacs, J.J.3
Violin, J.D.4
Dewire, S.M.5
Lam, C.M.6
-
114
-
-
0036787904
-
Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival
-
Wang, Y., Pennock, S., Chen, X., & Wang, Z. (2002). Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival. Molecular and Cellular Biology, 22, 7279-7290.
-
(2002)
Molecular and Cellular Biology
, vol.22
, pp. 7279-7290
-
-
Wang, Y.1
Pennock, S.2
Chen, X.3
Wang, Z.4
-
115
-
-
66149171646
-
Compartmentalization of epidermal growth factor receptor in liver plasma membrane
-
Wang, Y., Posner, B. I., & Balbis, A. (2009). Compartmentalization of epidermal growth factor receptor in liver plasma membrane. Journal of Cellular Biochemistry, 107, 96-103.
-
(2009)
Journal of Cellular Biochemistry
, vol.107
, pp. 96-103
-
-
Wang, Y.1
Posner, B.I.2
Balbis, A.3
-
116
-
-
0034804675
-
Neurotrophins use the Erk5 pathway to mediate a retrograde survival response
-
Watson, F. L., Heerssen, H. M., Bhattacharyya, A., Klesse, L., Lin, M. Z., & Segal, R. A. (2001). Neurotrophins use the Erk5 pathway to mediate a retrograde survival response. Nature Neuroscience, 4, 981-988.
-
(2001)
Nature Neuroscience
, vol.4
, pp. 981-988
-
-
Watson, F.L.1
Heerssen, H.M.2
Bhattacharyya, A.3
Klesse, L.4
Lin, M.Z.5
Segal, R.A.6
-
117
-
-
0033568881
-
Rapid nuclear responses to target-derived neurotrophins require retrograde transport of ligand-receptor complex
-
Watson, F. L., Heerssen, H. M., Moheban, D. B., Lin, M. Z., Sauvageot, C. M., Bhattacharyya, A., et al. (1999). Rapid nuclear responses to target-derived neurotrophins require retrograde transport of ligand-receptor complex. Journal of Neuroscience, 19, 7889-7900.
-
(1999)
Journal of Neuroscience
, vol.19
, pp. 7889-7900
-
-
Watson, F.L.1
Heerssen, H.M.2
Moheban, D.B.3
Lin, M.Z.4
Sauvageot, C.M.5
Bhattacharyya, A.6
-
118
-
-
0025139326
-
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor
-
Wells, A., Welsh, J. B., Lazar, C. S., Wiley, H. S., Gill, G. N., & Rosenfeld, M. G. (1990). Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science, 247, 962-964.
-
(1990)
Science
, vol.247
, pp. 962-964
-
-
Wells, A.1
Welsh, J.B.2
Lazar, C.S.3
Wiley, H.S.4
Gill, G.N.5
Rosenfeld, M.G.6
-
119
-
-
0043172403
-
Transactivation joins multiple tracks to the ERK/MAPK cascade
-
Wetzker, R., & Bohmer, F. D. (2003). Transactivation joins multiple tracks to the ERK/MAPK cascade. Nature Reviews Molecular Cell Biology, 4, 651-657.
-
(2003)
Nature Reviews Molecular Cell Biology
, vol.4
, pp. 651-657
-
-
Wetzker, R.1
Bohmer, F.D.2
-
120
-
-
60649118104
-
The coming of age of axonal neurotrophin signaling endosomes
-
Wu, C., Cui, B., He, L., Chen, L., & Mobley, W. C. (2009). The coming of age of axonal neurotrophin signaling endosomes. Journal of Proteomics, 72, 46-55.
-
(2009)
Journal of Proteomics
, vol.72
, pp. 46-55
-
-
Wu, C.1
Cui, B.2
He, L.3
Chen, L.4
Mobley, W.C.5
-
121
-
-
0035426219
-
Nerve growth factor activates persistent Rap1 signaling in endosomes
-
Wu, C., Lai, C. F., & Mobley, W. C. (2001). Nerve growth factor activates persistent Rap1 signaling in endosomes. Journal of Neuroscience, 21, 5406-5416.
-
(2001)
Journal of Neuroscience
, vol.21
, pp. 5406-5416
-
-
Wu, C.1
Lai, C.F.2
Mobley, W.C.3
-
122
-
-
69949137273
-
The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila
-
Yan, Y., Denef, N., & Schupbach, T. (2009). The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila. Developmental Cell, 17, 387-402.
-
(2009)
Developmental Cell
, vol.17
, pp. 387-402
-
-
Yan, Y.1
Denef, N.2
Schupbach, T.3
-
123
-
-
0042347474
-
Three-dimensional structural interactions of insulin and its receptor
-
Yip, C. C., & Ottensmeyer, P. (2003). Three-dimensional structural interactions of insulin and its receptor. The Journal of Biological Chemistry, 278, 27329-27332.
-
(2003)
The Journal of Biological Chemistry
, vol.278
, pp. 27329-27332
-
-
Yip, C.C.1
Ottensmeyer, P.2
-
124
-
-
57049140415
-
c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway
-
Zimmerman, B., Simaan, M., Lee, M. H., Luttrell, L. M., & Laporte, S. A. (2009). c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway. Cellular Signalling, 21, 103-110.
-
(2009)
Cellular Signalling
, vol.21
, pp. 103-110
-
-
Zimmerman, B.1
Simaan, M.2
Lee, M.H.3
Luttrell, L.M.4
Laporte, S.A.5
|