Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival

Molecular and Cellular Biology

Volumn 22, Issue 20, 2002, Pages 7279-7290

  Wang, Yi ^a   Pennock, Steven ^a   Chen, Xinmei ^a   Wang, Zhixiang ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MONENSIN; RAS PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FRACTIONATION; CELL MEMBRANE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; INTERNALIZATION; NONHUMAN; OUTCOMES RESEARCH; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELL SURVIVAL; DOGS; ENDOSOMES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0036787904     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.20.7279-7290.2002     Document Type: Article

References (44)

1. Ahn, S., S. Maudsley, L. M. Luttrell, R. J. Lefkowitz, and Y. Daaka. 1999. Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. J. Biol. Chem. 274:1185-1188.
2. Barbieri, M. A., R. L. Roberts, A. Gumusboga, H. Highfield, C. Alvarez-Dominguez, A. Wells, and P. D. Stahl. 2000. Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a. J. Cell Biol. 151:539-550.
3. Burgering, B. M., and P. J. Coffer. 1995. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602.
4. Burke, P., K. Schooler, and H. S. Wiley. 2001. Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking. Mol. Biol. Cell 12:1897-1910.
5. Carpenter, G. 1987. Receptors for epidermal growth factor and other polypeptide mitogens. Annu. Rev. Biochem. 56:881-914.
6. Ceresa, B. P., A. W. Kao, S. R. Santeler, and J. E. Pessin. 1998. Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways. Mol. Cell. Biol. 18:3862-3870.
7. Ceresa, B. P., and S. L. Schmid. 2000. Regulation of signal transduction by endocytosis. Curr. Opin. Cell Biol. 12:204-210.
8. Chen, W. S., C. S. Lazar, K. A. Lund, J. B. Welsh, C. P. Chang, G. M. Walton, C. J. Der, H. S. Wiley, G. N. Gill, and M. G. Rosenfeld. 1989. Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell 59:33-43.
9. Chen, X., and Z. Wang. 2001. Regulation of intracellular trafficking of the EGF receptor by Rab5 in the absence of phosphatidylinositol 3-kinase activity. EMBO Rep. 2:68-74.
10. Clague, M. J., and S. Urbe. 2001. The interface of receptor trafficking and signalling. J. Cell Sci. 114:3075-3081.
11. Cohen, S., and R. A. Fava. 1985. Internalization of functional epidermal growth factor: receptor/kinase complexes in A-431 cells. J. Biol. Chem. 260:12351-12358.
12. Di Fiore, P. P., and P. De Camilli. 2001. Endocytosis and signaling: an inseparable partnership. Cell 106:1-4.
13. Di Fiore, P. P., and G. N. Gill. 1999. Endocytosis and mitogenic signaling. Curr. Opin. Cell Biol. 11:483-488.
14. Di Guglielmo, G. M., P. C. Baass, W. J. Ou, B. I. Posner, and J. J. Bergeron. 1994. Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma. EMBO J. 13:4269-4277.
15. Downward, J. 1998. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10:262-267.
16. Felder, S., K. Miller, G. Moehren, A. Ullrich, J. Schlessinger, and C. R. Hopkins. 1990. Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body. Cell 61:623-634.
17. Fukazawa, T., S. Miyake, V. Band, and H. Band. 1996. Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins. J. Biol. Chem. 271:14554-14559.
18. Glenney, J. R., Jr., W. S. Chen, C. S. Lazar, G. M. Walton, L. M. Zokas, M. G. Rosenfeld, and G. N. Gill. 1988. Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies. Cell 52:675-684.
19. Haugh, J. M., A. C. Huang, H. S. Wiley, A. Wells, and D. A. Lauffenburger. 1999. Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts. J. Biol. Chem. 274:34350-34360.
20. Herrmann, C., G. A. Martin, and A. Wittinghofer. 1995. Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase. J. Biol. Chem. 270:2901-2905.
21. Kay, D. G., W. H. Lai, M. Uchihashi, M. N. Khan, B. I. Posner, and J. J. Bergeron. 1986. Epidermal growth factor receptor kinase translocation and activation in vivo. J. Biol. Chem. 261:8473-8480.
22. Kuruvilla, R., H. Ye, and D. D. Ginty. 2000. Spatially and functionally distinct roles of the PI3-K effector pathway during NGF signaling in sympathetic neurons. Neuron 27:499-512.
23. Lai, W. H., P. H. Cameron, J. J. Doherty II, B. I. Posner, and J. J. Bergeron. 1989. Ligand-mediated autophosphorylation activity of the epidermal growth factor receptor during internalization. J. Cell Biol. 109:2751-2760.
24. Lanzetti, L., V. Rybin, M. G. Malabarba, S. Christoforidis, G. Scita, M. Zerial, and P. P. Di Fiore. 2000. The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5. Nature 408:374-377.
25. Levkowitz, G., H. Waterman, E. Zamir, Z. Kam, S. Oved, W. Y. Langdon, L. Beguinot, B. Geiger, and Y. Yarden. 1998. c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. Genes Dev. 12:3663-3674.
26. MacInnis, B. L., and R. B. Campenot. 2002. Retrograde support of neuronal survival without retrograde transport of nerve growth factor. Science 295: 1536-1539.
27. Marshall, C. J. 1994. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr. Opin. Genet. Dev. 4:82-89.
28. Marshall, C. J. 1996. Cell signalling. Raf gets it together. Nature 383:127-128.
29. Maudsley, S., K. L. Pierce, A. M. Zamah, W. E. Miller, S. Ahn, Y. Daaka, R. J. Lefkowitz, and L. M. Luttrell. 2000. The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. J. Biol. Chem. 275:9572-9580.
30. McPherson, P. S., B. K. Kay, and N. K. Hussain. 2001. Signaling on the endocytic pathway. Traffic 2:375-384.
31. Miller, W. E., and R. J. Lefkowitz. 2001. Expanding roles for beta-arrestins as scaffolds and adapters in GPCR signaling and trafficking. Curr. Opin. Cell Biol. 13:139-145.
32. Pawson, T. 1995. Protein modules and signalling networks. Nature 373:573-580.
33. Pawson, T. 1997. New impressions of Src and Hck. Nature 385:582-585.
34. Schlessinger, J. 1986. Allosteric regulation of the epidermal growth factor receptor kinase. J. Cell Biol. 103:2067-2072.
35. Schlessinger, J., and A. Ullrich. 1992. Growth factor signaling by receptor tyrosine kinases. Neuron 9:383-391.
36. Shen, Y., L. Xu, and D. A. Foster. 2001. Role for phospholipase D in receptor-mediated endocytosis. Mol. Cell. Biol. 21:595-602.
37. Slepnev, V. I., and P. De Camilli. 2000. Accessory factors in clathrin-dependent synaptic vesicle endocytosis. Nat. Rev. Neurosci. 1:161-172.
38. Sorkin, A., and G. Carpenter. 1993. Interaction of activated EGF receptors with coated pit adaptins. Science 261:612-615.
39. Vieira, A. V., C. Lamaze, and S. L. Schmid. 1996. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274:2086-2089.
40. Wang, Z., P. S. Tung, and M. F. Moran. 1996. Association of p120 ras GAP with endocytic components and colocalization with epidermal growth factor (EGF) receptor in response to EGF stimulation. Cell Growth Differ. 7:123-133.
41. Wang, Z., L. Zhang, T. K. Yeung, and X. Chen. 1999. Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation. Mol. Biol. Cell 10:1621-1636.
42. Waterman, H., I. Alroy, S. Strano, R. Seger, and Y. Yarden. 1999. The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing. EMBO J. 18:3348-3358.
43. Wiley, H. S., and P. M. Burke. 2001. Regulation of receptor tyrosine kinase signaling by endocytic trafficking. Traffic 2:12-18.
44. Yarden, Y., and M. X. Sliwkowski. 2001. Untangling the ErbB signalling network. Nat. Rev. Mol. Cell Biol. 2:127-137.