Molecular mechanism of the impairment in activation signal transduction in CD4+ T cells from old mice

International Immunology

Volumn 12, Issue 8, 2000, Pages 1205-1215

  Tamura, Toshiki ^a   Kunimatsu, Takeshi ^f   Yee, Sung Tae ^g   Igarashi, Osamu ^a   Utsuyama, Masanori ^b,c   Tanaka, Shin ^d   Miyazaki, Shun Ichi ^e   Hirokawa, Katsuiku ^d   Nariuchi, Hideo ^c  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^e TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^f SUMITOMO CHEMICAL CO LTD   (Japan)

^g Sunchon National University   (South Korea)

Author keywords

Protein kinase; Signal transduction; T lymphocytes; TCR

Indexed keywords

CALCIUM; CD3 ANTIGEN; CD4 ANTIGEN; FC RECEPTOR; INOSITOL PHOSPHATE; INTERLEUKIN 2; LYMPHOCYTE ANTIBODY; OKT 3; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR;

AGED; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL AGING; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; LYMPHOCYTE CLONE; MOUSE; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROTEIN METABOLISM; SENESCENCE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TH1 CELL;

EID: 0033865177     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/12.8.1205     Document Type: Article

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