Concentration of rafts in platelet filopodia correlates with recruitment of c-Src and CD63 to these domains

Journal of Thrombosis and Haemostasis

Volumn 1, Issue 6, 2003, Pages 1161-1173

  Heijnen, H F G ^a,c   Van Lier, M ^a,c   Waaijenborg, S ^a   Ohno Iwashita, Y ^b   Waheed, A A ^b   Inomata, M ^b   Gorter, G ^a   Mobius W ^a   Akkerman, J W N ^a,c   Slot, J W ^a,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c Institute for Biomembranes   (Netherlands)

Author keywords

Cholesterol; Platelets; Raft; Signaling

Indexed keywords

BETA CYCLODEXTRIN; BETA CYCLODEXTRIN DERIVATIVE; CHOLESTEROL; CSK PROTEIN, HUMAN; CYCLODEXTRIN; FIBRINOGEN; FIBRINOGEN RECEPTOR; LEUKOCYTE ANTIGEN; LYSOSOMAL PROTEIN GP53; ONCOPROTEIN; PHOSPHOTRANSFERASE; PROTEIN TYROSINE KINASE; THROMBIN RECEPTOR;

ARTICLE; CELL MEMBRANE; CELL SIZE; CHEMISTRY; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT; PSEUDOPODIUM; THROMBOCYTE; THROMBOCYTE ACTIVATION; ULTRASTRUCTURE;

ANTIGENS, CD; BETA-CYCLODEXTRINS; BLOOD PLATELETS; CELL SIZE; CHOLESTEROL; CYCLODEXTRINS; FIBRINOGEN; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE MICRODOMAINS; PHOSPHORYLATION; PHOSPHOTRANSFERASES; PLATELET ACTIVATION; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN TRANSPORT; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PSEUDOPODIA; RECEPTORS, THROMBIN;

EID: 1942501973     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1046/j.1538-7836.2003.00316.x     Document Type: Article

References (46)

1. Fox JEB. The platelet cytoskeleton. Thromb Hemost 1993; 70: 260-4.
2. Hartwig JH. Mechanisms of actin rearrangements mediating platelet activation. J Cell Biol 1992; 118: 1421-42.
3. Simons K, van Meer G. Lipid sorting in epithelial cells. Biochemistry 1988; 27: 6197-202.
4. Lisanti MP, Rodriguez-Boulan E. Glycophospholipid membrane anchoring provides clues to the mechanism of protein sorting in polarized epithelial cells. Trends Biochem Sci 1990; 15: 113-8.
5. Brown DA, Rose JK. Sorting of GPI-anchored proteins to glycolipidenriched membrane subdomains during transport to the apical cell surface. Cell 1992; 68: 533-44.
6. Xavier R, Brennan T, Li Q, McCormack C, Seed B. Membrane compartmentation is required for efficient T cell activation. Immunity 1998; 6: 723-32.
7. Ilangumaran S, Arni S, van Echten-Deckert G, Borisch B, Hoessli DC. Microdomain-dependent regulation of Lck and Fyn protein-tyrosine kinases in T lymphocyte plasma membranes. Mol Biol Cell 1999; 4: 891-905.
8. Manes S, Mira E, Gomez-Mouton C, Lacalle RA, Keller P, Labrador JP, Martinez AC. Membrane raft microdomains mediate front-rear polarity in migrating cells. EMBO J 1999; 18: 6211-20.
9. Fujimoto T. GPI-anchored proteins, glycosphingolipids, and sphingomyelin are sequestered to caveolae only after crosslinking. J Histochem Cytochem 1996; 44: 929-41.
10. Hagiwara H, Kogure SY, Nakamura M, Shimada Y, Ohno-Iwashita Y, Fujimoto T. Cross-linking of plasmalemmal cholesterol in lymphocytes induces capping, membrane shedding, and endocytosis through coated pits. Biochem Biophys Res Commun 1999; 260: 516-21.
11. Brown DA, London E. Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 1998; 14: 111-36.
12. Dorahy DJ, Lincz LF, Meldrum CJ, Burns GF. Biochemical isolation of a membrane microdomain from resting platelets highly enriched in the plasma membrane glycoprotein CD36. Biochem J 1996; 319: 67-72.
13. Dorahy DJ, Burns GF. Active Lyn protein tyrosine kinase is selectively enriched within membrane microdomains of resting platelets. Biochem J 1998; 333: 373-9.
14. Waheed AA, Shimada Y, Heijnen HFG, Nakamura M, Inomata M, Hayashi M, Iwashita S, Slot JW, Ohno-Iwashita Y. Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts). Proc Natl Acad Sci USA 2001; 98: 4926-31.
15. Fielding CJ, Fielding PE. Cholesterol and caveolae: structural and functional relationships. Biochim Biophys Acta 2000; 1529: 210-22.
16. Ikonen E, Parton RG. Caveolins and cellular cholesterol balance. Traffic 2000; 1: 212-7.
17. Shattil SJ, Anaya-Galindo R, Bennett J, Colman RW, Cooper RA. Platelet hypersensitivity induced by cholesterol incorporation. J Clin Invest 1975; 55: 636-43.
18. Cooper RA, Shattil SJ. Membrane cholesterol-is enough too much? N Engl J Med 1980; 302: 49-51.
19. Ohno-Iwshita Y, Iwamoto M, Mitsui K, Ando S. Cold-labile hemolysin produced by limited proteolysis of Y-toxin from Clostridium perfringens. Biochemistry 1986; 25: 6048-53.
20. Iwamoto M, Morita I, Fukuda M, Murota S, Ando S, Ohno-Iwashita Y. A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol. Biochim Biophys Acta 1997; 1327: 222-30.
21. Van Scharrenburg GJ, Puijk WC, Egmond MR, de Haas GH, Slotboom AJ. Semisynthesis of phospholipase A2. Preparation and properties of arginine-6 bovine pancreatic phopholipase A2. Biochemistry 1981; 20: 1584-91.
22. Beumer S, Heijnen HFG, IJsseldijk MJ, Orlando E, de Groot PG, Sixma JJ. Platelet adhesion to fibronectin in flow: the importance of von Willebrand factor and glycoprotein Ib. Blood 1995; 86: 3452-60.
23. Heijnen HFG, Lozano Molero M, de Groot PG, Nieuwenhuis HK, Sixma JJ. Absence of ligands, bound to GPIIb-IIIa on the exposed surface of a thrombus may limit thrombus growth in flowing blood. J Clin Invest 1994; 94: 1098-112.
24. Slot JW, Geuze HJ, Gigengack S, Lienhard GE, James DE. Immunolocalization of the insulin regulatable glucose transporter in brown adipose tissue of the rat. J Cell Biol 1991; 113: 123-35.
25. Möbius W, Ohno-Iwashita Y, van Donselaar E, Oorschot V, Shimida Y, Fujimoto T, Heijnen HFG, Geuze HJ, Slot JW. Immuno electron microscopic localization of cholesterol using biotinylated and noncytolytic perfringolysin O. J Histochem Cytochem 2002; 50: 43-56.
26. Stenberg PE, Pestina TI, Barrie RJ, JacksonCW. The Src family kinases, Fgr, Fyn, Lck, and Lyn, colocalize with coated membranes in platelets. Blood 1997; 89: 2384-93.
27. Heijnen HF, Debili N, Vainchencker W, Breton-Gorius J, Geuze HJ, Sixma JJ. Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules. Blood 1998; 91: 2313-25.
28. Ilangumaran S, Hoessli DC. Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane. Biochem J 1998; 335: 433-40.
29. Klein U, Gimpl G, Fahrenholz F. Alteration of the myometrial plasma membrane cholesterol contentwith beta-cyclodextrinmodulates the binding affinity of the oxytocin receptor. Biochemistry 1995; 34: 3784-93.
30. Fujimoto T, Hayashi M, Iwamoto M, Ohno-Iwashita Y. Cross-linked plasmalemmal cholesterol is sequestered to caveolae: analysis with a new cytochemical probe. J Histochem Cytochem 1997; 45: 1197-205.
31. Gousset K, Wolkers WF, Tsvetkoval NM, Oliver AE, Field CL, Walker NJ, Crowe JH, Tablin F. Evidence for a physiological role for membrane rafts in human platelets. J Cell Physiol 2002; 190: 17-28.
32. Kieffer N, Guichard J, Breton-Gorius J. Dynamic redistribution of major platelet surface receptors after contact-induced platelet activation and spreading. An immuno electronmicroscopy study. Am J Pathol 1992; 140: 57-73.
33. Mairhofer M, Steiner M, MosgoellerW, Prohaska R, Salzer U. Stomatin is a major lipid-raft component of platelet alpha granules. Blood 2002; 100: 897-904.
34. Ogata S, Fukuda M. Lysosomal targeting of Limp II membrane glycoprotein requires a novel Leu-Ile motif at a particular position in its cytoplasmic tail. J Biol Chem 1994; 269: 5210-7.
35. Ezumi Y, Kodama K, Uchiyama T, Takayama H. Constitutive and functional association of the platelet collagen receptor glycoprotein VI-Fc receptor-chain complex with membrane rafts. Blood 2002; 99: 3250-5.
36. Locke D, Chen H, Liu Y, Liu C, Kahn ML. Lipid rafts orchestrate signaling by the platelet receptor glycoprotein VI. J Biol Chem 2002; 277: 18801-9.
37. Obergfell A, Eto K, Mocsai A, Buensuceso C, Moores SL, Brugge JS, Lowell CA, Shattil SJ. Coordinate interactions of Csk Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton. J Cell Biol 2002; 157: 265-75.
38. Indig FE, Diaz-Gonzalez F, Ginsberg MH. Analysis of the tetraspanin CD9-integrin alphaIIbbeta3 (GPIIb-IIIa) complex in platelet membranes and transfected cells. Biochem J 1997; 327: 291-8.
39. Israels SJ, McMillan-Ward EM, Easton J, Robertson C, McNicol A. CD63 associates with the alphaIIb beta3 integrin-CD9 complex on the surface of activated platelets. Thromb Haemost 2001; 85: 134-41.
40. Miao WM, Vasile E, Lane WS, Lawler J. CD36 associates with CD9 and integrins on human blood platelets. Blood 2001; 97: 1689-96.
41. Claas C, Stipp CS, Hemler ME. Evaluation of prototype transmembrane 4 superfamily protein complexes and their relation to lipid rafts. J Biol Chem 2001; 276: 7974-84.
42. Wonerow P, Obergfell A,Wilde JI, Bobe R, Asazuma N, Brdicka T, Leo A, Schraven B, Horejsi V, Shattil SJ, Watson SP. Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase C-gamma 2 regulation in platelets. Biochem J 2002; 364: 755-65.
43. Shrimpton CN, Borthakur G, Larrucea S, Cruz MA, Dong JF, Lopez JA. Localization of the adhesion receptor Glycoprotein Ib-IX-V complex to lipid rafts is required for platelet adhesion and activation. J Exp Med 2002; 196: 1057-66.
44. Baglia FA, Shrimpton CN, López JA, Walsh PN. The Glycoprotein IbIXV complex mediates localization of Factor XI to lipid rafts on the platelet membrane. J Biol Chem 2003; 6 Jan [epub ahead of print].
45. Bodin S, Giuriato S, Ragab J, Humbel BM, Viala C, Vieu C, Chap H, Payrastre B. Production of phosphatidylinositol 3,4,5-trisphosphate and phosphatidic acid in platelet rafts: evidence for a critical role of cholesterol-enriched domains in human platelet activation. Biochemistry 2001; 18: 15290-9.
46. Berditchekova F, Tolias KF, Wong K, Carpenter CL, Hemler ME. A novel link between integrins, TM4SF proteins (CD63, CD81) and phosphatidylinositol 4-kinase. J Biol Chem 1997; 272: 2595-8.