Evidence linking genetics, environment, and epigenetics to impaired DNA repair in Alzheimer's disease

Journal of Alzheimer's Disease

Volumn 20, Issue 4, 2010, Pages 953-966

  Coppedè, Fabio ^a   Migliore, Lucia ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Alzheimer's disease; base excision repair; DNA damage; DNA repair; epigenetics; mild cognitive impairment; oxidative DNA damage

Indexed keywords

8 HYDROXYGUANINE; DEOXYRIBONUCLEASE; DEOXYRIBONUCLEASE I; DNA DIRECTED DNA POLYMERASE BETA; DNA GLYCOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NUCLEIC ACID; NUCLEOSIDE TRIPHOSPHATASE; URACIL DNA GLYCOSIDASE; XRCC1 PROTEIN;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; DISEASE ASSOCIATION; DNA DAMAGE; DNA POLYMORPHISM; DNA PROTEIN COMPLEX; DNA REPAIR; EPIGENETICS; EXCISION REPAIR; GENE DELETION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; MILD COGNITIVE IMPAIRMENT; NERVE CELL NECROSIS; NEUROPROTECTION; OXIDATION; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; COGNITIVE DEFECT; DOUBLE STRANDED DNA BREAK; ENVIRONMENT; GENETIC EPIGENESIS; GENETICS; META ANALYSIS; MUTATION; NERVE DEGENERATION; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; COGNITION DISORDERS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; ENVIRONMENT; EPIGENESIS, GENETIC; HUMANS; MUTATION; NERVE DEGENERATION; OXIDATIVE STRESS; POLYMORPHISM, GENETIC; SIGNAL TRANSDUCTION;

EID: 77954552201     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-1415     Document Type: Review

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