Neuronal DNA damage precedes tangle formation and is associated with up- regulation of nitrotyrosine in Alzheimer's disease brain

Brain Research

Volumn 774, Issue 1-2, 1997, Pages 193-199

  Su, Joseph H ^a   Deng, Gangmin ^a   Cotman, Carl W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; Neurofibrillary tangle; Neuronal DNA damage; Neuropathology; Nitrotyrosine; Oxidative injury

Indexed keywords

3 NITROTYROSINE; CELL DNA; DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; MONOCLONAL ANTIBODY; PEROXYNITRITE; TAU PROTEIN; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEMENTIA; DNA DAMAGE; DNA STRAND BREAKAGE; HUMAN; HUMAN TISSUE; NEUROFIBRILLARY TANGLE; PRIORITY JOURNAL; VISUAL CORTEX;

EID: 0031558654     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)81703-9     Document Type: Article

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