8,9-Epoxyeicosatrienoic acid analog protects pulmonary artery smooth muscle cells from apoptosis via ROCK pathway

Experimental Cell Research

Volumn 316, Issue 14, 2010, Pages 2340-2353

  Ma, Jun ^a   Zhang, Lei ^a   Li, Shanshan ^a   Liu, Shulin ^a,b   Ma, Cui ^a   Li, Weiyang ^c   Falck, J R ^d   Manthati, Vijay L ^d   Reddy, D Sudarshan ^d   Medhora, Meetha ^e   Jacobs, Elizabeth R ^e   Zhu, Daling ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Bio pharmaceutical Key Laboratory of Heilongjiang Province   (China)

^c MUDANJIANG MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

8,9 EET; 8,9 EET analog; Apoptosis; PASMCs; Rho kinase

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 8,9 EPOXY EICOS 11 ENOIC ACID; 8,9 EPOXYICOSATRIENOIC ACID; CASPASE 3; CASPASE 9; EPOXYICOSATRIENOIC ACID; FASUDIL; PROTEIN BAX; PROTEIN BCL 2; RHO KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTERY MUSCLE; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION REGULATION; LUNG ENDOTHELIUM; MALE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; RAT; SIGNAL TRANSDUCTION;

EID: 77954386544     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2010.05.013     Document Type: Article

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