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Volumn 82, Issue 1-4, 2007, Pages 19-29

Emerging mechanisms for growth and protection of the vasculature by cytochrome P450-derived products of arachidonic acid and other eicosanoids

Author keywords

Apoptosis; Cardioprotection; COX inhibitors; DDMS; HET0016

Indexed keywords

20 HYDROXYICOSATETRAENOIC ACID; ARACHIDONIC ACID; CASPASE 3; CELECOXIB; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; EPOXYICOSATRIENOIC ACID; ESSENTIAL FATTY ACID; GROWTH FACTOR; HET 0016; ICOSANOID; INDOMETACIN; LIPOXYGENASE; N HYDROXY N (4 BUTYL 2 METHYLPHENOL)FORMAMIDINE; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR;

EID: 33845313333     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2006.05.025     Document Type: Review
Times cited : (44)

References (65)
  • 1
    • 1842503012 scopus 로고    scopus 로고
    • Eicosanoid regulation of angiogenesis in tumors
    • Nie D., and Honn K.V. Eicosanoid regulation of angiogenesis in tumors. Semin Thromb Hemost 30 (2004) 119-125
    • (2004) Semin Thromb Hemost , vol.30 , pp. 119-125
    • Nie, D.1    Honn, K.V.2
  • 2
    • 0032815072 scopus 로고    scopus 로고
    • Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis
    • Fischer S.M., Lo H.H., Gordon G.B., et al. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis. Mol Carcinog 25 (1999) 231-240
    • (1999) Mol Carcinog , vol.25 , pp. 231-240
    • Fischer, S.M.1    Lo, H.H.2    Gordon, G.B.3
  • 3
    • 0034655238 scopus 로고    scopus 로고
    • Chemoprevention of breast cancer in rats by celecoxib, a cyclooxygenase 2 inhibitor
    • Harris R.E., Alshafie G.A., Abou-Issa H., and Seibert K. Chemoprevention of breast cancer in rats by celecoxib, a cyclooxygenase 2 inhibitor. Cancer Res 60 (2000) 2101-2103
    • (2000) Cancer Res , vol.60 , pp. 2101-2103
    • Harris, R.E.1    Alshafie, G.A.2    Abou-Issa, H.3    Seibert, K.4
  • 4
    • 0035571588 scopus 로고    scopus 로고
    • Dose-response effects of the COX-2 inhibitor, celecoxib, on the chemoprevention of mammary carcinogenesis
    • Abou-Issa H.M., Alshafie G.A., Seibert K., Koki A.T., Masferrer J.L., and Harris R.E. Dose-response effects of the COX-2 inhibitor, celecoxib, on the chemoprevention of mammary carcinogenesis. Anticancer Res 21 (2001) 3425-3432
    • (2001) Anticancer Res , vol.21 , pp. 3425-3432
    • Abou-Issa, H.M.1    Alshafie, G.A.2    Seibert, K.3    Koki, A.T.4    Masferrer, J.L.5    Harris, R.E.6
  • 5
    • 0032006784 scopus 로고    scopus 로고
    • Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis
    • Kawamori T., Rao C.V., Seibert K., and Reddy B.S. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. Cancer Res 58 (1998) 409-412
    • (1998) Cancer Res , vol.58 , pp. 409-412
    • Kawamori, T.1    Rao, C.V.2    Seibert, K.3    Reddy, B.S.4
  • 6
    • 0032702213 scopus 로고    scopus 로고
    • Cyclooxygenase 2 inhibitors: discovery, selectivity and the future
    • Marnett L.J., and Kalgutkar A.S. Cyclooxygenase 2 inhibitors: discovery, selectivity and the future. Trends Pharmacol Sci 20 (1999) 465-469
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 465-469
    • Marnett, L.J.1    Kalgutkar, A.S.2
  • 7
    • 0034644396 scopus 로고    scopus 로고
    • Gastrointestinal toxicity with celecoxib vs. nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: a randomized controlled trial Celecoxib Long-term Arthritis Safety Study
    • Silverstein F.E., Faich G., Goldstein J.L., et al. Gastrointestinal toxicity with celecoxib vs. nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: a randomized controlled trial Celecoxib Long-term Arthritis Safety Study. JAMA 284 (2000) 1247-1255
    • (2000) JAMA , vol.284 , pp. 1247-1255
    • Silverstein, F.E.1    Faich, G.2    Goldstein, J.L.3
  • 9
    • 0034885485 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 (COX-2) mRNA in human colorectal adenomas
    • Hasegawa K., Ichikawa W., Fujita T., et al. Expression of cyclooxygenase-2 (COX-2) mRNA in human colorectal adenomas. Eur J Cancer 37 (2001) 1469-1474
    • (2001) Eur J Cancer , vol.37 , pp. 1469-1474
    • Hasegawa, K.1    Ichikawa, W.2    Fujita, T.3
  • 10
    • 3142782285 scopus 로고    scopus 로고
    • Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation
    • Pozzi A., Yan X., Macias-Perez I., et al. Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation. J Biol Chem 279 (2004) 29797-29804
    • (2004) J Biol Chem , vol.279 , pp. 29797-29804
    • Pozzi, A.1    Yan, X.2    Macias-Perez, I.3
  • 12
    • 20144365496 scopus 로고    scopus 로고
    • Adenoma Prevention with Celecoxib (APC) Study Investigators Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
    • Solomon S.D., McMurray J.J., Pfeffer M.A., et al. Adenoma Prevention with Celecoxib (APC) Study Investigators Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 352 (2005) 1071-1080
    • (2005) N Engl J Med , vol.352 , pp. 1071-1080
    • Solomon, S.D.1    McMurray, J.J.2    Pfeffer, M.A.3
  • 13
    • 14944371100 scopus 로고    scopus 로고
    • Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery
    • Nussmeier N.A., Whelton A.A., Brown M.T., et al. Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery. N Engl J Med 352 (2005) 1081-1091
    • (2005) N Engl J Med , vol.352 , pp. 1081-1091
    • Nussmeier, N.A.1    Whelton, A.A.2    Brown, M.T.3
  • 14
    • 0028785372 scopus 로고
    • Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer
    • Gao X., Grignon D.J., Chbihi T., et al. Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer. Urology 46 (1995) 227-237
    • (1995) Urology , vol.46 , pp. 227-237
    • Gao, X.1    Grignon, D.J.2    Chbihi, T.3
  • 15
    • 0032530236 scopus 로고    scopus 로고
    • Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth
    • Nie D., Hillman G.G., Geddes T., et al. Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth. Cancer Res 58 (1998) 4047-4051
    • (1998) Cancer Res , vol.58 , pp. 4047-4051
    • Nie, D.1    Hillman, G.G.2    Geddes, T.3
  • 16
    • 21144442338 scopus 로고    scopus 로고
    • Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer
    • discussion 946-7
    • Heslin M.J., Hawkins A., Boedefeld W., et al. Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer. Ann Surg 241 (2005) 941-946 discussion 946-7
    • (2005) Ann Surg , vol.241 , pp. 941-946
    • Heslin, M.J.1    Hawkins, A.2    Boedefeld, W.3
  • 17
    • 21144459060 scopus 로고    scopus 로고
    • Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors
    • Jiang J.G., Chen C.L., Card J.W., et al. Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. Cancer Res 65 (2005) 4707-4715
    • (2005) Cancer Res , vol.65 , pp. 4707-4715
    • Jiang, J.G.1    Chen, C.L.2    Card, J.W.3
  • 18
    • 0036080081 scopus 로고    scopus 로고
    • P-450 metabolites of arachidonic acid in the control of cardiovascular function
    • Roman R.J. P-450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol Rev 82 (2002) 131-185
    • (2002) Physiol Rev , vol.82 , pp. 131-185
    • Roman, R.J.1
  • 19
    • 0032997280 scopus 로고    scopus 로고
    • Kinetic profile of the rat CYP4A isoforms: arachidonic acid metabolism and isoform-specific inhibitors
    • Nguyen X., Wang M.H., Reddy K.M., Falck J.R., and Schwartzman M.L. Kinetic profile of the rat CYP4A isoforms: arachidonic acid metabolism and isoform-specific inhibitors. Am J Physiol 276 (1999) R1691-R1700
    • (1999) Am J Physiol , vol.276
    • Nguyen, X.1    Wang, M.H.2    Reddy, K.M.3    Falck, J.R.4    Schwartzman, M.L.5
  • 20
    • 0030589540 scopus 로고    scopus 로고
    • Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein
    • Wang M.H., Stec D.E., Balazy M., et al. Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein. Arch Biochem Biophys 336 (1996) 240-250
    • (1996) Arch Biochem Biophys , vol.336 , pp. 240-250
    • Wang, M.H.1    Stec, D.E.2    Balazy, M.3
  • 21
    • 0032497411 scopus 로고    scopus 로고
    • Molecular, enzymatic, and regulatory characterization of rat kidney cytochromes P450 4A2 and 4A3
    • Helvig C., Dishman E., and Capdevila J.H. Molecular, enzymatic, and regulatory characterization of rat kidney cytochromes P450 4A2 and 4A3. Biochemistry 37 (1998) 12546-12558
    • (1998) Biochemistry , vol.37 , pp. 12546-12558
    • Helvig, C.1    Dishman, E.2    Capdevila, J.H.3
  • 22
    • 0033955218 scopus 로고    scopus 로고
    • Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases
    • Hoch U., Zhang Z., Kroetz D.L., and Ortiz de Montellano P.R. Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases. Arch Biochem Biophys 373 (2000) 63-71
    • (2000) Arch Biochem Biophys , vol.373 , pp. 63-71
    • Hoch, U.1    Zhang, Z.2    Kroetz, D.L.3    Ortiz de Montellano, P.R.4
  • 23
    • 13244292649 scopus 로고    scopus 로고
    • Inhibitors of cytochrome P450 4A suppress angiogenic responses
    • Chen P., Guo M., Wygle D., et al. Inhibitors of cytochrome P450 4A suppress angiogenic responses. Am J Pathol 166 (2005) 615-624
    • (2005) Am J Pathol , vol.166 , pp. 615-624
    • Chen, P.1    Guo, M.2    Wygle, D.3
  • 24
    • 0029907840 scopus 로고    scopus 로고
    • Cytochrome P-450-dependent HETEs: profile of biological activity and stimulation by vasoactive peptides
    • Carroll M.A., Balazy M., Margiotta P., Huang D.D., Falck J.R., and McGiff J.C. Cytochrome P-450-dependent HETEs: profile of biological activity and stimulation by vasoactive peptides. Am J Physiol 271 (1996) R863-R869
    • (1996) Am J Physiol , vol.271
    • Carroll, M.A.1    Balazy, M.2    Margiotta, P.3    Huang, D.D.4    Falck, J.R.5    McGiff, J.C.6
  • 26
    • 0035986058 scopus 로고    scopus 로고
    • CYP4A mRNA, protein, and product in rat lungs: novel localization in vascular endothelium
    • Zhu D., Zhang C., Medhora M., and Jacobs E.R. CYP4A mRNA, protein, and product in rat lungs: novel localization in vascular endothelium. J Appl Physiol 93 (2002) 330-337
    • (2002) J Appl Physiol , vol.93 , pp. 330-337
    • Zhu, D.1    Zhang, C.2    Medhora, M.3    Jacobs, E.R.4
  • 27
    • 13244270236 scopus 로고    scopus 로고
    • P450 in the angiogenesis affair: the unusual suspect
    • Ljubimov A.V., and Grant M.B. P450 in the angiogenesis affair: the unusual suspect. Am J Pathol 166 (2005) 341-344
    • (2005) Am J Pathol , vol.166 , pp. 341-344
    • Ljubimov, A.V.1    Grant, M.B.2
  • 28
    • 27144552930 scopus 로고    scopus 로고
    • Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N′-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A
    • Guo M., Roman R.J., Falck J.R., Edwards P.A., and Scicli A.G. Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N′-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A. J Pharmacol Exp Ther 315 (2005) 526-533
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 526-533
    • Guo, M.1    Roman, R.J.2    Falck, J.R.3    Edwards, P.A.4    Scicli, A.G.5
  • 30
    • 1042279546 scopus 로고    scopus 로고
    • Smooth muscle-specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels
    • Jiang M., Mezentsev A., Kemp R., et al. Smooth muscle-specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels. Circ Res 94 (2004) 167-174
    • (2004) Circ Res , vol.94 , pp. 167-174
    • Jiang, M.1    Mezentsev, A.2    Kemp, R.3
  • 31
    • 0031583917 scopus 로고    scopus 로고
    • Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 in endothelial cells via p42/p44 mitogen-activated protein kinase
    • Wheeler-Jones C., Abu-Ghazaleh R., Cospedal R., Houliston R.A., Martin J., and Zachary I. Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 in endothelial cells via p42/p44 mitogen-activated protein kinase. FEBS Lett 420 (1997) 28-32
    • (1997) FEBS Lett , vol.420 , pp. 28-32
    • Wheeler-Jones, C.1    Abu-Ghazaleh, R.2    Cospedal, R.3    Houliston, R.A.4    Martin, J.5    Zachary, I.6
  • 32
    • 0028930542 scopus 로고
    • Activation of cytosolic phospholipase A2 by basic fibroblast growth factor via a p42 mitogen-activated protein kinase-dependent phosphorylation pathway in endothelial cells
    • Sa G., Murugesan G., Jaye M., Ivashchenko Y., and Fox P.L. Activation of cytosolic phospholipase A2 by basic fibroblast growth factor via a p42 mitogen-activated protein kinase-dependent phosphorylation pathway in endothelial cells. J Biol Chem 270 (1995) 2360-2366
    • (1995) J Biol Chem , vol.270 , pp. 2360-2366
    • Sa, G.1    Murugesan, G.2    Jaye, M.3    Ivashchenko, Y.4    Fox, P.L.5
  • 33
    • 0141679474 scopus 로고    scopus 로고
    • Key role of PLC-gamma in EGF protection of epithelial barrier against iNOS upregulation and F-actin nitration and disassembly
    • Banan A., Zhang L.J., Shaikh M., Fields J.Z., Farhadi A., and Keshavarzian A. Key role of PLC-gamma in EGF protection of epithelial barrier against iNOS upregulation and F-actin nitration and disassembly. Am J Physiol Cell Physiol 285 (2003) C977-C993
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Banan, A.1    Zhang, L.J.2    Shaikh, M.3    Fields, J.Z.4    Farhadi, A.5    Keshavarzian, A.6
  • 34
    • 0027384226 scopus 로고
    • RAS is required for epidermal growth factor-stimulated arachidonic acid release in rat-1 fibroblasts
    • Warner L.C., Hack N., Egan S.E., Goldberg H.J., Weinberg R.A., and Skorecki K.L. RAS is required for epidermal growth factor-stimulated arachidonic acid release in rat-1 fibroblasts. Oncogene 8 (1993) 3249-3255
    • (1993) Oncogene , vol.8 , pp. 3249-3255
    • Warner, L.C.1    Hack, N.2    Egan, S.E.3    Goldberg, H.J.4    Weinberg, R.A.5    Skorecki, K.L.6
  • 35
    • 33845327129 scopus 로고    scopus 로고
    • Jacobs ER, Zhu D, Gruenloh SK, Lopez B, Medhora M. VEGF-induced relaxation of pulmonary arteries is mediated by endothelial cytochrome P450 hydroxylase. Am J Physiol, in press (available online).
  • 36
    • 0032514708 scopus 로고    scopus 로고
    • 20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin-dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells
    • Muthalif M.M., Benter I.F., Karzoun N., et al. 20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin-dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. Proc Natl Acad Sci USA 95 (1998) 12701-12706
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12701-12706
    • Muthalif, M.M.1    Benter, I.F.2    Karzoun, N.3
  • 37
    • 23944476083 scopus 로고    scopus 로고
    • Endothelial microparticles affect angiogenesis in vitro: role of oxidative stress
    • Mezentsev A., Merks R.M., O'Riordan E., et al. Endothelial microparticles affect angiogenesis in vitro: role of oxidative stress. Am J Physiol Heart Circ Physiol 289 (2005) H1106-H1114
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Mezentsev, A.1    Merks, R.M.2    O'Riordan, E.3
  • 38
    • 0036257467 scopus 로고    scopus 로고
    • Corneal epithelial VEGF and cytochrome P450 4B1 expression in a rabbit model of closed eye contact lens wear
    • Mastyugin V., Mosaed S., Bonazzi A., Dunn M.W., and Schwartzman M.L. Corneal epithelial VEGF and cytochrome P450 4B1 expression in a rabbit model of closed eye contact lens wear. Curr Eye Res 23 (2001) 1-10
    • (2001) Curr Eye Res , vol.23 , pp. 1-10
    • Mastyugin, V.1    Mosaed, S.2    Bonazzi, A.3    Dunn, M.W.4    Schwartzman, M.L.5
  • 39
    • 0034109792 scopus 로고    scopus 로고
    • Cerebral microvascular endothelial cell tube formation: role of astrocytic epoxyeicosatrienoic acid release
    • Munzenmaier D.H., and Harder D.R. Cerebral microvascular endothelial cell tube formation: role of astrocytic epoxyeicosatrienoic acid release. Am J Physiol Heart Circ Physiol 278 (2000) H1163-H1167
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Munzenmaier, D.H.1    Harder, D.R.2
  • 40
    • 0036901546 scopus 로고    scopus 로고
    • Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic acid
    • Zhang C., and Harder D.R. Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic acid. Stroke 33 (2002) 2957-2964
    • (2002) Stroke , vol.33 , pp. 2957-2964
    • Zhang, C.1    Harder, D.R.2
  • 41
    • 0037230201 scopus 로고    scopus 로고
    • Epoxygenase-driven angiogenesis in human lung microvascular endothelial cells
    • Medhora M., Daniels J., Mundey K., et al. Epoxygenase-driven angiogenesis in human lung microvascular endothelial cells. Am J Physiol Heart Circ Physiol 284 (2003) H215-H224
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Medhora, M.1    Daniels, J.2    Mundey, K.3
  • 42
    • 0032238183 scopus 로고    scopus 로고
    • Functional role of epoxyeicosatrienoic acids and their production in astrocytes: approaches for gene transfer and therapy
    • review
    • Medhora M., and Harder D. Functional role of epoxyeicosatrienoic acids and their production in astrocytes: approaches for gene transfer and therapy. Int J Mol Med 2 (1998) 661-669 review
    • (1998) Int J Mol Med , vol.2 , pp. 661-669
    • Medhora, M.1    Harder, D.2
  • 43
    • 0037387681 scopus 로고    scopus 로고
    • Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor (EGFR)
    • Michaelis U.R., Fisslthaler B., Medhora M., Harder D., Fleming I., and Busse R. Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor (EGFR). FASEB J 17 (2003) 770-772
    • (2003) FASEB J , vol.17 , pp. 770-772
    • Michaelis, U.R.1    Fisslthaler, B.2    Medhora, M.3    Harder, D.4    Fleming, I.5    Busse, R.6
  • 44
    • 0037013216 scopus 로고    scopus 로고
    • Cytochrome P450 2C9-induced endothelial cell proliferation involves induction of mitogen-activated protein (MAP) kinase phosphatase-1, inhibition of the c-Jun N-terminal kinase, and up-regulation of cyclin D1
    • Potente M., Michaelis U.R., Fisslthaler B., Busse R., and Fleming I. Cytochrome P450 2C9-induced endothelial cell proliferation involves induction of mitogen-activated protein (MAP) kinase phosphatase-1, inhibition of the c-Jun N-terminal kinase, and up-regulation of cyclin D1. J Biol Chem 277 (2002) 15671-15676
    • (2002) J Biol Chem , vol.277 , pp. 15671-15676
    • Potente, M.1    Michaelis, U.R.2    Fisslthaler, B.3    Busse, R.4    Fleming, I.5
  • 45
    • 22844446840 scopus 로고    scopus 로고
    • Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids
    • Pozzi A., Macias-Perez I., Abair T., et al. Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids. J Biol Chem 280 (2005) 27138-27146
    • (2005) J Biol Chem , vol.280 , pp. 27138-27146
    • Pozzi, A.1    Macias-Perez, I.2    Abair, T.3
  • 46
    • 30544449595 scopus 로고    scopus 로고
    • Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis
    • Michaelis U.R., Fisslthaler B., Barbosa-Sicard E., Falck J.R., Fleming I., and Busse R. Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis. J Cell Sci 118 (2005) 5489-5498
    • (2005) J Cell Sci , vol.118 , pp. 5489-5498
    • Michaelis, U.R.1    Fisslthaler, B.2    Barbosa-Sicard, E.3    Falck, J.R.4    Fleming, I.5    Busse, R.6
  • 47
    • 22944448688 scopus 로고    scopus 로고
    • Arachidonic acid epoxygenase metabolites stimulate endothelial cell growth and angiogenesis via mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways
    • Wang Y., Wei X., Xiao X., et al. Arachidonic acid epoxygenase metabolites stimulate endothelial cell growth and angiogenesis via mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways. J Pharmacol Exp Ther 314 (2005) 522-532
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 522-532
    • Wang, Y.1    Wei, X.2    Xiao, X.3
  • 48
    • 33644852338 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 is a downstream mediator of phosphatidylinositol 3-kinase-Akt signaling in 14,15-epoxyeicosatrienoic acid-induced angiogenesis
    • Zhang B., Cao H., and Rao G.N. Fibroblast growth factor-2 is a downstream mediator of phosphatidylinositol 3-kinase-Akt signaling in 14,15-epoxyeicosatrienoic acid-induced angiogenesis. J Biol Chem 281 (2006) 905-914
    • (2006) J Biol Chem , vol.281 , pp. 905-914
    • Zhang, B.1    Cao, H.2    Rao, G.N.3
  • 49
    • 33845294773 scopus 로고    scopus 로고
    • Dhanasekaran A, Al-Saghir R, Lopez B, et al. Protective effects of epoxyeicosatrienoic acids (EETs) on human endothelial cells from the pulmonary and coronary vasculature. Am J Physiol Heart Circ Physiol, in press (available online).
  • 50
    • 33845322987 scopus 로고    scopus 로고
    • Role of cytochrome P450-catalyzed metabolites of arachidonic acid in angiogenesis
    • Narayanan J., Mundey K., Sharma M., and Medhora M. Role of cytochrome P450-catalyzed metabolites of arachidonic acid in angiogenesis. Rec Res Dev Physiol 1 Part II (2003) 793-800
    • (2003) Rec Res Dev Physiol , vol.1 , Issue.PART II , pp. 793-800
    • Narayanan, J.1    Mundey, K.2    Sharma, M.3    Medhora, M.4
  • 51
    • 33645815886 scopus 로고    scopus 로고
    • Endothelium-derived epoxyeicosatrienoic acids and vascular functions
    • Fleming I., and Busse R. Endothelium-derived epoxyeicosatrienoic acids and vascular functions. Hypertension 47 (2006) 629-633
    • (2006) Hypertension , vol.47 , pp. 629-633
    • Fleming, I.1    Busse, R.2
  • 52
    • 0037501115 scopus 로고    scopus 로고
    • Focal adhesion kinase is expressed in the angiogenic blood vessels of malignant astrocytic tumors in vivo and promotes capillary tube formation of brain microvascular endothelial cells
    • Haskell H., Natarajan M., Hecker T.P., et al. Focal adhesion kinase is expressed in the angiogenic blood vessels of malignant astrocytic tumors in vivo and promotes capillary tube formation of brain microvascular endothelial cells. Clin Cancer Res 9 (2003) 2157-2165
    • (2003) Clin Cancer Res , vol.9 , pp. 2157-2165
    • Haskell, H.1    Natarajan, M.2    Hecker, T.P.3
  • 53
    • 0033002997 scopus 로고    scopus 로고
    • Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2
    • Owen J.D., Ruest P.J., Fry D.W., and Hanks S.K. Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2. Mol Cell Biol 19 (1999) 4806-4818
    • (1999) Mol Cell Biol , vol.19 , pp. 4806-4818
    • Owen, J.D.1    Ruest, P.J.2    Fry, D.W.3    Hanks, S.K.4
  • 54
    • 0034720452 scopus 로고    scopus 로고
    • Control of smooth muscle cell proliferation and phenotype by integrin signaling through focal adhesion kinase
    • Morla A.O., and Mogford J.E. Control of smooth muscle cell proliferation and phenotype by integrin signaling through focal adhesion kinase. Biochem Biophys Res Commun 272 (2000) 298-302
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 298-302
    • Morla, A.O.1    Mogford, J.E.2
  • 55
    • 0036277938 scopus 로고    scopus 로고
    • Neuroprotection and P450 2C11 upregulation after experimental transient ischemic attack
    • Alkayed N.J., Goyagi T., Joh H.D., et al. Neuroprotection and P450 2C11 upregulation after experimental transient ischemic attack. Stroke 33 (2002) 1677-1684
    • (2002) Stroke , vol.33 , pp. 1677-1684
    • Alkayed, N.J.1    Goyagi, T.2    Joh, H.D.3
  • 57
    • 4444236138 scopus 로고    scopus 로고
    • Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway
    • Seubert J., Yang B., Bradbury J.A., et al. Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. Circ Res 95 (2004) 506-514
    • (2004) Circ Res , vol.95 , pp. 506-514
    • Seubert, J.1    Yang, B.2    Bradbury, J.A.3
  • 58
    • 33845296110 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids (EETs) protect cardiovascular cells from apoptosis mediated by caspase 3-dependent pathways
    • Dhanasekaran A., Stephanie G., Jacobs E.R., and Medhora M. Epoxyeicosatrienoic acids (EETs) protect cardiovascular cells from apoptosis mediated by caspase 3-dependent pathways. FASEB J 20 (2006) A123
    • (2006) FASEB J , vol.20
    • Dhanasekaran, A.1    Stephanie, G.2    Jacobs, E.R.3    Medhora, M.4
  • 59
    • 0141996422 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-2: its unique signaling and specific ligand. VEGF-E.
    • Shibuya M. Vascular endothelial growth factor receptor-2: its unique signaling and specific ligand. VEGF-E. Cancer Sci 94 (2003) 751-756
    • (2003) Cancer Sci , vol.94 , pp. 751-756
    • Shibuya, M.1
  • 60
    • 0035725998 scopus 로고    scopus 로고
    • Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis
    • Chen J.K., Capdevila J., and Harris R.C. Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis. Mol Cell Biol 21 (2001) 6322-6331
    • (2001) Mol Cell Biol , vol.21 , pp. 6322-6331
    • Chen, J.K.1    Capdevila, J.2    Harris, R.C.3
  • 61
    • 33845348893 scopus 로고    scopus 로고
    • Cytochrome P450 epoxygenase-derived lipopolysaccharide-induced apoptosis of endothelial cells
    • Wang Y., Yang S., and Wang D.W. Cytochrome P450 epoxygenase-derived lipopolysaccharide-induced apoptosis of endothelial cells. Winter Eicsoanoid Conference (2006) 30
    • (2006) Winter Eicsoanoid Conference , pp. 30
    • Wang, Y.1    Yang, S.2    Wang, D.W.3
  • 62
    • 0347763396 scopus 로고    scopus 로고
    • The focal segmental glomerulosclerosis permeability factor: biochemical characteristics and biological effects
    • Sharma M., Sharma R., McCarthy E.T., and Savin V.J. The focal segmental glomerulosclerosis permeability factor: biochemical characteristics and biological effects. Exp Biol Med (Maywood) 229 (2004) 85-98
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 85-98
    • Sharma, M.1    Sharma, R.2    McCarthy, E.T.3    Savin, V.J.4
  • 64
    • 23244463577 scopus 로고    scopus 로고
    • Chick chorioallantoic membrane as an in vivo model to study vasoreactivity: characterization of development-dependent hyperemia induced by epoxyeicosatrienoic acids (EETs)
    • Dunn L.K., Gruenloh S.K., Dunn B.E., et al. Chick chorioallantoic membrane as an in vivo model to study vasoreactivity: characterization of development-dependent hyperemia induced by epoxyeicosatrienoic acids (EETs). Anat Rec A Discov Mol Cell Evol Biol 285 (2005) 771-780
    • (2005) Anat Rec A Discov Mol Cell Evol Biol , vol.285 , pp. 771-780
    • Dunn, L.K.1    Gruenloh, S.K.2    Dunn, B.E.3
  • 65
    • 0037144475 scopus 로고    scopus 로고
    • The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands
    • Cowart L.A., Wei S., Hsu M.H., et al. The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands. J Biol Chem 277 (2002) 35105-35112
    • (2002) J Biol Chem , vol.277 , pp. 35105-35112
    • Cowart, L.A.1    Wei, S.2    Hsu, M.H.3


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