Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor

Journal of Biological Chemistry

Volumn 274, Issue 8, 1999, Pages 4764-4769

  Chen, Jian Kang ^a   Wang, Dao Wen ^a   Falck, John R ^c   Capdevila, Jorge ^a,b   Harris, Raymond C ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

14,15 EPOXY 5,8,11 ICOSATRIENOIC ACID; CYTOCHROME P450; EPIDERMAL GROWTH FACTOR; PROSTAGLANDIN SYNTHASE;

ANIMAL CELL; ARTICLE; DNA SYNTHESIS INHIBITION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; IMMUNOREACTIVITY; MITOGENESIS; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SECOND MESSENGER; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

8,11,14-EICOSATRIENOIC ACID; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; EPIDERMAL GROWTH FACTOR; LLC-PK1 CELLS; MITOGENS; OXYGENASES; PHOSPHORYLATION; SECOND MESSENGER SYSTEMS; SWINE; TRANSFECTION;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0033582481     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.8.4764     Document Type: Article

References (37)

1. Needleman, P., Turk, J., Jakschik, B. A., Morrison, A. R., and Lefkowitz, J. B. (1986) Annu. Rev. Biochem. 55, 69-102
2. Di Marzo, V. (1995) Prostaglandins Leukotrienes Essent. Fatty Acids 53, 239-254
3. Baker, R. R. (1990) Clin. Biochem. 23, 455-458
4. Vane, J. R., and Botting, R. M. (1997) Semin. Arthritis Rheum. 26, 2-10
5. Needleman, P., and Isakson, P. C. (1997) J. Rheumatol 24, 6-9
6. Makita, K., Falck, J. R., and Capdevila, J. (1996) FASEB J. 10, 1456-1463
7. Graham-Lorence, S., Truan, G., Peterson, J. A., Falck, J. R., Wei, S., Helvig, C., and Capdevila, J. H. (1997) J. Biol. Chem. 272, 1127-1135
8. Chen, J.-K., Falck, J. R., Reddy, K. M., Capdevila, J. H., and Harris, R. C. (1998) J. Bull. Chem. 273, 29254-29261
9. Amsler, K., and Cook, J. S. (1982) Am. J. Physiol 242, C94-C101
10. Capdevila, J. H., Dishman, E., Karara, A., and Falck, J. R. (1991) Methods Enzymol. 206, 441-453
11. Akiyama T., Ishida J., Nakagawa S., Ogawara H., Watanabe S., Itch N., Shibuya M., and Fukami Y. (1987) J. Biol. Chem. 262, 5592-5595
12. Straub S. G., and Sharp G. W. G. (1996) J. Biol. Chem. 271, 1660-1668
13. Vlahos, C. J., Matter, W. F., Hui, K. Y., and Brown, R. F. (1994) J. Biol. Chem. 269, 5241-5248
14. Dudley, D. T., Pang, L., Decker, S. J., Bridges, A. J., and Saltiel, A. R. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7686-7689
15. Muerhoff, A. S., Williams, D. E., Reich, N. O., CaJacob, C. A., Ortiz de Montellano, P. R., and Masters, B. S. S. (1989) J. Biol. Chem. 264, 749-756
16. Capdevila, J. H., Falck, J. R., and Estabrook, R. W. (1992) FASEB J. 6, 731-736
17. VanRollins, M., Kochanek, P. M., Evans, R. W., Schiding, J. K., and Nemoto, E. M. (1995) Biochim. Biophys. Acta 1256, 263-274
18. Catella, F., Lawson, J. A., Fitzgerald, D. J., and Fitgerald, G. A. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 5893-5897
19. Harder, D. R., Campbell, W. B., and Roman, R. J. (1995) J. Vasc. Res. 32, 79-92
20. Takahashi, K., Capdevila, J., Karara, A., Falck, J. R., Jacobson, H. R., and Badr, K. F. (1990) Am. J. Physiol. 258, F781-F789
21. Katoh, T., Takahashi, K., Capdevila, J., Karara, A., Falck, J. R., Jacobson, H. R., and Badr, K. F. (1991) Am. J. Physiol. 261, F578-F586
22. Harris, R. C., Homma, T., Jacobson, H. R., and Capdevila, J. (1990) J. Cell. Physiol. 144, 429-443
23. Campbell, W. B., Gebremedhin, D., Pratt, P. F., and Harder, D. R. (1996) Circ. Res. 78, 415-423
24. Graier, W. F., Simecek, S., and Sturek, M. (1995) J. Physiol. 482, 259-274
25. Burns, K. D., Capdevila, J. H., Wei, S., Breyer, M. D., Homma, T., and Harris, R. C. (1995) Am. J. Physiol. 269, C831-C840
26. Schieffer, B., Paxton, W. G., Chai, Q., Marrero, M. B., and Bernstein, K. E. (1996) J. Biol. Chem. 271, 10329-10333
27. Della Rocca, G. J., van Biesen, T., Daaka, Y., Luttrell, D. K., Luttrell, L. M., and Lefkowitz, R. J. (1997) J. Biol. Chem. 272, 19125-19132
28. Dikic, I., Tokiwa, G., Lev, S., Courtneidge, S. A., and Schlessinger, J. (1996) Nature 383, 547-550
29. Luttrell, L. M., Della Rocca, G. J., van Biesen, T., Luttrell, D. K., and Lefkowitz, R. J. (1997) J. Biol. Chem. 272, 4637-4644
30. Linseman, D. A., Benjamin, C. W., and Jones, D. A. (1995) J. Biol. Chem. 270, 12563-12568
31. Madhun, Z. T., Goldthwait, D. A., McKay, D., Hopfer, U., and Douglas, J. G. (1991) J. Clin. Invest. 88, 456-461
32. Ribeiro, C. M., Dubay, G. R., Falck, J. R., and Mandel, L. J. (1994) Am. J. Physiol. 266, F497-F505
33. Quilley, J., Fulton, D., and McGiff, J. C. (1997) Biochemical Pharmacol. 54, 1054-1070
34. Wong, P. Y., Lin, K. T., Yan, Y. T., Ahern, D., Iles, J., Shen, S. Y., Bhatt, R. K., and Falck, J. R. (1993) J. Lipid Mediators 6, 199-208
35. Wong, P. Y. K., Lai, P. S., Shen, S. Y., Belosludtsev, Y. Y., and Falck, J. R. (1997) J. Lipid Mediat. Cell Signal. 16, 155-169
36. Hu, S., and Kim, H. S. (1993) Eur. J. Pharmacol. 230, 215-221
37. Li, P. L., and Campbell, W. B. (1997) Circ. Res. 80, 877-884