Cyclopeptide Smac mimetics as antagonists of IAP proteins

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 10, 2010, Pages 3043-3046

  Sun, Haiying ^a   Liu, Liu ^a   Lu, Jianfeng ^a   Qiu, Su ^a   Yang, Chao Yie ^a   Yi, Han ^a   Wang, Shaomeng ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Apoptosis inducers; IAP antagonists; New anticancer agents; Smac mimetics

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 9; CYCLOPEPTIDE; INHIBITOR OF APOPTOSIS PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; X LINKED INHIBITOR OF APOPTOSIS;

ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; PEPTIDE ANALYSIS; PROTEIN FUNCTION; PROTEIN INTERACTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 7; CASPASE 9; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; OLIGOPEPTIDES; PEPTIDES, CYCLIC; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; TRIAZOLES; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 77952099836     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.03.114     Document Type: Article

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