An alternative interpretation of the amyloid Aβ hypothesis with regard to the pathogenesis of Alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 26, 2005, Pages 9093-9098

  Marchesi, Vincent T ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Neurodegeneration

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; MEMBRANE PROTEIN; NICASTRIN; OLIGOMER; PEN 2 PROTEIN; PRESENILIN 1; PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; DEGENERATIVE DISEASE; EXTRACELLULAR SPACE; GXXG MOTIF; HUMAN; LIPID BILAYER; NERVE CELL NECROSIS; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN SECRETION; REVIEW; SENILE PLAQUE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; DIMERIZATION; HUMANS; LIPID BILAYERS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NEURONS; PEPTIDES; PRESENILIN-1; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM DODECYL SULFATE; TEMPERATURE;

EID: 21544465581     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0503181102     Document Type: Review

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