-
1
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen, G. & Goeddel, D.V. TNF-R1 signaling: A beautiful pathway. Science 296, 1634-1635 (2002).
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
2
-
-
0037276438
-
Tumor necrosis factor signaling
-
Wajant, H., Pfizenmaier, K. & Scheurich, P. Tumor necrosis factor signaling. Cell Death Differ. 10, 45-65 (2003).
-
(2003)
Cell Death Differ
, vol.10
, pp. 45-65
-
-
Wajant, H.1
Pfizenmaier, K.2
Scheurich, P.3
-
3
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-κB activity
-
Karin, M. & Ben-Neriah, Y. Phosphorylation meets ubiquitination: The control of NF-κB activity. Annu. Rev. Immunol. 18, 621-663 (2000).
-
(2000)
Annu. Rev. Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
4
-
-
0033106149
-
A ubiquitin ligase complex essential for the NF-κB, Wnt/Wingless, and Hedgehog signaling pathways
-
Maniatis, T. A ubiquitin ligase complex essential for the NF-κB, Wnt/Wingless, and Hedgehog signaling pathways. Genes Dev. 13, 505-510 (1999).
-
(1999)
Genes Dev
, vol.13
, pp. 505-510
-
-
Maniatis, T.1
-
5
-
-
39049183044
-
Regulation and function of IKK and IKK-related kinases
-
Häcker, H. & Karin, M. Regulation and function of IKK and IKK-related kinases. Sci. STKE 357, re13 (2006).
-
(2006)
Sci. STKE
, vol.357
-
-
Häcker, H.1
Karin, M.2
-
6
-
-
0034661272
-
Complete lack of NF-κB activity in IKK1 and IKK2 double deficient mice: Additional defect in neurulation
-
Li, Q., Estepa, G., Memet, S., Israel, A. & Verma, I.M. Complete lack of NF-κB activity in IKK1 and IKK2 double deficient mice: Additional defect in neurulation. Genes Dev. 14, 1729-1733 (2000).
-
(2000)
Genes Dev
, vol.14
, pp. 1729-1733
-
-
Li, Q.1
Estepa, G.2
Memet, S.3
Israel, A.4
Verma, I.M.5
-
7
-
-
0036234459
-
Missing pieces in the NF-κB puzzle
-
Ghosh, S. & Karin, M. Missing pieces in the NF-κB puzzle. Cell 109, S81-S96 (2002).
-
(2002)
Cell
, vol.109
-
-
Ghosh, S.1
Karin, M.2
-
8
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation
-
Yamaoka, S. et al. Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation. Cell 93, 1231-1240 (1998).
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
-
9
-
-
0033537719
-
Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation
-
Delhase, M., Hayakawa, M., Chen, Y. & Karin, M. Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation. Science 284, 309-313 (1999).
-
(1999)
Science
, vol.284
, pp. 309-313
-
-
Delhase, M.1
Hayakawa, M.2
Chen, Y.3
Karin, M.4
-
10
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
Mercurio, F. et al. IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation. Science 278, 860-866 (1997).
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
-
11
-
-
0027988165
-
Genotoxic stress confers preferential and coordinate messenger RNA stability on the five gadd genes
-
Jackman, J., Alamo, I. & Fornace, A.J. Jr. Genotoxic stress confers preferential and coordinate messenger RNA stability on the five gadd genes. Cancer Res. 54, 5656-5662 (1994).
-
(1994)
Cancer Res
, vol.54
, pp. 5656-5662
-
-
Jackman, J.1
Alamo, I.2
Fornace Jr., A.J.3
-
13
-
-
0035399464
-
Combinatorial control of protein phosphatase-1
-
Bollen, M. Combinatorial control of protein phosphatase-1. Trends Biochem. Sci. 26, 426-431 (2001).
-
(2001)
Trends Biochem. Sci
, vol.26
, pp. 426-431
-
-
Bollen, M.1
-
14
-
-
0030977268
-
Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1
-
Egloff, M.P. et al. Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1. EMBO J. 16, 1876-1887 (1997).
-
(1997)
EMBO J
, vol.16
, pp. 1876-1887
-
-
Egloff, M.P.1
-
15
-
-
0037316409
-
Ubiquitin signals protein trafficking via interaction with a novel ubquitin binding domain in the membrane fusion regulator, Vps9p
-
Donaldson, K.M., Yin, H., Gekakis, N., Supek, F. & Hoazeiro, C.A. Ubiquitin signals protein trafficking via interaction with a novel ubquitin binding domain in the membrane fusion regulator, Vps9p. Curr. Biol. 13, 258-262 (2003).
-
(2003)
Curr. Biol
, vol.13
, pp. 258-262
-
-
Donaldson, K.M.1
Yin, H.2
Gekakis, N.3
Supek, F.4
Hoazeiro, C.A.5
-
16
-
-
0034667598
-
Proteins of the endoplasmic-retivulum-associated degradation pathway: Domain detection and function prediction
-
Ponting, C.P. Proteins of the endoplasmic-retivulum-associated degradation pathway: Domain detection and function prediction. Biochem. J. 351, 527-535 (2000).
-
(2000)
Biochem. J
, vol.351
, pp. 527-535
-
-
Ponting, C.P.1
-
17
-
-
0345616428
-
A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain
-
Shih, S.C. et al. A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J. 22 1273-1281 (2003).
-
(2003)
EMBO J
, vol.22
, pp. 1273-1281
-
-
Shih, S.C.1
-
18
-
-
34247228197
-
CUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasome
-
Zhang, P.J. et al. CUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasome. EMBO J. 26 1831-1842 (2007).
-
(2007)
EMBO J
, vol.26
, pp. 1831-1842
-
-
Zhang, P.J.1
-
19
-
-
0344222192
-
Sequential DNA damage-independent and -dependent activation of NF-κB by UV
-
Bender, K., Gottlicher, M., Whiteside, S., Rahmsdorf, H.J. & Herrlich, P. Sequential DNA damage-independent and -dependent activation of NF-κB by UV. EMBO J. 17, 5170-5181 (1998).
-
(1998)
EMBO J
, vol.17
, pp. 5170-5181
-
-
Bender, K.1
Gottlicher, M.2
Whiteside, S.3
Rahmsdorf, H.J.4
Herrlich, P.5
-
20
-
-
0032573165
-
Ionizing radiation and short wavelength UV activate NF-κB through two distinct mechanisms
-
Li, N. & Karin, M. Ionizing radiation and short wavelength UV activate NF-κB through two distinct mechanisms. Proc. Natl. Acad. Sci. USA 95, 13012-13017 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13012-13017
-
-
Li, N.1
Karin, M.2
-
21
-
-
0030610362
-
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
-
DiDonato, J.A., Hayakawa, M., Rothwarf, D.M., Zandi, E. & Karin, M. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388, 548-554 (1997).
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
DiDonato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
Zandi, E.4
Karin, M.5
-
22
-
-
0033725155
-
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
-
Devin, A. et al. The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. Immunity 12, 419-429 (2000).
-
(2000)
Immunity
, vol.12
, pp. 419-429
-
-
Devin, A.1
-
23
-
-
0035021123
-
The α and β subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF
-
Devin, A. et al. The α and β subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF. Mol. Cell. Biol. 21, 3986-3994 (2001).
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 3986-3994
-
-
Devin, A.1
-
24
-
-
84925549112
-
The paradigm of IL-6: From basic science to medicine
-
Naka, T., Nishimoto, N. & Kishimoto, T. The paradigm of IL-6: From basic science to medicine. Arthritis Res. 4, S233-S242 (2002).
-
(2002)
Arthritis Res
, vol.4
-
-
Naka, T.1
Nishimoto, N.2
Kishimoto, T.3
-
25
-
-
0034922161
-
The essential role of MEKK3 in TNF-induced NF-κB activation
-
Yang, J. et al. The essential role of MEKK3 in TNF-induced NF-κB activation. Nat. Immunol. 2, 620-624 (2001).
-
(2001)
Nat. Immunol
, vol.2
, pp. 620-624
-
-
Yang, J.1
-
26
-
-
0346496017
-
Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3
-
Huang, Q. et al. Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3. Nat. Immunol. 5, 98-103 (2004).
-
(2004)
Nat. Immunol
, vol.5
, pp. 98-103
-
-
Huang, Q.1
-
27
-
-
0029949257
-
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
-
Hsu, H., Huang, J., Shu, H.B., Baichwal, V. & Goeddel, D.V. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4, 387-396 (1996).
-
(1996)
Immunity
, vol.4
, pp. 387-396
-
-
Hsu, H.1
Huang, J.2
Shu, H.B.3
Baichwal, V.4
Goeddel, D.V.5
-
28
-
-
0032583949
-
Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
-
Nakano, H. et al. Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1. Proc. Natl. Acad. Sci. USA 95, 3537-3542 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 3537-3542
-
-
Nakano, H.1
-
29
-
-
0042467554
-
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
-
Brummelkamp, T.R., Nijman, S.M.B., Dirac, A.M.G. & Bernards, R. Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB. Nature 424, 797-801 (2003).
-
(2003)
Nature
, vol.424
, pp. 797-801
-
-
Brummelkamp, T.R.1
Nijman, S.M.B.2
Dirac, A.M.G.3
Bernards, R.4
-
30
-
-
0041967054
-
The tumour suppressor CYLD negatively regulates NF-κB signaling by deubiquitination
-
Kovalenko, A. et al. The tumour suppressor CYLD negatively regulates NF-κB signaling by deubiquitination. Nature 424, 801-805 (2003).
-
(2003)
Nature
, vol.424
, pp. 801-805
-
-
Kovalenko, A.1
-
31
-
-
0034730713
-
Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice
-
Lee, E.G. et al. Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice. Science 289, 2350-2354 (2000).
-
(2000)
Science
, vol.289
, pp. 2350-2354
-
-
Lee, E.G.1
-
32
-
-
0042467558
-
CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members
-
Trompouki, E. et al. CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members. Nature 424, 793-796 (2003).
-
(2003)
Nature
, vol.424
, pp. 793-796
-
-
Trompouki, E.1
-
33
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signaling
-
Wertz, I.E. et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signaling. Nature 430, 694-699 (2004).
-
(2004)
Nature
, vol.430
, pp. 694-699
-
-
Wertz, I.E.1
-
34
-
-
17544365995
-
The IκB/NF-κB system: A key determinant of mucosalinflammation and protection
-
Jobin, C. & Sartor, R.B. The IκB/NF-κB system: A key determinant of mucosalinflammation and protection. Am. J. Physiol. Cell Physiol. 278, C451-C462 (2000).
-
(2000)
Am. J. Physiol. Cell Physiol
, vol.278
-
-
Jobin, C.1
Sartor, R.B.2
-
35
-
-
0036781052
-
-
Li, Q. & Verma, I.M. NF-κB regulation in the immune system. Nat. Rev. Immunol. 2, 725-734 (2002).
-
Li, Q. & Verma, I.M. NF-κB regulation in the immune system. Nat. Rev. Immunol. 2, 725-734 (2002).
-
-
-
-
36
-
-
0345826130
-
Protein phosphatase 2Cassociation with the IkB kinase complex is involved in regulating NF-κB activity
-
Prajapati, S.S., Verma, U., Yamamoto, Y.M., Kwak, Y.T. & Gaynor, R.B. Protein phosphatase 2Cassociation with the IkB kinase complex is involved in regulating NF-κB activity. J. Biol. Chem. 279, 1739-1746 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 1739-1746
-
-
Prajapati, S.S.1
Verma, U.2
Yamamoto, Y.M.3
Kwak, Y.T.4
Gaynor, R.B.5
-
37
-
-
37349111560
-
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-κB signaling
-
Li, S.T., Wang, L.Y., Berman, M.A., Zhang, Y. & Dorf, M.E. RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-κB signaling. Mol. Cell 24, 497-509 (2006).
-
(2006)
Mol. Cell
, vol.24
, pp. 497-509
-
-
Li, S.T.1
Wang, L.Y.2
Berman, M.A.3
Zhang, Y.4
Dorf, M.E.5
-
38
-
-
33750968212
-
PIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleus
-
Man, J.H. et al. PIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleus. Nucleic Acids Res. 34, 5552-5566 (2006).
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 5552-5566
-
-
Man, J.H.1
-
39
-
-
33646148721
-
Ubc9 interacts with SOX4 and represses its transcriptional activity
-
Pan, X. et al. Ubc9 interacts with SOX4 and represses its transcriptional activity. Biochem. Biophys. Res. Commun. 344 727-734 (2006).
-
(2006)
Biochem. Biophys. Res. Commun
, vol.344
, pp. 727-734
-
-
Pan, X.1
|